Abstract:
:The effects of Chagas disease on the mammalian circadian system were studied in Trypanosoma cruzi-infected C57-B16J mice. Animals were inoculated with CAI or RA strains of T. cruzi or vehicle, parasitism confirmed by blood specimen visualization and locomotor activity rhythms analyzed by wheel-running recording. RA-strain infected mice exhibited significantly decreased amplitude of circadian rhythms, both under light-dark and constant dark conditions, probably due to motor deficiencies. CAI-treated animals showed normal locomotor activity rhythms. However, in these mice, reentrainment to a 6h phase shift of the LD cycle took significantly longer than controls, and application of 15min light pulses in DD produced smaller phase delays of the rhythms. All groups exhibited light-induced Fos expression in the suprachiasmatic nuclei. We conclude that the main effect of T. cruzi infection on the circadian system is an impairment of the motor output from the clock toward controlled rhythms, together with an effect on circadian visual sensitivity.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Fernández Alfonso T,Celentano AM,Gonzalez Cappa SM,Golombek DAdoi
10.1081/cbi-120017687subject
Has Abstractpub_date
2003-01-01 00:00:00pages
49-64issue
1eissn
0742-0528issn
1525-6073journal_volume
20pub_type
杂志文章abstract::The aim of the study was to evaluate the influence of chronotype (morning-type versus evening-type) living in a fixed sleep-wake schedule different from one's preferred sleep schedules on the time course of neurobehavioral performance during controlled extended wakefulness. The authors studied 9 morning-type and 9 eve...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.590623
更新日期:2011-07-01 00:00:00
abstract::Police officers are required to work irregular hours, which induces stress, fatigue, and sleep disruption, and they have higher rates of chronic disease and mortality. Cortisol is a well-known "stress hormone" produced via activation of the hypothalamic-pituitary-adrenal axis. An abnormal secretion pattern has been as...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.573112
更新日期:2011-05-01 00:00:00
abstract::The prevalence of delayed sleep phase syndrome (DSPS) has been estimated to be quite low. Although no genetic inheritance pattern has been described, it has been reported that close to 50% of DSPS patients have biological relatives with similar symptoms. A pedigree of one extended family with symptoms suggestive of DS...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100107518
更新日期:2001-09-01 00:00:00
abstract::The human sleep-wake cycle is characterized by significant individual differences. Those differences in the sleep-wake cycle are partially heritable but are also influenced by environmental factors like the light/dark cycle or social habits. In this study we analyse for the first time the sleep-wake rhythm of adolesce...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2012.741173
更新日期:2012-12-01 00:00:00
abstract::The evening chronotype is strongly associated with greater alcohol use, though mechanisms underlying this association are not well understood. The current study evaluated emotion regulation as a potential mechanism linking evening chronotype and alcohol use. Participants were 81 undergraduate students. Chronotype was ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1800028
更新日期:2020-12-01 00:00:00
abstract::Data on sleep or circadian abnormalities and metabolic disturbances in euthymic bipolar disorders are scarce and based on small sample sizes. The aim of this study was to explore the associations between sleep disturbances, chronotype and metabolic components in a large sample of euthymic patients with bipolar disorde...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2017.1332071
更新日期:2017-01-01 00:00:00
abstract::The aims of this study were to examine the genetic and environmental influences on diurnal preference and sleep quality, the association between these phenotypes, the genetic and environmental influences on this association, and the magnitude of overlap between these influences. Using a twin design, data on diurnal pr...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420521003663801
更新日期:2010-01-01 00:00:00
abstract::Loratadine is a second-generation histamine H(1)-receptor antagonist used in the treatment of allergic diseases. The aim of the study was to assess whether lethal toxicity and motor incoordination (neurotoxicity) of loratadine is circadian rhythm-dependent. A total of 210 male Swiss mice, aged 10 wk, were synchronized...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/CBI-200062369
更新日期:2005-01-01 00:00:00
abstract::The objective of the present study was to evaluate seasonal periodicity in the prevalence of Helicobacter pylori. A prospective study was performed on 1076 consecutive patients who were investigated in our hospital over a 3-year span because of epigastric complaints. Our findings indicate a significant accumulation of...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529909016947
更新日期:1999-11-01 00:00:00
abstract::Correlation between systolic (SBP) and diastolic (DBP) blood pressure (BP) level and target organ damage, cardiovascular disease (CVD) risk, and long-term prognosis is much greater for ambulatory BP monitoring (ABPM) than daytime office measurements. The 2013 ABPM guidelines specified herein are based on ABPM patient ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2013.750490
更新日期:2013-04-01 00:00:00
abstract::In the contemporary era, when life habits are largely determined by social needs and individual preferences, sleep is nevertheless affected by seasonal environmental changes. Japan has large seasonal and geographical alterations of photoperiod and climate. Japan does not adopt the daylight saving time (DST) system, ma...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1443118
更新日期:2018-07-01 00:00:00
abstract::Bone sarcomatous cells derived from human malignant tumors were cultured. The mitotic index was recorded for 39 hr. When the cultured cells originated from patients with cancer disease before any chemotherapy, ultradian mitotic rhythms of a 6-9-hr period were detected, but in many cases only after a sensitive statisti...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528909064628
更新日期:1989-01-01 00:00:00
abstract::Fatigue is an increasingly noted factor in road accidents. The ability to predict and be aware of impairment in terms of driving capability is important for potential legal liability and road safety. However, to date, there have been few studies that have investigated the accuracy of individuals in predicting how safe...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520601083391
更新日期:2006-01-01 00:00:00
