Interindividual differences in chronopharmacologic effects of drugs: a background for individualization of chronotherapy.

abstract：:Workers who meet the criteria for shift work disorder (SWD) have elevated levels of risk for various health and behavioral problems. However, the impact of having SWD on shiftworkers engaged in rapid-rotation schedules is unknown. Moreover, the risk factors for the occurrence of SWD remain unclear. To clarify these is...

journal_title：Chronobiology international

authors： Asaoka S,Aritake S,Komada Y,Ozaki A,Odagiri Y,Inoue S,Shimomitsu T,Inoue Y

更新日期：2013-05-01 00:00:00

abstract：:Chronic sympathetic denervation of the pineal gland by bilateral removal of the superior cervical ganglia (SCG) was performed on female rats 30 days before impregnation. The offspring, maintained in the dark from birth, had disruption of the malate dehydrogenase circadian rhythm in the testes at 25 days of age. A dail...

journal_title：Chronobiology international

authors： Vermouth NT,Carriazo CS,Gallará RV,Carpentieri AR,Bellavía SL

更新日期：1995-02-01 00:00:00

abstract：:Our current 24-h society and the weekday-weekend switch of our social clocks may affect young children's sleep and circadian rhythms. However, such evidence is scarce. We conducted a nationwide epidemiological study of sleep and health in preschool children aged 3-5 years attending kindergarten or childcare centers in...

journal_title：Chronobiology international

authors： Doi Y,Ishihara K,Uchiyama M

更新日期：2016-01-01 00:00:00

abstract：:Seasonal Affective Disorder (SAD) is a condition of regularly occurring depressions in winter with a remission the following spring or summer. In addition to depressed mood, the patients tend to experience increased appetite and an increased duration of sleep during the winter. SAD is a relatively common condition, af...

journal_title：Chronobiology international

authors： Magnusson A,Boivin D

更新日期：2003-03-01 00:00:00

abstract：:This retrospective study tested the hypothesis that disease control and treatment-related toxicity in patients undergoing high-dose radiotherapy (HDRT) for prostate cancer varies in a circadian manner. Patients with localized prostate adenocarcinoma receiving HDRT (median 78 Gy) to the prostate and involved seminal ve...

journal_title：Chronobiology international

authors： Hsu FM,Hou WH,Huang CY,Wang CC,Tsai CL,Tsai YC,Yu HJ,Pu YS,Cheng JC

更新日期：2016-01-01 00:00:00

abstract：:The length of the free-running period (τ) affects how an animal re-entrains after phase shifts of the light-dark (LD) cycle. Those with shorter periods adapt faster to phase advances than those with longer periods, whereas those with longer periods adapt faster to phase delays than those with shorter periods. The free...

journal_title：Chronobiology international

authors： Eastman CI,Molina TA,Dziepak ME,Smith MR

更新日期：2012-10-01 00:00:00

abstract：:The influence of environmental (extracellular) pH on the sporulation rhythm in Neurospora crassa was investigated for wild-type (frq+) and the mutants chr, frq1, frq7, and frq8. In all mutants, including wild type, the growth rate was found to be influenced strongly by extracellular pH in the range 4-9. On the other h...

journal_title：Chronobiology international

authors： Ruoff P,Behzadi A,Hauglid M,Vinsjevik M,Havås H

更新日期：2000-11-01 00:00:00

abstract：:The specific circadian role proposed for endogenous melatonin production was based on a study of sighted people who took low pharmacological doses (500 microg) of this chemical signal for the "biological night": the magnitude and direction of the induced phase shifts were dependent on what time of day exogenous melato...

journal_title：Chronobiology international

authors： Lewy AJ,Emens JS,Lefler BJ,Yuhas K,Jackman AR

更新日期：2005-01-01 00:00:00

abstract：:A double-blind randomized parallel-group trial was undertaken to evaluate the influence of the dosing time of sustained-release ketoprofen (SRK) on its acceptability and efficacy. The SRK was prescribed for 2 weeks (200 mg once a day) to 117 outpatients with osteoarthritis of the knee and/or hip. One group received SR...

journal_title：Chronobiology international

authors： Perpoint B,Mismetti P,Simitsidis S,Hocquart J,Rambaud C,Buchmuller A,Queneau P,Decousus H

更新日期：1994-04-01 00:00:00

abstract：:We ask if epidemiological studies into shift work and cancer may be prone to chronobiological errors. We illustrate how ignoring internal time (IT), or chronotype, may lead to what we call IT errors. Errors from truncating relevant external time (ET) information (activities start before and do not end with the shift) ...

