Spinal cord infarction: etiology and outcome.

Abstract:

:We reviewed 44 cases of ischemia and infarction of the spinal cord at two university hospitals. Three patients experienced transient ischemic attacks. Etiologies of completed strokes were diverse and included rupture and surgical repair of aortic aneurysms, aortic dissection, aortic rupture and thrombosis, global ischemia, anterior spinal artery embolism, repair and thrombosis of spinal arteriovenous malformations, hematomyelia, epidural hematoma, cervical osteophytosis, celiac plexus block, systemic lupus erythematosus, coagulopathy, and decompression sickness. Motor function improved in 12 patients, was substantial in only one, and occurred largely within the first 2 to 4 weeks. Favorable ambulatory outcome correlated with improving neurologic examinations and relatively preserved strength in hip abductors and knee extensors. More extensive deficits without initial improvement portended a more severe prognosis. Autonomic dysfunction, pain, paresthesia, and depression were common and impeded recovery in some patients. The mean level of deficit was at T-8 and in cases of global ischemia was at T-9, which leads us to dispute the classical view of a midthoracic watershed zone of ischemic vulnerability near T-4.

journal_name

Neurology

journal_title

Neurology

authors

Cheshire WP,Santos CC,Massey EW,Howard JF Jr

doi

10.1212/wnl.47.2.321

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

321-30

issue

2

eissn

0028-3878

issn

1526-632X

journal_volume

47

pub_type

杂志文章
  • Prevalence of ataxia in children: a systematic review.

    abstract:OBJECTIVE:To estimate the prevalence of childhood ataxia resulting from both genetic and acquired causes. METHODS:A systematic review was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement. Five databases were searched for articles reporting a frequency measur...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/01.wnl.0000438224.25600.6c

    authors: Musselman KE,Stoyanov CT,Marasigan R,Jenkins ME,Konczak J,Morton SM,Bastian AJ

    更新日期:2014-01-07 00:00:00

  • Prevalence of AD among whites: a summary by levels of severity.

    abstract:OBJECTIVE:To determine age- and sex-specific AD prevalence rates for whites using each of four severity-based definitions of a case: a person diagnosed as having at least questionable AD, one diagnosed as having at least mild AD, one diagnosed as having moderate or severe AD, and one diagnosed as having severe AD. MET...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.55.2.198

    authors: Hy LX,Keller DM

    更新日期:2000-07-25 00:00:00

  • Brain reserve and cognitive reserve protect against cognitive decline over 4.5 years in MS.

    abstract:OBJECTIVE:Based on the theories of brain reserve and cognitive reserve, we investigated whether larger maximal lifetime brain growth (MLBG) and/or greater lifetime intellectual enrichment protect against cognitive decline over time. METHODS:Forty patients with multiple sclerosis (MS) underwent baseline and 4.5-year fo...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000000433

    authors: Sumowski JF,Rocca MA,Leavitt VM,Dackovic J,Mesaros S,Drulovic J,DeLuca J,Filippi M

    更新日期:2014-05-20 00:00:00

  • Multimodality imaging for improved detection of epileptogenic foci in tuberous sclerosis complex.

    abstract:OBJECTIVE:Using interictal alpha-[11C]methyl-l-tryptophan ([11C]AMT) PET scan, the authors have undertaken a quantitative analysis of all tubers visible on MRI or 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) PET, to determine the relationship between [11C]AMT uptake and epileptic activity on EEG. BACKGROUND:Tuberous scl...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.54.10.1976

    authors: Asano E,Chugani DC,Muzik O,Shen C,Juhász C,Janisse J,Ager J,Canady A,Shah JR,Shah AK,Watson C,Chugani HT

    更新日期:2000-05-23 00:00:00

  • Preclinical memory decline in cognitively normal apolipoprotein E-epsilon4 homozygotes.

    abstract:OBJECTIVE:To determine, in a cross-sectional evaluation of nondemented individuals, if age-related memory decline is influenced by apolipoprotein E (apoE) genotype. BACKGROUND:The apoE-4 allele is an important risk factor for AD. PET in cognitively normal apoE-4 carriers (mean age, 56 years) shows reduced cerebral met...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.53.1.201

    authors: Caselli RJ,Graff-Radford NR,Reiman EM,Weaver A,Osborne D,Lucas J,Uecker A,Thibodeau SN

    更新日期:1999-07-13 00:00:00

  • A prospective study of quality of life in ALS patients treated with noninvasive ventilation.

