Prolonged partial complex status epilepticus: EEG and behavioral observations.

abstract：OBJECTIVES:The aim of this study was to identify risk factors for rupture of unruptured cerebral aneurysms (UCAs) in elderly Japanese patients aged 70 years or older. METHODS:The participants included all patients 70 years of age or older in 3 prospective studies in Japan (the Unruptured Cerebral Aneurysm Study of Jap...

journal_title：Neurology

authors： Hishikawa T,Date I,Tokunaga K,Tominari S,Nozaki K,Shiokawa Y,Houkin K,Murayama Y,Ishibashi T,Takao H,Kimura T,Nakayama T,Morita A,For UCAS Japan and UCAS II Investigators.

更新日期：2015-11-24 00:00:00

abstract：:Genetic factors are important in Alzheimer disease (AD) and Parkinson disease but have not been well characterized in Lewy body dementia (LBD). The authors obtained family history in patients from an autopsy series of AD and LBD and in living healthy controls. A family history of dementia was more common in both LBD a...

journal_title：Neurology

authors： Woodruff BK,Graff-Radford NR,Ferman TJ,Dickson DW,DeLucia MW,Crook JE,Arvanitakis Z,Brassler S,Waters C,Barker W,Duara R

更新日期：2006-06-27 00:00:00

abstract：:We administered a battery of cognitive tests to 41 recently diagnosed Parkinson patients and 41 controls to assess the early neuropsychological changes associated with Parkinson's disease (PD). Parkinson subjects did as well as controls on tasks assessing attention and select language and visuospatial measures. Howeve...

journal_title：Neurology

authors： Levin BE,Llabre MM,Weiner WJ

更新日期：1989-04-01 00:00:00

abstract：:Generic substitution is practiced widely in both hospital and community settings. There have been several reports of reduced serum concentrations and seizure exacerbation following generic substitution of Tegretol. We describe the first 2 cases of carbamazepine toxicity resulting from the substitution of Tegretol with...

journal_title：Neurology

authors： Gilman JT,Alvarez LA,Duchowny M

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To determine the prognostic value of selected biomarkers in clinically isolated syndromes (CIS) for conversion to multiple sclerosis (MS) and disability accrual. METHODS:Data were acquired from 2 CIS cohorts. The screening phase evaluated patients developing clinically definite MS (CIS-CDMS) and patients who...

journal_title：Neurology

authors： Arrambide G,Espejo C,Eixarch H,Villar LM,Alvarez-Cermeño JC,Picón C,Kuhle J,Disanto G,Kappos L,Sastre-Garriga J,Pareto D,Simon E,Comabella M,Río J,Nos C,Tur C,Castilló J,Vidal-Jordana A,Galán I,Arévalo MJ,Auger C

更新日期：2016-09-13 00:00:00

abstract：OBJECTIVE:The purpose of this study was to develop an algorithm incorporating MRI metrics to classify patients with mild traumatic brain injury (mTBI) and controls. METHODS:This was an institutional review board-approved, Health Insurance Portability and Accountability Act-compliant prospective study. We recruited pat...

journal_title：Neurology

authors： Lui YW,Xue Y,Kenul D,Ge Y,Grossman RI,Wang Y

更新日期：2014-09-30 00:00:00

abstract：:Since the introduction of computed tomography (CT), there have been numerous reports of brain abscess treated successfully without surgery. Because pathologic confirmation was lacking in these patients, diagnosis was based on CT abnormalities, usually ring enhancement. However, our recent clinical experience and the e...

journal_title：Neurology

authors： Dobkin JF,Healton EB,Dickinson PC,Brust JC

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVE:To assess the clinical relevance of a positive voltage-gated potassium channel (VGKC) test in patients lacking antibodies to LGI1 and Caspr2. METHODS:VGKC-positive patients were tested for LGI1 and Caspr2 antibodies. Patients lacking both antibodies were matched (1:2) to VGKC-negative patients. Clinical and ...

journal_title：Neurology

authors： van Sonderen A,Schreurs MW,de Bruijn MA,Boukhrissi S,Nagtzaam MM,Hulsenboom ES,Enting RH,Thijs RD,Wirtz PW,Sillevis Smitt PA,Titulaer MJ

更新日期：2016-05-03 00:00:00

abstract：BACKGROUND:The use of volumetric MRI as a biomarker for assessing transitions to dementia presumes that more rapid brain loss marks the clinical transition from benign aging to mild cognitive impairment (MCI). The trajectory of this volume loss relative to the timing of the clinical transition to dementia has not been ...

journal_title：Neurology

authors： Carlson NE,Moore MM,Dame A,Howieson D,Silbert LC,Quinn JF,Kaye JA

更新日期：2008-03-11 00:00:00

abstract：:There are several reports of a defect of complex I in the substantia nigra (SN) of Parkinson's disease (PD) patients. To evaluate whether this is specific to dopaminergic neurons or the phenotypically relevant consequence of a widespread failure of the mitochondrial oxidative phosphorylation (OXPHOS) system, we measur...

