Abstract:
:Hippocampal sulcal cavities are usually considered incidental findings on brain MRI. In a group of 92 elderly volunteers, the authors graded the number and size of hippocampal sulcal cavities with brain MRI to obtain a cavity score. Cavity scores increased with age, and were higher in subjects carrying the APOE epsilon4 or epsilon2 alleles than in subjects with the epsilon3/3 genotype. Age-related morphologic changes in the hippocampus may be mediated by the APOE genotype.
journal_name
Neurologyjournal_title
Neurologyauthors
Barboriak DP,Doraiswamy PM,Krishnan KR,Vidyarthi S,Sylvester J,Charles HCdoi
10.1212/wnl.54.11.2150subject
Has Abstractpub_date
2000-06-13 00:00:00pages
2150-3issue
11eissn
0028-3878issn
1526-632Xjournal_volume
54pub_type
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