    abstract::Noninvasive positive pressure ventilation prolongs survival in ALS but its effect on quality of life is unknown. The authors prospectively studied quality of life using the SF-36 questionnaire in a cohort of 16 ventilated patients with ALS. Noninvasive positive pressure ventilation improved scores in the "Vitality" do...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.57.1.153

    authors: Lyall RA,Donaldson N,Fleming T,Wood C,Newsom-Davis I,Polkey MI,Leigh PN,Moxham J

    更新日期:2001-07-10 00:00:00

  • Neurodevelopmental outcome after endovascular treatment of vein of Galen malformations.

    abstract:OBJECTIVE:To assess neurodevelopmental outcome after endovascular treatment of vein of Galen malformations (VOGM). METHODS:Outcome of patients who underwent endovascular treatment for VOGM between 1983 and 2002 was assessed by chart review and parental questionnaires. Development was classified as normal, minor delay ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000094322.12621.02

    authors: Fullerton HJ,Aminoff AR,Ferriero DM,Gupta N,Dowd CF

    更新日期:2003-11-25 00:00:00

  • Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology.

    abstract:OBJECTIVE:To examine the relation of nonsteroidal anti-inflammatory drugs (NSAIDs) to incident Alzheimer disease (AD), change in cognition, and AD pathology. METHODS:Participants were 1,019 older Catholic clergy followed up annually for up to 12 years (mean baseline age = 75.0 years, education = 18.1 years, Mini-Menta...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000313813.48505.86

    authors: Arvanitakis Z,Grodstein F,Bienias JL,Schneider JA,Wilson RS,Kelly JF,Evans DA,Bennett DA

    更新日期:2008-06-03 00:00:00

  • Hypotensive akathisia: autonomic failure associated with leg fidgeting while sitting.

    abstract::The author describes a distinct clinical syndrome in six patients with autonomic failure who manifested habitual, voluntary, transiently suppressible, yet irresistible leg movements occurring only in the sitting position. Keeping the legs still brought on vague symptoms of fatigue, lightheadedness, or apprehension. Re...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.55.12.1923

    authors: Cheshire WP Jr

    更新日期:2000-12-26 00:00:00

  • Coexistence of Lambert-Eaton myasthenic syndrome and subacute cerebellar degeneration: differential effects of treatment.

    abstract::A 61-year-old woman presented with two paraneoplastic neurologic disorders--Lambert-Eaton myasthenic syndrome (LEMS) and subacute cerebellar degeneration (SCD)--that antedated the diagnosis of small-cell carcinoma of the lung by 15 months. Plasmapheresis initiated before the identification of the tumor had a beneficia...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.41.10.1682

    authors: Blumenfeld AM,Recht LD,Chad DA,DeGirolami U,Griffin T,Jaeckle KA

    更新日期:1991-10-01 00:00:00

  • Human muscle proteins: analysis by two-dimensional electrophoresis.

    abstract::Proteins from single frozen sections of human muscle were separated by two-dimensional gel electrophoresis and detected by fluorography or Coomassie Blue staining. The major proteins were identical in different normal muscles obtained from either sex at different ages, and in Duchenne and myotonic dystrophy samples. C...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.33.9.1152

    authors: Giometti CS,Danon MJ,Anderson NG

    更新日期:1983-09-01 00:00:00

  • Subjective versus objective memory change after temporal lobe epilepsy surgery.

    abstract:OBJECTIVE:To examine subjective versus objective memory change after anterior temporal lobectomy (ATL). METHODS:A prospective, controlled study. Controls included 39 unoperated patients with intractable temporal lobe epilepsy (TLE) who were administered a series of cognitive and health-related quality of life measures...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.53.7.1511

    authors: Sawrie SM,Martin RC,Kuzniecky R,Faught E,Morawetz R,Jamil F,Viikinsalo M,Gilliam F

    更新日期:1999-10-22 00:00:00

  • Transient drug-induced abolition of BAEPs in coma.

    abstract::Combined infusion of high doses of lidocaine and thiopental in a comatose patient induced major latency and amplitude BAEP changes, which progressed to complete BAEP abolition. Responses returned to normal after drugs were discontinued. EEGs during the episodes showed long-lasting periods of activity suppression, but ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.38.9.1487

    authors: García-Larrea L,Artru F,Bertrand O,Pernier J,Mauguière F

    更新日期:1988-09-01 00:00:00

  • Initial experiences of US neurologists in practice during the COVID-19 pandemic via survey.

