The role of CD8+ T-cells in lesion formation and axonal dysfunction in multiple sclerosis.

abstract：:Intra- and extracranial atherosclerotic stenosis has been shown to be associated with an increased risk of secondary stroke mortality. Advances in invasive and non-invasive imaging modalities have improved analysis of hemodynamic changes and allowed better delineation of the integrity of intracranial collateralization...

journal_title：Neurological research

authors： Ding J,Wang X

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The unified Parkinson's disease rating scale (UPDRS) is the most widely used tool to rate the severity and the stage of Parkinson's disease (PD). However, the mentation, behavior and mood (MBM) subscale of the UPDRS has received little investigation regarding its validity and sensitivity. Three items of this ...

journal_title：Neurological research

authors： Holroyd S,Currie LJ,Wooten GF

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:We tested whether repetitive magnetic stimulation (rMS) induces an afferent input to the spinocerebral tract in patients with complex regional pain syndrome (CRPS). METHODS:Cortical and spinal motor evoked potentials (cMEP and sMEP), as well as the contra- and ipsilateral silent period (cCSP and iCSP), were...

journal_title：Neurological research

authors： Krause P,Foerderreuther S,Straube A

更新日期：2005-06-01 00:00:00

abstract：:This investigation was designed to clarify the chronic effects of cardiogenic emboli on cerebral perfusion and tissue densities within remaining noninfarcted brain. Local cerebral perfusion and tissue densities were measured by xenon-contrasted CT scanning and compared by cross-sectional designs among normal volunteer...

journal_title：Neurological research

authors： Obara K,Meyer JS,Muramatsu K,Mortel KF

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:It is necessary to understand the mechanism of trigeminal neuralgia (TN) and hemifacial spasm (HFS) in order to seek for an effective noninvasive remedy. As previous studies implied that inflammatory cytokines induced by demyelination following the nerve injury may be the initiated factor causing neuropathic...

journal_title：Neurological research

authors： Liu MX,Zhong J,Xia L,Dou NN,Li ST

更新日期：2019-04-01 00:00:00

abstract：:Objective: To determine the time of dementia diagnosis, symptom intensity and to assess the comorbidities.Methods: 110 patients with dementia or mild cognitive impairment were enrolled in this retrospective study. The study group was divided into subgroups: patients with a maximum of three (S ≤ 3 n = 62) and four or m...

journal_title：Neurological research

authors： Niedziela N,Nowak MM,Lis M,Blaszkowska M,Kośmider R,Adamczyk-Sowa M

更新日期：2020-05-01 00:00:00

abstract：:A new and reproducible saccular aneurysm model has been developed at the bifurcation of the common carotid artery in rats. The details of the experimental methods and results are described. It is strongly suggested that the internal elastic lamina is a critical layer in saccular aneurysm formation, because an experime...

journal_title：Neurological research

authors： van Alphen HA,Gao YZ,Kamphorst W

更新日期：1990-12-01 00:00:00

abstract：:Induction of stress proteins is thought to be important in the protection of cells from a variety of environmental insults including heat, hypoxia and ischemia. The aim of this study was to compare the mechanism of induction of heat shock protein 72 (HSP72) in primary cultures of murine cortical astrocytes by heat and...

journal_title：Neurological research

authors： Bergeron M,Mivechi NF,Giaccia AJ,Giffard RG

更新日期：1996-02-01 00:00:00

abstract：:We developed a confocal laser scanning microscope for intra-operative imaging of brain tumors using near infrared fluorescence. The quality of near infrared images of Indocyanine Green (ICG) was compared with the surgical confocal scanning (SCS) microscope and a conventional charge-coupled device (CCD) camera; we comp...

journal_title：Neurological research

authors： Sakatani K,Kashiwasake-Jibu M,Terada H,Zuo H

更新日期：2000-07-01 00:00:00

abstract：:We assessed the effect of a novel calmodulin antagonist, DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) in a spontaneously hypertensive rat (SHR) permanent focal cerebral ischemia. In experiment I, the left middle cerebral ...

