Hypervolemic haemodilution and completed stroke: how important is the application time for its effect?

abstract：:The present study aimed to examine the effects of N omega-nitro-L-arginine (LNA) on the early ischemic neuronal damage (EIND). All the experiments were carried out under general anesthesia, maintaining the blood gases and the body temperature within the physiological ranges. The local CBF, the topographically correspo...

journal_title：Neurological research

authors： Matsui T,Nagafuji T,Mori T,Asano T

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVES:In conditions with reduced glucose levels/inability of glucose utilization, ketone bodies, especially beta-hydroxybutyrate (BHB), become a major energy source in the brain. In animal models, BHB infusion shows acute beneficial effects on the hypoxic brain. The present prospective observational study is the f...

journal_title：Neurological research

authors： Pikija S,Trkulja V,Simundic AM,Vrcek E,Boskovic K,Bacani S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:High blood pressure (BP) is a major risk factor for stroke and all of its pathological subtypes including subarachnoid hemorrhage (SAH). However, there is little evidence demonstrating whether failure to have regular BP measured could result in underestimation of people at risk for SAH. Therefore, we aimed ...

journal_title：Neurological research

authors： Shiue I,Hankey GJ,Arima H,Anderson CS

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Previous reports showed the reduction of dopamine transporter immunoreactivity in peripheral blood lymphocytes in Parkinson's disease. In this work, we sought to investigate the possible correlation between central and peripheral dopamine transporter immunoreactivity values in a group of 11 drug-naive patient...

journal_title：Neurological research

authors： Buttarelli FR,Capriotti G,Pellicano C,Prosperi D,Circella A,Festa A,Giovannelli M,Tofani A,Pontieri FE,Scopinaro F

更新日期：2009-09-01 00:00:00

abstract：:The treatment of arteriovenous malformations depends on the efforts of a multidisciplinary team whose ultimate goal is to achieve better results when compared to the natural history of the pathology. The role of adjuvant treatment modalities such as radiosurgery and endovascular embolization is discussed. Treatment st...

journal_title：Neurological research

authors： de Oliveira E,Tedeschi H,Raso J

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:Brain death is a clinical diagnosis often confirmed with supplementary tests. In this study, we examined the relationship between brain death and the partial pressure of brain tissue oxygen (PbtO(2)). We hypothesized that a sustained PbtO(2) of 0 is associated with brain death. METHODS:One hundred and twent...

journal_title：Neurological research

authors： Smith ML,Counelis GJ,Maloney-Wilensky E,Stiefel MF,Donley K,LeRoux PD

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Ischemic stroke is one of the most common causes of death worldwide. Early and accurate prediction of outcome in acute ischemic stroke (AIS) is important and influences risk-optimized therapeutic strategies. We investigated the changes in high-sensitivity C-reactive protein (Hs-CRP) and homocysteine (HCY) le...

journal_title：Neurological research

authors： Tu WJ,Zhao SJ,Liu TG,Yang DG,Chen H

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Numerous studies have identified different predictors for secondary hydrocephalus after aneurysmal subarachnoid hemorrhage (SAH), although predictors regarding timing of the shunt operation have never been reported. Predictors for an early shunt, which was defined as a shunt operation performed ≤30 days after...

journal_title：Neurological research

authors： Shigematsu H,Sorimachi T,Osada T,Aoki R,Srivatanakul K,Oda S,Matsumae M

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To explore the influences of mammalian target of rapamycin (mTOR) signaling pathway on ketamine-induced apoptosis, oxidative stress and Ca2+ concentration in the hippocampal neurons of rats. METHODS:The primary hippocampal neurons isolated from fetal Sprague Dawley rats were treated with ketamine (0, 50, 100...

journal_title：Neurological research

authors： Liu FF,Zhao S,Liu P,Huo SP

更新日期：2019-01-01 00:00:00

abstract：:The aim of this study was to use quantitative microdialysis to estimate the true extracellular concentrations of glucose and lactate in minimally disturbed human brain. These values are important as criteria for microdialytical monitoring in critical care patients and for determining therapy. Microdialysis procedures ...

journal_title：Neurological research

authors： Langemann H,Alessandri B,Mendelowitsch A,Feuerstein T,Landolt H,Gratzl O

更新日期：2001-07-01 00:00:00

abstract：:We examined the microsurgical anatomy of the supratentorial subarachnoid cisterns with a surgical microscope in 20 brains prepared using the immersion technique. The adult brains were immersed in Ringer's solution and air was injected into the subarachnoid cisterns while the brains remained submerged in solution. We i...

