Abstract:
:A 42-year-old man had progressive distal weakness and muscle atrophy, stocking-type sensory loss, upper motor-neuron and visual pathway lesions, and dysautonomia. Electrodiagnostic tests revealed a generalized sensorimotor peripheral neuropathy that largely involved axons. Low recumbent and upright norepinephrine levels implied a peripheral autonomic defect. Sural nerve biopsy showed mild abnormalities of medium and small size fibers. The patient's mother and two brothers were also affected. Other causes of peripheral motor, sensory, and autonomic failure were eliminated. This kinship does not fit any generally accepted classification of hereditary neuropathies.
journal_name
Neurologyjournal_title
Neurologyauthors
Rechthand E,Reife R,Kaplan JGdoi
10.1212/wnl.33.11.1495subject
Has Abstractpub_date
1983-11-01 00:00:00pages
1495-7issue
11eissn
0028-3878issn
1526-632Xjournal_volume
33pub_type
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