Abstract:
:We report 9 patients with an isolated infarct of the anterior part of the rostral cerebellum, ie, the territory of the lateral branch of the superior cerebellar artery. Clinicoanatomic correlations are based on CT, MRI, or both in 8 patients and on pathologic data in the ninth. The main clinical features were ipsilateral dysmetria and axial lateropulsion, dysarthria, and unsteadiness. In 1 patient, the clinical presentation mimicked a lacunar stroke (dysarthria and clumsy hand syndrome). There were no edematous cerebellar infarcts with signs of brainstem compression, and all patients spontaneously improved without significant sequellae. Angiography in 2 patients and pathologic examination of arteries in 1 patient disclosed no occlusion in the vertebrobasilar system. Six patients had a cardiac source of emboli. In conclusion, infarcts of the anterior part of the rostral cerebellum can be regarded as a benign condition in which there is, frequently, a cardiac source of emboli.
journal_name
Neurologyjournal_title
Neurologyauthors
Amarenco P,Roullet E,Goujon C,Chéron F,Hauw JJ,Bousser MGdoi
10.1212/wnl.41.2_part_1.253subject
Has Abstractpub_date
1991-02-01 00:00:00pages
253-8issue
2 ( Pt 1)eissn
0028-3878issn
1526-632Xjournal_volume
41pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::In the coterminous United States, MS mortality rates demonstrate a north-south gradient, which is confirmed by more sophisticated--and more expensive--prevalence studies. Mortality rates from idiopathic Parkinson's disease show a similar north-south gradient, and they correlate significantly with the MS mortality and ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.37.3.467
更新日期:1987-03-01 00:00:00
abstract:OBJECTIVE:To evaluate levels of neurofilament light (NFL) and glial fibrillary acidic protein (GFAP) in CSF from patients with multiple sclerosis (MS) in relation to clinical progress of the disease. METHODS:CSF levels of NFL and GFAP were determined by sensitive ELISAs in 99 patients with different subtypes of MS, cl...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000142988.49341.d1
更新日期:2004-11-09 00:00:00
abstract::Eighty-five healthy elderly subjects were prospectively evaluated for 3 years to determine motor differences between those who remain cognitively intact and those who developed cognitive impairment during prospective follow-up. The 18 subjects who developed cognitive impairment had slower finger tapping and took longe...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.50.5.1496
更新日期:1998-05-01 00:00:00
abstract::Two women with myasthenia gravis became apneic immediately after IV injection of iodinated contrast material for CT. Aggravation of myasthenia continued for days after this initial reaction. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.35.8.1219
更新日期:1985-08-01 00:00:00
abstract:OBJECTIVE:In addition to the main multiple sclerosis (MS) major histocompatibility complex (MHC) risk allele (HLA DRB1*1501), investigations of the MHC have implicated several class I MHC loci (HLA A, HLA B, and HLA C) as potential independent MS susceptibility loci. Here, we evaluate the role of 3 putative protective ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181ed9c9c
更新日期:2010-08-17 00:00:00
abstract:OBJECTIVE:There is a high risk of readmission within 30 days of index acute ischemic stroke (AIS), but effect of readmission to a different hospital is not known. We performed a retrospective cohort study to assess our hypothesis that 30-day readmission outcomes after AIS are worse for those readmitted to another hospi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000008446
更新日期:2019-11-12 00:00:00
abstract::Serum from 35 cases of naturally occurring acquired canine myasthenia gravis (MG) were assayed for patterns of autoantibody specificities against canine acetylcholine receptor (AChR) using monoclonal antibodies (mAbs) and antiserum against defined regions of the AChR as competitive inhibitors of autoantibody binding. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.9.1417
更新日期:1988-09-01 00:00:00
abstract::The authors describe a case of neurologic involvement in mild hyperphenylalaninemia (HPA), not due to tetrahydrobiopterin (BH(4)) deficiency, with low levels of monoamine neurotransmitter metabolites in CSF. The combined BH(4)-Phe loading test suggested a BH(4) response, confirmed by clinical improvement after BH(4) t...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.5.908
更新日期:2001-09-11 00:00:00