journal_title：Neurology

authors： DiDonato S,Zeviani M,Giovannini P,Savarese N,Rimoldi M,Mariotti C,Girotti F,Caraceni T

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:To investigate the role of blocking antibodies in neonatal Guillain-Barré syndrome (GBS) occurring 12 days postpartum in a child born to a mother with ongoing GBS. METHODS:We studied plasma filtrate, purified IgG, and monovalent Fab fragments from the affected mother and serum from the neonate as well as ser...

journal_title：Neurology

authors： Buchwald B,de Baets M,Luijckx GJ,Toyka KV

更新日期：1999-10-12 00:00:00

abstract：:Previous brain infarctions seen on CT are common in the absence of history of stroke. Eleven percent of patients (135/1,203) without stroke history had ischemic lesions on their first CT, unrelated to the presenting stroke. Stroke Data Bank files were reviewed to determine whether the occurrence, location, and CT char...

journal_title：Neurology

authors： Chodosh EH,Foulkes MA,Kase CS,Wolf PA,Mohr JP,Hier DB,Price TR,Furtado JG Jr

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:To assess the inpatient hospitalization burden and costs of patients with autoimmune encephalitis (AE) at a tertiary care institution. METHODS:Adult inpatients with AE were identified retrospectively from July 1, 2005, to June 30, 2015. Demographic and clinical data were collected and analyzed. Billing data ...

journal_title：Neurology

authors： Cohen J,Sotoca J,Gandhi S,Yeshokumar AK,Gordon-Lipkin E,Geocadin RG,Frick KD,Probasco JC,Venkatesan A

更新日期：2019-02-26 00:00:00

abstract：:We found an antinuclear antibody highly restricted to nuclei of neurons in two patients with subacute sensory neuronopathy complicating oat cell carcinoma of the lung. Serum was tested by indirect immunofluorescence and immunoperoxidase staining. At low concentrations of antibody, only the nuclei of the neurons were s...

journal_title：Neurology

authors： Graus F,Cordon-Cardo C,Posner JB

更新日期：1985-04-01 00:00:00

abstract：:Thirty-eight survivors from among 117 patients hospitalized after out-of-hospital cardiac arrest were evaluated approximately 3 1/2 years later. Twenty patients were living; 18 had died. Fifty-three percent had resumed independent social activities, but only 32% had returned to work. Eight of 14 patients tested were n...

journal_title：Neurology

authors： Earnest MP,Yarnell PR,Merrill SL,Knapp GL

更新日期：1980-12-01 00:00:00

abstract：:In 41 cases of verified ruptured saccular aneurysm, we prospectively predicted the presence or absence of delayed symptomatic cerebral vasospasm. CT criteria quantifying the extent and location of subarachnoid blood (developed in our previous retrospective study) were used in this prospective series of patients. Twent...

journal_title：Neurology

authors： Kistler JP,Crowell RM,Davis KR,Heros R,Ojemann RG,Zervas T,Fisher CM

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVE:To compare the effects of carbamazepine and lamotrigine monotherapy for people with partial onset seizures or generalized onset tonic-clonic seizures. METHODS:A systematic review and meta-analysis using data on individual patients from randomized trials comparing lamotrigine with carbamazepine monotherapy. T...

journal_title：Neurology

authors： Gamble C,Williamson PR,Chadwick DW,Marson AG

更新日期：2006-05-09 00:00:00

abstract：OBJECTIVE:To critically re-evaluate cases diagnosed as adult neuronal ceroid lipofuscinosis (ANCL) in order to aid clinicopathologic diagnosis as a route to further gene discovery. METHODS:Through establishment of an international consortium we pooled 47 unsolved cases regarded by referring centers as ANCL. Clinical a...

journal_title：Neurology

authors： Berkovic SF,Staropoli JF,Carpenter S,Oliver KL,Kmoch S,Anderson GW,Damiano JA,Hildebrand MS,Sims KB,Cotman SL,Bahlo M,Smith KR,Cadieux-Dion M,Cossette P,Jedličková I,Přistoupilová A,Mole SE,ANCL Gene Discovery Consortiu

更新日期：2016-08-09 00:00:00

abstract：OBJECTIVE:To assess the expression of heat shock proteins (HSP) in glioma cells in vitro and in vivo and to examine their role in resistance to apoptosis. BACKGROUND:HSP are expressed in response to various forms of stress. Constitutive HSP expression may confer resistance to cytotoxic stimuli in human cancers. METHO...

journal_title：Neurology

authors： Hermisson M,Strik H,Rieger J,Dichgans J,Meyermann R,Weller M

更新日期：2000-03-28 00:00:00

abstract：OBJECTIVE:To investigate the safety and efficacy of escalating doses of the semi-synthetic triterpenoid omaveloxolone in patients with mitochondrial myopathy. METHODS:In cohorts of 8-13, 53 participants were randomized double-blind to 12 weeks of treatment with omaveloxolone 5, 10, 20, 40, 80, or 160 mg, or placebo. O...