journal_title：Chronobiology international

authors： Erren TC,Morfeld P

更新日期：2014-05-01 00:00:00

abstract：:Nonrestorative sleep (NRS), characterized by a lack of refreshment upon awakening, has received little attention in the sleep literature even though it can occur and cause impairment apart from other sleep difficulties associated with insomnia. The Restorative Sleep Questionnaire (RSQ) is one of the first validated se...

journal_title：Chronobiology international

authors： Tutek J,Emert SE,Dautovich ND,Lichstein KL

更新日期：2016-01-01 00:00:00

abstract：:In amphibians, voltage-gated sodium (Nav) channels in cone ON bipolar cells (ON-CBC) amplify cone signals in the dark and in mesopic background light. However, during light adaptation, dopamine, acting through D1 receptors (D1R), suppresses Nav channels and therefore act as a gain control mechanism. Curiously in roden...

journal_title：Chronobiology international

authors： Smith BJ,Côté PD,Tremblay F

更新日期：2015-02-01 00:00:00

abstract：:This study investigates if the serotoninergic system plays a role in chronotoxic effects of the anticancer agent oxaliplatin (l-OHP). Four groups of female rats (120 in total) synchronized with light-dark (12 h:12 h) were treated with: (i) saline, (ii) para-chlorophenylalanine (pCPA, an inhibitor of serotonin biosynth...

journal_title：Chronobiology international

authors： Boughattas NA,Ben Attia M,Ixart G,Lemaigre G,Mechkouri M,Reinberg A

更新日期：2002-11-01 00:00:00

abstract：:The prevalence of delayed sleep phase syndrome (DSPS) has been estimated to be quite low. Although no genetic inheritance pattern has been described, it has been reported that close to 50% of DSPS patients have biological relatives with similar symptoms. A pedigree of one extended family with symptoms suggestive of DS...

journal_title：Chronobiology international

authors： Ancoli-Israel S,Schnierow B,Kelsoe J,Fink R

更新日期：2001-09-01 00:00:00

abstract：:Various processes associated with mammalian reproduction exhibit circadian rhythms, yet no information is available concerning the presence of rhythmicity in meiosis-the crucial process of the production of sex cells. Following meiosis in cells derived from male mice exposed in vivo to daily light-dark cycles (LD), we...

journal_title：Chronobiology international

authors： Rienstein S,Dotan A,Avivi L,Ashkenazi I

更新日期：1998-01-01 00:00:00

abstract：:A variable number tandem repeat polymorphism (VNTR) in the period 3 (PER3) gene has been associated with heritable sleep and circadian variables, including self-rated chronotypes, polysomnographic (PSG) variables, insomnia and circadian sleep-wake disorders. This report describes novel molecular and clinical analyses ...

journal_title：Chronobiology international

authors： Mansour HA,Wood J,Chowdari KV,Tumuluru D,Bamne M,Monk TH,Hall MH,Buysse DJ,Nimgaonkar VL

更新日期：2017-01-01 00:00:00

abstract：:The effects of short-term food deprivation on the serum and renal distribution and nephrotoxicity of tobramycin were studied in female Sprague-Dawley rats maintained on a 14-h light/10-h dark cycle (light on: 06:00). For the distribution study, a single injection of tobramycin (40 mg/kg, i.p.) was administered at 14:0...

journal_title：Chronobiology international

authors： Lin L,Grenier L,LeBrun M,Bergeron MG,Thibault L,Labrecque G,Beauchamp D

更新日期：1996-07-01 00:00:00

abstract：:Although chronic alcohol intake is associated with widespread disruptions of sleep-wake cycles and other daily biological rhythms in both human alcoholics and experimental animals, the extent to which the chronobiological effects of alcohol are mediated by effects on the underlying circadian pacemaker remains unknown....

journal_title：Chronobiology international

authors： Rosenwasser AM,Logan RW,Fecteau ME

更新日期：2005-01-01 00:00:00

abstract：:Humans may be subject to seasonal variations, as evidenced by the existence of seasonal affective disorder (SAD) and midwinter insomnia. However, some recent studies have shown that the seasonal variation in the phase of the circadian rhythm is relatively weak in healthy humans. In the present study, evidence is found...

journal_title：Chronobiology international

authors： Van Dongen HP,Kerkhof GA,Souverijn JH

更新日期：1998-11-01 00:00:00

abstract：:Patients with resistant hypertension (RH) are at greater risk for stroke, renal insufficiency, and cardiovascular disease (CVD) events than are those for whom blood pressure (BP) is responsive to and well controlled by therapeutic interventions. Although all chronotherapy trials have compared the effects on BP regulat...

journal_title：Chronobiology international

authors： Hermida RC,Ríos MT,Crespo JJ,Moyá A,Domínguez-Sardiña M,Otero A,Sánchez JJ,Mojón A,Fernández JR,Ayala DE,Hygia Project Investigators.