abstract:BACKGROUND:Evidence linking APOE to myelin repair, neuronal plasticity, and cerebral inflammatory processes suggests that it may be relevant in multiple sclerosis (MS). The purpose of this study was to determine whether the epsilon4 allele of APOE is associated with cognitive deficits in patients with MS. METHOD:Using...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181e074a7
更新日期:2010-05-18 00:00:00
abstract::Patients, clinicians, and hospitals have undergone monumental changes during the coronavirus disease 2019 (COVID-19) pandemic. This crisis has forced us to consider the obligations that we neurologists have to our individual patients as well as the greater community. By returning to our fundamental understanding of th...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000009744
更新日期:2020-07-28 00:00:00
abstract:OBJECTIVE:To determine the contribution of sequence variations in PHOX2B to sudden unexpected death in epilepsy (SUDEP). METHODS:Patients who died of SUDEP were identified in 2 major Australian cohorts, the Epilepsy Genetics research program in Melbourne and postmortem cases at the Department of Forensic Medicine in S...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000000781
更新日期:2014-09-09 00:00:00
abstract:OBJECTIVE:To explore the inflammatory processes in the pathogenesis of psychiatric symptoms and the prognostic value of psychiatric comorbidities in multiple sclerosis (MS). METHODS:Four hundred five patients with relapsing-remitting (RR) MS underwent psychiatric evaluation by means of Beck Depression Inventory II (BD...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000004411
更新日期:2017-09-26 00:00:00
abstract:BACKGROUND:Although phenylketonuria is a treatable disease, patients with late or nonoptimal phenylalanine-restricted diet may experience brain damage. The authors used tridimensional MRI and a voxelwise analysis method to investigate possible volume changes in the brain parenchyma of patients with phenylketonuria. ME...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000204415.39853.4a
更新日期:2006-04-11 00:00:00
abstract:OBJECTIVE:Eleven genetic loci have reached genome-wide significance in a recent meta-analysis of genome-wide association studies in Parkinson disease (PD) based on populations of Caucasian descent. The extent to which these genetic effects are consistent across different populations is unknown. METHODS:Investigators f...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e318264e353
更新日期:2012-08-14 00:00:00
abstract::The clinical and electroencephalographic (EEG) effects of sodium valproate were studied in four patients by means of serial 24-hour EEG recordings and simultaneous hourly determinations of serum drug concentrations. The patients all had frequent clinical seizures and generalized spike-wave discharges. Valproate appear...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.29.11.1450
更新日期:1979-11-01 00:00:00
abstract::We studied the effects of botulinum toxin A in 12 patients with spasticity and in eight patients with rigidity. The study design was a double-blind, placebo-controlled crossover trial with botulinum toxin A versus saline. Using the Ashworth Scale for spasticity and the Unified Parkinson's Disease Rating Scale for rigi...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.45.4.712
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:Asians who carry the HLA-B*1502 allele have an elevated risk of developing Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) when treated with the antiepileptic drugs (AEDs) carbamazepine (CBZ) and phenytoin (PHT). With a focus on Singapore, this analysis identifies circumstances in which ge...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31826aac73
更新日期:2012-09-18 00:00:00
abstract:OBJECTIVES:To further improve the distinction between primary angiitis of the CNS (PACNS) and reversible cerebral vasoconstriction syndrome (RCVS). METHODS:We compared 2 large French cohorts of patients with PACNS (n = 110, retrospectively and prospectively enrolled) and RCVS (n = 173, prospectively enrolled). RESULT...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006367
更新日期:2018-10-16 00:00:00
abstract::A patient with thymoma-associated neuromyotonia and voltage-gated potassium channel (Kv1.2 and Kv1.6) antibodies by immunoprecipitation and rat brain immunolabeling was treated successfully with immunoadsorption and cyclophosphamide. Curiously, glutamic acid decarboxylase antibodies, absent at onset, appeared later. S...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000156945.39471.2C
更新日期:2005-04-12 00:00:00
