Abstract:
OBJECTIVE:Neurovascular ultrasound (nUS) is widely used as a screening and monitoring tool in patients with spontaneous cervical artery dissection (sCAD). The aim of the study was to describe the sonographical course of the affected arteries in patients with a MRI-proven sCAD by repetitive nUS. METHODS:Thirty-seven consecutive patients aged<60 years with 1.5 T MRI-proven sCAD were prospectively investigated by nUS, and within 48 hours after admission before MRI. The patients were re-investigated after 6 months and again after a period>12 months. RESULTS:Forty-nine sCAD were detected in 37 patients; 24 lesions (49%) were located in the internal carotid arteries (ICA), and 25 (51%) in the vertebral arteries (VA). An arterial occlusion was found in 13 arteries (27%). The recanalization rate of occluded arteries was 62%. Regression of stenosis/occlusion within the first 6 months was found in 34 (69%) of the affected arteries, while between 6 and >12 months, the improvement rate was lower (19%). A complete recanalization without residual stenosis after 6 months was found in 39%. In only one artery, initial high grade ICA stenosis progressed to complete persistent occlusion (2%). DISCUSSION:The course of arterial stenosis or occlusion caused by sCAD is highly dynamic during the first 6 month after the event. The vast majority of arteries show regression of stenosis or recanalization of initial occlusion. Only a minority of patients experience a persistent deterioration of the vessel status.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Sengelhoff C,Nebelsieck J,Nassenstein I,Maintz D,Nabavi DG,Kuhlenbaeumer G,Ringelstein EB,Dittrich Rdoi
10.1179/174313208X319080subject
Has Abstractpub_date
2008-09-01 00:00:00pages
687-9issue
7eissn
0161-6412issn
1743-1328journal_volume
30pub_type
杂志文章abstract:OBJECTIVES:Microglial cells in spinal dorsal horn can be activated by nociceptive stimuli and the activated microglial cells release various cytokines enhancing the nociceptive transmission. However, the mechanisms underlying the activation of spinal microglia during nociceptive stimuli have not been well understood. I...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2017.1281198
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:It has been suggested that metalloproteinase-9 (MMP-9) could predict the onset of cerebral vasospasm after subarachnoidal haemorrhage (SAH). The aim of this study was to analyse, in patients with SAH, the difference between patients with MRI ischaemic infarcts and patients without, and to investigate the rol...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132815Y.0000000045
更新日期:2015-08-01 00:00:00
abstract::Neuronal nitric oxide synthase (nNOS) regulates neurogenesis in normal developing brain, but the role of nNOS in neurogenesis in the ischemic brain remains unclear. To investigate the temporal and spatial relationship between cell proliferation of the ependymal/subventricular zone (SVZ), a principal neuroproliferative...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164106X91942
更新日期:2006-01-01 00:00:00
abstract::No marker that predicts accurately the time of occurrence of cerebral vasospasm due to subarachnoid hemorrhage (SAH) has been reported. In the present study, membrane-bound tissue factor (mTF) and myelin basic protein (MBP) concentrations in cerebrospinal fluid (CSF) were evaluated as a predictor of the time of occurr...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199225
更新日期:2001-10-01 00:00:00
abstract::A new and reproducible saccular aneurysm model has been developed at the bifurcation of the common carotid artery in rats. The details of the experimental methods and results are described. It is strongly suggested that the internal elastic lamina is a critical layer in saccular aneurysm formation, because an experime...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1990.11739953
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVES:To explore clinical features and compare of the difference between conservative treatment and surgical treatmentin prognosis of intracranial aneurysms associated with moyamoya disease (MMD). METHODS:104 patients with MMD a ssociated with intracranial aneurysms diagnosed by digital subtraction angiography (D...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1773663
更新日期:2020-09-01 00:00:00
abstract::The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum sampl...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1080/01616412.1998.11740573
更新日期:1998-10-01 00:00:00
abstract::Nerve growth factor (NGF) synthesis in cultured mouse L-M fibroblast and astroglial cells can be increased after the treatment with L-threo-3,4-dihydroxyphenylserine (DOPS). Since the increase of NGF is not blocked by the treatment with decarboxylase inhibitor, DOPS may have direct effect to increase the NGF content. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1994.11740227
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVES:Surgical management of tumors in the sacropelvic region is a challenging field of spine surgery because of the region's complex local anatomy and biomechanics. Recent developments in anesthesia and intensive care have allowed us to perform extended surgeries focused on the en bloc resection of sacropelvic tu...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/1743132814Y.0000000370
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:Equestrian sports can result in a variety of injuries to the nervous system due to many factors. We describe our series of 80 patients with injuries sustained during participation in equestrian sports. METHODS AND RESULTS:All patients seen at the regional trauma center with injuries associated with equestri...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132814Y.0000000373
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:One of the main obstacles of electrode implantation in epilepsy surgery is the electrode shift between implantation and the day of explantation. We evaluated this possible electrode displacement using intraoperative MRI (iopMRI) data and CT/MRI reconstruction. METHODS:Thirteen patients (nine female, four ma...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2018.1484588
更新日期:2018-10-01 00:00:00
abstract::Acute presentation of Type I Chiari malformation in children is distinctly rare. An 11 year old male suffered a trauma to the right temporal-parietal region in a tobogganing accident resulting in an open depressed skull fracture. Radiographic evaluation included a Computed Tomographic scan which also demonstrated a si...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740599
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:We evaluate the bladder volume and pressure through recording the bladder afferent activity in the sacral nerve roots in acute experiments of paraplegic dogs. These measurements are intended to report the status of the bladder and to adjust the stimulation parameters of an implantable electric stimulator. ME...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164108X268250