journal_title：Neurology

authors： Madsen KL,Buch AE,Cohen BH,Falk MJ,Goldsberry A,Goldstein A,Karaa A,Koenig MK,Muraresku CC,Meyer C,O'Grady M,Scaglia F,Shieh PB,Vockley J,Zolkipli-Cunningham Z,Haller RG,Vissing J

更新日期：2020-02-18 00:00:00

abstract：:Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From a cohort of 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken for typing of class I and II major histocompatibility antigens. The f...

journal_title：Neurology

authors： Kemler MA,van de Vusse AC,van den Berg-Loonen EM,Barendse GA,van Kleef M,Weber WE

更新日期：1999-10-12 00:00:00

abstract：OBJECTIVE:To investigate clinical differences in warm and cold complex regional pain syndrome (CRPS) phenotypes. BACKGROUND:CRPS represents inhomogeneous chronic pain conditions; approximately 70% patients with CRPS have "warm" affected limbs and 30% have "cold" affected limbs. METHODS:We examined 50 patients with "c...

journal_title：Neurology

authors： Eberle T,Doganci B,Krämer HH,Geber C,Fechir M,Magerl W,Birklein F

更新日期：2009-02-10 00:00:00

abstract：:The ability of two noninvasive diagnostic methods--oculoplethysmography-carotid phonoangiography (OPG/CPA) and directional Doppler ultrasonography--to detect extracranial cerebrovascular disease was examined in 400 consecutive studies. Cerebral arteriography was performed in 74 patients. Transient ischemic attack was ...

journal_title：Neurology

authors： Ginsberg MD,Greenwood SA,Goldberg HI

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To compare the sensitivity of structural MRI and 18F-fludeoxyglucose PET (18FDG-PET) to detect longitudinal changes in frontotemporal dementia (FTD). METHODS:Thirty patients with behavioral variant FTD (bvFTD), 7 with nonfluent/agrammatic variant primary progressive aphasia (nfvPPA), 16 with semantic variant...

journal_title：Neurology

authors： Bejanin A,Tammewar G,Marx G,Cobigo Y,Iaccarino L,Kornak J,Staffaroni AM,Dickerson BC,Boeve BF,Knopman DS,Gorno-Tempini M,Miller BL,Jagust WJ,Boxer AL,Rosen HJ,Rabinovici GD

更新日期：2020-07-14 00:00:00

abstract：:INeuro@neurolist.mcg. edu: An e-mail discussion list for neurologists Neuro@neurolist.mcg.edu (Neurolist) is a discussion list for neurologists. This Internet tool, established in 1994, allows the worldwide community of neurologists to communicate quickly and efficiently using e-mail, web browsers, and newsreaders. Ne...

journal_title：Neurology

authors： Rivner MH

更新日期：1999-06-10 00:00:00

abstract：:The motor effects of direct agonists which act selectively on certain dopamine receptors were studied in monkeys rendered hemiparkinsonian by unilateral intracarotid injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The D-2 dopamine agonist, LY 171555, but not the D-1 agonist, SKF 38393, reduced parkin...

journal_title：Neurology

authors： Barone P,Bankiewicz KS,Corsini GU,Kopin IJ,Chase TN

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:This study was conducted to determine the relationship of frontal lobe cortical thickness and basal ganglia volumes to measures of cognition in adults with sickle cell anemia (SCA). METHODS:Participants included 120 adults with SCA with no history of neurologic dysfunction and 33 healthy controls (HCs). Part...

journal_title：Neurology

authors： Mackin RS,Insel P,Truran D,Vichinsky EP,Neumayr LD,Armstrong FD,Gold JI,Kesler K,Brewer J,Weiner MW,Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group.

更新日期：2014-03-11 00:00:00

abstract：:In the same family, the generalized or infantile form of acid maltase deficiency (glycogenosis type II, Pompe disease) and the muscular or adult-onset form affected different individuals. Autosomal-recessive inheritance for the two clinical forms was demonstrated in this family by assay of acid alpha-glucosidase in mu...

journal_title：Neurology

authors： Loonen MC,Busch HF,Koster JF,Martin JJ,Niermeijer MF,Schram AW,Brouwer-Kelder B,Mekes W,Slee RG,Tager JM

更新日期：1981-10-01 00:00:00

abstract：:Apraxia is the loss of the ability to perform learned skilled movements correctly. In right-handers, apraxia and aphasia are most frequently associated with left-hemisphere lesions. When they are dissociated, however, aphasia is more common in the absence of apraxia than vice versa. There are two hypotheses that can a...

journal_title：Neurology

authors： Foundas AL,Henchey R,Gilmore RL,Fennell EB,Heilman KM

更新日期：1995-07-01 00:00:00

abstract：:A 12-year-old girl developed simple partial motor and sensory seizures due to a right perirolandic astrocytoma. Subdural EEG recording and functional stimulation disclosed close correlation between EEG-clinical manifestations of focal seizures and functional responses to cortical stimulation. This case supports the id...

journal_title：Neurology

authors： Arroyo S,Krauss GL,Lesser RP,Gordon B,Hart J Jr,Carson BS,Uematsu S

更新日期：1992-03-01 00:00:00