Abstract:
:Immitation synkinesia is usually associated with thalamic or parietal lesions. Analysis of three cases shows that the lesions may affect the posterior columns of the spinal cord or even the peripheral nervous system. In our cases, two facts stand out, a large measure of integrity of motor activity and predominant disturbances of lemniscal sensation. Imitation synkinesia should therefore not be seen as due to a lesion of a particular structure but to the disorganization of the lemniscal system at any level. Functional interconnection between the lemniscal and motor systems occurs only in the cerebral cortex. In the light of this fact, imitation synkinesia can be interpreted as the loss of particular functions in the principal cortical motor neurons.
journal_name
Neurologyjournal_title
Neurologyauthors
Cambier J,Dehen Hdoi
10.1212/wnl.27.7.646subject
Has Abstractpub_date
1977-07-01 00:00:00pages
646-9issue
7eissn
0028-3878issn
1526-632Xjournal_volume
27pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::We report the cases of three siblings homozygous for a mutated transthyretin (TTR) gene that causes type I familial amyloidotic polyneuropathy (FAP), in whom we made the diagnosis by identifying both the mutated TTR gene and a variant TTR in their sera. Their serum levels for the variant TTR are twice those of patient...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.10.2045
更新日期:1992-10-01 00:00:00
abstract::Recurrent episodes of oscillopsia, rotational vertigo, and postural imbalance were elicited and modulated by changing the horizontal head positions of a patient with an arachnoid cyst in the right cerebellopontine angle that distorted the vestibulocochlear nerve. Oculomotor analysis revealed two different types of att...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.51.5.1480
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:Diagnostic criteria from 2002 classify transverse myelitis (TM) as idiopathic or disease associated but predate the discovery of aquaporin-4 (AQP4)-immunoglobulin G (IgG) and myelin oligodendrocyte glycoprotein (MOG)-IgG, which associate with TM. Prior incidence estimates of idiopathic TM (ITM) range from 1 t...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000007828
更新日期:2019-07-23 00:00:00
abstract:OBJECTIVE:To assess the relationship between CSF creatine kinase BB isoenzyme activity (CSF CKBB) and neurologic outcome after cardiac arrest in clinical practice. BACKGROUND:CSF CKBB reflects the extent of brain damage following cardiac arrest. METHODS:To help with prognosis, treating physicians ordered CSF CKBB tes...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.2.352
更新日期:1997-02-01 00:00:00
abstract::Lymphocytic meningoradiculitis (Bannwarth's syndrome) is a radicular neuralgia associated with a chronic lymphocytic pleocytosis in cerebrospinal fluid and frequently with unilateral or bilateral peripheral facial weakness. Most reported cases have occurred during the summer among adults living in central Europe. Lymp...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.33.11.1476
更新日期:1983-11-01 00:00:00
abstract:OBJECTIVE:Causes of benign positional vertigo (BPV) are mostly unknown. The aim of this study was to elucidate an association of osteoporosis with idiopathic BPV. METHODS:Two hundred nine consecutive patients with a confirmed diagnosis of idiopathic BPV underwent bone mineral densitometry of anterior-posterior lumbar ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000345016.33983.e0
更新日期:2009-03-24 00:00:00
abstract:OBJECTIVE:To classify neuropathologic alterations in the brains of nondemented older adults using current sets of criteria for AD. BACKGROUND:AD neuropathologic alterations are found in the brains of some nondemented elderly subjects and suggest the possibility of presymptomatic AD. Three sets of guidelines have been ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.55.3.370
更新日期:2000-08-08 00:00:00
abstract::We review adjunctive ketogenic diet (KD) and modified Atkins diet (MAD) treatment of refractory epilepsy in adults. Only a few studies have been published, all open-label. Because of the disparate, uncontrolled nature of the studies, we analyzed all studies individually, without a meta-analysis. Across all studies, 32...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0000000000001004
更新日期:2014-11-18 00:00:00
