Abstract:
:Despite results linking shift work with ill health, only a few studies have addressed its relation with mortality. The purpose of the present study was to examine the hypothesis that shift work is a predictor of mortality. The study involved a sample of 22,411 individuals of the Swedish population. Data were obtained through annual phone interviews done between 1979 and 2000. Cox regression analysis was used to assess the association between shift work/day work as the independent variable and death/survival during the subsequent years as the dependent variable. Separate analyses were carried out for female and male white- and blue-collar workers, respectively. The results were adjusted for age, stress, physical work load, disease at the outset of the study, and smoking. Mortality was significantly increased for female white-collar workers, with a Hazard Ratio of 2.61 and a 95% confidence interval of 1.26-5.41. No other significant effects were found. It is concluded that blue-collar shift work is not related to mortality, but that risk of death is increased for women white-collar shift workers compared to women white-collar day workers.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Akerstedt T,Kecklund G,Johansson SEdoi
10.1081/cbi-200038520subject
Has Abstractpub_date
2004-01-01 00:00:00pages
1055-61issue
6eissn
0742-0528issn
1525-6073journal_volume
21pub_type
杂志文章abstract::A double-blind randomized parallel-group trial was undertaken to evaluate the influence of the dosing time of sustained-release ketoprofen (SRK) on its acceptability and efficacy. The SRK was prescribed for 2 weeks (200 mg once a day) to 117 outpatients with osteoarthritis of the knee and/or hip. One group received SR...
journal_title:Chronobiology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/07420529409055898
更新日期:1994-04-01 00:00:00
abstract::This study investigates if the serotoninergic system plays a role in chronotoxic effects of the anticancer agent oxaliplatin (l-OHP). Four groups of female rats (120 in total) synchronized with light-dark (12 h:12 h) were treated with: (i) saline, (ii) para-chlorophenylalanine (pCPA, an inhibitor of serotonin biosynth...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120015957
更新日期:2002-11-01 00:00:00
abstract::Treatment-related changes in neurobiological rhythms are of increasing interest to psychologists, psychiatrists, and biological rhythms researchers. New methods for analyzing change in rhythms are needed, as most common methods disregard the rich complexity of biological processes. Large time series data sets reflect ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520902772221
更新日期:2009-02-01 00:00:00
abstract::Disruption of circadian rhythms, which frequently occurs during night shift work, may be associated with cancer progression. The effect of chronotype (preference for behaviors such as sleep, work, or exercise to occur at particular times of day, with an associated difference in circadian physiology) and alignment of b...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2013.842575
更新日期:2014-03-01 00:00:00
abstract::The pineal hormone melatonin is potentially useful in the treatment of disorders, especially sleep disorders, associated with circadian rhythm disturbance. We have examined its effects on sleep, mood, and behaviour in a double-blind, placebo-controlled study of a small group of police officers working spans of seven s...
