Abstract:
:The authors used PET to show that the abnormal pattern of cerebral blood flow (CBF) activation described in PD is normalized by electrical stimulation of subthalamic nucleus. Improvement in bradykinesia correlated with increase in CBF due to stimulation in the supplementary motor area and anterior cingulate cortex. Compared to unilateral stimulation, bilateral stimulation induced a greater extent of activation in bilateral cortical areas and additional bilateral activation of globus pallidus.
journal_name
Neurologyjournal_title
Neurologyauthors
Strafella AP,Dagher A,Sadikot AFdoi
10.1212/01.wnl.0000052691.48076.92subject
Has Abstractpub_date
2003-03-25 00:00:00pages
1039-42issue
6eissn
0028-3878issn
1526-632Xjournal_volume
60pub_type
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