Abstract:
:Treatment-related changes in neurobiological rhythms are of increasing interest to psychologists, psychiatrists, and biological rhythms researchers. New methods for analyzing change in rhythms are needed, as most common methods disregard the rich complexity of biological processes. Large time series data sets reflect the intricacies of underlying neurobiological processes, but can be difficult to analyze. We propose the use of Fourier methods with multivariate permutation test (MPT) methods for analyzing change in rhythms from time series data. To validate the use of MPT for Fourier-transformed data, we performed Monte Carlo simulations and compared statistical power and family-wise error for MPT to Bonferroni-corrected and uncorrected methods. Results show that MPT provides greater statistical power than Bonferroni-corrected tests, while appropriately controlling family-wise error. We applied this method to human, pre- and post-treatment, serially-sampled neurotransmitter data to confirm the utility of this method using real data. Together, Fourier with MPT methods provides a statistically powerful approach for detecting change in biological rhythms from time series data.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Blackford JU,Salomon RM,Waller NGdoi
10.1080/07420520902772221subject
Has Abstractpub_date
2009-02-01 00:00:00pages
258-81issue
2eissn
0742-0528issn
1525-6073pii
908650712journal_volume
26pub_type
杂志文章abstract::Eight diurnally active (approximately 0730-1100 hr) adults (41-61 yr) suffering from nocturnal asthma volunteered for a double-blind, cross-over randomized study of a once-daily dosing (600-900 mg/24 hr) of Armophylline (Rorer s.a., France), a sustained-release theophylline given either at 0800 hr or 2000 hr for 8-day...
journal_title:Chronobiology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/07420528709083530
更新日期:1987-01-01 00:00:00
abstract::Predicting the future position of moving objects is an essential cognitive function used for many daily activities, such as driving, walking and reaching. The experiments described in this paper show a marked diurnal modulation of motion prediction in inflating image perception. This motion prediction was shown to be ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1053564
更新日期:2015-01-01 00:00:00
abstract::Previous research points to some inappropriate nutritional habits among nurses working night shifts. However, the knowledge of specific nutritional components of their diet has been limited. In the present study, we aimed to investigate the association between rotating night shifts of nurses and midwives and their usu...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1602051
更新日期:2019-07-01 00:00:00
abstract::Besides degrading vigilant attention, total sleep deprivation (TSD) impairs reversal learning performance and blunts affective reactions to feedback. Whether these effects are downstream consequences of information acquisition failures from degraded vigilant attention, or distinct from degraded vigilant attention, is ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1819306
更新日期:2020-09-22 00:00:00
abstract::Field observations spanning 1 year of the visits of two bee species--Tetraglossula bigamica (Hymenoptera: Colletidae) and Pseudagapostemon brasiliensis (Hymenoptera: Halictidae)--to the flowers of Ludwigia elegans (Onagraceae) evinced the existence of circadian and circannual components in the rhythms of activity both...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529309064478
更新日期:1993-02-01 00:00:00
abstract::Very little is known about the prevalence of morning work and its relationship with sleep and fatigue. The present study obtained data from a representative sample of the Swedish population (N = 5489) to address this limitation in the literature. The results show that 15% of the population commenced work, at least occ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2010.489001
更新日期:2010-07-01 00:00:00
abstract::Despite results linking shift work with ill health, only a few studies have addressed its relation with mortality. The purpose of the present study was to examine the hypothesis that shift work is a predictor of mortality. The study involved a sample of 22,411 individuals of the Swedish population. Data were obtained ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-200038520
更新日期:2004-01-01 00:00:00
abstract::The objective of the present study was to evaluate the sexual behavior of male rats kept under constant laboratory conditions for one entire year. A total of 213 sexually-inexperienced, male Wistar rats were maintained in controlled environmental conditions from birth. Depending the month in which they reached the age...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1715997
更新日期:2020-02-01 00:00:00
abstract::During a 7-10 day span, circadian rhythms of sleep-wake, self-rated fatigue and mood, oral temperature, eye-hand skill and right and left hand grip strength were investigated in eight subjects: five males (21-28 years of age), members of the French sabre fencing team selected for the 1984 Olympic Games in Los Angeles,...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528509055559
更新日期:1985-01-01 00:00:00
abstract::The 10 min psychomotor vigilance task (PVT) is commonly used in laboratory studies to assess the impact of sleep loss, sustained wakefulness, and/or time of day on neurobehavioral performance. In field settings, though, it may be impractical for participants to perform a test of this length. The aim of this study was ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520601067931
更新日期:2006-01-01 00:00:00
abstract::The prevalence of delayed sleep phase syndrome (DSPS) has been estimated to be quite low. Although no genetic inheritance pattern has been described, it has been reported that close to 50% of DSPS patients have biological relatives with similar symptoms. A pedigree of one extended family with symptoms suggestive of DS...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100107518
更新日期:2001-09-01 00:00:00
abstract::This study aimed to verify the prevalence and factors associated with excessive daytime sleepiness (EDS) among adolescents. In all, 1.132 people participated. They were aged between 14 and 19 years, of both sexes and they came from a city in southern Brazil. Many socio-demographic variables were collected (sex, age gr...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1633661
更新日期:2019-09-01 00:00:00
abstract::One of the supposed mechanisms that may lead to breast cancer (BC) is an alteration of circadian gene expression and DNA methylation. We undertook an integrated approach to identify methylation pattern of core circadian promoter regions in BC patients with regard to clinical features. We performed a quantitative methy...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1617732
更新日期:2019-08-01 00:00:00
