Conglomerated beads shape of lacunar infarcts on diffusion-weighted MRI: what does it suggest?

abstract：:Epilepsy surgery is a well-established treatment for certain types of intractable epilepsy. While there is a relatively high number of epilepsy surgery centers in Canada and the United States, the same cannot be said about many other parts of the world, such as South America. Although there are notable exceptions, suc...

journal_title：Neurology

authors： Steven DA,Vasquez CM,Delgado JC,Zapata-Luyo W,Becerra A,Barreto E,Arango MF,Burneo JG

更新日期：2018-08-21 00:00:00

abstract：:We have studied one family of a pedigree in which bulbospinal muscular atrophy and protanopia were segregated. Genotypes for these disorders were obtained on three generations, and the maximum likelihood estimate of recombination fraction was 0.4 with the lod score method. The results indicated that the two loci are n...

journal_title：Neurology

authors： Mukai E,Yasuma T

更新日期：1987-06-01 00:00:00

abstract：:Recently published reports have suggested that multiple sclerosis (MS) may be associated with human retrovirus infection. Indeed, an autonomously proliferating T-cell clone was isolated from the CSF of an MS patient, an observation interpreted as indicating an infection with human T lymphotropic virus I (HTLV I). In v...

journal_title：Neurology

authors： Birnbaum G,Aubitz S,Kotilinek L

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To describe a kindred with a dominantly inherited neurologic disorder manifested either as uncomplicated spastic paraplegia or ataxia, spastic paraplegia, and mental retardation. METHODS:Neurologic examinations and molecular genetic analysis (exclusion of known SCA and HSP genes and loci; and trinucleotide r...

journal_title：Neurology

authors： Hedera P,Rainier S,Zhao XP,Schalling M,Lindblad K,Yuan QP,Ikeuchi T,Trobe J,Wald JJ,Eldevik OP,Kluin K,Fink JK

更新日期：2002-02-12 00:00:00

abstract：:Anti-Leu 7 antibody reacts with determinants on a subset of natural killer (NK) cells and myelin-associated glycoprotein (MAG). In a patient patient with peripheral neuropathy and IgM autoantibodies against MAG, we found the distribution and functions of NK cells to be normal. ...

journal_title：Neurology

authors： Sriram S,Lanier L

更新日期：1986-04-01 00:00:00

abstract：:Proteins from single frozen sections of human muscle were separated by two-dimensional gel electrophoresis and detected by fluorography or Coomassie Blue staining. The major proteins were identical in different normal muscles obtained from either sex at different ages, and in Duchenne and myotonic dystrophy samples. C...

journal_title：Neurology

authors： Giometti CS,Danon MJ,Anderson NG

更新日期：1983-09-01 00:00:00

abstract：:Long-term hypothalamic stimulation is effective in improving drug-resistant chronic cluster headache (CH). We assessed acute hypothalamic stimulation to resolve ongoing CH attacks in 16 patients implanted to prevent chronic CH, investigating 136 attacks. A pain intensity reduction of > or =50% occurred in 25 of 108 ev...

journal_title：Neurology

authors： Leone M,Franzini A,Broggi G,Mea E,Cecchini AP,Bussone G

更新日期：2006-11-28 00:00:00

abstract：:The intensive study of seizures via serial 24-hour EEG-video monitoring has allowed enhanced observation of sleep patterns among epilepsy patients and has revealed that disturbed rest is common in this population. Previous work has shown that sleep deprivation of any type can exacerbate seizure activity, leading to sp...

journal_title：Neurology

authors： Sammaritano M,Sherwin A

更新日期：2000-01-01 00:00:00

abstract：:Comprehensive management of patients with multiple sclerosis (MS) includes treatment to modify the disease course and interventions to address the persistent symptoms and consequences of this chronic illness, which can affect patients for decades. Although much excitement and attention accompanies new therapeutic init...

journal_title：Neurology

authors： Cohen BA

更新日期：2008-12-09 00:00:00

abstract：OBJECTIVE:To investigate the relationship between the presence of a circadian body temperature rhythm and behaviorally assessed consciousness levels in patients with disorders of consciousness (DOC; i.e., vegetative state/unresponsive wakefulness syndrome or minimally conscious state). METHODS:In a cross-sectional stu...

journal_title：Neurology

authors： Blume C,Lechinger J,Santhi N,del Giudice R,Gnjezda MT,Pichler G,Scarpatetti M,Donis J,Michitsch G,Schabus M

