Abstract:
:Rosenthal fibers are present in several neurologic disorders. Their occurrence in widespread subependymal, subpial, and perivascular locations is thought to be diagnostic of Alexander's disease, but they have also been reported in rare adult cases. Some of these patients were neurologically intact with severe systemic illnesses. In symptomatic cases, the neurologic disorder has simulated multiple sclerosis. We report an elderly woman with progressive parkinsonism, dementia, and hallucinations whose brain showed severe Rosenthal fiber proliferation.
journal_name
Neurologyjournal_title
Neurologyauthors
Friedman JH,Ambler Mdoi
10.1212/wnl.42.9.1733subject
Has Abstractpub_date
1992-09-01 00:00:00pages
1733-5issue
9eissn
0028-3878issn
1526-632Xjournal_volume
42pub_type
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