Differential decrease of copper content and of copper binding to superoxide dismutase in liver, heart and brain of copper-deficient rats.

abstract：:Platelet adhesion to VLDL, LDL, HDL, and to a mixture of purified apolipoproteins was examined. Platelets adhered to all the classes of lipoproteins tested. VLDL and the apolipoprotein mixture promoted the greatest degree of adhesion. Platelet adhesion was inhibited by addition of EDTA, RGD-containing peptides and ant...

journal_title：Biochemical and biophysical research communications

authors： Kowalska MA,Tuszynski GP,Capuzzi DM

更新日期：1990-10-15 00:00:00

abstract：:The insulin receptor gene is induced 8 to 10-fold during adipocyte differentiation. Plasmids containing the promoter, exon 1 and a portion of the first intron from either the mouse or human gene are able to modulate the expression of an insulin receptor/CAT gene 3 to 7-fold during differentiation. We have shown that s...

journal_title：Biochemical and biophysical research communications

authors： McKeon C,Accili D,Chen H,Pham T,Walker GE

更新日期：1997-11-26 00:00:00

abstract：:Disrupted-In-Schizophrenia 1 (DISC1) was identified as a novel gene disrupted by a (1;11)(q42.1;q14.3) translocation segregating with schizophrenia, bipolar disorder and other major mental illnesses in a Scottish family. We previously identified 446-533 amino acids of DISC1 as the kendrin-binding region by means of a ...

journal_title：Biochemical and biophysical research communications

authors： Shimizu S,Matsuzaki S,Hattori T,Kumamoto N,Miyoshi K,Katayama T,Tohyama M

更新日期：2008-12-26 00:00:00

abstract：:Recent studies have demonstrated that adult cells such as pancreatic exocrine cells can be converted to pancreatic β-cells in a process called cell reprogramming. Enteroendocrine cells and β-cells share similar pathways of differentiation during embryonic development. Notably, enteroendocrine K cells express many of t...

journal_title：Biochemical and biophysical research communications

authors： Lee E,Ryu GR,Moon SD,Ko SH,Ahn YB,Song KH

更新日期：2014-01-17 00:00:00

abstract：:Tyrosine protein kinase activity was measured in membranes from DMBA-induced mammary tumors, with Angiotensin II as substrate. The apparent Km for the peptide was 3.3 mM. This enzymatic activity is inhibited by Ca+2; Mn+2 can replace Mg+2 with an increase in the Km for ATP from 47 /microM to 172 microM. The enzymatic ...

journal_title：Biochemical and biophysical research communications

authors： Levy J,Teuerstein I,Marbach M,Radian S,Sharoni Y

更新日期：1984-09-28 00:00:00

abstract：:Circadian rhythmic disorders induced by high-fat diet are associated with metabolic diseases. Resveratrol could improve metabolic disorder, but few reports focused on its effects on circadian rhythm disorders in a variety of studies. The aim of the present study was to analyze the potential effects of resveratrol on h...

journal_title：Biochemical and biophysical research communications

authors： Sun L,Wang Y,Song Y,Cheng XR,Xia S,Rahman MR,Shi Y,Le G

更新日期：2015-02-27 00:00:00

abstract：:The synthesis of toxin protein from Ustilago maydis virus (UmV) strain P4 was studied in vitro and in vivo. The protein synthesized in vitro and in vivo has a molecular weight of approximately 30 kd whereas the native toxin has a molecular weight of about 12 kd. In the presence of protease inhibitors and glycosylation...

journal_title：Biochemical and biophysical research communications

authors： Podila GK,Bozarth RF,Flurkey WH

更新日期：1987-12-16 00:00:00

abstract：:RNA polymerase III promoters of human ribonuclease P RNA component H1, human U6, and mouse U6 small nuclear RNA genes are commonly used in short hairpin RNA (shRNA) expression vectors due their precise initiation and termination sites. During transient transfection of shRNA vectors, we observed that H1 or U6 promoters...

journal_title：Biochemical and biophysical research communications

authors： Rumi M,Ishihara S,Aziz M,Kazumori H,Ishimura N,Yuki T,Kadota C,Kadowaki Y,Kinoshita Y

更新日期：2006-01-13 00:00:00

abstract：:Under nitrosative stressed condition intracellular GSNO accumulation is common to all cell types. Conserved NADH-dependent GSNO reductase was reported previously as an important cellular protective measure against this. In spite of the constitutive nature of the enzyme, we observed in vivo inactivation of two importan...

journal_title：Biochemical and biophysical research communications

authors： Sahoo R,Sengupta R,Ghosh S

更新日期：2003-03-21 00:00:00

abstract：:Th2 type immune responses are essential for protective immunity against parasites and play crucial roles in allergic disorders. Helminth parasites secrete a variety of proteases for their infectious cycles including for host entry, tissue migration, and suppression of host immune effector cell function. Furthermore, a...

