Tooth regeneration from newly established cell lines from a molar tooth germ epithelium.

abstract：:The composition of intestinal glycosphingolipids during normal and hormone-perturbed development was investigated. The concentrations of glycosphingolipids of mouse small intestine were affected by the injection of thyroxine or cortisone during suckling and weaning periods. GDla was reduced by the hormonal treatment a...

journal_title：Biochemical and biophysical research communications

authors： Sato E,Fujie M,Uezato T,Fujita M,Nishimura K

更新日期：1984-03-30 00:00:00

abstract：:Diphtheria toxin (DT) binds to a specific heparin-binding epidermal growth factor-like growth factor (HB-EGF) precursor that is expressed in DT-sensitive cells. DT binds to the cell-surface HB-EGF precursor with an apparent dissociation constant (KD) of approximately 1 x 10(-8) - 10(-9) M at 4 degreesC, a temperature ...

journal_title：Biochemical and biophysical research communications

authors： Brooke JS,Cha JH,Eidels L

更新日期：1998-07-20 00:00:00

abstract：:X-linked Emery-Dreifuss muscular dystrophy is usually caused by absence of the nuclear membrane protein, emerin, due to nonsense mutations or deletions, but a few missense mutations also exist. A pathogenic g993t mutation causes a Q133H change in the nuclear targeting region of emerin, but it may also reduce emerin le...

journal_title：Biochemical and biophysical research communications

authors： Holt I,Clements L,Manilal S,Morris GE

更新日期：2001-10-12 00:00:00

abstract：:Cellular prion protein, PrP(C), is essential for the development of prion diseases where it is considered to be a substrate for the formation of the disease-associated conformer, PrP(Sc). In sheep, PrP(C) is abundant in neuronal tissue and is also found at lower concentrations in a range of non-neuronal tissues, inclu...

journal_title：Biochemical and biophysical research communications

authors： Maddison BC,Whitelam GC,Gough KC

更新日期：2007-02-02 00:00:00

abstract：:The Rex-family repressors sense redox levels by alternative binding to NADH or NAD(+). RSP is the homologue of Rex in Thermoanaerobacter ethanolicus JW200(T) and regulates ethanol fermentation in this obligate anaerobe. The dimeric repressor binds to DNA by an open conformation. The crystal structure of RSP/α-NAD(+) c...

journal_title：Biochemical and biophysical research communications

authors： Zheng Y,Ko TP,Yang Y,Shao W,Guo RT

更新日期：2015-01-16 00:00:00

abstract：:Translationally controlled tumor protein (TCTP) is often designated as a stress-related protein because of its highly regulated expression in stress conditions. Following a thermal shock, TCTP expression is highly upregulated in a variety of cells. However, at present it is not known whether this upregulation has any ...

journal_title：Biochemical and biophysical research communications

authors： Gnanasekar M,Dakshinamoorthy G,Ramaswamy K

更新日期：2009-08-21 00:00:00

abstract：:Lysophosphatidylcholine (lyso-PC), a biologically active phospholipid, appears to modulate various endothelial cell functions through tyrosine kinase-dependent signaling pathways. In cultured bovine aortic endothelial cells (BAEC), we have found that a 130 kDa protein (p130) was rapidly tyrosine phosphorylated within ...

journal_title：Biochemical and biophysical research communications

authors： Ochi H,Kume N,Nishi E,Moriwaki H,Masuda M,Fujiwara K,Kita T

更新日期：1998-02-24 00:00:00

abstract：:Autophagy has been implicated in several neurodegenerative diseases and recently its role in acute brain injury has received increased interest. In our study, we investigated the profiles of autophagy-linked proteins (MAP-LC3 (Atg8), beclin-1 (Atg6) and the beclin-1-binding protein, bcl-2, following controlled cortica...

journal_title：Biochemical and biophysical research communications

authors： Sadasivan S,Dunn WA Jr,Hayes RL,Wang KK

更新日期：2008-09-05 00:00:00

abstract：:Atherosclerosis-related vascular complications in beta-thalassemia/hemoglobin E (beta-thal/Hb E) patients may result from iron induced oxidation of lipoproteins. To identify the specific site of oxidative damage, changes in lipid fluidity at different regions in LDL and HDL particle were investigated using two fluores...

journal_title：Biochemical and biophysical research communications

authors： Morales NP,Charlermchoung C,Luechapudiporn R,Yamanont P,Fucharoen S,Chantharaksri U

更新日期：2006-11-24 00:00:00

abstract：:LFA-1 (αLβ2) and Mac-1 (αMβ2) integrins regulate leukocyte trafficking in health and disease by binding primarily to IgSF ligand ICAM-1 and ICAM-2 on endothelial cells. Here we have shown that the anti-coagulant molecule thrombomodulin (TM), found on the surface of endothelial cells, functions as a potentially new lig...

