Subcortical aphasia: the core profile of capsulostriatal infarction.

Abstract:

:There has been disagreement about the precise characteristics of "subcortical aphasia." We evaluated 14 patients with aphasia after subcortical lesions and controlled for duration, general anatomic site of lesions (capsulostriatal only), and etiology. The clinical profiles of the patients were quite similar, varying in severity in rough proportion to lesion size and varying in quality in proportion to anterior paraventricular extent. Large lesions were associated with impaired "executive" and "generative" language functions. Similar aphasia profiles in patients with deep frontal and paraventricular white matter lesions suggest that damage to a frontal-caudate functional system underlies a "core" aphasia profile in these patients.

journal_name

Neurology

journal_title

Neurology

authors

Mega MS,Alexander MP

doi

10.1212/wnl.44.10.1824

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

1824-9

issue

10

eissn

0028-3878

issn

1526-632X

journal_volume

44

pub_type

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