Hemiparkinsonism as a late complication of hemiatrophy: a new syndrome.

Abstract:

:Four men with evidence of hemiatrophy resulting from early-life hemispheral injury developed unilateral hemiparkinsonism on the side of the hemiatrophy. The parkinsonism began in the fourth decade and has remained unilateral for 5 to 35 years. In all four patients, the parkinsonism was slowly progressive, but the clinical response to levodopa was minimal, suggesting that the parkinsonism might have a postsynaptic striatal component. The clinical similarities of these four patients suggest that this is a distinct syndrome in which hemiparkinsonism is a late sequela of hemiatrophy. Identification of this syndrome has prognostic significance, because it seems to have a stereotyped course, remaining unilateral and only slowly progressive.

journal_name

Neurology

journal_title

Neurology

authors

Klawans HL

doi

10.1212/wnl.31.5.625

subject

Has Abstract

pub_date

1981-05-01 00:00:00

pages

625-8

issue

5

eissn

0028-3878

issn

1526-632X

journal_volume

31

pub_type

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