Abstract:
OBJECTIVE:To test the hypothesis that US neurologists were experiencing significant challenges with lack of personal protective equipment (PPE), rapid changes in practice, and varying institutional protocols, we conducted this survey study. The current coronavirus disease of 2019 (COVID-19) pandemic has caused widespread disease and death. Rapid increases in patient volumes have exposed weaknesses in health care systems and challenged our ability to provide optimal patient care and adequate safety measures to health care workers (HCWs). METHODS:A 36-item survey was distributed to neurologists around the United States through various media platforms. RESULTS:Over a 1-week period, 567 responses were received. Of these, 56% practiced in academia. A total of 87% had access to PPE, with 45% being asked to reuse PPE due to shortages. The pandemic caused rapid changes in practice, most notably a shift toward providing care by teleneurology, although a third experienced challenges in transitioning to this model. Wide variations were noted both in testing and in the guidance provided for the exposed, sick, or vulnerable HCWs. Notably, 59% of respondents felt that their practices were doing what they could, although 56% did not feel safe taking care of patients. CONCLUSIONS:Results from our survey demonstrate significant variability in preparedness and responsiveness to the COVID-19 pandemic in neurology, affected by region, health care setting, and practice model. Practice guidelines from professional societies and other national entities are needed to improve protection for physicians and their patients, promote recommended practice changes during a pandemic, and optimize future preparedness for public health emergencies.
journal_name
Neurologyjournal_title
Neurologyauthors
Sharma A,Maxwell CR,Farmer J,Greene-Chandos D,LaFaver K,Benameur Kdoi
10.1212/WNL.0000000000009844subject
Has Abstractpub_date
2020-08-04 00:00:00pages
215-220issue
5eissn
0028-3878issn
1526-632Xpii
WNL.0000000000009844journal_volume
95pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::The effect of imipramine on the absorption of a single dose of levodopa was studied in male volunteers. By delaying gastric emptying and retarding delivery to intestinal absorptive sites, imipramine interfered with the absorption of levodopa. This action caused by the anticholinergic effect of imipramine. The retardat...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.25.11.1029
更新日期:1975-11-01 00:00:00
abstract::Noninvasive positive pressure ventilation prolongs survival in ALS but its effect on quality of life is unknown. The authors prospectively studied quality of life using the SF-36 questionnaire in a cohort of 16 ventilated patients with ALS. Noninvasive positive pressure ventilation improved scores in the "Vitality" do...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.1.153
更新日期:2001-07-10 00:00:00
abstract::Many advances in prevention, diagnosis, and treatment of neurologic disease have emerged in the last few decades, resulting in reduced mortality and decreased disability. However, these advances have not benefitted all populations equally. A growing body of evidence indicates that barriers to care fall along racial an...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0000000000006874
更新日期:2019-02-05 00:00:00
abstract:OBJECTIVES:To study the effects of head injury on disease progression and on neuropathologic outcomes in amyotrophic lateral sclerosis (ALS). METHODS:Patients with ALS were surveyed to obtain head injury history, and medical records were reviewed. Linear regression was performed to determine if head injury was a predi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001522
更新日期:2015-04-28 00:00:00
abstract::We report on the prevalence of dementia in Canadians age 85 years and older. The purpose of this study was to determine whether the prevalence of dementia continued to increase in the very old, and to define the types of dementia and their relative proportions in this age group. We collected data as part of the Canadi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.9.1593
更新日期:1994-09-01 00:00:00
abstract::Thirteen patients presented with brief, repetitive, stereotyped transient ischemic attacks, large artery atherostenoses or occlusions with impaired collateral flow to a cortical perfusion borderzone, and orthostatic hypotension (OH). OH was caused by diabetes mellitus, aging, and treatments for ischemic heart disease ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.39.1.30
更新日期:1989-01-01 00:00:00
abstract::We reviewed the prognostic significance of preoperative EEG findings in 25 patients who underwent functional hemispherectomy. Bilateral independent epileptogenic foci, found in five patients, generally indicate a less satisfactory outcome, with only three of the five patients becoming seizure free following hemisphere...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.41.11.1790
