Abstract:
:Multiple chemical and coagulation determinations were undertaken on the subdural hematoma fluid from the reformed effusions of two patients. It was found that plasma or blood repeatedly reentered the subdural cavity. Coagulation studies compared the in vitro effects of subdural fluid with those of cerebrospinal fluid, serum, and a buffer control. Despite some chemical differences, the subdural fluids from both patients behaved similarly by (1) accelerating the intrinsic clotting system, (2) producing defective clot formation, and (3) accelerating the fibrinolytic system. It is presumed that these continuous hemostatic-fibrinolytic alterations, acting in the subdural sac, may have important implications in the growth and reformation of subdural hematomas, and a hypothesis of the mechanisms involved is presented.
journal_name
Neurologyjournal_title
Neurologyauthors
Labadie EL,Glover Ddoi
10.1212/wnl.25.7.669subject
Has Abstractpub_date
1975-07-01 00:00:00pages
669-75issue
7eissn
0028-3878issn
1526-632Xjournal_volume
25pub_type
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