journal_title:Chronobiology international
pub_type: 临床试验,杂志文章
doi:10.3109/07420529309064485
更新日期:1993-10-01 00:00:00
abstract::Nineteen adult cancer patients each received 6-10 monthly treatments of doxorubicin and cisplatin. For 24-30 hr before each treatment, recumbent pulse was measured. Treatment was stopped for disease progression or when a total doxorubicin dose of 550 mg/m2 was reached. No patient developed congestive heart failure (CH...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528409059119
更新日期:1984-01-01 00:00:00
abstract::The effects of Chagas disease on the mammalian circadian system were studied in Trypanosoma cruzi-infected C57-B16J mice. Animals were inoculated with CAI or RA strains of T. cruzi or vehicle, parasitism confirmed by blood specimen visualization and locomotor activity rhythms analyzed by wheel-running recording. RA-st...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120017687
更新日期:2003-01-01 00:00:00
abstract::Bone sarcomatous cells derived from human malignant tumors were cultured. The mitotic index was recorded for 39 hr. When the cultured cells originated from patients with cancer disease before any chemotherapy, ultradian mitotic rhythms of a 6-9-hr period were detected, but in many cases only after a sensitive statisti...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528909064628
更新日期:1989-01-01 00:00:00
abstract::In this study, we aimed to show how age affects hibernation in the Syrian hamster. Experimentally, we used 30 male animals differing in age. The old animals were 20 months of age and the adults were 8 months of age at the end of the test. The young animals were 3 weeks old at the start of testing and 5 months old at t...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100101069
更新日期:2000-09-01 00:00:00
abstract::A number of Djungarian hamsters (Phodopus sungorus) of our institute show activity patterns that seem incompatible with proper adjustment to a periodic environment. The activity onset of those animals is continuously delayed, whereas the activity offset is stably coupled to "lights-on", leading to compression of activ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420520903398583
更新日期:2010-01-01 00:00:00
abstract::Our current 24-h society and the weekday-weekend switch of our social clocks may affect young children's sleep and circadian rhythms. However, such evidence is scarce. We conducted a nationwide epidemiological study of sleep and health in preschool children aged 3-5 years attending kindergarten or childcare centers in...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2016.1217231
更新日期:2016-01-01 00:00:00
abstract::Although several studies of glia have examined glial fibrillary acid protein (GFAP) and its relationship to the circadian rhythms of different organisms, they have not explored the daily GFAP oscillations in the putative pacemakers of the crayfish Procambarus clarkii or in other crustaceans. In this study we investiga...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1071385
更新日期:2015-01-01 00:00:00
abstract::The golden hamster (Mesocricetus auratus) is one of the most frequently used laboratory animals, particularly in chronobiological studies. One reason is its very robust and predictable rhythms, although the question arises whether this is an inbreeding effect or rather is typical for the species. We compared the daily...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100107968
更新日期:2001-11-01 00:00:00
abstract::The present research aimed to investigate in a model of teleost fish (rainbow trout) the existence of daily changes in activity and mRNA abundance of several proteins involved in major pathways of carbohydrate and lipid metabolism in liver, and to test whether or not both the light-dark cycle and food availability mig...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1100633
更新日期:2015-01-01 00:00:00
abstract::A circadian rhythm of heart rate and respiratory rate was seen at 1, 8, and 12 months of age in an infant born without ocular tissue, which supports the possibility that the time cues were nonphotic. No melatonin circadian rhythm was detected at any age up to 9 years of age, and this is most likely associated with the...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120037809
更新日期:2004-03-01 00:00:00
abstract::Coenzyme Q10 (CoQ10) or ubiquinone, a redox component of the mitochondrial electron transport chains, is a powerful antioxidant and membrane stabilizer that may prevent cellular damage during myocardial ischemia and reperfusion therapy. Coenzyme Q10 has been used primarily as an adjuvant therapy for some cardiomyopath...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120004544
更新日期:2002-05-01 00:00:00
abstract::In Drosophila circadian rhythms persist in constant darkness (DD). The small ventral Lateral Neurons (s-LNv) mainly control the behavioral circadian rhythm in consortium with the large ventral Lateral Neurons (l-LNv) and dorsal Lateral Neurons (LNd). It is believed that the molecular oscillations of clock genes are th...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1081/cbi-120038597
更新日期:2004-05-01 00:00:00