    abstract:OBJECTIVE:To test the hypothesis that US neurologists were experiencing significant challenges with lack of personal protective equipment (PPE), rapid changes in practice, and varying institutional protocols, we conducted this survey study. The current coronavirus disease of 2019 (COVID-19) pandemic has caused widespre...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009844

    authors: Sharma A,Maxwell CR,Farmer J,Greene-Chandos D,LaFaver K,Benameur K

    更新日期:2020-08-04 00:00:00

  • Nonmydriatic ocular fundus photography among headache patients in an emergency department.

    abstract:OBJECTIVES:Determine the frequency of and the predictive factors for abnormal ocular fundus findings among emergency department (ED) headache patients. METHODS:Cross-sectional study of prospectively enrolled adult patients presenting to our ED with a chief complaint of headache. Ocular fundus photographs were obtained...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e31827f0f20

    authors: Thulasi P,Fraser CL,Biousse V,Wright DW,Newman NJ,Bruce BB

    更新日期:2013-01-29 00:00:00

  • Trigeminal sensory neuropathy associated with connective tissue diseases.

    abstract::We reviewed the clinical and laboratory features of 81 patients who had trigeminal sensory neuropathy (TSN) and a connective tissue disease (CTD). The neuropathy developed before the symptoms of CTD in 6/81 patients (7%), and in 38/81 patients (47%) TSN and CTD were diagnosed concurrently. The most frequently associat...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.40.6.891

    authors: Hagen NA,Stevens JC,Michet CJ Jr

    更新日期:1990-06-01 00:00:00

  • Multiple biomarkers covering distinct pathways for predicting outcomes after ischemic stroke.

    abstract:OBJECTIVE:To study the prognostic significance of multiple novel biomarkers in combination after ischemic stroke. METHODS:We derived data from the China Antihypertensive Trial in Acute Ischemic Stroke, and 12 informative biomarkers were measured. The primary outcome was the combination of death and major disability (m...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000006717

    authors: Zhong C,Zhu Z,Wang A,Xu T,Bu X,Peng H,Yang J,Han L,Chen J,Xu T,Peng Y,Wang J,Li Q,Ju Z,Geng D,He J,Zhang Y

    更新日期:2019-01-22 00:00:00

  • Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging.

    abstract::Measurements of cerebral metabolism in patients with Alzheimer's disease (AD) using PET are artifactually depressed due to partial volume averaging of brain tissue activity with enlarged CSF spaces. To investigate the effects of correction for the expansion of CSF spaces on regional metabolic measures, as well as the ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.47.2.454

    authors: Meltzer CC,Zubieta JK,Brandt J,Tune LE,Mayberg HS,Frost JJ

    更新日期:1996-08-01 00:00:00

  • Correlation of muscle biopsy, clinical course, and outcome in PM and sporadic IBM.

    abstract:OBJECTIVE:To correlate muscle biopsy findings with prebiopsy and postbiopsy clinical course and response to therapy in polymyositis (PM) and sporadic inclusion body myositis (IBM). BACKGROUND:Existence of pure PM has recently been questioned; subsequently, the definition and criteria for diagnosing PM were debated. M...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000277527.69388.fe

    authors: Chahin N,Engel AG

    更新日期:2008-02-05 00:00:00

  • Prolonged partial complex status epilepticus: EEG and behavioral observations.

    abstract::Four prolonged episodes of partial complex status epilepticus were observed in a teenaged girl. During each there was an "ictal" phase, in which her mental state frequently fluctuated between mildly clouded consciousness and almost total unresponsiveness; once, she was also blind during this phase of impaired consciou...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.28.9.863

    authors: Engel J Jr,Ludwig BI,Fetell M

    更新日期:1978-09-01 00:00:00

  • Current management of ALS: comparison of the ALS CARE Database and the AAN Practice Parameter. The American Academy of Neurology.

    abstract:BACKGROUND:The American Academy of Neurology (AAN) ALS Practice Parameter was published in April 1999. The ALS CARE Database has been collecting data on the management of patients with ALS in North America since 1996. OBJECTIVE:To compare the management of patients with ALS in North America as recorded in the ALS CARE...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.57.3.500

    authors: Bradley WG,Anderson F,Bromberg M,Gutmann L,Harati Y,Ross M,Miller RG,ALS CARE Study Group.

