The effect of normothermic and hypothermic hypoxia-ischemia on brain hypoxanthine phosphoribosyl transferase activity.

abstract：OBJECTIVES:Hourly neurologic assessments for traumatic brain injury (TBI) in the critical care setting are common practice but prolonged use may actually be harming patients through sleep deprivation. We reviewed practice patterns at our institution in order to gain insight into the role of frequent neurological assess...

journal_title：Neurological research

authors： Stone JJ,Childs S,Smith LE,Battin M,Papadakos PJ,Huang JH

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:The actual relationship between neural stem cells and SDF-1alpha/CXCR4 after brain injury has not yet been elucidated, although recent studies have speculated that stromal cell-derived factor-1alpha (SDF-1alpha) and its receptor, CXCR4, could contribute to neural stem cells migration after brain injury. In th...

journal_title：Neurological research

authors： Itoh T,Satou T,Ishida H,Nishida S,Tsubaki M,Hashimoto S,Ito H

更新日期：2009-02-01 00:00:00

abstract：:The endothelial lining of blood vessels plays an important role in the control of arterial tone by releasing a number of vasoactive factors. Among these, nitric oxide (NO) or a NO containing moiety, some cyclooxygenase products such as prostacyclin (PGl2) and a still hypothetical hyperpolarizing factor may induce dila...

journal_title：Neurological research

authors： Mackert JL,Parsons AA,Wahl M,Schilling L

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVES:There is no definitive data regarding the usefulness of Brain microbleeds (BMBs) as an imaging marker with homeostatic markers to predict intracerebral hemorrhage (ICH) and ischemic stroke risk to personalize decisions on anticoagulation in AF. In this study, we prospectively evaluated clinical, radiological...

journal_title：Neurological research

authors： Altintas O,Niftaliyev E,Asil T

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To assess the effect of sensory nerve stimulation in older people with peripheral neuropathy associated with diabetes (DPN). MATERIALS AND METHODS:A randomized, placebo controlled, double blind trial was used to assess the effect of 12 weeks of low frequency sensory nerve stimulation (LF-SNS) in the lower li...

journal_title：Neurological research

authors： Khalil Z,Ogrin R,Darzins PJ

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:Cerebral small vessel disease (CSVD) describes a syndrome of neuroimaging, pathological, and associated clinical features caused by small intracranial vascular lesions, which commonly coexists with large artery atherosclerosis (LAA) and has been identified as a major cause of motor impairment over time. In th...

journal_title：Neurological research

authors： Zhu H,Li Z,Lv J,Zhao R

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Alteration of sensorium or an encephalopathy is a common diagnostic dilemma in critically ill patients and can be caused by a number of conditions. Sepsis associated encephalopathy (SAE) is now the most common encephalopathy encountered among intensive care unit (ICU) patients. DEFINITIONS:SAE is an encep...

journal_title：Neurological research

authors： Maramattom BV

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:We reviewed our most recent work on the protective effect of adenosine A(2A)antagonism in cerebral ischemia. METHODS:Focal ischemia was produced in rats by introducing a nylon monofilament pre-coated with silicone through the external carotid artery to occlude the right MCA at its origin. RESULTS:A(2A) ant...

journal_title：Neurological research

authors： Pedata F,Gianfriddo M,Turchi D,Melani A

更新日期：2005-03-01 00:00:00

abstract：:1-Aminocyclopropanecarboxylic acid is a high affinity ligand with partial agonist properties at strychnine-insensitive glycine sites associated with the N-methyl-D-aspartate subtype of glutamate receptors. Since occupation of these sites appears required for operation of N-methyl-D-aspartate, receptor coupled cation c...

journal_title：Neurological research

authors： Fossom LH,Von Lubitz DK,Lin RC,Skolnick P

更新日期：1995-08-01 00:00:00

abstract：:In this work, we evaluated the differences between epileptic electroencephalogram (EEG) and interictal EEG by computing some non-linear features. Correlation dimension (CD) and Hurst exponent (H) were calculated for 100 segments of epileptic EEG and 100 segments of interictal EEG. A comparison was made between epilept...

journal_title：Neurological research

authors： Geng S,Zhou W,Yuan Q,Cai D,Zeng Y

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:In about 10% of glioblastoma patients, preoperative MRI discloses the presence of tumor cysts. Whereas the impact of cystic appearance on prognosis has been discussed extensively, only little is known about the tumor cyst fluid. In this study, we tested the feasibility of the surface enhanced laser desorptio...

