Selective and prolonged MRI enhancement by Mn-TPPS in an experimental rat brain tumour with peripheral benzodiazepine receptors.

abstract：:The objective of this study was to determine, whether 0.5-2/min oscillations in intracranial pressure ('B-waves') are a physiological phenomenon. In a group of 5 patients 0.5-2/min oscillations of ventricular pressure simultaneous with oscillations in the middle cerebral artery (MCA) flow velocity, as assessed by tran...

journal_title：Neurological research

authors： Mautner-Huppert D,Haberl RL,Dirnagl U,Villringer A,Schmiedek P,Einhäupl K

更新日期：1989-12-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative motor neuron disease in adults, whose relentless course leads to death within 2-5 years, generally due to respiratory failure. Apart from the age and site of onset, no other factors have consistently demonstrated to be related to the ALS outc...

journal_title：Neurological research

authors： Dedic SI,Stevic Z,Dedic V,Stojanovic VR,Milicev M,Lavrnic D

更新日期：2012-07-01 00:00:00

abstract：:A new and reproducible saccular aneurysm model has been developed at the bifurcation of the common carotid artery in rats. The details of the experimental methods and results are described. It is strongly suggested that the internal elastic lamina is a critical layer in saccular aneurysm formation, because an experime...

journal_title：Neurological research

authors： van Alphen HA,Gao YZ,Kamphorst W

更新日期：1990-12-01 00:00:00

abstract：:Decreased metabolic rate may precede cognitive impairment in Alzheimer's disease (AD) and is thus an early occurring hallmark. Several observations in post-mortem brain indicate that activated neurons are better able to withstand aging and AD, a phenomenon paraphrased by us as 'use it or lose it'. Moreover, a number o...

journal_title：Neurological research

authors： Swaab DF

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:There is no definitive data regarding the usefulness of Brain microbleeds (BMBs) as an imaging marker with homeostatic markers to predict intracerebral hemorrhage (ICH) and ischemic stroke risk to personalize decisions on anticoagulation in AF. In this study, we prospectively evaluated clinical, radiological...

journal_title：Neurological research

authors： Altintas O,Niftaliyev E,Asil T

更新日期：2018-12-01 00:00:00

abstract：:This article covers the basis of tethered cord syndrome as a stretch-induced spinal cord disorder, including pathophysiology, signs and symptoms, imaging diagnosis, indication for surgical treatment, and surgical procedures. Anomalies that cause mechanical spinal cord tethering are listed, and the surgical untethering...

journal_title：Neurological research

authors： Yamada S,Won DJ,Siddiqi J,Yamada SM

更新日期：2004-10-01 00:00:00

abstract：:The ocular microtremor (OMT) is mediated by the oculomotor area of the brainstem and is altered in several pathologic states, including traumatic brain injury, general anesthesia, brain death, coma, Parkinsonism and multiple sclerosis. The EYETECT tremor monitor is a non-invasive means of measuring the frequency and a...

journal_title：Neurological research

authors： Robertson J,Timmons S

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for pre-operative planning and functional neurona...

journal_title：Neurological research

authors： Berntsen EM,Samuelsen P,Lagopoulos J,Rasmussen IA Jr,Håberg AK,Haraldseth O

更新日期：2008-11-01 00:00:00

abstract：:Objectives: Neurovascular compression syndromes (NVCS) could be cured with an intravascular device that releases compression of the root entry zone of cranial nerves by changing the course of offending vessels. The purpose of this study was to report our results of in vitro and in vivo experiments with a novel intra-a...

journal_title：Neurological research

authors： Chun Y,Chen Y,Elsisy M,Sukinik J,Shridhar P,Park JK,Kim YB,Hong CK,Chung J

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Daughter aneurysms have been strongly associated with saccular aneurysm rupture. We constructed a mathematical model to help explain this association as a possible hemodynamic mechanism for intracranial saccular aneurysm rupture. METHODS:Our model is based on the assumption that when an aneurysm reaches a s...

journal_title：Neurological research

authors： Meng H,Feng Y,Woodward SH,Bendok BR,Hanel RA,Guterman LR,Hopkins LN

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:In this study, we aimed to investigate the effect of bone mesenchymal stem cells (BMSCs) conditioned medium on BMP4-induced activation of the Smad signaling pathway during the process of neural stem cells differentiation. METHODS:We designed four experimental groups: (A) control group, (B) BMP-4 treatment g...

