Abstract:
:The authors describe a patient with bilateral papilledema, visual field abnormalities, poorly reactive pupils, meningeal enhancement on cranial MRI, and diffuse brain parenchymal hypervascularity. The opening pressure at the time of lumbar puncture was normal, and results of other CSF studies were normal. All abnormalities resolved with home oxygen therapy.
journal_name
Neurologyjournal_title
Neurologyauthors
O'Halloran HS,Berger JR,Baker RS,Lee WB,Pearson PA,Ryan Sdoi
10.1212/wnl.53.9.2204subject
Has Abstractpub_date
1999-12-10 00:00:00pages
2204-5issue
9eissn
0028-3878issn
1526-632Xjournal_volume
53pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract:OBJECTIVE:To model the temporal trajectory of β-amyloid accumulation using serial amyloid PET imaging. METHODS:Participants, aged 70-92 years, were enrolled in either the Mayo Clinic Study of Aging (n = 246) or the Mayo Alzheimer's Disease Research Center (n = 14). All underwent 2 or more serial amyloid PET examinatio...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3182840bbe
更新日期:2013-03-05 00:00:00
abstract::We studied the effect of a single oral intake of 30 to 40 grams of alcohol in 4 consecutive patients presenting with Ramsay Hunt syndrome, the most common type of degenerative progressive myoclonic epilepsy (PME) encountered in southern Europe. Clinical and polygraphic monitoring demonstrated abatement of myoclonus in...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.40.9.1412
更新日期:1990-09-01 00:00:00
abstract::We studied the effects of bromocriptine on periodic limb movements in sleep (PLMS) of narcoleptic patients. Bromocriptine significantly reduced the number and index of PLMS without improving the nocturnal sleep disruption in that disorder. These results support the hypothesis that dopaminergic mechanisms are involved ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.10.2134
更新日期:1993-10-01 00:00:00
abstract:OBJECTIVE:To assess the natural progression of muscle weakness in spinal muscular atrophy (SMA) IIIb. METHODS:Ten patients with SMA IIIb were followed for at least 10 years. Age at disease onset varied between 9 and 18 years. Patients were initially seen 2 to 10 years after disease onset. They were evaluated at approx...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000324623.89105.c4
更新日期:2008-08-26 00:00:00
abstract::We studied 60 patients with idiopathic Parkinson disease with motor and neuropsychologic tests to ascertain whether the severity of motor symptoms was associated with the degree of neuropsychologic deficity. Significant correlations were found between the severity of brady kinesia and impaired performance on tests ass...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.32.2.133
更新日期:1982-02-01 00:00:00
abstract::The frequency, patterns of inheritance and clinical phenotypes of inherited myopathies with histologic features of rimmed vacuoles, tubulofilamentous inclusions and absence of inflammation (familial and hereditary inclusion body myopathy [f-IBM]) are poorly defined. Quadriceps sparing is a characteristic of f-IBM seen...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.47.4.977
更新日期:1996-10-01 00:00:00
abstract::Six members of a family had a neurologic disease with autosomal dominant transmission and adolescent onset of progressive wasting of predominantly distal axial muscles and muscles innervated by cranial nerves V, VII, X, and XII, leading to severe morbidity in adulthood. Muscle biopsy of the propositus revealed "ragged...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.26.8.754
更新日期:1976-08-01 00:00:00
abstract:OBJECTIVE:To study the association of PD with preceding smoking, alcohol, and coffee consumption using a case-control design. METHODS:The authors used the medical records linkage system of the Rochester Epidemiology Project to identify 196 subjects who developed PD in Olmsted County, MN, during the years 1976 to 1995....
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.55.9.1350
更新日期:2000-11-14 00:00:00
abstract::Proteins from single frozen sections of human muscle were separated by two-dimensional gel electrophoresis and detected by fluorography or Coomassie Blue staining. The major proteins were identical in different normal muscles obtained from either sex at different ages, and in Duchenne and myotonic dystrophy samples. C...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.33.9.1152
更新日期:1983-09-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of spinocerebellar ataxia (SCA) types 1, 2, 3, 6, and 7 and Friedreich's ataxia (FA) among a large panel of ataxia families. BACKGROUND:The ataxias are a clinically and genetically heterogeneous group of neurodegenerative diseases that variably affect the cerebellum, brainstem, and...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.51.6.1666
更新日期:1998-12-01 00:00:00
abstract::Our understanding of the pathogenesis of Alzheimer's disease (AD) had advanced rapidly, particularly in the area of genetics. Clinical trials of agents that offer the promise of going beyond symptomatic treatment to actually slowing the progression of disease, perhaps by enhancing the viability of neurons, are under w...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.48.5_suppl_7.2s
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVE:We used transcranial magnetic stimulation to investigate the effect of diurnal variability on cortical excitability in patients with epilepsy. METHODS:Thirty drug-naive patients with epilepsy (20 idiopathic generalized epilepsy [IGE], including 10 juvenile myoclonic epilepsy [JME], and 10 focal epilepsy) and...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181ae7ca6
更新日期:2009-07-21 00:00:00
abstract::We conducted a randomized double-blind comparison of three doses of the novel antiepileptic drug (AED) topiramate (200, 400, and 600 mg/day) and placebo as adjunctive therapy in patients with refractory partial onset epilepsy receiving one or two other AEDs at therapeutic concentrations. A total of 181 patients comple...
