Dantrolene sodium and hepatic injury.

abstract：:We analyzed the frequency of cardiac embolic sources in 62 patients with acute lacunar stroke vs 50 controls. In post hoc analysis, 11 patients with lacunar stroke having neither hypertension nor diabetes mellitus (non-HDM group) had a higher frequency of right-to-left shunt (RLS) (82%) than patients with risk factors...

journal_title：Neurology

authors： Ueno Y,Kimura K,Iguchi Y,Shibazaki K,Inoue T,Urabe T

更新日期：2007-02-13 00:00:00

abstract：BACKGROUND:Galantamine is a reversible, competitive cholinesterase inhibitor that also allosterically modulates nicotinic acetylcholine receptors. These mechanisms of action provided the rationale for a therapeutic trial of galantamine in AD. METHODS:A 6-month, multicenter, double-blind trial was undertaken in 636 pat...

journal_title：Neurology

authors： Raskind MA,Peskind ER,Wessel T,Yuan W

更新日期：2000-06-27 00:00:00

abstract：OBJECTIVE:To describe four patients with temporal lobe epilepsy with limbic encephalitis unrelated to neoplasm. METHODS:The authors performed a retrospective evaluation of patient data obtained during presurgical evaluation, with additional CSF analyses, serum analyses, and histopathologic investigations. RESULTS:The...

journal_title：Neurology

authors： Bien CG,Schulze-Bonhage A,Deckert M,Urbach H,Helmstaedter C,Grunwald T,Schaller C,Elger CE

更新日期：2000-12-26 00:00:00

abstract：OBJECTIVE:To combine MRI-based cortical morphometry and diffusion white matter tractography to describe the anatomical correlates of repetition deficits in patients with primary progressive aphasia (PPA). METHODS:The traditional anatomical model of language identifies a network for word repetition that includes Wernic...

journal_title：Neurology

authors： Forkel SJ,Rogalski E,Drossinos Sancho N,D'Anna L,Luque Laguna P,Sridhar J,Dell'Acqua F,Weintraub S,Thompson C,Mesulam MM,Catani M

更新日期：2020-02-11 00:00:00

abstract：:Subarachnoid neurolysis using ethanol to destroy selectively the posterior roots of the spinal cord is a method for providing pain relief in patients with advanced cancer. Weakness of the extremities is a complication of the procedure that has been attributed to spread of the neurolytic agent to the anterior roots. Th...

journal_title：Neurology

authors： McGarvey ML,Ferrante FM,Patel RS,Maljian JA,Stecker M

更新日期：2000-04-11 00:00:00

abstract：:The present study quantitatively assessed volumes of the amygdala and its subnuclei in autopsied cases of advanced Alzheimer's disease (AD) for comparison with age-matched controls. Amygdalar nuclei showed significant atrophy in AD with the exception of the paralaminar portion of the basal nucleus. The magnocellular r...

journal_title：Neurology

authors： Scott SA,DeKosky ST,Scheff SW

更新日期：1991-03-01 00:00:00

abstract：:Family studies of primary torsion dystonia have used the diagnostic categories of definite, probable, and possible dystonia for gene mapping and identification, but the validity of this hierarchical classification is not known. The authors assessed 147 DYT1 GAG deletion carriers and 113 blood-related noncarriers from ...

journal_title：Neurology

authors： Bressman SB,Raymond D,Wendt K,Saunders-Pullman R,De Leon D,Fahn S,Ozelius L,Risch N

更新日期：2002-12-10 00:00:00

abstract：:Minor head trauma precipitated oculomotor nerve palsies in two patients who subsequently were discovered to have ipsilateral posterior communicating artery aneurysms. A history of minor trauma should not dissuade investigation for underlying causes of oculomotor nerve palsy, including intracranial aneurysm. ...

journal_title：Neurology

authors： Walter KA,Newman NJ,Lessell S

更新日期：1994-01-01 00:00:00

abstract：:Oligoclonal bands ( OCBs ) were examined in CSF from 23 normal controls, 8 cases of inflammatory neurologic diseases, 24 cases of noninflammatory neurologic diseases, 27 sporadic cases of MS, and the 29 MS twin pairs, by isoelectric focusing followed by silver staining or western transblotting and immunoperoxidase sta...

journal_title：Neurology

authors： Xu XH,McFarlin DE

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:To report five stroke patients with sensory deficits including prominent chest discomfort mimicking angina. BACKGROUND:Chest wall sensory discomfort, as a part of unilateral sensory dysfunction, has seldom been recognized as a potential imitator of cardiac ischemia. METHODS:A retrospective review of stroke ...