abstract::In amphibians, voltage-gated sodium (Nav) channels in cone ON bipolar cells (ON-CBC) amplify cone signals in the dark and in mesopic background light. However, during light adaptation, dopamine, acting through D1 receptors (D1R), suppresses Nav channels and therefore act as a gain control mechanism. Curiously in roden...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.951054
更新日期:2015-02-01 00:00:00
abstract::In order to optimize chronotherapeutic schedules (designs), we examined the interindividual differences in chronopharmacologic effects of drugs with consideration of the following three factors: (a) inherited factors of direct relevance to chronopharmacology (genetic variability, gender-related differences) as well as...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420529309059721
更新日期:1993-12-01 00:00:00
abstract::Previously, we have demonstrated the postembryonic development of chicken (Gallus gallus domesticus L.) pineal gland functions expressed as changes in melatonin (MEL) biosynthesis. Pineal concentrations of MEL and its precursor serotonin (5-HT) were shown to increase between the 2nd and 16th day of life. We also found...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.955185
更新日期:2015-02-01 00:00:00
abstract::The appropriate time and place for sleep and waking are important factors for survival. Sleep and waking, rest and activity, flight and fight, feeding, and reproduction are all organized in relation to the day and night. A biological clock, the suprachiasmatic nucleus (SCN), synchronized by photic influences and other...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1080/07420520500545961
更新日期:2006-01-01 00:00:00
abstract::The aim of the present study was to test whether serum concentrations of leptin in ewes vary with a daily rhythm. For this purpose, we examined 24 h serum leptin profiles of ewes exposed to natural photoperiodic conditions and subjected to two different feeding schedules (regular feeding and fasting). The results show...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520500262989
更新日期:2005-01-01 00:00:00
abstract::The circadian melatonin rhythm is highly reproducible and generally not easily altered. The few perturbations that are capable of significantly changing either the amplitude or the pattern of the 24-h melatonin rhythm are summarized herein. Aging alters cyclic melatonin production by decreasing the amplitude of the no...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420529209064541
更新日期:1992-08-01 00:00:00
abstract::Phase-response experiments using 1-h light pulses (LPs) of 1,100 lux applied under constant dim light of 0.3 lux were conducted with common marmosets, Callithrix j. jacchus, in order to obtain a complete phase-response curve established according to the common experimental procedure in a diurnal primate. Maximal phase...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529409057243
更新日期:1994-10-01 00:00:00
abstract::Career decisions are based on the fit between an individual and his/her environment. This study explores the effect of person-environment fit regarding actual and preferred weekly working hours on early and late retirement intentions in a sample of 7,859 employees aged 50 to 65 years of age living in Germany. Findings...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1806291
更新日期:2020-08-24 00:00:00
abstract::In Drosophila circadian rhythms persist in constant darkness (DD). The small ventral Lateral Neurons (s-LNv) mainly control the behavioral circadian rhythm in consortium with the large ventral Lateral Neurons (l-LNv) and dorsal Lateral Neurons (LNd). It is believed that the molecular oscillations of clock genes are th...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1081/cbi-120038597
更新日期:2004-05-01 00:00:00
abstract::This article reviews the experimental and clinical data that form the basis for the chronotherapy of lung carcinoma, specifically, nonsmall cell lung cancer (NSCLC). Circadian rhythms in cell kinetics, immunological and endocrinological endpoints, and tumor markers are reviewed. Chronopharmacology and chronotolerance ...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1081/cbi-120002601
更新日期:2002-01-01 00:00:00
abstract::The circadian timing system adapts most of the mammalian physiology and behaviour to the 24 h light/dark cycle. This temporal coordination relies on endogenous circadian clocks present in virtually all tissues and organs and implicated in the regulation of key cellular processes including metabolism, transport and sec...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1046601
更新日期:2015-01-01 00:00:00
abstract::The electronic health record (EHR) contains rich histories of clinical care, but has not traditionally been mined for information related to sleep habits. Here, we performed a retrospective EHR study based on a cohort of 3,652 individuals with self-reported sleep behaviors documented from visits to the sleep clinic. T...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1508152
更新日期:2018-11-01 00:00:00
abstract::Ninety-five nonresident girls of a private school volunteered for the study with the teachers' help as well as parental consent. Ages were approximately 8, 9, and 10 years. They were synchronized with diurnal activity from 0730 to 2100 h and nocturnal rest. Fatigue, drowsiness, and attention were self-rated using visu...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529109059164
更新日期:1991-01-01 00:00:00
abstract::A physiological dose of orally administered melatonin shifts circadian rhythms in humans according to a phase-response curve (PRC) that is nearly opposite in phase with the PRCs for light exposure: melatonin delays circadian rhythms when administered in the morning and advances them when administered in the afternoon ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529209064550
更新日期:1992-10-01 00:00:00
abstract::Physiological and biomechanical constraints as well as their fluctuations throughout the day must be considered when studying determinant factors in the preferred pedaling rate of elite cyclists. The aim of this study was to monitor the diurnal variation of spontaneous pedaling rate and movement kinematics over the cr...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120024220
更新日期:2003-09-01 00:00:00
abstract::The effect of varying the dose-delivery time within a 24 h period (12:12 light-dark cycle) on the immunomodulatory properties of corn oil administered by gavage to 120 B6C3F1 female mice was investigated. Mice, housed in six separate boxes equipped with timers to regulate light onset and offset (staggered by 4 h incre...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529909019085
更新日期:1999-03-01 00:00:00
abstract::The suprachiasmatic nucleus (SCN) of the hypothalamus controls circadian rhythmicity in mammals (for reviews, see Refs. 33 and 59). Responses modulated by the SCN are numerous and include rhythms in sleep/wake cycles, locomotor, gnawing and general activity, temperature, ingestive behavior, and rhythms of hormonal and...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420529808998706
更新日期:1998-09-01 00:00:00