journal_title：Neurological research

authors： Takagi K,Sato T,Shirasaki Y,Narita K,Tamura A,Sano K

更新日期：2001-09-01 00:00:00

abstract：:Anesthesia is an essential element during the induction of ischemia/reperfusion and cerebral blood flow (CBF) measurement in most animal models. Cerebral neuroprotection and intrinsic effects on CBF afforded by anesthetics are confounding variables in those models. A new model of global forebrain ischemia/reperfusion ...

journal_title：Neurological research

authors： Melgar MA,Park H,Rafols JA,Diaz FG

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:We have investigated whether magnetic stimulation of the sural nerve can evoke a flexor reflex recorded from the ipsilateral short head of the biceps femoris muscle. METHODS:The sural nerve was subjected to magnetic stimulation as well as by single-pulse electrical stimulation in healthy subjects. RESULTS:...

journal_title：Neurological research

authors： Kizilay F,Bilgen R,Aydin Gungor H,Uysal H,Ertekin C

更新日期：2011-07-01 00:00:00

abstract：:The influence of acidic fibroblast growth factor (aFGF) on sleep was studied in conscious rabbits. An intravenous (i.v.) bolus injection of aFGF induced a significant increase in sleep duration in comparison with animals that received vehicle solution. Somnogenic effects were obtained 30 min following i.v. aFGF admini...

journal_title：Neurological research

authors： Galan JM,Cuevas B,Dujovny N,Giménez-Gallego G,Cuevas P

更新日期：1996-12-01 00:00:00

abstract：:In addition to its possible role as a replacement source in CNS degenerative diseases, neural transplantation may be used to augment the normal production of neuroactive substances. Our laboratory at the University of Illinois at Chicago has shown, in both acute and chronic pain models, that transplantation of adrenal...

journal_title：Neurological research

authors： Pappas GD,Lazorthes Y,Bès JC,Tafani M,Winnie AP

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of etomidate, ketamine, phenytoin, and phenytoin/midazolam in a mouse model of acute cocaine toxicity. METHODS:We performed a randomized controlled study consisting of five groups (n = 25 each) of rats that received intraperitoneal injections of normal saline solution, 5 mg/kg ketamin...

journal_title：Neurological research

authors： Erdur B,Degirmenci E,Kortunay S,Yuksel A,Seyit M,Ergin A

更新日期：2012-12-01 00:00:00

abstract：:Our goal was to clarify the optimum management of the inaccessible unruptured giant and large aneurysms of the internal carotid artery (ICA). Since 1981, we have treated 18 patients with unclippable unruptured giant or large aneurysms of the ICA. Aneurysms were classified as either intracavernous or intradural. We per...

journal_title：Neurological research

authors： Kaminogo M,Kitagawa N,Takahata H,Matsuo Y,Hayashi K,Yoshioka T,Shibata S

更新日期：2001-06-01 00:00:00

abstract：:The effects of long-term administration of fructose-added glycerol solution (Glyceol): 10% glycerol, 5% fructose, 0.9% sodium chloride; 600-2000 ml/d intravenously for 7-63 d) were evaluated in a multi-institutional trial involving 1346 cases. Improvement of the neurological signs and symptoms of elevated intracranial...

journal_title：Neurological research

authors： Tsubokawa T,Katayama Y,Ishii S

更新日期：1989-12-01 00:00:00

abstract：:Decreased metabolic rate may precede cognitive impairment in Alzheimer's disease (AD) and is thus an early occurring hallmark. Several observations in post-mortem brain indicate that activated neurons are better able to withstand aging and AD, a phenomenon paraphrased by us as 'use it or lose it'. Moreover, a number o...

journal_title：Neurological research

authors： Swaab DF

更新日期：2003-09-01 00:00:00

abstract：:An approach to aneurysms arising at the bifurcation of the basilar artery and its neighborhood is described. The temporal pole of the nondominant side is retracted posteriorly to provide a wide operative field and a better view of aneurysms. ...

journal_title：Neurological research

authors： Sano K

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:We evaluate the bladder volume and pressure through recording the bladder afferent activity in the sacral nerve roots in acute experiments of paraplegic dogs. These measurements are intended to report the status of the bladder and to adjust the stimulation parameters of an implantable electric stimulator. ME...

journal_title：Neurological research

authors： Saleh A,Sawan M,Elzayat EA,Corcos J,Elhilali MM

更新日期：2008-02-01 00:00:00

abstract：:Treatment modalities for metastatic spine disease have significantly expanded over the last two decades. This expansion occurred in many different fields. Improvement in surgical techniques and instrumentation now allow the oncologic spine surgeons to effectively circumferentially decompress the neural elements withou...