journal_title：Neurological research

authors： Fang H,Song P,Shen C,Liu X,Li H

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To assess the effect of sensory nerve stimulation in older people with peripheral neuropathy associated with diabetes (DPN). MATERIALS AND METHODS:A randomized, placebo controlled, double blind trial was used to assess the effect of 12 weeks of low frequency sensory nerve stimulation (LF-SNS) in the lower li...

journal_title：Neurological research

authors： Khalil Z,Ogrin R,Darzins PJ

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The role of inflammation in cognitive alterations in a post-operative setting is still not fully understood. Surgical interventions can cause systemic inflammations which eventually can induce neuroinflammation. However, the main causes of functional changes after surgery are still elusive. In this study, we ...

journal_title：Neurological research

authors： Schnitzler S,Kopitz J,Plaschke K

更新日期：2016-11-01 00:00:00

abstract：:Acute blood-brain barrier (BBB) opening in cerebral ischemia is an often observed but seldom studied phenomenon. Increased permeability has been implicated with several consequences including exacerbating ischemic injury, leading to hemorrhagic transformation (HT) and also predictive of chronic damage and a way of del...

journal_title：Neurological research

authors： Nagaraja TN,Keenan KA,Brown SL,Fenstermacher JD,Knight RA

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Misery perfusion increases the risk of stroke recurrence in patients with symptomatic major cerebral artery occlusion. The ratio of brain perfusion contralateral-to-affected asymmetry in the cerebellar hemisphere to brain perfusion affected-to-contralateral asymmetry in the cerebral hemisphere ...

journal_title：Neurological research

authors： Nomura J,Ogasawara K,Saito H,Terasaki K,Matsumoto Y,Takahashi Y,Ogasawara Y,Saura H,Yoshida K,Sato Y,Kubo Y,Ogawa A

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:Neurovascular ultrasound (nUS) is widely used as a screening and monitoring tool in patients with spontaneous cervical artery dissection (sCAD). The aim of the study was to describe the sonographical course of the affected arteries in patients with a MRI-proven sCAD by repetitive nUS. METHODS:Thirty-seven co...

journal_title：Neurological research

authors： Sengelhoff C,Nebelsieck J,Nassenstein I,Maintz D,Nabavi DG,Kuhlenbaeumer G,Ringelstein EB,Dittrich R

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:In conditions with reduced glucose levels/inability of glucose utilization, ketone bodies, especially beta-hydroxybutyrate (BHB), become a major energy source in the brain. In animal models, BHB infusion shows acute beneficial effects on the hypoxic brain. The present prospective observational study is the f...

journal_title：Neurological research

authors： Pikija S,Trkulja V,Simundic AM,Vrcek E,Boskovic K,Bacani S

更新日期：2013-11-01 00:00:00

abstract：:In 75 patients with completed stroke hypervolemic haemodilution was performed for 1 day with 500 ml 6% HES 200.000/0.6-0.66 (Elohäst) to test the acute influence of application time for haemorheological changes. The patients were divided into 3 groups randomly selected: group A received the infusion for 2 hours, group...

journal_title：Neurological research

authors： Költringer P,Langsteger W,Reisecker F,Eber O

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To explore clinical features and compare of the difference between conservative treatment and surgical treatmentin prognosis of intracranial aneurysms associated with moyamoya disease (MMD). METHODS:104 patients with MMD a ssociated with intracranial aneurysms diagnosed by digital subtraction angiography (D...

journal_title：Neurological research

authors： Yan J,Lv M,Zeng E,Tang B,Xie S,Hong T

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Natalizumab is a drug with documented efficacy in relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of natalizumab has immunosuppressive properties and it is not yet investigated if treatment with natalizumab affects the immunological response to vaccination. This study aims to investig...

journal_title：Neurological research

authors： Vågberg M,Kumlin U,Svenningsson A

更新日期：2012-09-01 00:00:00

abstract：:Objective: Nowadays, retinal microvascular structures can be investigated using optical coherence tomography angiography (OCTA). We aimed to evaluate the probable vascular changes in the foveal and peripapillary regions of patients with multiple sclerosis (MS).Methods: A total of 20 patients with relapsing remitting m...

