Practice variability in brain death determination: a call to action.

abstract：OBJECTIVE:To investigate long-term employment outcomes after resective epilepsy surgery in a national population-based cohort of adults. METHODS:In the Swedish National Epilepsy Surgery Register, all adults who were operated with resective epilepsy surgery from 1995 to 2010 were identified. Two-year follow-up was avai...

journal_title：Neurology

authors： Edelvik A,Flink R,Malmgren K

更新日期：2015-10-27 00:00:00

abstract：OBJECTIVE:To compare the proportion of APOE ε4 genotype carriers in aphasic vs amnestic variants of Alzheimer disease (AD). METHOD:The proportion of APOE ε4 carriers was compared among the following 3 groups: (1) 42 patients with primary progressive aphasia (PPA) and AD pathology (PPA/AD) enrolled in the Northwestern ...

journal_title：Neurology

authors： Weintraub S,Teylan M,Rader B,Chan KCG,Bollenbeck M,Kukull WA,Coventry C,Rogalski E,Bigio E,Mesulam MM

更新日期：2020-02-11 00:00:00

abstract：OBJECTIVE:The aim of this study was to apply the HIV-associated neurocognitive disorders (HAND) criteria for diagnosing HAND in HIV-infected adults, in a cohort of HIV-infected youth to thus establish whether this system is able to detect a spectrum of neurocognitive disorders (ND) in HIV-infected youth. METHODS:We us...

journal_title：Neurology

authors： Hoare J,Phillips N,Joska JA,Paul R,Donald KA,Stein DJ,Thomas KG

更新日期：2016-07-05 00:00:00

abstract：BACKGROUND:The antivirally active MxA protein is induced by interferon (IFN) alpha/beta and inhibits the replication of single-stranded RNA viruses including measles virus (MV). The authors investigated whether the MxA gene contributed to the development of subacute sclerosing panencephalitis (SSPE) in Japanese individ...

journal_title：Neurology

authors： Torisu H,Kusuhara K,Kira R,Bassuny WM,Sakai Y,Sanefuji M,Takemoto M,Hara T

更新日期：2004-02-10 00:00:00

abstract：OBJECTIVE:To determine whether exposure to repetitive head impacts over a single season negatively affects cognitive performance in collegiate contact sport athletes. METHODS:This is a prospective cohort study at 3 Division I National Collegiate Athletic Association athletic programs. Participants were 214 Division I ...

journal_title：Neurology

authors： McAllister TW,Flashman LA,Maerlender A,Greenwald RM,Beckwith JG,Tosteson TD,Crisco JJ,Brolinson PG,Duma SM,Duhaime AC,Grove MR,Turco JH

更新日期：2012-05-29 00:00:00

abstract：:We report a 51-year-old woman with vitamin B12 deficiency who presented with slight megaloblastic anemia and severe neurologic deficits associated with multiple focal and confluent T2-weighted white matter hyperintensities on brain MRI. Forty-four months after initiation of hydroxocobalamin therapy, there was clinical...

journal_title：Neurology

authors： Stojsavljević N,Lević Z,Drulović J,Dragutinović G

更新日期：1997-09-01 00:00:00

abstract：:We have identified large-scale deletions in muscle mitochondrial DNA (mtDNA) in seven of seven patients with Kearns-Sayre syndrome (KSS). We found no detectable deletions in the mtDNA of ten non-KSS patients with other mitochondrial myopathies or encephalomyopathies, or three normal controls. The deletions ranged in s...

journal_title：Neurology

authors： Zeviani M,Moraes CT,DiMauro S,Nakase H,Bonilla E,Schon EA,Rowland LP

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between CSF creatine kinase BB isoenzyme activity (CSF CKBB) and neurologic outcome after cardiac arrest in clinical practice. BACKGROUND:CSF CKBB reflects the extent of brain damage following cardiac arrest. METHODS:To help with prognosis, treating physicians ordered CSF CKBB tes...

journal_title：Neurology

authors： Tirschwell DL,Longstreth WT Jr,Rauch-Matthews ME,Chandler WL,Rothstein T,Wray L,Eng LJ,Fine J,Copass MK

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Although gray matter (GM) atrophy is recognized as a common feature of multiple sclerosis (MS), conflicting results have been obtained in patients with clinically isolated syndromes (CIS). Methodologic and clinical constraints may take account for literature discrepancies. METHODS:A total of 105 patients pr...

journal_title：Neurology

authors： Calabrese M,Rinaldi F,Mattisi I,Bernardi V,Favaretto A,Perini P,Gallo P

更新日期：2011-07-19 00:00:00

abstract：:The authors describe two patients with clinical manifestations of the osmotic demyelination syndrome (ODS) and unusual MRI findings of gadolinium-enhancing peripheral cortical abnormalities. They propose that these represent extrapontine manifestations of ODS because neither patient had a notable hypoxic-ischemic insu...