journal_title：Neurological research

authors： Dea N,Fisher CG

更新日期：2014-06-01 00:00:00

abstract：:A case is reported of intractable epilepsy associated with a hypothalamic hamartoma in an 18 year old man. The patient underwent a two-third anterior callsotomy and, subsequently, removal of the hamartoma. Callosotomy did not affect the generalized seizure pattern. The authors believe this to be the first documented c...

journal_title：Neurological research

authors： Pallini R,Bozzini V,Colicchio G,Lauretti L,Scerrati M,Rossi GF

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVES:Hourly neurologic assessments for traumatic brain injury (TBI) in the critical care setting are common practice but prolonged use may actually be harming patients through sleep deprivation. We reviewed practice patterns at our institution in order to gain insight into the role of frequent neurological assess...

journal_title：Neurological research

authors： Stone JJ,Childs S,Smith LE,Battin M,Papadakos PJ,Huang JH

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:Recent studies have suggested that rehabilitation therapy can accelerate functional recovery after a stroke. Although often overlooked, the cortical hemisphere contralateral to an infarction plays an important role. This study investigates alterations in metabolism of both the damaged ('ipsilateral') as well...

journal_title：Neurological research

authors： Jiang XF,Zhang T,Sy C,Nie BB,Hu XY,Ding Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:High-sensitivity C-reactive protein (hs-CRP) is an inflammatory marker that is associated with the outcomes of ischemic stroke. However, the role of hs-CRP levels in the functional outcomes after large-artery atherosclerosis (LAA) and small-artery occlusion (SAO) is poorly understood. METHODS:We recruited 1...

journal_title：Neurological research

authors： Hou D,Liu J,Feng R,Gao Y,Wang Y,Wu J

更新日期：2017-11-01 00:00:00

abstract：:OBJECTIVE: To explore the neural substrates of implicit self-esteem in university students. METHODS: The subjects comprised four females and six males (aged 20-25 years). They were asked to finish the implicit association test (IAT) for implicit self-esteem while brain electrical activity was recorded at 64 scalp site...

journal_title：Neurological research

authors： Yang J,Zhang Q

更新日期：2009-07-08 00:00:00

abstract：:It is known that mitochondrial ATP-sensitive potassium channels (mitoKATP) play a significant role in protecting cerebral function from ischemia-reperfusion injury, which is related with a decrease in the mitochondrial matrix calcium. However, the effect of mitochondrial calcium uniporter (MCU) on diazoxide-induced ce...

journal_title：Neurological research

authors： Zhang L,Wang S,Dong H,Li Y,Wang P,Li S,Guo Y,Yao R

更新日期：2014-07-01 00:00:00

abstract：:To study the pathophysiology of olivopontocerebellar atrophy (OPCA), we destroyed inferior olive nuclei of male Wistar rats using 3-acetyl pyridine (3-AP) + harmaline + niacinamide. These rats showed a sluggish and ataxic gait. To elucidate the relationship between thyrotropin releasing hormone (TRH) in the Purkinje c...

journal_title：Neurological research

authors： Adachi K,Rhue BN,Li M,Izumi M,Osano H,Mitsuma T

更新日期：2000-06-01 00:00:00

abstract：:The aim of this study was to use quantitative microdialysis to estimate the true extracellular concentrations of glucose and lactate in minimally disturbed human brain. These values are important as criteria for microdialytical monitoring in critical care patients and for determining therapy. Microdialysis procedures ...

journal_title：Neurological research

authors： Langemann H,Alessandri B,Mendelowitsch A,Feuerstein T,Landolt H,Gratzl O

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:One of the main obstacles of electrode implantation in epilepsy surgery is the electrode shift between implantation and the day of explantation. We evaluated this possible electrode displacement using intraoperative MRI (iopMRI) data and CT/MRI reconstruction. METHODS:Thirteen patients (nine female, four ma...

journal_title：Neurological research

authors： Sommer B,Rampp S,Doerfler A,Stefan H,Hamer HM,Buchfelder M,Roessler K

更新日期：2018-10-01 00:00:00