Evidence for a genetic association between monoamine oxidase A and restless legs syndrome.

abstract：:Using a perceptual technique it is shown that patients with chronic external ophthalmoplegia have shortened vestibular responses. It is postulated that this is secondary to the retinal image slip experienced by these patients during head movements and a useful compensatory mechanism to suppress motion-induced sickness...

journal_title：Neurology

authors： Grunfeld EA,Shallo-Hoffmann JA,Cassidy L,Okada T,Faldon M,Acheson JF,Bronstein AM

更新日期：2003-06-24 00:00:00

abstract：OBJECTIVE:To evaluate the episodic migraine (EM)-obesity association and the influence of age, race, and sex on this relationship. METHODS:We examined the EM-obesity association and the influence of age, race, and sex in 3,862 adult participants of both black and white race interviewed in the National Comorbidity Surv...

journal_title：Neurology

authors： Peterlin BL,Rosso AL,Williams MA,Rosenberg JR,Haythornthwaite JA,Merikangas KR,Gottesman RF,Bond DS,He JP,Zonderman AB

更新日期：2013-10-08 00:00:00

abstract：BACKGROUND:The prevalence of symptoms suggesting distal symmetric polyneuropathy (DSP) was reported to be higher among deployed veterans (DV) to the Persian Gulf in 1990-1991 than to control non-deployed veterans (NDV). The authors therefore compared the prevalence of DSP by direct examination of DV and their spouses t...

journal_title：Neurology

authors： Davis LE,Eisen SA,Murphy FM,Alpern R,Parks BJ,Blanchard M,Reda DJ,King MK,Mithen FA,Kang HK

更新日期：2004-09-28 00:00:00

abstract：OBJECTIVE:To describe a large series of BIN1 patients, in which a novel founder mutation in the Roma population of southern Spain has been identified. METHODS:Patients diagnosed with centronuclear myopathy (CNM) at 5 major reference centers for neuromuscular disease in Spain (n = 53) were screened for BIN1 mutations. ...

journal_title：Neurology

authors： Cabrera-Serrano M,Mavillard F,Biancalana V,Rivas E,Morar B,Hernández-Laín A,Olive M,Muelas N,Khan E,Carvajal A,Quiroga P,Diaz-Manera J,Davis M,Ávila R,Domínguez C,Romero NB,Vílchez JJ,Comas D,Laing NG,Laporte J,Ka

更新日期：2018-07-24 00:00:00

abstract：:We investigated blood-brain barrier (BBB) function in relation to Alzheimer's disease (AD) and vascular dementia (VAD) in the very elderly. Sixty-five 85-year-old persons from a population-based sample were followed for 3 years; 29 were demented at age 85 (13 with AD, 14 with VAD, and 2 with other dementias), 7 develo...

journal_title：Neurology

authors： Skoog I,Wallin A,Fredman P,Hesse C,Aevarsson O,Karlsson I,Gottfries CG,Blennow K

更新日期：1998-04-01 00:00:00

abstract：:The effect of imipramine on the absorption of a single dose of levodopa was studied in male volunteers. By delaying gastric emptying and retarding delivery to intestinal absorptive sites, imipramine interfered with the absorption of levodopa. This action caused by the anticholinergic effect of imipramine. The retardat...

journal_title：Neurology

authors： Morgan JP,Rivera-Calimlim L,Messiha F,Sundaresan PR,Trabert N

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this cross-sectional study was to determine the prevalence and potential significance of stroke symptoms among end-stage renal disease (ESRD) patients without a prior diagnosis of stroke or TIA. METHODS:We enrolled 148 participants with ESRD from 5 clinics. Stroke symptoms and functional statu...

journal_title：Neurology

authors： Kurella Tamura M,Meyer JB,Saxena AB,Huh JW,Wadley VG,Schiller B

更新日期：2012-09-04 00:00:00

abstract：BACKGROUND:The Babinski sign is a well-known sign of upper motor neuron dysfunction that is widely considered an essential element of a complete neurologic examination. Little is known about reliability and validity of this sign. A less well-known sign of upper motor neuron dysfunction, decreased speed of foot tapping,...

journal_title：Neurology

authors： Miller TM,Johnston SC

更新日期：2005-10-25 00:00:00

abstract：:We report the cases of 5 patients from 2 sibships with the "adult" or chronic form of GM2 gangliosidosis and 2 patients from another sibship with the juvenile form. We demonstrated hexosaminidase A deficiency in all cases but in 1 sibship the enzymatic profile was identical to that in Tay-Sachs disease, whereas in the...

journal_title：Neurology

authors： Specola N,Vanier MT,Goutières F,Mikol J,Aicardi J

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:We developed the Recurrence and Recovery Questionnaire (RRQ) by converting the Pediatric Stroke Outcome Measure (PSOM) to a questionnaire for telephone interview and sought to validate the RRQ in a large cohort. METHOD:We analyzed parents' RRQ responses and same-day PSOM assessments for 232 children who had ...

journal_title：Neurology

authors： Lo WD,Ichord RN,Dowling MM,Rafay M,Templeton J,Halperin A,Smith SE,Licht DJ,Moharir M,Askalan R,Deveber G,International Pediatric Stroke Study (IPSS) Investigators.