journal_title：Neurological research

authors： Ulusoy MO,Horasanlı B,Işık-Ulusoy S

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:The novel coronavirus disease (COVID-19) pandemic poses a substantial threat to the health of healthcare personnel on the front line of caring for COVID-19 patients. The Centers for Medicare and Medicaid Services previously announced that all non-essential planned surgeries and procedures should be postpon...

journal_title：Neurological research

authors： Reed LK,Wen J,Liang B,Wang X,Feng D,Huang JH

更新日期：2020-10-01 00:00:00

abstract：:The objective of this study was to investigate the effects of transplanted bone marrow mesenchymal stem cells (BMSCs) administered via internal jugular vein injection, carotid artery injection, or intraventricular transplantation for the treatment of cerebral infarction, which was modeled in rats. The neurological sco...

journal_title：Neurological research

authors： Ruan GP,Han YB,Wang TH,Xing ZG,Zhu XB,Yao X,Ruan GH,Wang JX,Pang RQ,Cai XM,He J,Zhao J,Pan XH

更新日期：2013-03-01 00:00:00

abstract：:We developed a confocal laser scanning microscope for intra-operative imaging of brain tumors using near infrared fluorescence. The quality of near infrared images of Indocyanine Green (ICG) was compared with the surgical confocal scanning (SCS) microscope and a conventional charge-coupled device (CCD) camera; we comp...

journal_title：Neurological research

authors： Sakatani K,Kashiwasake-Jibu M,Terada H,Zuo H

更新日期：2000-07-01 00:00:00

abstract：:Child patients with Moyamoya disease initially present with ischemic symptoms. However, the long-term risk of intracranial hemorrhage for childhood Moyamoya disease is unknown. Hemodynamic overload to the fragile collateral vessels has been considered to cause hemorrhage. We reviewed angiograms to evaluate the effect ...

journal_title：Neurological research

authors： Irikura K,Miyasaka Y,Kurata A,Tanaka R,Yamada M,Kan S,Fujii K

更新日期：2000-06-01 00:00:00

abstract：:Parkinson's disease (PD) the second most common age-associated progressive neurodegenerative disorder is characterized by loss of dopaminergic neurons, cytoplasmic inclusions of aggregated proteins (Lewy bodies), and neuroinflammation. The inflammation of neurons causes release of various inflammatory mediators (IFNs,...

journal_title：Neurological research

authors： Pal R,Tiwari PC,Nath R,Pant KK

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:Intracranial aneurysms (IAs) of the posterior circulation (PC) rupture more frequently and their morbidity and mortality rates are higher compared to anterior circulation. Morphological parameters such as size ratio (SR), inflow angle and parent artery geometry are believed to contribute significantly in det...

journal_title：Neurological research

authors： Tykocki T,Nauman P,Dow Enko A

更新日期：2014-08-01 00:00:00

abstract：:The etiology of multiple sclerosis (MS) remains unknown. However, both genetic and environmental factors play important roles in its pathogenesis. While demyelination of axons is a hallmark histological feature of MS, axonal and neuronal dysfunction may correlate better with clinical disability. All major immune cell ...

journal_title：Neurological research

authors： McDole J,Johnson AJ,Pirko I

更新日期：2006-04-01 00:00:00

abstract：:Cerebral blood flow (CBF), 113mIndium-DPTA, and 14C-glucose extraction were measured simultaneously in rat brain from 2 to 58 days following a thermal insult. In the early stage of a cold induced lesion (2 days), the blood-brain barrier (BBB) was disrupted with resulting leakage and diffusionary loss of both glucose a...

journal_title：Neurological research

authors： Pollay M,Stevens FA

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVES:To study whether Clopidogrel-Aspirin combined treatment for high risk transient ischaemic attack (TIA) or minor stroke results in increased number of lesions associated with anti-thrombotic cerebral haemorrhage or cerebral micro-bleeds (CMB) than aspirin alone treatment. METHODS:The patients recruited in CH...

journal_title：Neurological research

authors： Wang Z,Xu C,Wang P,Wang Y,Xin H

更新日期：2015-11-01 00:00:00