Botulinum toxin A for spasticity, muscle spasms, and rigidity.

abstract：OBJECTIVE:To determine the rate of relapse occurrence during pregnancy and postpartum. METHODS:In a cross-sectional study using the national multiple sclerosis (MS) registry, pregnant women with relapsing MS were identified. Data on demographics, clinical characteristics, and disease-modifying therapies (DMTs), includ...

journal_title：Neurology

authors： Alroughani R,Alowayesh MS,Ahmed SF,Behbehani R,Al-Hashel J

更新日期：2018-03-06 00:00:00

abstract：BACKGROUND:Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome is a rare multisystem disorder associated with plasma cell dyscrasia. There is increasing evidence that high-dose chemotherapy with autologous peripheral blood stem cell transplantation (Auto-PBSCT) is an efficacious t...

journal_title：Neurology

authors： Kuwabara S,Misawa S,Kanai K,Suzuki Y,Kikkawa Y,Sawai S,Hattori T,Nishimura M,Nakaseko C

更新日期：2008-11-18 00:00:00

abstract：:Two patients with neglect for extrapersonal space following right-hemisphere stroke both demonstrated retained ability to attend to the left side of internally generated visual images. The attentional system for extrapersonal space may not be identical to the attentional system for intrapersonal space. ...

journal_title：Neurology

authors： Anderson B

更新日期：1993-01-01 00:00:00

abstract：:The authors sequenced the entire mitochondrial DNA coding region in a group of 19 patients with non-arteritic anterior ischemic optic neuropathy (NAION) and in 100 controls. Synonymous and nonsynonymous nucleotide changes were more common in NAION patients (p < 0.001). Twelve of these (11 novel) were potentially patho...

journal_title：Neurology

authors： Bosley TM,Abu-Amero KK,Ozand PT

更新日期：2004-10-12 00:00:00

abstract：OBJECTIVE:To determine if migraine with aura is associated with neuroinflammation, which has been suggested by preclinical models of cortical spreading depression (CSD) as well as imaging of human pain conditions. METHODS:Thirteen migraineurs with aura and 16 healthy controls received integrated PET/MRI brain scans wi...

journal_title：Neurology

authors： Albrecht DS,Mainero C,Ichijo E,Ward N,Granziera C,Zürcher NR,Akeju O,Bonnier G,Price J,Hooker JM,Napadow V,Loggia ML,Hadjikhani N

更新日期：2019-04-23 00:00:00

abstract：OBJECTIVE:To provide a comprehensive understanding of APOE ε4 effects across the lifespan on the 3 main neuroimaging biomarkers. METHODS:Two hundred seven community-dwelling, cognitively normal APOE ε4 carriers and noncarriers aged 20-87 years were involved in this study. They underwent structural MRI, fluorodeoxygluc...

journal_title：Neurology

authors： Gonneaud J,Arenaza-Urquijo EM,Fouquet M,Perrotin A,Fradin S,de La Sayette V,Eustache F,Chételat G

更新日期：2016-10-18 00:00:00

abstract：:Three sisters with adult fucosidosis showed prominent psychomotor retardation, gargoyle features, and angiokeratoma corporis diffusum, meeting the criteria for type II fucosidosis. By histochemical and ultrastructural studies, biopsy of rectal mucosa revealed many abnormal macrophages that were filled with fucose-rich...

journal_title：Neurology

authors： Ikeda S,Kondo K,Oguchi K,Yanagisawa N,Horigome R,Murata F

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVE:Motor signs are functionally disabling features of Huntington disease. Characteristic motor signs define disease manifestation. Their severity and onset are assessed by the Total Motor Score of the Unified Huntington's Disease Rating Scale, a categorical scale limited by interrater variability and insensitivi...

journal_title：Neurology

authors： Bechtel N,Scahill RI,Rosas HD,Acharya T,van den Bogaard SJ,Jauffret C,Say MJ,Sturrock A,Johnson H,Onorato CE,Salat DH,Durr A,Leavitt BR,Roos RA,Landwehrmeyer GB,Langbehn DR,Stout JC,Tabrizi SJ,Reilmann R

更新日期：2010-12-14 00:00:00

abstract：OBJECTIVE:Development of an easy to administer, low-cost test of vestibular function. METHODS:Members of the NIH Toolbox Sensory Domain Vestibular, Vision, and Motor subdomain teams collaborated to identify 2 tests: 1) Dynamic Visual Acuity (DVA), and 2) the Balance Accelerometry Measure (BAM). Extensive work was comp...

journal_title：Neurology

authors： Rine RM,Schubert MC,Whitney SL,Roberts D,Redfern MS,Musolino MC,Roche JL,Steed DP,Corbin B,Lin CC,Marchetti GF,Beaumont J,Carey JP,Shepard NP,Jacobson GP,Wrisley DM,Hoffman HJ,Furman G,Slotkin J