journal_title：Neurological research

authors： Vinas FC,Fandino R,Dujovny M,Chavez V

更新日期：1994-12-01 00:00:00

abstract：:Intra-arterial thrombolysis and percutaneous angioplasty is feasible in patients with acute middle cerebral artery (MCA) occlusion limited to 6 hours post-ictus, but there are some limitations such as reocclusion or hemorrhagic complications. In this report, we describe a stent placement in the treatment of a refracto...

journal_title：Neurological research

authors： Ahn JY,Han IB,Chung SS,Chung YS,Kim SH,Yoon PH

更新日期：2006-12-01 00:00:00

abstract：:According to recent reports, malnutrition may be associated with a worse prognosis in stroke patients. The aim of this study was to determine the nutritional status of stroke patients and its impact on neurological and functional status of patients in the early post-stroke period. Our prospective study included a tota...

journal_title：Neurological research

authors： Wierzbicki K,Horyniecki M,Mamak D,Szopa M,Buchała J,Stawarz G,Florek S,Adamczyk-Sowa M

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:We evaluate the bladder volume and pressure through recording the bladder afferent activity in the sacral nerve roots in acute experiments of paraplegic dogs. These measurements are intended to report the status of the bladder and to adjust the stimulation parameters of an implantable electric stimulator. ME...

journal_title：Neurological research

authors： Saleh A,Sawan M,Elzayat EA,Corcos J,Elhilali MM

更新日期：2008-02-01 00:00:00

abstract：:A series of 15 arteriovenous malformations (AVMs) of the corpus callosum--9% of 170 intracranial AVMs admitted to the School of Medicine of the University of Rome during a 30-yr period--was studied. In all cases the lesion concerned mainly the corpus callosum, although in some it also involved the surrounding structur...

journal_title：Neurological research

authors： Guidetti B,Spallone A

更新日期：1982-01-01 00:00:00

abstract：:Recent evidence indicates that different vascular risk factors are present in Alzheimer's disease (AD) and other prevalent dementia types probably contributing to deterioration of cerebrovascular function, thus enhancing neurodegeneration and premature neuronal death due to a reduction in brain perfusion. Brain blood ...

journal_title：Neurological research

authors： Cacabelos R,Fernández-Novoa L,Lombardi V,Corzo L,Pichel V,Kubota Y

更新日期：2003-09-01 00:00:00

abstract：:The relationship between the states of spinal impact injuries and magnetically evoked electromyograms (EMGs) were studied in rats. Impact injuries to the spinal cord were induced at a depth of 0.25-2.0 mm by insertion of a cylinder tip measuring 2 mm in diameter into the lumbar vertebrae L1-L2. Magnetically induced el...

journal_title：Neurological research

authors： Chiba A,Hiruma S,Hashimoto S,Inase M

更新日期：2000-10-01 00:00:00

abstract：:We examined regional cerebral blood flow (rCBF) and oxygen metabolism (rCMRO2) in 10 patients with progressive dementia and amyotrophic lateral sclerosis (DALS), in 21 patients with classical amyotrophic lateral sclerosis without dementia (ALS), and in 17 controls. The mean rCBF and rCMRO2, especially in the anterior ...

journal_title：Neurological research

authors： Tanaka M,Ichiba T,Kondo S,Hirai S,Okamoto K

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:This study assesses the clinical outcome after early combined cranioplasty (own frozen bone) and shunt implantation (Codman-Medos programmable VP shunt) in patients with skull bone defects and cerebrospinal fluid (CSF) circulation disorders. METHOD:Medical records were reviewed retrospectively for the last 1...

journal_title：Neurological research

authors： Carvi Y Nievas MN,Höllerhage HG

更新日期：2006-03-01 00:00:00

abstract：:We postulate that severe atherosclerotic occlusion of the circle of Willis and leptomeningeal arteries is an important factor in the pathogenesis of some sporadic Alzheimer's disease (AD) cases. These arterial stenoses are complicated by an overwhelming amyloid accumulation in the walls of leptomeningeal and cortical ...

journal_title：Neurological research

authors： Kalback W,Esh C,Castaño EM,Rahman A,Kokjohn T,Luehrs DC,Sue L,Cisneros R,Gerber F,Richardson C,Bohrmann B,Walker DG,Beach TG,Roher AE