journal_title：Biochemical and biophysical research communications

authors： Kawamoto E,Okamoto T,Takagi Y,Honda G,Suzuki K,Imai H,Shimaoka M

更新日期：2016-05-13 00:00:00

abstract：:Baculovirus p35 belongs to the early class of genes of AcMNPV and requires viral factors like Immediate Early protein-1 for its transcription. To investigate the role of host factors in regulating p35 gene expression, the putative transcription factor binding sites were examined in silico and the role of these factors...

journal_title：Biochemical and biophysical research communications

authors： Mohareer K,Sahdev S,Hasnain SE

更新日期：2011-11-04 00:00:00

abstract：:Two-stage rat hepatocarcinogenesis model was used to induce early carcinogenesis in which thioacetamide (TAA) promotes diethylnitrosamine (DEN) initiated carcinogenesis. Dimethyl fumarate (DMF) used to treat multiple sclerosis, activates the nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant responsive ele...

journal_title：Biochemical and biophysical research communications

authors： Dwivedi DK,Jena GB

更新日期：2020-02-05 00:00:00

abstract：:Genome-wide association studies identified ADAMTS7 as a risk locus for coronary artery disease. In carotid arteries of rats, neointima formation after balloon-mediated injury goes along with enhanced Adamts7 expression. Vice versa, Adamts7-deficient mice display reduced neointima formation following vascular injury. A...

journal_title：Biochemical and biophysical research communications

authors： Müller M,Kessler T,Schunkert H,Erdmann J,Tennstedt S

更新日期：2016-03-11 00:00:00

abstract：:An important role for the Rel/NF-kappaB family of transcription factors in the differentiation process of dendritic cells (DC) and macrophages (MAC) was recently suggested by a number of mouse knockout studies but only little information is available for defined populations of human cells. To investigate the role of i...

journal_title：Biochemical and biophysical research communications

authors： Ammon C,Mondal K,Andreesen R,Krause SW

更新日期：2000-02-05 00:00:00

abstract：:The pancreatic islets of Langerhans produce several peptide hormones, predominantly the metabolically active hormones insulin and glucagon, which are critical for maintaining normal fuel homeostasis. Some evidence exists that pancreatic endocrine cells turn over at a slow rate and can regenerate in certain conditions....

journal_title：Biochemical and biophysical research communications

authors： Hunziker E,Stein M

更新日期：2000-04-29 00:00:00

abstract：:A novel [125I]-labelled photoaffinity ligand designed to detect cannabinoid binding sites has been used in mouse brain preparations and in cultured S49 mouse lymphoma cells. The ligand, 2-iodo-5'-azido-delta 8-THC, shows a high affinity for sites in both brain (Kd = 5.60 pM) and whole cell (Kd = 9.38 pM) systems. Phot...

journal_title：Biochemical and biophysical research communications

authors： Burstein SH,Audette CA,Charalambous A,Doyle SA,Guo Y,Hunter SA,Makriyannis A

更新日期：1991-04-15 00:00:00

abstract：:Opioid agonists either potentiate or suppress basal cAMP production in SK-N-SH cells. The inhibitory effect is mediated by PTX-sensitive GTP-binding proteins, while the stimulatory effect involves Ca++ entry and calmodulin activation. Both pathways can be activated simultaneously by opioid agonists. Low (nM) concentra...

journal_title：Biochemical and biophysical research communications

authors： Sarne Y,Rubovitch V,Fields A,Gafni M

更新日期：1998-05-08 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a prevalent malignancy with increasing incidence and extremely poor prognosis worldwide. The multi-kinase inhibitor sorafenib is widely used as a first-line systematic treatment agent of advanced hepatocellular carcinoma. However, the benefit of sorafenib in clinical treatment is ofte...

journal_title：Biochemical and biophysical research communications

authors： Long Q,Zou X,Song Y,Duan Z,Liu L

更新日期：2019-06-04 00:00:00

abstract：:The C-terminal alpha-amide formation of the peptides is one of the most important events of prohormone processing. We have recently isolated an alpha-amidating enzyme, AE-I, from Xenopus laevis skin, which is the only enzyme ever purified to homogeneity. In this study, we report cloning and sequence of cDNA encoding A...

journal_title：Biochemical and biophysical research communications

authors： Mizuno K,Ohsuye K,Wada Y,Fuchimura K,Tanaka S,Matsuo H

更新日期：1987-10-29 00:00:00

abstract：:Most vertebrates possess at least two gonadotropin-releasing hormone (GnRH) neuron types. To understand the physiological significance of the multiple GnRH systems in the brain, we examined three GnRH neuron type-specific transcriptomes using single-cell microarray analyses in the medaka (Oryzias latipes). A microarra...

journal_title：Biochemical and biophysical research communications

authors： Moriya S,Ogawa S,Parhar IS

更新日期：2013-06-14 00:00:00

abstract：:It is still unclear whether an active state of transcription once established in chromatin persists in neurons. Here, we focused on BDNF exon I-IX mRNA expression because of its marked induction upon the treatment of rat cortical neurons with trichostatin A, suggesting strong repression of the expression through histo...