journal_title：Neurology

authors： Calakos N,Fischbein N,Baringer JR,Jay C

更新日期：2000-10-10 00:00:00

abstract：OBJECTIVE:To determine the prevalence and incidence of epilepsy among U.S. Medicare beneficiaries aged 65 years old and over, and to compare rates across demographic groups. METHODS:We performed a retrospective analysis of Medicare administrative claims for 2001-2005, defining prevalent cases as persons with ≥1 claim ...

journal_title：Neurology

authors： Faught E,Richman J,Martin R,Funkhouser E,Foushee R,Kratt P,Kim Y,Clements K,Cohen N,Adoboe D,Knowlton R,Pisu M

更新日期：2012-02-14 00:00:00

abstract：OBJECTIVE:Rebleeding of an aneurysm is a leading cause of morbidity and mortality after subarachnoid hemorrhage (SAH). Whereas numerous studies have demonstrated the risk factors associated with rebleeding, few data on complications of rebleeding, including its effect on the development of delayed cerebral ischemia (DC...

journal_title：Neurology

authors： Lord AS,Fernandez L,Schmidt JM,Mayer SA,Claassen J,Lee K,Connolly ES,Badjatia N

更新日期：2012-01-03 00:00:00

abstract：OBJECTIVE:To determine the diagnostic value of high-resolution ultrasound (HRUS) for detection of chronic inflammatory demyelinating polyneuropathy (CIDP), Lewis-Sumner syndrome (LSS), and multifocal motor neuropathy (MMN). METHODS:Between January 2013 and January 2015, we enrolled 75 consecutive treatment-naive patie...

journal_title：Neurology

authors： Goedee HS,van der Pol WL,van Asseldonk JH,Franssen H,Notermans NC,Vrancken AJ,van Es MA,Nikolakopoulos S,Visser LH,van den Berg LH

更新日期：2017-01-10 00:00:00

abstract：:We studied a patient in a minimally conscious state using PET and cognitive evoked potentials. Cerebral metabolism was below half of normal values. Auditory stimuli with emotional valence (infant cries and the patient's own name) induced a much more widespread activation than did meaningless noise; the activation patt...

journal_title：Neurology

authors： Laureys S,Perrin F,Faymonville ME,Schnakers C,Boly M,Bartsch V,Majerus S,Moonen G,Maquet P

更新日期：2004-09-14 00:00:00

abstract：:Titus Lucretius Carus was an ancient Roman philosopher of the Epicurean school whose epic poem On the Nature of Things described numerous aspects of the natural world. In fact, much contemporary scientific understanding is consistent with or inspired by his work. Among Lucretius's contributions to neurology were his d...

journal_title：Neurology

authors： Hyam JA,Paterson DJ,Aziz TZ,Green AL

更新日期：2011-09-06 00:00:00

abstract：BACKGROUND:Patients with arm intention tremor due to multiple sclerosis (MS) often manifest eye movement deficits, illustrating the role of infratentorial brain in both ocular and manual movement control. Our previous study showed that both the amplitude of intention tremor and eye fixational movements were greatly enh...

journal_title：Neurology

authors： Feys P,Helsen W,Nuttin B,Lavrysen A,Ketelaer P,Swinnen S,Liu X

更新日期：2008-01-08 00:00:00

abstract：:We evaluated the neuroprotective effect of MK-801, a noncompetitive, selective N-methyl-D-aspartate receptor antagonist, in a neonatal hypoxic-ischemic animal model. Seven-day-old rats underwent bilateral ligation of the carotid arteries followed by exposure to an 8% oxygen atmosphere for 1 hr. We sacrificed the anima...

journal_title：Neurology

authors： Hattori H,Morin AM,Schwartz PH,Fujikawa DG,Wasterlain CG

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:To determine the patterns of diffusivity associated with cognitive domain functions in older adults without dementia. METHODS:We studied older adults without dementia (n = 220) who underwent neuropsychometric testing and a diffusion tensor imaging (DTI) examination at 3 T in a cross-sectional study. Memory, ...

journal_title：Neurology

authors： Kantarci K,Senjem ML,Avula R,Zhang B,Samikoglu AR,Weigand SD,Przybelski SA,Edmonson HA,Vemuri P,Knopman DS,Boeve BF,Ivnik RJ,Smith GE,Petersen RC,Jack CR Jr

更新日期：2011-07-05 00:00:00

abstract：OBJECTIVE:The present retrospective cohort study compares the long-term functional outcome, improvement or deterioration, of patients considered in a vegetative state (VS) or a minimally conscious state (MCS) 1 year after coma onset, then yearly for up to 5 years. METHODS:We reviewed the clinical courses of 12 patient...

journal_title：Neurology

authors： Luauté J,Maucort-Boulch D,Tell L,Quelard F,Sarraf T,Iwaz J,Boisson D,Fischer C

更新日期：2010-07-20 00:00:00

abstract：:We tested the efficacy of coenzyme Q10 (ubidecarenone, CoQ10) therapy in patients with Kearns-Sayre syndrome and other mitochondrial myopathies with chronic progressive external ophthalmoplegia (CPEO). We treated seven patients for 1 year with daily oral administration of 120 mg of CoQ10. Throughout the treatment most...