journal_title：Neurology

authors： Gorson KC,Pessin MS,DeWitt LD,Caplan LR

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that patients with multiple sclerosis (MS) with intereye asymmetry on low contrast letter acuity, and thickness of the retinal nerve fiber layer (RNFL), would exhibit corresponding changes in cortical timing and amplitude responses on pattern reversal multifocal visual evoked potentials...

journal_title：Neurology

authors： Frohman AR,Schnurman Z,Conger A,Conger D,Beh S,Greenberg B,Sutter E,Calabresi PA,Balcer LJ,Frohman TC,Frohman EM

更新日期：2012-08-21 00:00:00

abstract：:The objective of this study was to use high-resolution MRI techniques to determine whether children with Down syndrome exhibit decreases in hippocampal and amygdala volumes similar to those demonstrated in recent studies of adults with this condition. When corrected for overall brain volumes, amygdala volumes did not ...

journal_title：Neurology

authors： Pinter JD,Brown WE,Eliez S,Schmitt JE,Capone GT,Reiss AL

更新日期：2001-04-10 00:00:00

abstract：:Spontaneous circadian fluctuations of motor symptoms in Parkinson's disease (PD) often occur, with dysfunction typically less severe in the early morning than in the afternoon. In 23 PD patients with or without a history of circadian motor fluctuations, we studied contrast sensitivity (CS), a non-motor function, consi...

journal_title：Neurology

authors： Struck LK,Rodnitzky RL,Dobson JK

更新日期：1990-03-01 00:00:00

abstract：:The association of APOE genotypes with cerebral microbleeds (CMBs) was examined on the basis of the location of CMBs in 414 patients who were admitted primarily because of stroke. With respect to possession of the epsilon2 or epsilon4 allele, the adjusted odds ratio was 1.94 (1.05 to 3.58) for lobar CMBs but 1.21 (0.6...

journal_title：Neurology

authors： Kim M,Bae HJ,Lee J,Kang L,Lee S,Kim S,Lee JE,Lee KM,Yoon BW,Kwon O,Koo JS,Kim BK

更新日期：2005-11-08 00:00:00

abstract：:The mechanism by which prednisone improves muscle strength and function in Duchenne muscular dystrophy (DMD) is unknown. We addressed the possibility that clinical improvement was related to prednisone-induced alterations in skeletal muscle dystrophin. We performed muscle biopsies on patients at the conclusion of a ra...

journal_title：Neurology

authors： Burrow KL,Coovert DD,Klein CJ,Bulman DE,Kissel JT,Rammohan KW,Burghes AH,Mendell JR

更新日期：1991-05-01 00:00:00

abstract：:Cytokines such as interleukin-1 and tumor necrosis factor are involved in the triggering of the immune response, induction of acute inflammatory events, and transition to, or persistence of, chronic inflammation. The action of proinflammatory cytokines is regulated by their receptor expression, downregulation and shed...

journal_title：Neurology

authors： Burger D,Dayer JM

更新日期：1995-06-01 00:00:00

abstract：:We studied four patients with neurologic disorders of the lumbosacral plexus. Except for location of symptoms, the disorder confirmed to criteria established for the clinical diagnosis of brachial plexus neuritis. Acute onset of pain in one or both legs was followed by weakness, loss of stretch reflexes, and sometimes...

journal_title：Neurology

authors： Sander JE,Sharp FR

更新日期：1981-04-01 00:00:00

abstract：:Using diagnostic criteria from the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, dementia was clinically diagnosed in 57 (62%) of 92 centenarians living in two northern Italian provinces. The condition was severely disabling in approximately 70% of the demented patients. Although clinica...

journal_title：Neurology

authors： Ravaglia G,Forti P,De Ronchi D,Maioli F,Nesi B,Cucinotta D,Bernardi M,Cavalli G

更新日期：1999-07-22 00:00:00

abstract：:We measured the concentrations of the monoamines, their precursors, and their metabolites, and the activity of choline acetyltransferase (ChAT) in basal ganglia and cortical regions of postmortem brains from cases with histologically verified pure Alzheimer's disease (AD), AD with diffusely distributed Lewy bodies (Le...

journal_title：Neurology

authors： Langlais PJ,Thal L,Hansen L,Galasko D,Alford M,Masliah E

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To assess the genetic contribution of TBK1, a gene implicated in amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and FTD-ALS, in Belgian FTD and ALS patient cohorts containing a significant part of genetically unresolved patients. METHODS:We sequenced TBK1 in a hospital-based cohort of 48...