更新日期：2013-03-12 00:00:00

abstract：:Lubag (X-linked dystonia-parkinsonism) has been considered a sex-linked recessive trait and has been mapped to the pericentromeric region of the X chromosome. We studied a 54-year-old man with lubag and two of his female first cousins. Genetic typing was carried out using X chromosome markers. Fluorodopa PET was perfo...

journal_title：Neurology

authors： Waters CH,Takahashi H,Wilhelmsen KC,Shubin R,Snow BJ,Nygaard TG,Moskowitz CB,Fahn S,Calne DB

更新日期：1993-08-01 00:00:00

abstract：:We evaluated the accuracy and interobserver variability of selected ictal and postictal behavioral changes. Three observers, blinded to clinical history, EEG, and side of surgical resection, analyzed videotapes of 166 seizures in 38 patients, looking for lateralizing signs. Twenty-seven patients with temporal lobe res...

journal_title：Neurology

authors： Chee MW,Kotagal P,Van Ness PC,Gragg L,Murphy D,Lüders HO

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To report the CNS syndromes of patients ≥60 years of age with antibodies against neuronal surface antigens but no evidence of brain MRI and CSF inflammatory changes. METHODS:This was a retrospective clinical analysis of patients with antibodies against neuronal surface antigens who fulfilled 3 criteria: age ...

journal_title：Neurology

authors： Escudero D,Guasp M,Ariño H,Gaig C,Martínez-Hernández E,Dalmau J,Graus F

更新日期：2017-10-03 00:00:00

abstract：OBJECTIVES:To further improve the distinction between primary angiitis of the CNS (PACNS) and reversible cerebral vasoconstriction syndrome (RCVS). METHODS:We compared 2 large French cohorts of patients with PACNS (n = 110, retrospectively and prospectively enrolled) and RCVS (n = 173, prospectively enrolled). RESULT...

journal_title：Neurology

authors： de Boysson H,Parienti JJ,Mawet J,Arquizan C,Boulouis G,Burcin C,Naggara O,Zuber M,Touzé E,Aouba A,Bousser MG,Pagnoux C,Ducros A

更新日期：2018-10-16 00:00:00

abstract：OBJECTIVE:To determine the relative efficacy of amantadine, pemoline, and placebo in treatment of multiple sclerosis (MS)-related fatigue. BACKGROUND:Fatigue is a complication of MS. Both pemoline and amantadine have been used to treat MS fatigue, but their relative efficacy is not known. METHODS:Amantadine, pemoline...

journal_title：Neurology

authors： Krupp LB,Coyle PK,Doscher C,Miller A,Cross AH,Jandorf L,Halper J,Johnson B,Morgante L,Grimson R

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To empirically validate the expanded concept of mild cognitive impairment (MCI), which differentiates between four clinical subtypes-amnestic MCI-single domain, amnestic MCI-multiple domains, nonamnestic MCI-single domain, and nonamnestic MCI-multiple domains-and to examine the prevalence, course, and outcome...

journal_title：Neurology

authors： Busse A,Hensel A,Gühne U,Angermeyer MC,Riedel-Heller SG

更新日期：2006-12-26 00:00:00

abstract：:We report 9 patients with an isolated infarct of the anterior part of the rostral cerebellum, ie, the territory of the lateral branch of the superior cerebellar artery. Clinicoanatomic correlations are based on CT, MRI, or both in 8 patients and on pathologic data in the ninth. The main clinical features were ipsilate...

journal_title：Neurology

authors： Amarenco P,Roullet E,Goujon C,Chéron F,Hauw JJ,Bousser MG

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant disorder that manifests as recurrent, episodic, painful brachial neuropathies. A gene for HNA maps to chromosome 17q25.3 where mutations in SEPT9, encoding the septin-9 protein, have been identified. OBJECTIVE:To determine the frequency and type...

journal_title：Neurology

authors： Hannibal MC,Ruzzo EK,Miller LR,Betz B,Buchan JG,Knutzen DM,Barnett K,Landsverk ML,Brice A,LeGuern E,Bedford HM,Worrall BB,Lovitt S,Appel SH,Andermann E,Bird TD,Chance PF

更新日期：2009-05-19 00:00:00

abstract：:Compressive neuropathy due to tight application of handcuffs occurred in 5 patients. The superficial radial nerve was affected in 8 hands and the median nerve in two. Neurologic deficits persisted as long as 3 years after handcuffing. Nerve conduction studies helped to exclude malingering and other diagnoses. All pati...

journal_title：Neurology

authors： Stone DA,Laureno R

更新日期：1991-01-01 00:00:00

abstract：:Multiple chemical and coagulation determinations were undertaken on the subdural hematoma fluid from the reformed effusions of two patients. It was found that plasma or blood repeatedly reentered the subdural cavity. Coagulation studies compared the in vitro effects of subdural fluid with those of cerebrospinal fluid,...