journal_title：Biochemical and biophysical research communications

authors： Hara D,Miyashita T,Fukuchi M,Suzuki H,Azuma Y,Tabuchi A,Tsuda M

更新日期：2009-12-18 00:00:00

abstract：:Advanced glomerulosclerosis, a common hallmark of chronic renal diseases (CRD) is believed to be irreversible, and it is thought that glomerular hyperfiltration and hypertrophy may participate in its pathogenesis. We demonstrate here that glomerulosclerosis is "reversible" in an animal model. We used nephrotic ICGN (n...

journal_title：Biochemical and biophysical research communications

authors： Mizuno-Horikawa Y,Mizuno S,Tamura S,Kurosawa T

更新日期：2001-06-15 00:00:00

abstract：:Autoimmune sera showing prominent immunofluorescence in nucleolus were selected and analysed by immunoblotting techniques. Immunoblots using a nucleolar extract as antigen source revealed sera recognizing a 38 kDa nucleolar protein. Low concentration of Actinomycin D, which inhibits the ribosomal RNA synthesis, caused...

journal_title：Biochemical and biophysical research communications

authors： Kindås-Mügge I

更新日期：1989-09-15 00:00:00

abstract：:Serine proteinase inhibitors are widely distributed in nature and inhibit the activity of enzymes like trypsin and chymotrypsin. These proteins interfere with the physiological processes such as germination, maturation and form the first line of defense against the attack of seed predator. The most thoroughly examined...

journal_title：Biochemical and biophysical research communications

authors： Sattar R,Ali SA,Kamal M,Khan AA,Abbasi A

更新日期：2004-02-13 00:00:00

abstract：:Effective treatment of neuropathic pain is challenging as its underlying mechanism remains largely unknown. Recently, the participation of brain-derived neurotrophic factor (BDNF) in neuropathic pain has been attracting increased attention. BDNF binds to a member of the tyrosine kinase receptor family, the TrkB recept...

journal_title：Biochemical and biophysical research communications

authors： Ikeda K,Hazama K,Itano Y,Ouchida M,Nakatsuka H

更新日期：2020-10-20 00:00:00

abstract：:Protein transduction domains (PTDs) are short amino acid sequences that promote their own translocation across the cell plasma membrane and have been studied for possible use in drug delivery and gene therapy. However, no direct method to quantify transduction is available. Here, using a new luciferase-tagged human PT...

journal_title：Biochemical and biophysical research communications

authors： Lee MS,Kwon EH,Choi HS,Kwon SH,Lee CH,Shim IS,Lee SK,Her S

更新日期：2010-04-02 00:00:00

abstract：:The HSP30 gene of the budding yeast Saccharomyces cerevisiae encodes a seven-transmembrane heat shock protein expressed in response to various types of stress including heat shock. Although Hsp30p contains a potential N-glycosylation consensus sequence (Asn(2)-Asp(3)-Thr(4)), whether it is actually N-glycosylated has ...

journal_title：Biochemical and biophysical research communications

authors： Kamo K,Takabatake A,Inoue Y,Izawa S

更新日期：2012-03-30 00:00:00

abstract：:ABCG2 (also called MXR (3), BCRP (4), or ABCP (5) is a recently-identified ABC half-transporter, which causes multidrug resistance in cancer. Here we report that the expression of the ABCG2 protein in Sf9 insect cells resulted in a high-capacity, vanadate-sensitive ATPase activity in isolated membrane preparations. AB...

journal_title：Biochemical and biophysical research communications

authors： Ozvegy C,Litman T,Szakács G,Nagy Z,Bates S,Váradi A,Sarkadi B

更新日期：2001-07-06 00:00:00

abstract：:After parallel hybridization to complementary template RNA, alpha-anomeric oligonucleotides are not primers for Moloney murine leukemia virus reverse transcriptase. As can be expected they are competitors of classical primer oligonucleotides (beta-anomeric). They therefore inhibit the RNA dependent DNA polymerase acti...

journal_title：Biochemical and biophysical research communications

authors： Lavignon M,Bertrand JR,Rayner B,Imbach JL,Malvy C,Paoletti C

更新日期：1989-06-30 00:00:00

abstract：:To investigate the role of secondary structure in the substrate specificity of human 72 kDa type IV collagenase, we synthesised linear and cyclic collagen sequence analogs. As Ca2+ plays a crucial role in the enzyme activity, the CD and FTIR spectra of the peptides were also measured in the presence of Ca2+. Most of t...

journal_title：Biochemical and biophysical research communications

authors： Likó Z,Botyánszki J,Bódi J,Vass E,Majer Z,Hollósi M,Süli-Vargha H

更新日期：1996-10-14 00:00:00