    更新日期:2001-08-14 00:00:00

  • Mild behavioral impairment is linked to worse cognition and brain atrophy in Parkinson disease.

    abstract:OBJECTIVE:To evaluate the associations of mild behavioral impairment (MBI) with cognitive deficits and patterns of gray matter changes in Parkinson disease (PD). METHODS:Sixty patients with PD without dementia and 29 healthy controls underwent a cognitive neuropsychological evaluation and structural MRI scan. MBI was ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000007968

    authors: Yoon EJ,Ismail Z,Hanganu A,Kibreab M,Hammer T,Cheetham J,Kathol I,Sarna JR,Martino D,Furtado S,Monchi O

    更新日期:2019-08-20 00:00:00

  • Hepatic ketogenesis and muscle carnitine deficiency.

    abstract::The levels of plasma free carnitine and ketone bodies have been found to fluctuate inversely in fasting individuals without muscle disease. Circulating short-chain acyl-carnitines paralleled beta-hydroxybutyrate levels. A patient with lipid storage myopathy and muscle carnitine deficiency, and his two daughters, devel...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.29.6.780

    authors: DiDonato S,Cornelio F,Storchi G,Rimoldi M

    更新日期:1979-06-01 00:00:00

  • Plasmapheresis in multiple sclerosis: preliminary findings.

    abstract::In seven of eight patients with progressive multiple sclerosis subjected to long-term plasmapheresis in combination with azathioprine and pulsed prednisone therapy, we found modest improvement of neurologic function. There was no change in auditory and visual evoked responses or serum demyelinating activity. In six of...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.30.10.1023

    authors: Dau PC,Petajan JH,Johnson KP,Panitch HS,Bornstein MB

    更新日期:1980-10-01 00:00:00

  • Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS.

    abstract:OBJECTIVE:To clarify the genetic, clinicopathologic, and neuroimaging characteristics of patients with hereditary diffuse leukoencephalopathy with spheroids (HDLS) with the colony stimulating factor 1 receptor (CSF-1R) mutation. METHODS:We performed molecular genetic analysis of CSF-1R in patients with HDLS. Detailed ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000000046

    authors: Konno T,Tada M,Tada M,Koyama A,Nozaki H,Harigaya Y,Nishimiya J,Matsunaga A,Yoshikura N,Ishihara K,Arakawa M,Isami A,Okazaki K,Yokoo H,Itoh K,Yoneda M,Kawamura M,Inuzuka T,Takahashi H,Nishizawa M,Onodera O,Kakita

    更新日期:2014-01-14 00:00:00

  • Acoustic reflex abnormalities in cranial-cervical dystonia.

    abstract::Previous anatomic and physiologic studies suggest brainstem dysfunction in cranial-cervical dystonia. To further explore this, we studied suprathreshold acoustic reflex waveforms in 15 such patients. A unique feature of this technique is its ability to reject movement artifacts before averaging the acoustic reflex wav...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.42.3.594

    authors: Lew H,Jordan C,Jerger J,Jankovic J

    更新日期:1992-03-01 00:00:00

  • MRI and neuropsychological differences in early- and late-life-onset geriatric depression.

    abstract::We sought to determine whether geriatric patients with late-life-onset major depression have more subcortical hyperintensities on MRI and greater cognitive impairment than age-matched geriatric patients with early-life-onset major depression, suggesting that subcortical disease may be etiologic in late-life depression...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.46.6.1567

    authors: Salloway S,Malloy P,Kohn R,Gillard E,Duffy J,Rogg J,Tung G,Richardson E,Thomas C,Westlake R

    更新日期:1996-06-01 00:00:00

  • Clinical and prognostic subforms of new daily-persistent headache.

    abstract:BACKGROUND:According to the International Classification of Headache Disorders (ICHD)-2, primary daily headaches unremitting from onset are classified as new daily-persistent headache (NDPH) only if migraine features are absent. When migraine features are present, classification is problematic. METHODS:We developed a ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3181dad5de

    authors: Robbins MS,Grosberg BM,Napchan U,Crystal SC,Lipton RB

    更新日期:2010-04-27 00:00:00

  • Efficient neurophysiologic selection of X-linked Charcot-Marie-Tooth families: ten novel mutations.

    abstract:OBJECTIVE:To devise a neurophysiologic strategy to select X-linked Charcot-Marie-Tooth neuropathy syndrome (CMTX) families for connexin 32 mutation screening. BACKGROUND:Once the common chromosome 17 DNA duplication (CMT1A syndrome) has been excluded, clinical features are not sufficiently distinctive to select which ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.51.5.1412

    authors: Nicholson GA,Yeung L,Corbett A

    更新日期:1998-11-01 00:00:00

  • Dantrolene sodium and hepatic injury.

    abstract::This is a report on hepatic adverse events associated with dantrolene therapy. All cases reported to the manufacturer are included, from all sources, through 1987. Of 122 cases containing sufficient data to analyze, 47 patients had asymptomatic transaminase elevations, 12 had additional mild (less than or equal to 2.5...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.40.9.1427

    authors: Chan CH

    更新日期:1990-09-01 00:00:00