abstract:OBJECTIVE:To investigate the association of PD with preceding head trauma using a case-control study design. METHODS:The medical records-linkage system of the Rochester Epidemiology Project was used to identify 196 subjects who developed PD in Olmsted County, MN, from 1976 through 1995. Each incident case was matched ...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/01.wnl.0000068008.78394.2c
更新日期:2003-05-27 00:00:00
abstract:OBJECTIVE:To determine possible effects of prolonged marijuana use on the cerebrovascular system during a month of monitored abstinence and to assess how the intensity of current use might have influenced cerebrovascular perfusion in these marijuana users. METHOD:The authors recorded blood flow velocity in the anterio...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000150882.69371.DD
更新日期:2005-02-08 00:00:00
abstract:OBJECTIVE:To study the usefulness of corticospinally mediated excitatory responses and transcallosal inhibition (TI) elicited by transcranial magnetic stimulation (TMS) as a surrogate marker of disability in patients with different courses of MS. METHODS:Focal TMS of the motor cortex was performed in 118 patients with...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.59.8.1218
更新日期:2002-10-22 00:00:00
abstract:OBJECTIVE:In children with sickle cell disease (SCD), silent cerebral infarcts are the most frequent cause of neurologic injury. We determined the sensitivity and specificity of selective neurocognitive measures when separating children with silent cerebral infarcts and SCD from sibling controls. Additionally, we teste...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.6.1678
更新日期:1998-06-01 00:00:00
abstract::A 3-year old, previously well child developed paroxysms of left thigh pain. Evaluation was unremarkable except for interictal and postictal EEG epileptiform activity in the right parietal and posterior temporal regions. The painful spells were controlled with anticonvulsant medication. Episodes of paroxysmal, unexplai...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.2.329
更新日期:1988-02-01 00:00:00
abstract::Rosenthal fibers are present in several neurologic disorders. Their occurrence in widespread subependymal, subpial, and perivascular locations is thought to be diagnostic of Alexander's disease, but they have also been reported in rare adult cases. Some of these patients were neurologically intact with severe systemic...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.9.1733
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:To determine if migraine with aura is associated with neuroinflammation, which has been suggested by preclinical models of cortical spreading depression (CSD) as well as imaging of human pain conditions. METHODS:Thirteen migraineurs with aura and 16 healthy controls received integrated PET/MRI brain scans wi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000007371
更新日期:2019-04-23 00:00:00
abstract::Over the past 5 years, and especially within the last year, there has been a rapid expansion of vagus nerve stimulation (VNS)-related preclinical research, as well as clinical studies in indications other than epilepsy. The research advances in understanding VNS are occurring in the midst of a blossoming of other form...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.59.6_suppl_4.s56
更新日期:2002-09-24 00:00:00
abstract:OBJECTIVE:To determine whether droxidopa, an oral norepinephrine precursor, improves symptomatic neurogenic orthostatic hypotension (nOH). METHODS:Patients with symptomatic nOH due to Parkinson disease, multiple system atrophy, pure autonomic failure, or nondiabetic autonomic neuropathy underwent open-label droxidopa ...
journal_title:Neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1212/WNL.0000000000000615
更新日期:2014-07-22 00:00:00
abstract::Eighteen patients with congenital nystagmus were studied with the techniques of electronystagmography and computer analysis. We found several complex wave forms of congenital nystagmus in the primary position of gaze above those of jerk and pendular nystagmus as defined clinically. An etiologic classification of motor...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.26.4.326
更新日期:1976-04-01 00:00:00
abstract::In 47 patients with Parkinson's disease, we studied the visual evoked potential (VEP) using the pattern-reversal checkerboard (CBVEP) and the grating (GVEP) stimuli before and after 3 months of L-dopa therapy. The P100 latency in both CBVEP and GVEP was prolonged before L-dopa therapy, usually commensurate with the de...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.8.1119
更新日期:1986-08-01 00:00:00