更新日期:1991-11-01 00:00:00
abstract:OBJECTIVE:To perform a psychometric evaluation of the inflammatory neuropathy cause and treatment (INCAT) sensory sumscore (ISS) in sensory-motor immune-mediated polyneuropathies. This new sensory scale was evaluated to strive for uniformity in assessing sensory deficit in these disorders. METHODS:The ISS comprises vi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.54.4.943
更新日期:2000-02-22 00:00:00
abstract:OBJECTIVE:To describe a clinical syndrome of cerebellar ataxia associated with muscle coenzyme Q10 (CoQ10) deficiency. BACKGROUND:Muscle CoQ10 deficiency has been reported only in a few patients with a mitochondrial encephalomyopathy characterized by 1) recurrent myoglobinuria; 2) brain involvement (seizures, ataxia, ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.56.7.849
更新日期:2001-04-10 00:00:00
abstract::Mutations in DJ-1 are a cause of autosomal recessive parkinsonism. Polymorphism of genes implicated in hereditary forms of parkinsonism may be a predisposing factor in sporadic Parkinson's disease (PD). The authors analyzed whether a polymorphism (g.168_185del) within exon 1 of DJ-1 contributes to the risk of sporadic...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000083992.28066.7e
更新日期:2003-10-14 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of eptinezumab, a humanized anti-calcitonin gene-related peptide monoclonal antibody, in the preventive treatment of chronic migraine (CM). METHODS:The Prevention of Migraine via Intravenous ALD403 Safety and Efficacy-2 (PROMISE-2) study was a phase 3, multicenter, randomi...
journal_title:Neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1212/WNL.0000000000009169
更新日期:2020-03-31 00:00:00
abstract::We studied a family with an extrapyramidal disorder characterized by childhood onset of lower-limb and axial dystonia, followed by parkinsonism. Dramatic response to levodopa therapy and minimal progression in adult life was seen. The family included five generations of affected members of both sexes in an autosomal d...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.11.1424
更新日期:1986-11-01 00:00:00
abstract:OBJECTIVE:To report 2 patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who presented acutely with Miller Fisher syndrome and polyneuritis cranialis, respectively. METHODS:Patient data were obtained from medical records from the University Hospital "Príncipe de Asturias," Alcalá de He...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000009619
更新日期:2020-08-04 00:00:00
abstract::Twenty-two patients were analyzed 2 or more years after corpus callosum section (9 partial, 13 total). Forty-one percent had class 1 outcome (elimination of secondarily generalized and complex partial seizures), 32% had class 2 outcome (elimination of secondarily generalized seizures), and 27% had class 3 outcome (no ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.1.19
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:The present retrospective cohort study compares the long-term functional outcome, improvement or deterioration, of patients considered in a vegetative state (VS) or a minimally conscious state (MCS) 1 year after coma onset, then yearly for up to 5 years. METHODS:We reviewed the clinical courses of 12 patient...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181e8e8df
更新日期:2010-07-20 00:00:00
abstract:BACKGROUND:Treatment with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitors ("statins") has been associated in some epidemiologic studies with reduced risk of Alzheimer disease (AD). However, direct evidence of statin effects on neuropathologic markers of AD is lacking. We investigated whether antecedent stati...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000277657.95487.1c
更新日期:2007-08-28 00:00:00
abstract::Surgery is a safe and effective treatment for patients with temporal lobe epilepsy (TLE) who do not respond adequately to anticonvulsant medication and in whom the seizure generator can be identified and safely removed. Proton MR spectroscopic imaging (MRSI) can image and quantify neuronal damage in patients with TLE ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.49.6.1525
更新日期:1997-12-01 00:00:00
abstract::The intracarotid amobarbital test (IAT) examines hemispheric memory and language. We set out to determine whether memory performance on the IAT correlated with seizure relief after anterior temporal lobectomy in 117 patients with refractory epilepsy. The IAT assessed recognition memory performance for nine items with ...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.44.12.2325