journal_title：Neurological research

authors： Hoelscher M,Richter N,Melle C,von Eggeling F,Schaenzer A,Nestler U

更新日期：2013-12-01 00:00:00

abstract：INTRODUCTION:Cocaine- and amphetamine-regulated transcript (CART) peptide has been demonstrated to exert neuroprotective effects in stroke and some neurodegeneration diseases. In current study, we investigated the protective effects and underlying mechanisms of CART in APP/PS1 mice. METHODS:The protein levels of CART,...

journal_title：Neurological research

authors： Yin K,Jin J,Zhu X,Yu L,Wang S,Qian L,Han L,Xu Y

更新日期：2017-10-01 00:00:00

abstract：:Objective: To assess the neuropsychological status of pediatric multiple sclerosis (MS) patients and its relationship with clinical variables in a longitudinal study.Methods: Patients with MS (n = 46) and age- and gender-matched healthy control subjects (HCs, n = 53) were given tests of non-verbal reasoning, attention...

journal_title：Neurological research

authors： Öztürk Z,Gücüyener K,Soysal Ş,Konuşkan GD,Konuşkan B,Dikmen AU,Anlar B

更新日期：2020-02-01 00:00:00

abstract：INTRODUCTION:Cerebrospinal fluid (CSF) oligoclonal bands (OB) imply intrathecal immunoglobulin synthesis and B-cell immune process. There is scarce evidence of OB having a role in disease prognosis. The objective of the present study was to determine OB's prognostic value regarding disease progression. METHODS:Betwee...

journal_title：Neurological research

authors： Rojas JI,Tizio S,Patrucco L,Cristiano E

更新日期：2012-11-01 00:00:00

abstract：:Objective: The protective effects of 2%-4% hydrogen gas in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) have been previously reported. This study aimed to assess the neuroprotective effects of high concentration hydrogen (HCH) on DEACMP.Methods: A total of 36 male Sprague-Dawley rats were divi...

journal_title：Neurological research

authors： Shen M,Zheng Y,Zhu K,Cai Z,Liu W,Sun X,Liu J,Zhu D

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Transient ischemic attack (TIA) with carotid artery disease (CAD) can increase the risk of cognitive decline. However, the neural mechanisms of the disorder remain unclear. The aim of this study was, using diffusion tensor imaging (DTI), to detect microstructural changes in patients with symptomatic CAD pres...

journal_title：Neurological research

authors： Guo J,Wang S,Li R,Chen N,Zhou M,Chen H,Gong Q,He L

更新日期：2014-01-01 00:00:00

abstract：:A new suction device for microneurosurgery is presented. A surgical cottonoid is covered with a polyethylene film so that vacuum power is maintained throughout the length of the cottonoid. One end is connected to a vacuum pump via a plastic tube. Five to 10 mm of the surgical cottonoid are exposed for suctioning at th...

journal_title：Neurological research

authors： Sakatani K,Zuo H

更新日期：1998-09-01 00:00:00

abstract：:From 118 transsphenoidally operated patients, 100 had a pituitary adenoma; 33 prolactinomas, 20 HGH-producing, 2 ACTH-producing and 45 inactive adenomas. The first transsphenoidal operation did not cause any mortality; after reoperation for suspected recurrence on follow-up, 2 patients died; thus, the global managemen...

journal_title：Neurological research

authors： Auer LM,Clarici G

更新日期：1985-09-01 00:00:00

abstract：:Cerebral blood flow (CBF), 113mIndium-DPTA, and 14C-glucose extraction were measured simultaneously in rat brain from 2 to 58 days following a thermal insult. In the early stage of a cold induced lesion (2 days), the blood-brain barrier (BBB) was disrupted with resulting leakage and diffusionary loss of both glucose a...

journal_title：Neurological research

authors： Pollay M,Stevens FA

更新日期：1980-01-01 00:00:00

abstract：:Microsurgical anatomy for the pterional approach was studied regarding the origin and the course of the ophthalmic artery and the distal dural ring using human cadaveric specimens, with special reference to the surrounding bony structures. In 50 human adult formalin-fixed cadaveric cerebral hemispheres and 10 block sp...

journal_title：Neurological research

authors： Hokama M,Hongo K,Gibo H,Kyoshima K,Kobayashi S

更新日期：2001-06-01 00:00:00

abstract：:Excessive calcium influx has been implicated in the pathophysiology of ischemic cerebral damage. The effects of nimodipine, a calcium antagonist, on the Na(+)-K+/MG+2 ATPase activity, Ca+2/Mg+2 ATPase, lipid peroxidation, and early ultrastructural findings were examined at the acute stage of ischemia in the rat brain....

