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Synthesis and processing of killer toxin from Ustilago maydis virus P4.

Abstract：

:The synthesis of toxin protein from Ustilago maydis virus (UmV) strain P4 was studied in vitro and in vivo. The protein synthesized in vitro and in vivo has a molecular weight of approximately 30 kd whereas the native toxin has a molecular weight of about 12 kd. In the presence of protease inhibitors and glycosylation inhibitors, toxin protein synthesized in vivo showed higher molecular weight products that could be immunoprecipitated with toxin antibodies. These results suggest that the UmV P4 toxin protein is synthesized as a preprotein, which upon processing results in the 12 kd secreted form toxin.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Podila GK,Bozarth RF,Flurkey WH

doi

10.1016/0006-291x(87)90379-2

subject

Has Abstract

pub_date

1987-12-16 00:00:00

pages

391-7

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(87)90379-2

journal_volume

149

pub_type

杂志文章

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