abstract::ST8SIA2 and NCAM1 are functionally related genes forming polysialic acid (PSA) - neural cell adhesion molecule (NCAM) complex in suprachiasmatic nucleus (SCN), the regulating site of circadian biological rhythm. In this study, the relationship of ST8SIA2 and NCAM1 with circadian and seasonal rhythms of human behavior ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2017.1410827
更新日期:2018-03-01 00:00:00
abstract::Thermoregulatory processes have long been implicated in the initiation of human sleep. In this paper, we review our own studies conducted over the last decade showing a crucial role for melatonin as a mediator between the thermoregulatory and arousal system in humans. Distal heat loss, via increased skin temperature, ...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1080/07420520500545854
更新日期:2006-01-01 00:00:00
abstract::The last 20 yrs have seen a marked increase in studies utilizing actigraphy in free-living environments. The aim of the present study is to directly compare two commercially available actigraph devices with concurrent polysomnography (PSG) during a daytime nap in healthy young adults. Thirty healthy young adults, ages...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2013.782312
更新日期:2013-06-01 00:00:00
abstract::Daily schedules of many organisms, including birds, are thought to affect fitness. Timing in birds is based on circadian clocks that have a heritable period length, but fitness consequences for individuals in natural environments depend on the scheduling of entrained clocks. This chronotype, i.e., timing of an individ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2012.707159
更新日期:2012-10-01 00:00:00
abstract::Few studies have focused on the influence of circadian typology on drug use, and none has considered the use of illegal drugs and hazardous alcohol consumption. This study analyzes the influence of circadian typology on several types of drug consumption (habitual or sporadic), hangover symptoms (past 12 mos), and, mor...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.553018
更新日期:2011-04-01 00:00:00
abstract::Visual sensitivity rhythm has been assessed by several authors in animals. It shows an intrinsic circadian rhythm of some retinal mechanisms that could account for fluctuating sensitivity to light during the day in these species. However, very little is known concerning a possible circadian rhythm of visual sensitivit...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529709040540
更新日期:1997-01-01 00:00:00
abstract::The aim of this study was to determine the relationship between pilot workload, performance, subjective fatigue, sleep duration, number of sectors and flight duration during short-haul operations. Ninety pilots completed a NASA Task Load Index, Psychomotor Vigilance Task and a Samn-Perelli fatigue scale on top-of-desc...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1804924
更新日期:2020-08-24 00:00:00
abstract::Since 50-60% of the human body consists of water, the physiology of blood circulation might be affected by a full moon differently than during other days of the month. This study analyzed a potential association among lunar phases, seasonal variations, and the rate of spontaneous epistaxis. Consecutive admissions sole...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.916298
更新日期:2014-08-01 00:00:00
abstract::Twenty-two depressed subjects who met criteria for major depressive disorder were grouped according to their initial REM latency. Subjects with short (less than or equal to 60 min) initial REM latency were separated from those with normal (greater than 60 min) initial REM latency. Subjects with short initial REM laten...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529009056968
更新日期:1990-01-01 00:00:00
abstract::Treatment-related changes in neurobiological rhythms are of increasing interest to psychologists, psychiatrists, and biological rhythms researchers. New methods for analyzing change in rhythms are needed, as most common methods disregard the rich complexity of biological processes. Large time series data sets reflect ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520902772221
更新日期:2009-02-01 00:00:00
abstract::Changes in the free-running period of the circadian rhythms of hamsters occur after single nonphotic events such as a 3-h pulse of running induced by being put in a novel wheel. These changes are mostly in the direction of longer periods, and can exceed 0.2 h; the magnitude of the effect depends on the circadian phase...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529309059709
更新日期:1993-08-01 00:00:00
abstract::The objective of this study was to determine in a significant temporal pattern exists in the presentation of sickle cell vaso-occlusive pain crisis (SC-VPC) patients to an emergency department (ED) for treatment. This 28-month retrospective study of ED sickle cell crisis treatment involved 1128 presumably diurnally ac...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529609020915
更新日期:1996-12-01 00:00:00
abstract::Biological clock components have been detected in many epithelial tissues of the digestive tract of mammals (oral mucosa, pancreas, and liver), suggesting the existence of peripheral circadian clocks that may be entrainable by food. Our aim was to investigate the expression of main peripheral clock genes in colonocyte...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520500395011
更新日期:2005-01-01 00:00:00
abstract::It was previously shown that there is seasonality in the amount of dietary carbohydrate not absorbed from the intestine after breakfast, the amount of carbohydrate in winter being significantly larger than that in autumn in young Japanese subjects. In order to investigate this phenomenon further, the experiment was re...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520701531166
更新日期:2007-01-01 00:00:00
abstract::In previous research, it was determined that the altitude of origin altered the parameters of photic entrainment and free-running rhythmicity of adult locomotor activity of the high-altitude Himalayan (haH) strain (Hemkund-Sahib, 4121 m above sea level) of Drosophila helvetica compared to the low-altitude Himalayan (l...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520701649448
更新日期:2007-01-01 00:00:00
abstract::Intense artificial light can phase-shift circadian rhythms and improve performance, sleep, and well-being during shiftwork simulations. In real shiftworkers, however, exposure to sunlight and other time cues may decrease the efficacy of light treatment, and occupational and family responsibilities may make it impracti...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529509064509
更新日期:1995-04-01 00:00:00
abstract::The effect of stocking density on the locomotor activity of African catfish C. gariepinus under different light regimes was investigated. C. gariepinus were stocked under different densities (1, 5, or 10 fish/tank), and their locomotor activity recorded under light-dark (LD), constant light (LL), constant darkness (DD...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.606388
更新日期:2011-11-01 00:00:00