journal_title：Neurological research

authors： Ildan F,Göçer AI,Tuna M,Polat S,Kaya M,Isbir T,Cetinalp E

更新日期：2001-01-01 00:00:00

abstract：:The objective of this study was to improve the ability to detect cerebrovascular complications in patients undergoing complicated neurosurgical procedures using on-line monitoring of cerebral pH with in vivo microdialysis. We employed on-line pH monitoring in patients with a variety of neurosurgical procedures includi...

journal_title：Neurological research

authors： Mendelowitsch A,Sekhar LN,Caputy AJ,Shuaib A

更新日期：1998-03-01 00:00:00

abstract：:This paper reviews our recent studies of the role of cortical spreading depression (CSD) in the pathogenesis of brain disorders. Our investigation is a computational one, involving the development and utilization of a complex neuro-metabolic model of the interactions assumed to occur in the cortex during the passage o...

journal_title：Neurological research

authors： Ruppin E,Reggia JA

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the effects of oral administration of a novel benzodiazepine derivative, JM-20, on the neurological behavior of different rodent models, focusing on the GABAergic effect. We have also investigated the acute toxicity of oral administration of JM-20 in mice. METHODS:Mi...

journal_title：Neurological research

authors： Figueredo YN,Rodríguez EO,Reyes YV,Domínguez CC,Parra AL,Sánchez JR,Hernández RD,Verdecia MP,Pardo Andreu GL

更新日期：2013-10-01 00:00:00

abstract：:Using magnetic resonance imaging, we reviewed 141 infratentorial infarcts in 81 consecutive cases: 65 infarcts were seen in the paramedian pons, while 18 in the posterior inferior cerebellar artery (PICA) territory and 17 in the watershed area between PICA and superior cerebellar artery. No comparable sign or symptom ...

journal_title：Neurological research

authors： Yin WM,Nagata K,Satoh Y,Yokoyama E,Watahiki Y,Yuya H,Hirata Y,Ogawa T,Inugami A

更新日期：1994-06-01 00:00:00

abstract：:The effects of long-term administration of fructose-added glycerol solution (Glyceol): 10% glycerol, 5% fructose, 0.9% sodium chloride; 600-2000 ml/d intravenously for 7-63 d) were evaluated in a multi-institutional trial involving 1346 cases. Improvement of the neurological signs and symptoms of elevated intracranial...

journal_title：Neurological research

authors： Tsubokawa T,Katayama Y,Ishii S

更新日期：1989-12-01 00:00:00

abstract：:The effects of etomidate on focal cerebral ischaemia following transorbital occlusion of the cat middle cerebral artery were investigated. Etomidate had no effect on CBF before or after onset of ischaemia by comparison with controls, but caused a greater fall in CBF in cats with high preocclusion or initial ischaemic ...

journal_title：Neurological research

authors： Venables GS,Strong AJ,Miller SA,Gibson G,Hardy JA

更新日期：1986-12-01 00:00:00

abstract：:This study was performed to test whether GYKI 52466, a nonNMDA receptor antagonist, would improve microregional oxygen supply and consumption balance in the focal cerebral ischemic area. Rats were anesthetized with 1.4% isoflurane. For the GYKI Group (n = 8), 10 min before middle cerebral artery (MCA) occlusion, a bol...

journal_title：Neurological research

authors： Chi OZ,Chang Q,Wang G,Liu X,Weiss HR

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:It is not fully understood how the stimulus/response curves obtained by transcranial magnetic stimulation (TMS) reflect the function of the cortico-motoneuronal (CM) and spinal motoneuronal (SM) systems in healthy subjects. To understand these response functions, we studied patients with amyotrophic lateral s...

journal_title：Neurological research

authors： Oishi A,Tobimatsu S,Ogata K,Taniwaki T,Kinukawa N,Toyoshiba H,Kira J

更新日期：2008-12-01 00:00:00

abstract：:It is known that mitochondrial ATP-sensitive potassium channels (mitoKATP) play a significant role in protecting cerebral function from ischemia-reperfusion injury, which is related with a decrease in the mitochondrial matrix calcium. However, the effect of mitochondrial calcium uniporter (MCU) on diazoxide-induced ce...

journal_title：Neurological research

authors： Zhang L,Wang S,Dong H,Li Y,Wang P,Li S,Guo Y,Yao R

更新日期：2014-07-01 00:00:00