journal_title:Neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1212/wnl.46.6.1684
更新日期:1996-06-01 00:00:00
abstract::Migraine is a frequent familial disorder that, in common with most multifactorial disorders, has an unknown etiology. The authors identified several families with multiple individuals affected by typical migraine using a single set of diagnostic criteria and studied these families for cosegregation between the disorde...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.5.1428
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To determine the role of weight loss in the treatment of idiopathic intracranial hypertension (IIH) in obese women. METHODS:Chart review of 250 patients with suspected IIH revealed 58 women who met our criteria, did not undergo early surgical intervention, and had adequate documentation of visual status, pap...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.4.1094
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Because of the relatively poor results of frontal lobe epilepsy (FLE) surgery, identification of prognostic factors for surgical outcome is of great importance. METHODS:To identify predictive factors for FLE surgery, we analyzed the data of 61 patients (mean age at surgery 19.2) who had undergone presurgica...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.54.7.1470
更新日期:2000-04-11 00:00:00
abstract::Immitation synkinesia is usually associated with thalamic or parietal lesions. Analysis of three cases shows that the lesions may affect the posterior columns of the spinal cord or even the peripheral nervous system. In our cases, two facts stand out, a large measure of integrity of motor activity and predominant dist...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.27.7.646
更新日期:1977-07-01 00:00:00
abstract::We administered Ro 40-7592, an inhibitor of the enzyme catechol-O-methyltransferase (COMT) that crosses the blood-brain barrier, to rats and monitored extracellular catecholamine levels in the corpus striatum before and after the intraperitoneal administration of a bolus of l-dopa. Acute administration of Ro 40-7592 i...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.3.683
更新日期:1992-03-01 00:00:00
abstract:OBJECTIVE:We aimed to analyze lesion patterns of lacunae-sized infarctions in the perforating arterial territory in terms of shape and to determine whether the particular pattern of conglomerated beads shape affected early neurologic deterioration. METHODS:We consecutively included acute ischemic stroke patients with ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e318253d62f
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To assess the genetic contribution of TBK1, a gene implicated in amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and FTD-ALS, in Belgian FTD and ALS patient cohorts containing a significant part of genetically unresolved patients. METHODS:We sequenced TBK1 in a hospital-based cohort of 48...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000002220
更新日期:2015-12-15 00:00:00
abstract::Epilepsia partialis continua (EPC) may occur during nonketotic hyperglycemia but has not been described with diabetic ketoacidosis. The authors report a patient with EPC associated with ketotic hyperglycemia. Brain MRI showed two areas of abnormal signal intensity in the left precentral gyrus and in the right cerebell...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.3.534
更新日期:2001-08-14 00:00:00
abstract::Neurologic complications of brain tissue-derived rabies vaccine may be chronic or progressive. Lymphocytes and serum from three patients with this form of encephalitis were studied. Two patients had positive lymphoproliferation to purified myelin, two had antibody to white matter, and one had antibody to myelin basic ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.1.42
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:Learning and memory impairments are prevalent among persons with multiple sclerosis (MS); however, such deficits are only weakly associated with MS disease severity (brain atrophy). The cognitive reserve hypothesis states that greater lifetime intellectual enrichment lessens the negative impact of brain disea...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181e396be
更新日期:2010-06-15 00:00:00
abstract::Endovascular therapy for acute ischemic stroke continues to evolve to improve both efficacy and safety. In the late 1990 s, intra-arterial chemical thrombolysis with prourokinase was shown to be effective in achieving partial recanalization and improving clinical outcome, in comparison with intra-arterial heparin admi...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0b013e3182697e9e
更新日期:2012-09-25 00:00:00
abstract::Data from three patients and 22 previously reported cases suggest that cerebral microinfarction causes a recognizable clinical syndrome. All cases present with stroke, followed by progressive dementia and often with visual field deficits, peripheral vascular disease, and signs of motor neuron dysfunction. The average ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.35.6.789
更新日期:1985-06-01 00:00:00
abstract::A 57-year-old chronically immunosuppressed woman with systemic lupus erythematosus developed fulminant meningoencephalitis due to Acanthamoeba castellanii. Amebic trophozoites were also found in the lungs, suggesting a primary pulmonary focus of infection. This case illustrates that Acanthamoeba can cause a fulminant,...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.31.2.174
更新日期:1981-02-01 00:00:00
abstract::Effective diagnosis and treatment of cytomegalovirus infection of the nervous system in AIDS patients has been limited by a lack of sensitive diagnostic measures. Retrospective series suggest a poor prognosis for cytomegalovirus encephalitis with rapid mortality. Polymerase chain reaction amplification of cytomegalovi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.46.2.444
更新日期:1996-02-01 00:00:00
abstract::The authors report eight patients with primary dural lymphoma (PDL). All patients had extra-axial masses on MRI that diffusely enhanced after gadolinium. Pathology revealed low-grade non-Hodgkin lymphoma (marginal zone lymphoma of MALT [mucosa-associated lymphoid tissue] type) in all patients. All patients underwent r...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000218284.23872.eb
更新日期:2006-06-13 00:00:00
abstract:OBJECTIVE:To estimate the prevalence and examine the course of mild cognitive impairment (MCI), amnestic type, using current criteria, within a representative community sample. METHODS:Retroactive application of MCI criteria to data collected during a prospective epidemiologic study was performed. The subjects were dr...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000132523.27540.81
更新日期:2004-07-13 00:00:00
abstract:OBJECTIVES:Intracerebral hemorrhage (ICH) is a highly lethal disease of the elderly. Use of statins is increasingly widespread among the elderly, and therefore common in patients who develop ICH. Accumulating data suggests that statins have neuroprotective effects, but their association with ICH outcome has been incons...
journal_title:Neurology
pub_type: 杂志文章,meta分析
doi:10.1212/WNL.0b013e3182194be9
更新日期:2011-05-03 00:00:00