abstract::We performed a retrospective study on a series of 119 of our patients who have Friedreich's disease to assess the predictive value of age at onset, gender, and left ventricular hypertrophy in regard to disease progression. Outcome variables were survival, time to loss of independent gait, and time to confinement in a ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.47.5.1260
更新日期:1996-11-01 00:00:00
abstract::An allele (263bp) of the nonamyloid component of plaques (NACP)-Repl polymorphism has shown association with sporadic PD in a German population. The authors studied this polymorphism in 100 American PD patients and 100 healthy controls. The authors also studied 46 essential tremor (ET) and 55 Huntington's disease (HD)...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.54.5.1195
更新日期:2000-03-14 00:00:00
abstract::We found an antinuclear antibody highly restricted to nuclei of neurons in two patients with subacute sensory neuronopathy complicating oat cell carcinoma of the lung. Serum was tested by indirect immunofluorescence and immunoperoxidase staining. At low concentrations of antibody, only the nuclei of the neurons were s...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.35.4.538
更新日期:1985-04-01 00:00:00
abstract:OBJECTIVE:To apply multisequence MRI techniques to patients with clinically isolated syndromes, to document the pattern and frequency of abnormalities at baseline and early follow-up, and to determine their predictive values for the early development of clinical MS. BACKGROUND:Disseminated lesions on T2-weighted brain...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.53.6.1184
更新日期:1999-10-12 00:00:00
abstract:OBJECTIVE:In families with autosomal dominant partial epilepsy with auditory features (ADPEAF) with mutations in the LGI1 gene, we evaluated clustering of mutations within the gene and associations of penetrance and phenotypic features with mutation location and predicted effect (truncation or missense). METHODS:We ab...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e318247ccbf
更新日期:2012-02-21 00:00:00
abstract:OBJECTIVES:(1) To assess the diagnostic accuracy of EMG in radiculopathy. (2) To evaluate the intrarater reliability and interrater reliability of EMG in radiculopathy. (3) To assess the presence of confirmation bias in EMG. METHODS:Three experienced academic electromyographers interpreted 3 compact discs with 20 EMG ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000002292
更新日期:2016-01-19 00:00:00
abstract:OBJECTIVE:To report our experience delivering intrathecal nusinersen through cervical puncture in patients with spinal muscular atrophy (SMA) with no lumbar access. BACKGROUND:SMA is a neuromuscular disorder characterized by profound muscle weakness, atrophy, and paralysis due to degeneration of the anterior horn cell...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006006
更新日期:2018-08-14 00:00:00
abstract:OBJECTIVE:To evaluate the relationship of white matter hyperintensities (WMH) with decline in lower extremity function (LEF) over approximately 3 years in dementia-free older adults with memory complaints. METHODS:We obtained brain MRI data from 458 community-dwelling adults, aged 70 years or over, at baseline, and fr...
journal_title:Neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1212/WNL.0000000000005289
更新日期:2018-04-10 00:00:00
abstract:OBJECTIVE:To determine whether, and to what degree, preclinical Alzheimer disease (AD) confounds studies of healthy aging where "healthy" is based on cognitive normality alone. METHODS:We examined the effects of preclinical AD in cognitively normal older individuals using resting-state functional connectivity MRI. We ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000000939
更新日期:2014-10-28 00:00:00
abstract::A new generation of Atraumatic (blunt tipped) needles now exists in addition to the traditional Quincke (cutting tip) needles for LP. We wished to identify the optimal size and type of needle that should be used for this technique. Requirements include rapid and accurate transduction of CSF pressure and adequate flow ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.47.1.33
更新日期:1996-07-01 00:00:00
abstract::The incidence of MS in the Orkney Islands has been updated from 1941 to September 21, 1983. Since 1965, MS incidence rates have fallen significantly when compared with those for 1941 to 1964. Alterations in age-specific prevalence, mean duration of illness, and mean age of the MS population are consistent with the dec...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.35.4.545
更新日期:1985-04-01 00:00:00