journal_title：Biochemical and biophysical research communications

authors： Nishikado H,Fujimura T,Taka H,Mineki R,Ogawa H,Okumura K,Takai T

更新日期：2015-05-01 00:00:00

abstract：:In order to investigate tooth development, several cell lines of the dental epithelium and ectomesenchyme have been established. However, no attempt has been reported to regenerate teeth with cell lines. Here, we have established several clonal cell lines of the dental epithelium from a p53-deficient fetal mouse. They...

journal_title：Biochemical and biophysical research communications

authors： Komine A,Suenaga M,Nakao K,Tsuji T,Tomooka Y

更新日期：2007-04-13 00:00:00

abstract：:The whole-cell patch-clamp technique has been applied to elucidate the effects of H2O2 and the SH-group reagent 2,2'-dithio-bis(5-nitropyridine) (DTBNP) on Ca2+ currents of mouse pancreatic B-cells. We also tested the effect of DTBNP on the whole-cell K+ ATP current. DTBNP (20 and 100 mumol/l) blocked both the current...

journal_title：Biochemical and biophysical research communications

authors： Krippeit-Drews P,Britsch S,Lang F,Drews G

更新日期：1994-04-29 00:00:00

abstract：:The Tat protein from HIV-1 fused with heterologous proteins traverses biological membranes in a transcellular process called: protein transduction. This has already been successfully exploited in various biological models, but never in the nematode worm Caenorhabditis elegans. TAT-eGFP or GST-eGFP proteins were fed to...

journal_title：Biochemical and biophysical research communications

authors： Delom F,Fessart D,Caruso ME,Chevet E

更新日期：2007-01-19 00:00:00

abstract：:The effect of the interleukin-1 receptor antagonist (IL-1ra) on development of hyperglycemia and insulitis in mice treated with multiple low doses of streptozotocin (STZ) was evaluated. C57BL/Ks mice were subjected to the following treatments: 1) Injections i.p. of phosphate-buffered saline (PBS) alone; 2) STZ (5 x 40...

journal_title：Biochemical and biophysical research communications

authors： Sandberg JO,Andersson A,Eizirik DL,Sandler S

更新日期：1994-07-15 00:00:00

abstract：:Calyculin A (CL-A), a toxin isolated from the marine sponge Discodermia calyx, is a strong inhibitor of protein phosphatase 1 (PP1) and 2A (PP2A). Although CL-A is known to induce rapid neurite retraction in developing neurons, the cytoskeletal dynamics of this retraction have remained unclear. Here, we investigated t...

journal_title：Biochemical and biophysical research communications

authors： Inutsuka A,Goda M,Fujiyoshi Y

更新日期：2009-12-25 00:00:00

abstract：:This study examined the actions of L-arginine, a putative precursor of endothelium-derived nitric oxide, and arginine analogs on endothelium-dependent relaxation of isolated rings of bovine pulmonary artery. L-Arginine did not consistently relax arterial rings unless rings were first rendered refractory to endothelium...

journal_title：Biochemical and biophysical research communications

authors： Gold ME,Wood KS,Buga GM,Byrns RE,Ignarro LJ

更新日期：1989-06-15 00:00:00

abstract：:Vinculin and meta-vinculin are related proteins that localize to adherens junctions. To facilitate studies on the biology of these proteins cDNA clones were isolated from a chick embryonic library made in lambda gt 11. Three clones, accounting for 1/2 of the vinculin message, were identified by immunological analyses ...

journal_title：Biochemical and biophysical research communications

authors： Coutu MD,Simon DJ,Brown AE,Craig SW

更新日期：1987-09-15 00:00:00

abstract：:The Na(+)/K(+) ATPase generates the Na(+) and K(+) concentration gradients across the plasma membrane and is thus essential for cellular electrolyte homeostasis, cell membrane potential and cell volume maintenance. A powerful regulator of Na(+)/K(+) ATPase is the serum- and glucocorticoid-inducible kinase 1 (SGK1). Th...

journal_title：Biochemical and biophysical research communications

authors： Hosseinzadeh Z,Schmid E,Shumilina E,Laufer S,Borst O,Gawaz M,Lang F

更新日期：2014-09-26 00:00:00

abstract：:In this study, we report the effect of endothelial progenitor cells (EPCs) on the biological behavior of osteoclast precursors in vitro by establishing an indirect co-culture system of mice EPCs and RAW 264.7 monocyte cells. Results show that the survival, migration, and differentiation of osteoclast precursors were g...

journal_title：Biochemical and biophysical research communications

authors： Pang H,Wu XH,Fu SL,Luo F,Zhang ZH,Hou TY,Li ZQ,Chang ZQ,Yu B,Xu JZ

更新日期：2013-01-11 00:00:00

abstract：:Imipenem is often used to treat intensive care unit patients infected by Enterobacter aerogenes, but it is leading to an increasing number of antibiotic resistant strains. Clinical isolates and imipenem resistant variants presented a high level of resistance to beta-lactam antibiotic group and to chemically unrelated ...