journal_title：Neurology

authors： Gijselinck I,Van Mossevelde S,van der Zee J,Sieben A,Philtjens S,Heeman B,Engelborghs S,Vandenbulcke M,De Baets G,Bäumer V,Cuijt I,Van den Broeck M,Peeters K,Mattheijssens M,Rousseau F,Vandenberghe R,De Jonghe P,Cras P

更新日期：2015-12-15 00:00:00

abstract：:Acute chorea in a child followed ingestion of pemoline mesylate. In guinea pigs, in an experimental model of chorea, chronic administration of pemoline induced behavioral supersensitivity to other dopaminergic agonists. Pemoline is similar to both d-amphetamine and methylphenidate in altering central dopaminergic sens...

journal_title：Neurology

authors： Nausieda PA,Koller WC,Weiner WJ,Klawans HL

更新日期：1981-03-01 00:00:00

abstract：:We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26%...

journal_title：Neurology

authors： Cascino GD,Hirschorn KA,Jack CR,Sharbrough FW

更新日期：1989-08-01 00:00:00

abstract：:Creutzfeldt-Jakob disease was studied among Libyan-born Israelis, in whom the disease appears with unusual frequency. Interviews with relatives of deceased victims revealed statistically significant clustering within families. The results suggest either a common source of exposure or a genetic influence on susceptibil...

journal_title：Neurology

authors： Neugut RH,Neugut AI,Kahana E,Stein Z,Alter M

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Genetic studies of PD frequently rely on family history interviews (FHI), yet the accuracy of data obtained in this way is unclear. OBJECTIVE:To assess the interinformant reliability and validity of family history information on PD in first-degree relatives of PD cases and controls. METHODS:A structured FH...

journal_title：Neurology

authors： Marder K,Levy G,Louis ED,Mejia-Santana H,Cote L,Andrews H,Harris J,Waters C,Ford B,Frucht S,Fahn S,Ottman R

更新日期：2003-07-08 00:00:00

abstract：BACKGROUND:Ependymoma is a rare type of glioma, representing 5% of all CNS malignancies. Radiotherapy (RT) is commonly administered, but there is no standard chemotherapy. At recurrence, ependymoma is notoriously refractory to therapy and the prognosis is poor. In recurrent glioblastoma, encouraging responses with beva...

journal_title：Neurology

authors： Green RM,Cloughesy TF,Stupp R,DeAngelis LM,Woyshner EA,Ney DE,Lassman AB

更新日期：2009-11-17 00:00:00

abstract：:We previously reported a large Charcot-Marie-Tooth family not linked to the Duffy blood group marker, supporting the existence of genetic heterogeneity in this neuropathy. In order to investigate the possibility of another disease locus on chromosome 1, we analyzed this family further, using DNA polymorphisms of 6 gen...

journal_title：Neurology

authors： Raeymaekers P,De Jonghe P,Backhovens H,Wehnert A,De Winter G,Swerts L,Gheuens J,Martin JJ,Vandenberghe A,Van Broeckhoven C

更新日期：1989-06-01 00:00:00

abstract：:A 33-year-old man with complex partial seizures developed de novo hypertension after the initiation of carbamazepine, which resolved on discontinuation. Although rare, a variety of cardiovascular effects including hypertension have been reported with carbamazepine. Numerous mechanisms may be responsible; however, shar...

journal_title：Neurology

authors： Jette N,Veregin T,Guberman A

更新日期：2002-07-23 00:00:00

abstract：BACKGROUND:Timely recruiting and retaining participants into Alzheimer disease (AD) clinical trials is a challenge. We used conjoint analysis to identify how alterations in attributes of clinical trial design improve willingness to participate: risk, home visits, car service, or increased chance of receiving interventi...

journal_title：Neurology

authors： Karlawish J,Cary MS,Rubright J,Tenhave T

更新日期：2008-12-02 00:00:00

abstract：:Information on 1,343 hospitalized patients in the Cornell Neurology Database with final diagnoses of transient ischemic attacks (TIA), reversible ischemic neurologic deficits (RIND), or ischemic stroke was examined in order to determine the duration of ischemic deficits. Episodes resolved within the first 24 hours (cl...

journal_title：Neurology

authors： Levy DE

更新日期：1988-05-01 00:00:00

abstract：:Cognitive impairment is a frequent manifestation of advanced human immunodeficiency virus (HIV) infection. The response to antiretroviral medication is often partial and poorly sustained. Recent studies suggest that free radical production within the CNS and neuronal apoptosis may play important roles in the pathogene...

journal_title：Neurology

authors：

更新日期：1998-03-01 00:00:00