Abstract:
:A 11-year-old boy of short stature had recurrent right temporal pounding headaches of 7 months' duration, and progressive visual loss for 3 days. There was a left hemianopia, alexia without agraphia, and diffuse muscle weakness. Investigation established the presence of a mitochondrial myopathy with pyruvate and lactic acidemia and increased serum content of sarcoplasmic enzymes. On treatment with prednisone, the patient's strength and reading skill improved, symptoms resolved, and muscle enzymes returned to normal. Three attempts to reduce steroids resulted in accentuation of symptoms, seizures, weakness, regression of reading skills, and elevation of serum enzymes. The alexia was also reversible.
journal_name
Neurologyjournal_title
Neurologyauthors
Skoglund RRdoi
10.1212/wnl.29.5.717subject
Has Abstractpub_date
1979-05-01 00:00:00pages
717-20issue
5eissn
0028-3878issn
1526-632Xjournal_volume
29pub_type
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