更新日期：2013-03-01 00:00:00

abstract：:Fabry disease is a progressive disease characterized by an enzymatic deficiency of acid alpha-galactosidase and glycosphingolipids storage within the lysosomes. The disease has two phenotypes: classic and nonclassic. Excessive daytime sleepiness is a common sign reported by patients and can be caused by a circadian rh...

journal_title：Chronobiology international

authors： Vallim JRDS,Amaral FGD,Cipolla-Neto J,D'Almeida V

更新日期：2019-04-01 00:00:00

abstract：:Seasonal variations have been described in humans in several variables such as sleep, mood, appetite, food preferences, or body weight. We hypothesized that these variations could also influence the decrease in body weight rate in patients submitted to body weight loss interventions. Thus, here we tested the variation...

journal_title：Chronobiology international

authors： Cambras T,Pardina E,Carmona J,Ricart-Jane D,Minarro A,Ferrer R,Lecube A,Balibrea JM,Caubet E,González O,Vilallonga R,Cuello E,Fort JM,Baena-Fustegueras JA,Díez-Noguera A,Peinado-Onsurbe J

更新日期：2019-05-01 00:00:00

abstract：:Sleep-related problems, such as symptoms of insomnia, daytime sleepiness, shorter sleep duration, or a delayed sleep-wake schedule, are known to be risk factors for depression. In general, depression is more prevalent in women than in men, but sleep-related problems do not necessarily show similar gender predominance....

journal_title：Chronobiology international

authors： Morita Y,Sasai-Sakuma T,Asaoka S,Inoue Y

更新日期：2015-01-01 00:00:00

abstract：:A number of Djungarian hamsters (Phodopus sungorus) of our institute show activity patterns that seem incompatible with proper adjustment to a periodic environment. The activity onset of those animals is continuously delayed, whereas the activity offset is stably coupled to "lights-on", leading to compression of activ...

journal_title：Chronobiology international

authors： Schottner K,Weinert D

更新日期：2010-01-01 00:00:00

abstract：:The contribution of the renin-angiotensin-aldosterone system (RAAS) to the development of congestive heart failure (CHF) and hypertension (HT) has long been recognized. Medications that are commonly used in the course of CHF and HT are most often given with morning food for the sake of convenience and therapeutic comp...

journal_title：Chronobiology international

authors： Mochel JP,Fink M,Bon C,Peyrou M,Bieth B,Desevaux C,Deurinck M,Giraudel JM,Danhof M

更新日期：2014-06-01 00:00:00

abstract：:The circadian system is organized in a hierarchy of multiple oscillators, with the suprachiasmatic nucleus (SCN) as the master oscillator in mammals. The SCN is formed by a group of coupled cell oscillators. Knowledge of this coupling mechanism is essential to understanding entrainment and the expression of circadian ...

journal_title：Chronobiology international

authors： Silva CA,Melo LIM,Pires AR,Barbalho JC,Melo AV,Fernandes DAC,Oliveira EB,Azevedo CVM,Cambras T,Díez-Noguera A,Fontenele-Araujo J

更新日期：2018-01-01 00:00:00

abstract：:Appreciation of chronotherapy in hypertension continues to lag, despite clear demonstrations by many studies of (i) clinically relevant dosing-time differences of the beneficial and adverse effects of most blood pressure (BP) medications and (ii) significant association between reduced sleep-time BP decline of non-dip...

journal_title：Chronobiology international

authors： Portaluppi F,Smolensky MH

更新日期：2010-09-01 00:00:00

abstract：:Eveningness has been suggested as a facilitating factor in adaptation to shift work, with several studies reporting evening chronotypes (E-types) as better sleepers when on night shifts. Conversely, eveningness has been associated with more sleep complaints during day shifts. However, sleep during day shifts has recei...

journal_title：Chronobiology international

authors： Martin JS,Laberge L,Sasseville A,Bérubé M,Alain S,Houle J,Hébert M

更新日期：2015-06-01 00:00:00

abstract：:Predicting the future position of moving objects is an essential cognitive function used for many daily activities, such as driving, walking and reaching. The experiments described in this paper show a marked diurnal modulation of motion prediction in inflating image perception. This motion prediction was shown to be ...

journal_title：Chronobiology international

authors： Takao M,Miyajima H,Shinagawa T

更新日期：2015-01-01 00:00:00

abstract：:Sleep-wake regulation involves reciprocal interactions between sleep- and wake-promoting processes that inhibit one another. To uncover the signatures of the opponent processes underlying ultradian sleep cycles, principal component analysis was performed on the sets of 16 single-Hz log-transformed electroencephalograp...

journal_title：Chronobiology international

authors： Putilov AA

更新日期：2011-05-01 00:00:00