更新日期：2017-05-16 00:00:00

abstract：OBJECTIVE:To determine the relationship between neurology inpatient satisfaction and (1) number of physicians involved in the patient's care and (2) patients' ability to identify their physicians. METHODS:A 10-item questionnaire addressing patient satisfaction and identification of physicians on the care team was admi...

journal_title：Neurology

authors： Leon Guerrero CR,Anderson T,Zazulia AR

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Clostridium botulinum neurotoxin types A, B, and E cause most cases of the paralytic disease botulism. Little is known about the epidemiology, clinical features, or microbiology of botulism type F. METHODS:Cases of adult type F botulism were identified by review of data collected by CDC's National Botulism ...

journal_title：Neurology

authors： Gupta A,Sumner CJ,Castor M,Maslanka S,Sobel J

更新日期：2005-12-13 00:00:00

abstract：:Three neuropathologists evaluated brain sections from 43 aged subjects for the presence of Alzheimer's disease. Moderate-to-substantial agreement was obtained. After discussion of disparate diagnoses, agreement was almost perfect for standardized and substantial for personal criteria. We conclude that reproducibility ...

journal_title：Neurology

authors： Paulus W,Bancher C,Jellinger K

更新日期：1992-02-01 00:00:00

abstract：:Antiepileptic drug use was documented before and after temporal lobectomy. Carbamazepine, phenytoin, and clobazam were the most commonly used drugs, both pre- and postoperatively. Preoperatively, polytherapy was used in 78% of patients; at 6 months follow-up, 47%; at 12 months, 18%; and at 24 months, 14%. Preoperative...

journal_title：Neurology

authors： Maher J,McLachlan RS

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:The annual relapse rate has been commonly used as a primary efficacy endpoint in phase III multiple sclerosis (MS) clinical trials. The aim of this study was to determine the relative contribution of different possible prognostic factors available at baseline to the on-study relapse rate in MS. METHODS:A to...

journal_title：Neurology

authors： Held U,Heigenhauser L,Shang C,Kappos L,Polman C,Sylvia Lawry Centre for MS Research.

更新日期：2005-12-13 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Collagen abnormalities of skin have been reported among patients with ALS. However, little is known concerning glycosaminoglycans of the skin in ALS. Our objective was to clarify morphologic and biochemical findings of skin glycosaminoglycans among patients with ALS. METHODS:We performed morph...

journal_title：Neurology

authors： Ono S,Imai T,Aso A,Yamano T,Shimizu N,Nagao K

更新日期：1998-08-01 00:00:00

abstract：:We report a patient with meningeal gliomatosis who had signs of meningitis, hypoglycorrhachia, and an intracranial mass. Despite suspicion of a primary intracranial neoplasm, repeated CSF cytologies were not diagnostic and led to a brain biopsy for diagnosis. Immunoperoxidase staining for glial fibrillary acidic prote...

journal_title：Neurology

authors： Wechsler LR,Gross RA,Miller DC

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:We developed the Recurrence and Recovery Questionnaire (RRQ) by converting the Pediatric Stroke Outcome Measure (PSOM) to a questionnaire for telephone interview and sought to validate the RRQ in a large cohort. METHOD:We analyzed parents' RRQ responses and same-day PSOM assessments for 232 children who had ...

journal_title：Neurology

authors： Lo WD,Ichord RN,Dowling MM,Rafay M,Templeton J,Halperin A,Smith SE,Licht DJ,Moharir M,Askalan R,Deveber G,International Pediatric Stroke Study (IPSS) Investigators.

更新日期：2012-08-28 00:00:00

abstract：:Treatment of functional symptoms has a long history, and interventions were often used in soldiers returning from battle. On the 75th anniversary of the end of the Second World War, I review the portrayal of neurology in documentary film. Two documentaries were released in 1946 and 1948 (Let There Be Light and Shades ...

journal_title：Neurology

authors： Wijdicks EFM

更新日期：2020-06-09 00:00:00

abstract：OBJECTIVE:To examine associations of orthostatic hypotension (OH) with dementia and long-term cognitive decline and to update previously published results in the same cohort for stroke with an additional 16 years of follow-up. METHODS:We analyzed data from 11,709 participants without a history of coronary heart diseas...

journal_title：Neurology

authors： Rawlings AM,Juraschek SP,Heiss G,Hughes T,Meyer ML,Selvin E,Sharrett AR,Windham BG,Gottesman RF