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:To study activin signaling and its blockade in sporadic inclusion body myositis (sIBM) through translational studies and a randomized controlled trial. METHODS:We measured transforming growth factor β signaling by SMAD2/3 phosphorylation in muscle biopsies of 50 patients with neuromuscular disease (17 with s...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/WNL.0000000000001070
更新日期:2014-12-09 00:00:00
abstract::We studied the effect of CSF drainage on cerebral blood flow (CBF) in normal pressure hydrocephalus (NPH) and non-NPH dementia using the 133Xenon inhalation technique. Dementia patients had lower CBF than matched elderly normals. Flow values for NPH and non-NPH patients did not differ before or after CSF drainage. CBF...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.34.1.96
更新日期:1984-01-01 00:00:00
abstract::A 61-year-old woman presented with two paraneoplastic neurologic disorders--Lambert-Eaton myasthenic syndrome (LEMS) and subacute cerebellar degeneration (SCD)--that antedated the diagnosis of small-cell carcinoma of the lung by 15 months. Plasmapheresis initiated before the identification of the tumor had a beneficia...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.41.10.1682
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Antiretroviral therapy has improved survival for HIV-1-infected individuals. The neuroepidemiologic implications of HIV-1 in an aging population are not well known, particularly the prevalence of HIV-associated dementia (HAD). METHODS:The authors report a baseline cross-sectional analysis of 202 HIV-1-serop...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000134665.58343.8d
更新日期:2004-09-14 00:00:00
abstract:OBJECTIVE:The aim of this study was to apply the HIV-associated neurocognitive disorders (HAND) criteria for diagnosing HAND in HIV-infected adults, in a cohort of HIV-infected youth to thus establish whether this system is able to detect a spectrum of neurocognitive disorders (ND) in HIV-infected youth. METHODS:We us...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000002669
更新日期:2016-07-05 00:00:00
abstract::Two cases of giant-cell arteritis with cerebral arteritis are presented. The clinical situation and the suggestive but nonspecific angiographic features make the antemortem diagnosis possible. Greater awareness of this entity will facilitate its diagnosis and the institution of effective steroid therapy. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.27.8.794
更新日期:1977-08-01 00:00:00
abstract::MRI and CSF investigations revealed meningeal involvement in a 29-year-old patient with biopsy-confirmed Wegener's granulomatosis. The intracranial manifestation of Wegener's granulomatosis was supported by the detection of pathologic circulating antineutrophil cytoplasm (c-ANCA) in the CSF. We monitored disease activ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.1.263
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To determine age- and sex-specific AD prevalence rates for whites using each of four severity-based definitions of a case: a person diagnosed as having at least questionable AD, one diagnosed as having at least mild AD, one diagnosed as having moderate or severe AD, and one diagnosed as having severe AD. MET...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.55.2.198
更新日期:2000-07-25 00:00:00
abstract::The authors found serum immunoglobulin M (IgM) autoantibody in a patient with typical acute cerebellar ataxia (ACA) and identified the antigen molecule as triosephosphate isomerase (TPI). TPI antigenicity to the patient's antibody was the highest in the cerebellar tissue. Eight of 23 patients with ACA had increased Ig...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000178802.38268.1e
更新日期:2005-10-11 00:00:00
abstract::The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000219761.05466.43
更新日期:2006-06-27 00:00:00
abstract:OBJECTIVE:To present the current terminology and natural history of neurofibromatosis 1 (NF1) cutaneous neurofibromas (cNF). METHODS:NF1 experts from various research and clinical backgrounds reviewed the terms currently in use for cNF as well as the clinical, histologic, and radiographic features of these tumors usin...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000005792
更新日期:2018-07-10 00:00:00
abstract::PET-demonstrated decreases in [11C]flumazenil binding occur in anterior mesial temporal structures on the side of epileptogenesis in unilateral mesial temporal lobe epilepsy. We performed quantitative autoradiography on anterior mesial and lateral temporal specimens from 11 subjects with unilateral mesial temporal lob...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.5.934
更新日期:1995-05-01 00:00:00