journal_title：Neurology

authors： Labadie EL,Glover D

更新日期：1975-07-01 00:00:00

abstract：:The defect occurring when a patient fails to report a visual stimulus presented in a visual half-field may be attributed to hemianopia (deafferentation) caused by a geniculocalcarine lesion. However, failure to report a stimulus presented in a visual field may also be caused by hemispatial visual inattention. We repor...

journal_title：Neurology

authors： Kooistra CA,Heilman KM

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:To examine the association between cognitive function and dementia with vitamin D concentration in adults. METHODS:Five databases were searched for English-language studies up to August 2010, and included all study designs with a comparative group. Cognitive function or impairment was defined by tests of glo...

journal_title：Neurology

authors： Balion C,Griffith LE,Strifler L,Henderson M,Patterson C,Heckman G,Llewellyn DJ,Raina P

更新日期：2012-09-25 00:00:00

abstract：:Neurologic complications of brain tissue-derived rabies vaccine may be chronic or progressive. Lymphocytes and serum from three patients with this form of encephalitis were studied. Two patients had positive lymphoproliferation to purified myelin, two had antibody to white matter, and one had antibody to myelin basic ...

journal_title：Neurology

authors： Hemachudha T,Griffin DE,Johnson RT,Giffels JJ

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To define the clinical and radiologic features of brainstem gliomas (BSGs) in children with neurofibromatosis type 1 (NF1). METHODS:We performed a retrospective cross-sectional study of 133 children with NF1 and concurrent BSGs cared for at 4 NF1 referral centers. BSG was determined using radiographic criter...

journal_title：Neurology

authors： Mahdi J,Shah AC,Sato A,Morris SM,McKinstry RC,Listernick R,Packer RJ,Fisher MJ,Gutmann DH

更新日期：2017-04-18 00:00:00

abstract：OBJECTIVE:To investigate the etiology of aseptic meningitis and encephalitis in an adult population using modern microbiologic methods. METHODS:Consecutive patients (ages > or =16) with aseptic meningitis or encephalitis treated in Turku University Hospital, Finland, during 1999 to 2003 were included in the study. Mic...

journal_title：Neurology

authors： Kupila L,Vuorinen T,Vainionpää R,Hukkanen V,Marttila RJ,Kotilainen P

更新日期：2006-01-10 00:00:00

abstract：:We followed 419 patients with a first, unprovoked, primarily or secondarily generalized tonic-clonic seizure, randomized to immediate antiepileptic treatment or to treatment only in the event of seizure recurrence. The probability of achieving a 2-year remission was 72 vs 57% at 3 months, 84 to 79% at 3 years, and 85 ...

journal_title：Neurology

authors： Leone MA,Solari A,Beghi E,FIRST Group.

更新日期：2006-12-26 00:00:00

abstract：:The association between multiple sclerosis (MS) and alleles of the HLA class II genes indicates that at least one MS susceptibility gene is linked to the HLA class II region. However, the actual locus responsible has not been precisely identified. The recent cloning of new genes involved in antigen processing that map...

journal_title：Neurology

authors： Liblau R,van Endert PM,Sandberg-Wollheim M,Patel SD,Lopez MT,Land S,Fugger L,McDevitt HO

更新日期：1993-06-01 00:00:00

abstract：:Idiopathic trigeminal sensory neuropathy is a benign disorder. We report two patients with transient MRI abnormalities, suggesting transient inflammation of the trigeminal nerve caused temporary facial sensory symptoms. ...

journal_title：Neurology

authors： Rorick MB,Chandar K,Colombi BJ

更新日期：1996-05-01 00:00:00

abstract：:We evaluated the effects of isoniazid on tremor in 13 patients with MS. Patients were evaluated before treatment, after 1 month of therapy (1,000 mg daily), and 1 month after the last dose. Ten patients improved on at least one of three methods of evaluation. Transient side effects were common, possibly because there ...

journal_title：Neurology

authors： Duquette P,Pleines J,du Souich P

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To compare the accuracy of Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and CT perfusion to detect established infarction in acute anterior circulation stroke. METHODS:We performed an observational study in 59 acute anterior circulation ischemic stroke patients who underwent brain noncont...

journal_title：Neurology

authors： Demeestere J,Garcia-Esperon C,Garcia-Bermejo P,Ombelet F,McElduff P,Bivard A,Parsons M,Levi C

更新日期：2017-06-13 00:00:00

abstract：:We detected crossed cerebellar as well as uncrossed basal ganglia and thalamic diaschisis in Alzheimer's disease by positron emission tomography (PET) using 18F-fluorodeoxyglucose. We studied a series of 26 consecutive, clinically diagnosed Alzheimer cases, including 6 proven by later autopsy, and compared them with 9...

journal_title：Neurology

authors： Akiyama H,Harrop R,McGeer PL,Peppard R,McGeer EG

更新日期：1989-04-01 00:00:00