更新日期：2012-08-28 00:00:00

abstract：:Normal human quadriceps muscle was transplanted into nude mice subcutaneously for periods of 1, 2, 3, 4, 6, and 8 weeks. At 1 week, there was myoblast and myotube formation with thin and thick filaments. After 2 weeks, there was myotube formation with partially cross-striated myofilaments, and formation of dyads or tr...

journal_title：Neurology

authors： Wakayama Y,Schotland DL,Bonilla E

更新日期：1980-07-01 00:00:00

abstract：OBJECTIVE:We pooled the results of studies on natural history of cavernous malformations (CM) to calculate point estimates and investigate main sources of heterogeneity. METHODS:We searched MEDLINE, EMBASE, and ISI Web of Science for relevant studies published before May 2015. We used fixed or random effects models an...

journal_title：Neurology

authors： Taslimi S,Modabbernia A,Amin-Hanjani S,Barker FG 2nd,Macdonald RL

更新日期：2016-05-24 00:00:00

abstract：:There was a report of spongiform encephalopathy transmitted to Syrian hamsters by intracerebral inoculation with the blood buffy coat of patients with Alzheimer's disease (AD) and their unaffected first-degree relatives. We attempted to verify that report, taking measures to reduce the risk of contaminating samples wi...

journal_title：Neurology

authors： Godec MS,Asher DM,Kozachuk WE,Masters CL,Rubi JU,Payne JA,Rubi-Villa DJ,Wagner EE,Rapoport SI,Schapiro MB

更新日期：1994-06-01 00:00:00

abstract：:We report cerebral vasculitis in 2 cocaine users who developed symptoms (transient blindness and persistent headache) while smoking "crack," followed by progressive widespread cerebral dysfunction with focal signs over the next few weeks. One patient had smoked crack exclusively, and the other also used cocaine intrav...

journal_title：Neurology

authors： Krendel DA,Ditter SM,Frankel MR,Ross WK

更新日期：1990-07-01 00:00:00

abstract：:We studied the effect of CSF drainage on cerebral blood flow (CBF) in normal pressure hydrocephalus (NPH) and non-NPH dementia using the 133Xenon inhalation technique. Dementia patients had lower CBF than matched elderly normals. Flow values for NPH and non-NPH patients did not differ before or after CSF drainage. CBF...

journal_title：Neurology

authors： Kushner M,Younkin D,Weinberger J,Hurtig H,Goldberg H,Reivich M

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVES:Patients surviving retinopathy-positive cerebral malaria (CM) are at high risk for the development of epilepsy, developmental disabilities, and behavioral abnormalities. We aimed to establish whether retinopathy-negative CM is also a risk factor for these outcomes. METHODS:Between 2005 and 2007, survivors o...

journal_title：Neurology

authors： Postels DG,Taylor TE,Molyneux M,Mannor K,Kaplan PW,Seydel KB,Chimalizeni YF,Kawaza K,Birbeck GL

更新日期：2012-09-18 00:00:00

abstract：OBJECTIVES:To investigate longitudinally the profile of cognitive impairment in nondemented patients with ALS. METHODS:Twenty nondemented patients with ALS and 18 controls were interviewed at two time points separated by a 6-month interval. The extensive battery was designed to accommodate the range of physical disabi...

journal_title：Neurology

authors： Abrahams S,Leigh PN,Goldstein LH

更新日期：2005-04-12 00:00:00

abstract：OBJECTIVE:To assess the clinical implications and the pathophysiologic determinants of interictal bitemporal hypometabolism (BTH) in temporal lobe epilepsy (TLE) not associated with bilateral MRI abnormalities or intracranial space-occupying lesions. METHODS:The authors compared the clinical, interictal, and ictal EEG...

journal_title：Neurology

authors： Koutroumanidis M,Hennessy MJ,Seed PT,Elwes RD,Jarosz J,Morris RG,Maisey MN,Binnie CD,Polkey CE

更新日期：2000-05-09 00:00:00

abstract：:Call-Fleming syndrome is a reversible segmental vasoconstriction of cerebral arteries manifested by a "thunderclap" headache and focal neurologic symptoms. Although of unknown etiology, it has been reported in association with vasoactive sympathomimetic drugs. The authors report Call-Fleming syndrome in two patients w...

journal_title：Neurology

authors： Noskin O,Jafarimojarrad E,Libman RB,Nelson JL

更新日期：2006-07-11 00:00:00

abstract：:In 64 patients with Parkinson's disease (PD), the basal level of prolactin (PRL) was normal. Bromocriptine (BCT) caused a significant suppression of PRL in all parkinsonian patients and controls. When given after BCT treatment, thyrotropin-releasing hormone (TRH) induced a significantly lower PRL rise in recent-onset ...