更新日期：2018-08-21 00:00:00

abstract：:A case-control study was conducted on 64 cases of "probable Alzheimer's disease" with late onset of illness (after age 70 years) and 64 controls matched by age (+/- 3 years), race, and sex. Information was obtained on birth order, lifetime medical and surgical history, personal characteristics, exposure to toxins and ...

journal_title：Neurology

authors： Chandra V,Philipose V,Bell PA,Lazaroff A,Schoenberg BS

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:Utilization of postacute care is associated with improved poststroke outcomes. However, more than 20% of American adults under age 65 are uninsured. We sought to determine whether insurance status is associated with utilization and intensity of institutional postacute care among working age stroke survivors. ...

journal_title：Neurology

authors： Skolarus LE,Meurer WJ,Burke JF,Prvu Bettger J,Lisabeth LD

更新日期：2012-05-15 00:00:00

abstract：:Intracranial EEG recording is often required to identify an area of the brain for resective surgery for intractable epilepsy. We simultaneously compared bilaterally placed depth and limited subdural electrode EEG to determine the most effective method of recording seizures from the temporal lobes. Localized complex pa...

journal_title：Neurology

authors： Sperling MR,O'Connor MJ

更新日期：1989-11-01 00:00:00

abstract：:We describe an atypical neurologic presentation of Wegener's granulomatosis (WG) with striking meningeal and cerebral involvement, responding to immunosuppressive therapy. WG may cause treatable intracranial complications in the absence of nasal or renal disease and without cerebral angiographic abnormalities, CSF ple...

journal_title：Neurology

authors： Weinberger LM,Cohen ML,Remler BF,Naheedy MH,Leigh RJ

更新日期：1993-09-01 00:00:00

abstract：:Heterozygous PAX6 mutation is associated with an absent or hypoplastic anterior commissure and a reduction in the area of the corpus callosum. The authors found deficient auditory interhemispheric transfer in a 53-year-old woman with a PAX6 mutation who had an absent anterior commissure but normal callosal volume. ...

journal_title：Neurology

authors： Bamiou DE,Musiek FE,Sisodiya SM,Free SL,Mitchell TN,Davies RA

更新日期：2004-02-10 00:00:00

abstract：OBJECTIVE:To investigate clinical differences in warm and cold complex regional pain syndrome (CRPS) phenotypes. BACKGROUND:CRPS represents inhomogeneous chronic pain conditions; approximately 70% patients with CRPS have "warm" affected limbs and 30% have "cold" affected limbs. METHODS:We examined 50 patients with "c...

journal_title：Neurology

authors： Eberle T,Doganci B,Krämer HH,Geber C,Fechir M,Magerl W,Birklein F

更新日期：2009-02-10 00:00:00

abstract：:In a 24-week, randomized, double-blind, placebo-controlled, multicenter study of rivastigmine, 487 patients with dementia associated with Parkinson disease underwent assessment of attention on the Cognitive Drug Research computerized cognitive assessment system before dosing and 16 and 24 weeks later. Significant bene...

journal_title：Neurology

authors： Wesnes KA,McKeith I,Edgar C,Emre M,Lane R

更新日期：2005-11-22 00:00:00

abstract：OBJECTIVE:To evaluate differences in cerebrovascular reactivity (CVR) to mild hypercapnia in obese/overweight individuals with and without insulin resistance (IR) compared to comparable lean controls. METHODS:A total of 60 cognitively normal participants (20 lean controls and 24 obese/overweight individuals with and 1...

journal_title：Neurology

authors： Frosch OH,Yau PL,Osorio RS,Rusinek H,Storey P,Convit A

更新日期：2017-07-18 00:00:00

abstract：BACKGROUND:Hereditary neuralgic amyotrophy (HNA) is an autosomal-dominant disorder associated with recurrent, episodic, painful, brachial neuropathy. The gene for HNA has been mapped to chromosome 17q25. Characteristic features including hypotelorism, short stature, and cleft palate occur in some patients. OBJECTIVE:T...

journal_title：Neurology

authors： Jeannet PY,Watts GD,Bird TD,Chance PF

更新日期：2001-12-11 00:00:00

abstract：OBJECTIVE:To determine whether pergolide, a mixed D1/D2/D3 dopamine agonist, is efficacious and safe in the treatment of children with chronic tic disorders and Tourette syndrome. BACKGROUND:Neuroleptics, which block dopamine transmission, are currently used to treat children with severe tics, but major side effects a...

journal_title：Neurology

authors： Gilbert DL,Dure L,Sethuraman G,Raab D,Lane J,Sallee FR

更新日期：2003-02-25 00:00:00