Abstract:
:There has been disagreement about the precise characteristics of "subcortical aphasia." We evaluated 14 patients with aphasia after subcortical lesions and controlled for duration, general anatomic site of lesions (capsulostriatal only), and etiology. The clinical profiles of the patients were quite similar, varying in severity in rough proportion to lesion size and varying in quality in proportion to anterior paraventricular extent. Large lesions were associated with impaired "executive" and "generative" language functions. Similar aphasia profiles in patients with deep frontal and paraventricular white matter lesions suggest that damage to a frontal-caudate functional system underlies a "core" aphasia profile in these patients.
journal_name
Neurologyjournal_title
Neurologyauthors
Mega MS,Alexander MPdoi
10.1212/wnl.44.10.1824subject
Has Abstractpub_date
1994-10-01 00:00:00pages
1824-9issue
10eissn
0028-3878issn
1526-632Xjournal_volume
44pub_type
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