journal_title：Neurology

authors： Bresolin N,Bet L,Binda A,Moggio M,Comi G,Nador F,Ferrante C,Carenzi A,Scarlato G

更新日期：1988-06-01 00:00:00

abstract：:A right-handed woman with independent left- and right-sided temporal lobe discharges was studied by continuous EEG and videotape monitoring for 3 weeks. Changes in affect were noted in the immediate and extended postictal periods and varied with the side of discharge. After a left-sided discharge, she became globally ...

journal_title：Neurology

authors： Hurwitz TA,Wada JA,Kosaka BD,Strauss EH

更新日期：1985-09-01 00:00:00

abstract：:Glucocorticoid therapy slows the progression of Duchenne muscular dystrophy. In muscle cultures, the addition of the glucocorticoid methylprednisolone increases myogenesis in most normal mixed and clonal cultures. Conversely, in some normal clonal and most dystrophic cultures, methylprednisolone inhibits fusion. Howev...

journal_title：Neurology

authors： Hardiman O,Sklar RM,Brown RH Jr

更新日期：1993-02-01 00:00:00

abstract：:To assess the role of current weekly alcohol consumption as a risk factor for cerebral infarction, we administered a pretested questionnaire to 205 middle-aged and elderly acute ischemic stroke patients and 410 outpatient controls matched by age, sex, race, and method of hospital payment. The frequency of hypertension...

journal_title：Neurology

authors： Gorelick PB,Rodin MB,Langenberg P,Hier DB,Costigan J

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:To determine whether quantitative whole-brain MR diffusion histograms in patients with MS differ from those of normal control subjects. BACKGROUND:MRI detects macroscopic cerebral lesions in MS, but the white matter lesion burden on MRI correlates imperfectly to clinical disability. Previous reports have fur...

journal_title：Neurology

authors： Nusbaum AO,Tang CY,Wei T,Buchsbaum MS,Atlas SW

更新日期：2000-04-11 00:00:00

abstract：:A comprehensive sequence analysis of 29 exons that code for the functional domains of LRRK2 in 160 nondominant Parkinson disease (PD) patients was performed. Novel variant screening in a further 470 sporadic PD patients and 630 controls revealed two novel variants (R1067Q and IVS33 + 6 T>A), which are likely to be pat...

journal_title：Neurology

authors： Skipper L,Shen H,Chua E,Bonnard C,Kolatkar P,Tan LC,Jamora RD,Puvan K,Puong KY,Zhao Y,Pavanni R,Wong MC,Yuen Y,Farrer M,Liu JJ,Tan EK

更新日期：2005-10-25 00:00:00

abstract：:A 11-year-old boy of short stature had recurrent right temporal pounding headaches of 7 months' duration, and progressive visual loss for 3 days. There was a left hemianopia, alexia without agraphia, and diffuse muscle weakness. Investigation established the presence of a mitochondrial myopathy with pyruvate and lacti...

journal_title：Neurology

authors： Skoglund RR

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that higher-challenge gait and balance tasks are more sensitive than traditional metrics to subtle patient-reported gait dysfunction and future fall risk in early multiple sclerosis (MS). METHODS:Persons with early MS (n = 185; ≤5 years diagnosed) reported gait function (MS Walking Sca...

journal_title：Neurology

authors： Brandstadter R,Ayeni O,Krieger SC,Harel NY,Escalon MX,Katz Sand I,Leavitt VM,Fabian MT,Buyukturkoglu K,Klineova S,Riley CS,Lublin FD,Miller AE,Sumowski JF

更新日期：2020-03-31 00:00:00

abstract：BACKGROUND:An association between primary hyperparathyroidism (PHP) and amyotrophic lateral sclerosis (ALS) has been noted; however, a causal relation between these disorders has not been confirmed. PATIENTS/METHODS:We report five patients (three men, two women) meeting El Escorial criteria for ALS who also had PHP. I...

journal_title：Neurology

authors： Jackson CE,Amato AA,Bryan WW,Wolfe GI,Sakhaee K,Barohn RJ

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To evaluate relationships among cognitive, behavioral, and psychiatric/psychosocial measures assessed in a multicenter cohort of patients with amyotrophic lateral sclerosis (ALS). METHODS:Recently diagnosed patients with definite or probable ALS diagnosis were administered 7 standardized psychiatric/psychoso...

journal_title：Neurology

authors： Rabkin J,Goetz R,Murphy JM,Factor-Litvak P,Mitsumoto H,ALS COSMOS Study Group.

更新日期：2016-09-27 00:00:00

abstract：OBJECTIVE:To report on the benefits of noninvasive vagus nerve stimulation (nVNS) on acute vestibular migraine (VM) treatment. METHODS:This was a retrospective chart review of patients with VM treated with nVNS in a single tertiary referral center between November 2017 and January 2019. Eighteen patients (16 women) we...

journal_title：Neurology

authors： Beh SC,Friedman DI

更新日期：2019-10-29 00:00:00