A pedigree with protanopia and bulbospinal muscular atrophy.

Abstract:

:We have studied one family of a pedigree in which bulbospinal muscular atrophy and protanopia were segregated. Genotypes for these disorders were obtained on three generations, and the maximum likelihood estimate of recombination fraction was 0.4 with the lod score method. The results indicated that the two loci are not close; the locus for bulbospinal muscular atrophy is not located near the end of the long arm of the X chromosome.

journal_name

Neurology

journal_title

Neurology

authors

Mukai E,Yasuma T

doi

10.1212/wnl.37.6.1019

subject

Has Abstract

pub_date

1987-06-01 00:00:00

pages

1019-21

issue

6

eissn

0028-3878

issn

1526-632X

journal_volume

37

pub_type

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