abstract::Total sleep deprivation (TSD) is known to impair sustained attention. However, previously reported effects of TSD on response inhibition are mixed. We administered a "stop-signal" variation of the psychomotor vigilance test, which included 25% of trials requiring withholding of a response to assess response inhibition...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1811718
更新日期:2020-08-25 00:00:00
abstract::Circadian rhythms are still expressed in animals that display daily torpor, implying a temperature compensation of the pacemaker. Nevertheless, it remains unclear how the clock works in hypothermic states and whether torpor itself, as a temperature pulse, affects the circadian system. To reveal changes in the clockwor...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520500522424
更新日期:2006-01-01 00:00:00
abstract::Daily variation in the absorption, metabolism and excretion of toxic substances will ultimately determine the actual concentration to which the cells and tissues are exposed. In aquaculture, Atlantic salmon (Salmo salar) can be frequently exposed to hydrogen peroxide (H2O2) to treat topical skin and gill infections, p...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1131164
更新日期:2016-01-01 00:00:00
abstract::Thermoregulatory processes have long been implicated in the initiation of human sleep. In this paper, we review our own studies conducted over the last decade showing a crucial role for melatonin as a mediator between the thermoregulatory and arousal system in humans. Distal heat loss, via increased skin temperature, ...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1080/07420520500545854
更新日期:2006-01-01 00:00:00
abstract::Nonrestorative sleep (NRS), characterized by a lack of refreshment upon awakening, has received little attention in the sleep literature even though it can occur and cause impairment apart from other sleep difficulties associated with insomnia. The Restorative Sleep Questionnaire (RSQ) is one of the first validated se...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2016.1212870
更新日期:2016-01-01 00:00:00
abstract::Humans may be subject to seasonal variations, as evidenced by the existence of seasonal affective disorder (SAD) and midwinter insomnia. However, some recent studies have shown that the seasonal variation in the phase of the circadian rhythm is relatively weak in healthy humans. In the present study, evidence is found...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529808993198
更新日期:1998-11-01 00:00:00
abstract::Biological processes are organized in time as innate rhythms defined by the period (τ), phase (peak [Φ] and trough time), amplitude (A, peak-trough difference) and mean level. The human time structure in its entirety is comprised of ultradian (τ < 20 h), circadian (20 h > τ < 28 h) and infradian (τ > 28 h) bioperiodic...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1080/07420528.2016.1184678
更新日期:2016-01-01 00:00:00
abstract::Semilunar and lunar rhythms are often controlled endogenously, but the mechanisms of their respective free-run periods, when external factors are absent, are mostly unclear. In this investigation, the authors studied the mechanism controlling the period of the circasemilunar emergence rhythm of a marine midge, Pontomy...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2012.728548
更新日期:2012-12-01 00:00:00
abstract::Circadian phase dependency in pharmacokinetics and hemodynamic effects on blood pressure and heart rate of different galenic formulations of nifedipine (immediate-release, sustained-release, and i.v. solution) were studied in healthy subjects or in hypertensive patients. Pharmacokinetics of immediate-release but not s...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529109059184
更新日期:1991-01-01 00:00:00
abstract::Most research papers published in Chronobiology International report the findings of investigations conducted on laboratory animals and human beings. The Journal, its editors and the publication committee endorse the compliance of investigators to the principles of the Declaration of Helsinki of the World Medical Asso...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120030045
更新日期:2004-01-01 00:00:00
abstract::The circadian rhythms of food and water consumption, the number of feeding and drinking episodes, oxygen consumption, carbon dioxide production, respiratory quotient, gross motor activity, and body temperature were measured in male B6C3F1 mice that were fed ad libitum (AL) or fed a caloric-restricted diet (CR). The CR...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420529009064635
更新日期:1990-01-01 00:00:00
abstract::Since 50-60% of the human body consists of water, the physiology of blood circulation might be affected by a full moon differently than during other days of the month. This study analyzed a potential association among lunar phases, seasonal variations, and the rate of spontaneous epistaxis. Consecutive admissions sole...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.916298
更新日期:2014-08-01 00:00:00
abstract::In Cushing's syndrome, the cortisol rhythm is impaired and can be associated with the disruption in the rhythmic expression of clock genes. In this study, we evaluated the expression of CLOCK, BMAL1, CRY1, CRY2, PER1, PER2, PER3 genes in peripheral blood leukocytes of healthy individuals (n = 13) and Cushing's disease...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1758126
更新日期:2020-06-01 00:00:00