journal_title：Biochemical and biophysical research communications

authors： Bornet C,Chollet R,Malléa M,Chevalier J,Davin-Regli A,Pagès JM,Bollet C

更新日期：2003-02-21 00:00:00

abstract：:The vast majority of ovarian cancers originate in the ovarian surface epithelium. Unfortunately, there is a lack of appropriate animal models for ovarian cancer research. Spontaneously transformed mouse ovarian surface epithelial cells may provide a faithful animal model for human ovarian cancer. One such cell line (I...

journal_title：Biochemical and biophysical research communications

authors： Pengetnze Y,Steed M,Roby KF,Terranova PF,Taylor CC

更新日期：2003-09-19 00:00:00

abstract：:Patients in end-stage renal disease (ESRD) have a high incidence of bacterial and viral infections. Fifteen non-dialysed (ND), 15 haemodialysed (HD), 15 patients with peritoneal dialysis (PD), and 15 healthy controls were included. T cell proliferation was measured by [3H]thymidine uptake. Apoptosis and cell phenotype...

journal_title：Biochemical and biophysical research communications

authors： Moser B,Roth G,Brunner M,Lilaj T,Deicher R,Wolner E,Kovarik J,Boltz-Nitulescu G,Vychytil A,Ankersmit HJ

更新日期：2003-08-29 00:00:00

abstract：:CDX2 is an intestine-specific tumor suppressor gene encoding homeodomain-containing transcription factor, which is involved in a variety of developmental, proliferating, and differentiating processes. Moreover, the expression of CDX2 is reduced in a subset of primary colorectal cancers. In contrast, cyclooxygenase-2 (...

journal_title：Biochemical and biophysical research communications

authors： Kim SP,Park JW,Lee SH,Lim JH,Jang BC,Lee SH,Jang IH,Freund JN,Suh SI,Mun KC,Song DK,Ha EM,Lee WJ,Kwon TK

更新日期：2004-02-27 00:00:00

abstract：:MUC1 is abundantly expressed at the surface of epithelial cells in many tissues and their carcinomas. In humans, genetic polymorphism and differential splicing produce isoforms that may contribute to MUC1 participation in protection of the cell surface, modulation of cell-cell interactions, signaling, and metastasis. ...

journal_title：Biochemical and biophysical research communications

authors： Julian J,Carson DD

更新日期：2002-05-17 00:00:00

abstract：:Small heat-shock proteins (sHSPs) represent an abundant and ubiquitous family of molecular chaperones. The current model proposes that sHSPs function to prevent irreversible aggregation of non-native proteins by forming soluble complex. The chaperone activity of sHSPs is usually determined by the capacity to suppress ...

journal_title：Biochemical and biophysical research communications

authors： Jiao W,Li P,Zhang J,Zhang H,Chang Z

更新日期：2005-09-16 00:00:00

abstract：:Human dendritic cells (DC) are key regulators of innate and adaptive immunity that can be divided in at least three major subpopulations: plasmacytoid DC (pDC), myeloid type 1 DC (mDC1) and myeloid type 2 DC (mDC2) exhibiting different functions. However, research, diagnostic and cell therapeutic studies on human DC s...

journal_title：Biochemical and biophysical research communications

authors： Schütz F,Hackstein H

更新日期：2014-01-10 00:00:00

abstract：:The pathway employed for pentachlorophenol (PCP) degradation by an aerobic, chlorophenol-utilizing Flavobacterium sp. was initiated by conversion of PCP to tetrachloro-p-hydroquinone (TCH). 18O labelling experiments demonstrated that the first dechlorination, where a hydroxyl replaced the chlorine at PCP ring position...

journal_title：Biochemical and biophysical research communications

authors： Steiert JG,Crawford RL

更新日期：1986-12-15 00:00:00

abstract：:Fifteen luciferase plasmid constructs driven by various promoters including cytomegalovirus (CMV), Rous sarcoma virus (RSV), human serum albumin (SA), alpha-1 antitrypsin (AAT), cytochrome P450 CYP1A2, CYP2C9, CYP2C18, CYP2D6, CYP3A4, mouse CYP2b10, human amyloid precursor protein (APP), chicken beta actin (ACT), nucl...

journal_title：Biochemical and biophysical research communications

authors： Al-Dosari M,Zhang G,Knapp JE,Liu D

更新日期：2006-01-13 00:00:00

abstract：:The direct interaction of protein kinase C with the nucleus was examined utilizing endogenous protein phosphorylation and [3H]PDBu binding to detect the enzyme. Rat brain nuclei were relatively rich in phorbol ester receptors whereas liver nuclei contained less than 10% of their brain counterpart. Purified protein kin...

journal_title：Biochemical and biophysical research communications

authors： Misra UK,Sahyoun N

更新日期：1987-06-15 00:00:00

abstract：:We previously reported that the suppression of SIRT2, an NAD + -dependent protein deacetylases, induces p53 accumulation via degradation of p300 and the subsequent MDM2 degradation, eventually leading to apoptosis in HeLa cells. The present study identified a novel pathway of p53 accumulation by SIRT2 suppression in H...

journal_title：Biochemical and biophysical research communications

authors： Li Y,Kokura K,Inoue T

更新日期：2019-01-01 00:00:00