abstract::The authors identified two novel heterozygous missense transitions in the gene for the mitochondrial polymerase gammaA subunit (POLG) in a family with an autosomal recessive syndrome comprising progressive external ophthalmoplegia (PEO), polyneuropathy, ataxia, sensorineural hearing loss, and affective disorders. Thes...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.62.2.316
更新日期:2004-01-27 00:00:00
abstract:OBJECTIVE:Optical coherence tomography (OCT) noninvasively quantifies retinal nerve fiber layer (RNFL) thickness. Studies show RNFL thinning in multiple sclerosis (MS), and we assessed its association with brain atrophy. METHODS:RNFL thickness was measured in 40 patients with MS and 15 controls. Brain parenchymal frac...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000295995.46586.ae
更新日期:2007-10-16 00:00:00
abstract::Arm-diaphragm synkinesis may occur after injury to the proximal portion of the brachial plexus or cervical nerve roots. Regenerating axons of phrenic motor neurons are misdirected to supply limb muscles. Electrodiagnostic investigations of three patients with symptoms referable to upper brachial plexus or cervical roo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.30.4.339
更新日期:1980-04-01 00:00:00
abstract::Proximal myotonic myopathy (PROMM) is an autosomal dominantly inherited multisystemic disorder characterized by myotonia, proximal muscle weakness, and cataracts. This disorder is not linked to the gene locus of myotonic dystrophy (DM). We describe three new families with PROMM. In all patients, CTG repeats of the DM ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.1.33
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:Prospective memory (PM) describes the ability to fulfill previously planned intentions and is highly dependent on executive functions. Previous studies have shown deficits in executive functions in patients with juvenile myoclonic epilepsy (JME) and in their unaffected siblings. JME has a strong genetic predi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e318202010a
更新日期:2010-12-14 00:00:00
abstract:OBJECTIVE:To assess the effects of levodopa on resting-state brain metabolism in PD. BACKGROUND:In previous studies the authors used [18F] fluorodeoxyglucose (FDG) and PET to quantify regional metabolic abnormalities in PD. They found that this disease is characterized reproducibly by a specific abnormal PD-related pa...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.11.2083
更新日期:2001-12-11 00:00:00
abstract::The authors studied the tolerability of subcutaneous interferon beta-1a (IFNbeta-1a) in 51 patients with early-onset multiple sclerosis. The most frequent systemic adverse effects were flu-like symptoms in 65%. Laboratory abnormalities included asymptomatic leukopenia (27%) and elevated hepatic transaminases (35%). Tr...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000153570.33845.6A
更新日期:2005-03-08 00:00:00
abstract::We studied the effects of botulinum toxin A in 12 patients with spasticity and in eight patients with rigidity. The study design was a double-blind, placebo-controlled crossover trial with botulinum toxin A versus saline. Using the Ashworth Scale for spasticity and the Unified Parkinson's Disease Rating Scale for rigi...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.45.4.712
更新日期:1995-04-01 00:00:00
abstract::Restless legs syndrome (RLS) is a common neurologic disorder whose prevalence has been estimated at 4 to 10% of the general population. Although its pathophysiology remains unknown, dopaminergic mechanisms are believed to play a central role. Furthermore, dopaminergic drugs have shown therapeutic efficacy in various l...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.61.6_suppl_3.s49
更新日期:2003-09-23 00:00:00
abstract::A patient with thymoma-associated neuromyotonia and voltage-gated potassium channel (Kv1.2 and Kv1.6) antibodies by immunoprecipitation and rat brain immunolabeling was treated successfully with immunoadsorption and cyclophosphamide. Curiously, glutamic acid decarboxylase antibodies, absent at onset, appeared later. S...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000156945.39471.2C
更新日期:2005-04-12 00:00:00
abstract::We determined the horizontal and vertical components of brain displacement on coronal MRIs in 10 patients with acute supratentorial masses. The vertical distances from the superior sagittal sinus to the pontomesencephalic junction (PMJ) and from the vertical midline of the brain to the PMJ did not differ from measurem...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.39.5.622
更新日期:1989-05-01 00:00:00