journal_title：Neurology

authors： Laihinen A,Rinne UK

更新日期：1986-03-01 00:00:00

abstract：:Ten patients are presented with severe dysarthria from a right hemisphere stroke, 4 with autopsies, emphasizing that this lesion alone is compatible with severely slurred speech. Most had oropharyngeal weakness; the accompanying hemiparesis was of variable severity. Superficial or deep infarctions were responsible, th...

journal_title：Neurology

authors： Ropper AH

更新日期：1987-06-01 00:00:00

abstract：:We present a clinical and morphological study concerning a kindred with slowly progressive X-linked muscular dystrophy (Becker type). Five males were affected; one died of heart failure at age 16. Severe and early cardiac disorder is unusual in this type of muscular dystrophy, and death at such an early age had not be...

journal_title：Neurology

authors： Kuhn E,Fiehn W,Schröder JM,Assmus H,Wagner A

更新日期：1979-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the risk of recurrent intracranial hemorrhage (ICH) in patients on vitamin K antagonists (VKAs) after a first episode of ICH. METHODS:The Cerebral Haemorrhage in patients Restarting Oral Anticoagulant Therapy (CHIRONE) Study collected data of patients eligible for the study from the database of 2...

journal_title：Neurology

authors： Poli D,Antonucci E,Dentali F,Erba N,Testa S,Tiraferri E,Palareti G,Italian Federation of Anticoagulation Clinics (FCSA).

更新日期：2014-03-25 00:00:00

abstract：:Charcot-Marie-Tooth disease type 1A (CMT1A) and hereditary neuropathy with liability to pressure palsies (HNPP) are inherited peripheral neuropathies. In most cases these disorders are caused by either the duplication (in CMT1A) or the deletion (in HNPP) of a 1.5-megabase DNA fragment on chromosome 17p11.2, which cont...

journal_title：Neurology

authors： Young P,Stögbauer F,Wiebusch H,Löfgren A,Timmerman V,Van Broeckhoven C,Ringelstein EB,Assmann G,Funke H

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To study the effect of pregnancy on the frequency of neuromyelitis optica spectrum disorder (NMOSD) relapse and evaluate rates of pregnancy-related complications in an international multicenter setting. METHODS:We administered a standardized survey to 217 women with NMOSD from 7 medical centers and reviewed ...

journal_title：Neurology

authors： Klawiter EC,Bove R,Elsone L,Alvarez E,Borisow N,Cortez M,Mateen F,Mealy MA,Sorum J,Mutch K,Tobyne SM,Ruprecht K,Buckle G,Levy M,Wingerchuk D,Paul F,Cross AH,Jacobs A,Chitnis T,Weinshenker B

更新日期：2017-11-28 00:00:00

abstract：:The authors report the neuropathologic findings in a case of Sneddon's syndrome. There were multiple small, predominantly cortical, infarcts, with focal hyperplasia and fibrotic occlusion of arterial vessels in the superficial white matter, cortex, and leptomeninges. A very occasional arterial thrombus was seen. These...

journal_title：Neurology

authors： Hilton DA,Footitt D

更新日期：2003-04-08 00:00:00

abstract：:We examined the performance of patients with probable Alzheimer's disease (AD) who participated in the placebo arm of a 12-week clinical trial. Assessments occurred at baseline and at 4, 6, 10, and 12 weeks after starting study medication. Patients received the Alzheimer's Disease Assessment Scale--Cognitive on all fi...

journal_title：Neurology

authors： Knopman D,Gracon S

更新日期：1994-02-01 00:00:00

abstract：:Spontaneous circadian fluctuations of motor symptoms in Parkinson's disease (PD) often occur, with dysfunction typically less severe in the early morning than in the afternoon. In 23 PD patients with or without a history of circadian motor fluctuations, we studied contrast sensitivity (CS), a non-motor function, consi...

journal_title：Neurology

authors： Struck LK,Rodnitzky RL,Dobson JK

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:To assess the determinants of amyotrophic lateral sclerosis (ALS) phenotypes in a population-based cohort. METHODS:The study population included 2,839 patients with ALS diagnosed in Piemonte, Italy (1995-2015). Patients were classified according to motor (classic, bulbar, flail arm, flail leg, predominantly ...

journal_title：Neurology

authors： Chiò A,Moglia C,Canosa A,Manera U,D'Ovidio F,Vasta R,Grassano M,Brunetti M,Barberis M,Corrado L,D'Alfonso S,Iazzolino B,Peotta L,Sarnelli MF,Solara V,Zucchetti JP,De Marchi F,Mazzini L,Mora G,Calvo A

更新日期：2020-02-25 00:00:00

abstract：:Creutzfeldt-Jakob disease was studied among Libyan-born Israelis, in whom the disease appears with unusual frequency. Interviews with relatives of deceased victims revealed statistically significant clustering within families. The results suggest either a common source of exposure or a genetic influence on susceptibil...

journal_title：Neurology

authors： Neugut RH,Neugut AI,Kahana E,Stein Z,Alter M

更新日期：1979-02-01 00:00:00