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Diffusion tensor tractography (DTT) has recently been shown to accurately detect nerve injury and regeneration. This study assesses whether 7-tesla (7T) DTT imaging is a viable modality to observe axonal outgrowth in a 4 cm rabbit sciatic nerve injury model fixed by a reverse autograft (RA) surgical techniqu...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2018.1554284
更新日期:2019-03-01 00:00:00
abstract::Supraventricular and ventricular tachyarrhythmia are established causes of syncope. We investigated the mean blood flow velocities (Vmean) of the middle cerebral arteries (MCA) during routine cardiac electrophysiologic studies in patients with supraventricular and ventricular tachyarrhythmias in order to evaluate the ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740555
更新日期:1998-09-01 00:00:00
abstract::Until recently, endovascular management of intracranial aneurysms has focused on mechanical and hemodynamic aspects: characterizing aneurysm morphology by angiogram, mechanical obstruction by detachable coils, and flow diversion with endovascular stents. Although now common practice, these interventions only ward off ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/1743132814Y.0000000435
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:The study objectives are (1) to identify factors predicting the excellent visual recovery after transsphenoidal removal of pituitary tumors and (2) to describe the association of excellent visual recovery and early restoration of symmetry of the decompressed optic chiasm. METHODS:Thirty-five patients with v...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132814Y.0000000407
更新日期:2015-01-01 00:00:00
abstract::Despite the accumulation of intraoperative data on arteriovenous malformations (AVMs), details of the haemodynamics have not yet been elucidated. A hydraulic model was constructed from silicone and glass tubes to simulate a high-flow AVM. During stepwise obliteration of the nidus, haemodynamic changes were continuousl...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1993.11740174
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVE:Cerebral small vessel disease (CSVD) describes a syndrome of neuroimaging, pathological, and associated clinical features caused by small intracranial vascular lesions, which commonly coexists with large artery atherosclerosis (LAA) and has been identified as a major cause of motor impairment over time. In th...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1080/01616412.2018.1446283
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To assess the effect of sensory nerve stimulation in older people with peripheral neuropathy associated with diabetes (DPN). MATERIALS AND METHODS:A randomized, placebo controlled, double blind trial was used to assess the effect of 12 weeks of low frequency sensory nerve stimulation (LF-SNS) in the lower li...
journal_title:Neurological research
pub_type: 杂志文章,随机对照试验
doi:10.1179/016164107X208095
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:Elevated homocysteine level is a risk factor for ischemic stroke and associated with small vessel disease such as confluent leukoaraiosis in white and black population. We investigated the relationship between the total serum homocysteine level and ischemic stroke subtypes in Chinese population. METHODS:Thre...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164109X12445616596445
更新日期:2010-07-01 00:00:00
abstract::Thirty outpatients with unruptured cerebral aneurysms screened by computed angiotomography have been analysed and followed up in our clinic since 1979. Seventeen were men and the age range was 41 to 74 years old (mean 57.7 years). Patients had no or only mild neurological symptoms, such as headache, sensorimotor or sp...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1986.11739736
更新日期:1986-06-01 00:00:00
abstract:INTRODUCTION:Alzheimer's disease (AD) is the most common neurodegenerative disease across the world. The major cause of AD is extensive oxidative stress and inflammation in central nervous system (CNS). Vitamin D3 and E are the most known vitamins that control oxidative stress and mitochondrial respiratory function. Th...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1787624
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:Although magnesium is a well-known treatment for vasospasm following subarachnoid hemorrhage, its mechanism of action for cerebral vascular relaxation is not clear. In addition, it is known that L-type calcium (Ca(2+)) channels play a pivotal role in smooth muscle contraction. To investigate the role of L-t...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000016
更新日期:2012-04-01 00:00:00
abstract::This article covers the basis of tethered cord syndrome as a stretch-induced spinal cord disorder, including pathophysiology, signs and symptoms, imaging diagnosis, indication for surgical treatment, and surgical procedures. Anomalies that cause mechanical spinal cord tethering are listed, and the surgical untethering...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164104225017947
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To investigate the perfusion parameters of computed tomography (CT) in hypoxicischemic encephalopathy (HIE) after off-pump coronary artery bypass grafting (OPCABG), and its potential in predicting the occurrence and prognosis of hypoxic-ischemic encephalopathy. METHODS:We selected 830 patients. The patients ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2017.1315862
更新日期:2017-06-01 00:00:00
abstract::There have been reports that superior cervical ganglionectomy (SCG) is effective as a treatment for cerebral vasospasm following subarachnoid haemorrhage (SAH). On the other hand, denervation supersensitivity is supposed to play an important role in vasospasm. The two accounts contradict each other. To investigate thi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1988.11739836
更新日期:1988-09-01 00:00:00
abstract:OBJECTIVES:Cerebral hypoxia-ischemia leads to the depletion of ATP. Hypoxanthine, a degradation product of ATP, can be salvaged by hypoxanthine phosphoribosyl transferase (HPRT) and used to reform high-energy purines. Hypothermia conserves ATP in hypoxia-ischemia, possibly by preserving HPRT activity. We hypothesized t...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X49229
更新日期:2006-12-01 00:00:00
abstract::A computer software program (Seapit) was developed for precise determination of intracranial targets identified by stereotactic computed tomography (CT). This program was added to the software of a GE 8800 CT scanner to perform the following operations: millimetre precise calculation and display of the rectilinear coo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1987.11739781
更新日期:1987-06-01 00:00:00
abstract:INTRODUCTION:Here, we investigated inflammatory signs of peripheral nerves in leptin-deficient obese ob/ob mice and the modulating effects of the exogenous iron load. METHODS:Ob/ob and ob/+ control mice were fed with high, standard, or low iron diet for four months. RESULTS:We found intraepidermal nerve fiber degener...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2018.1564191
更新日期:2019-04-01 00:00:00