更新日期：2004-07-01 00:00:00

abstract：:Anesthesia is an essential element during the induction of ischemia/reperfusion and cerebral blood flow (CBF) measurement in most animal models. Cerebral neuroprotection and intrinsic effects on CBF afforded by anesthetics are confounding variables in those models. A new model of global forebrain ischemia/reperfusion ...

journal_title：Neurological research

authors： Melgar MA,Park H,Rafols JA,Diaz FG

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To estimate the incidence of cognitive impairment (CI) among cognitively healthy, Mexican subjects, and to evaluate the impact of demographic and vascular factors on the conversion to CI and mortality. METHODS:734 eligible subjects (aged 55 to >90 years) from a population-based sample were examined. The cog...

journal_title：Neurological research

authors： Arauz A,Alonso E,Rodríguez-Saldaña J,Reynoso-Marenco M,Benitez IT,Mayorga AM,Rodríguez-Agudelo Y,Romero AV,Cantú C

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:Elevated homocysteine level is a risk factor for ischemic stroke and associated with small vessel disease such as confluent leukoaraiosis in white and black population. We investigated the relationship between the total serum homocysteine level and ischemic stroke subtypes in Chinese population. METHODS:Thre...

journal_title：Neurological research

authors： Ma Y,Zhao X,Zhang W,Liu L,Wang Y,Fang R,Wang Y

更新日期：2010-07-01 00:00:00

abstract：:To estimate the regional perfusion pressure and possibly the stump pressure during carotid endarterectomy, cerebral blood flow (CBF) measurements including a vasodilatory test were performed preoperatively. CBF was measured by 133Xe inhalation and emission tomography. An intravenous dose of 1g acetazolamide (Diamox) w...

journal_title：Neurological research

authors： Vorstrup S,Boysen G,Brun B,Engell HC

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVES:Amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer's disease (AD), but soluble oligomeric Aβ is considered to be more potent and has been hypothesized to directly impair learning and memory. Also, evidences from some clinical studies indicated that Aβ oligomer...

journal_title：Neurological research

authors： Sharma S,Verma S,Kapoor M,Saini A,Nehru B

更新日期：2016-09-01 00:00:00

abstract：:Compromise of blood flow to the brain leads to cerebral ischemia, which if left untreated may even result in cerebral infarction. This has been the main cause of major morbidity and mortality over the years in the US and around the world. Cerebral ischemia to the posterior fossa is more critical and difficult to treat...

journal_title：Neurological research

authors： Misra M,Alp MS,Hier D,Ausman JI

更新日期：2004-01-01 00:00:00

abstract：:Excessive calcium influx has been implicated in the pathophysiology of ischemic cerebral damage. The effects of nimodipine, a calcium antagonist, on the Na(+)-K+/MG+2 ATPase activity, Ca+2/Mg+2 ATPase, lipid peroxidation, and early ultrastructural findings were examined at the acute stage of ischemia in the rat brain....

journal_title：Neurological research

authors： Ildan F,Göçer AI,Tuna M,Polat S,Kaya M,Isbir T,Cetinalp E

更新日期：2001-01-01 00:00:00

abstract：INTRODUCTION:Neurotoxic homocysteine (Hcy) is thought to be an independent risk factor for neurodegenerative diseases, including Alzheimer's disease. This study is to determine whether HT22 cells, a murine hippocampal neuronal model, can be used as an in vitro model, besides the primary neuronal cultures, to investiga...

journal_title：Neurological research

authors： Zhao Z,Lu R,Zhang B,Shen J,Yang L,Xiao S,Liu J,Suo WZ

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Many studies have analyzed the association between the catechol-O-methyltransferase (COMT) Val158Met polymorphism and Parkinson's disease (PD), which yield inconsistent results. This meta-analysis was designed to determine the possible association between the COMT Val158Met polymorphism and the risk of PD in ...

journal_title：Neurological research

authors： Wang YC,Zou YB,Xiao J,Pan CD,Jiang SD,Zheng ZJ,Yan ZR,Tang KY,Tan LM,Tang MS

更新日期：2019-04-01 00:00:00

abstract：:HEADTOME III, a high resolution PET, has been employed using 15O and 18F labelled pharmaceuticals to evaluate histological malignancy of gliomas preoperatively. PET study was applied on eighteen preoperative gliomas including two recurrent cases. Haemocirculatory and metabolic indices of regional cerebral blood flow (...

journal_title：Neurological research

authors： Mineura K,Yasuda T,Kowada M,Shishido F,Ogawa T,Uemura K

更新日期：1986-09-01 00:00:00