Dosing time optimizes sustained-release ketoprofen treatment of osteoarthritis.

abstract：:In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors. Blood pressure was measured by the oscillometric method using the blood pressure monitor 90202 from SpaceLabs, Inc. The measurements were taken from 06:00 to 22:00 h...

journal_title：Chronobiology international

authors： Osterziel KJ,Dietz R,Lemmer B

更新日期：1991-01-01 00:00:00

abstract：:Julien-Joseph Virey (1775-1846) held the position of pharmacist-in-chief at the Val-de-Grâce, a military hospital. He was an innovative pharmacist, naturalist, anthropologist, and philosopher and a prolific author. His writings encompassed a wide range of topics, although many of his ideas were sometimes harshly quest...

journal_title：Chronobiology international

authors： Reinberg AE,Lewy H,Smolensky M

更新日期：2001-03-01 00:00:00

abstract：:Circadian changes in activities and electrophoretic pattern of the intestinal brushborder enzymes alkaline phosphatase (EC 3.1.3.1), isomaltase (EC 3.2.1.10) and sucrase (EC 3.2.1.26) of normal rats and of rats with a lesion of the dorsomedial hypothalamus (DMH-rats) were studied. In contrast to the rhythm found in no...

journal_title：Chronobiology international

authors： Hekkens WT,van Rijn PA,Lukac-Bajalo J,Ungerer R,Rietveld WJ

更新日期：1985-01-01 00:00:00

abstract：:Mitochondrial experiments are of increasing interest in different fields of research. Inhibition of mitochondrian activities seems to play a role in Parkinson's disease and in this regard several animal models have used inhibitors of mitochondrial respiration such as rotenone or MPTP. Most of these experiments were do...

journal_title：Chronobiology international

authors： Simon N,Papa K,Vidal J,Boulamery A,Bruguerolle B

更新日期：2003-05-01 00:00:00

abstract：:Morningness-eveningness (chronotype) indicates the preferred time of intellectual and physical activity. This cross-sectional study had two main aims. The first aim was to explore associations among chronotype, quality of life, and relationship quality. The second aim of this study was to examine whether the similarit...

journal_title：Chronobiology international

authors： Tanyi Z,Mészáros V,Smohai M,Jakubovits E,Ferenczi A,Szili I,Kovács D,Kövi Z

更新日期：2020-12-01 00:00:00

abstract：:The rods in the retina are responsible for night vision, whereas the cone system enables day vision. We studied whether rod function in humans exhibits an endogenous circadian rhythm and if changes occur in conditions of prolonged darkness. Seven healthy subjects (mean age+/-SD: 25.6+/-12.3 yr) completed a 4.5-day pro...

journal_title：Chronobiology international

authors： Danilenko KV,Plisov IL,Wirz-Justice A,Hebert M

更新日期：2009-01-01 00:00:00

abstract：:In Drosophila circadian rhythms persist in constant darkness (DD). The small ventral Lateral Neurons (s-LNv) mainly control the behavioral circadian rhythm in consortium with the large ventral Lateral Neurons (l-LNv) and dorsal Lateral Neurons (LNd). It is believed that the molecular oscillations of clock genes are th...

journal_title：Chronobiology international

authors： Veleri S,Wülbeck C

更新日期：2004-05-01 00:00:00

abstract：:In amphibians, voltage-gated sodium (Nav) channels in cone ON bipolar cells (ON-CBC) amplify cone signals in the dark and in mesopic background light. However, during light adaptation, dopamine, acting through D1 receptors (D1R), suppresses Nav channels and therefore act as a gain control mechanism. Curiously in roden...

journal_title：Chronobiology international

authors： Smith BJ,Côté PD,Tremblay F

更新日期：2015-02-01 00:00:00

abstract：:Serotonergic neurotransmission and the master circadian CLOCK gene are physiological modulators of the circadian system. In addition, both are involved in the physiopathology of metabolic syndrome (MS). The authors sought to examine the potential effect of the gene-gene interaction between the functional 44-bp inserti...

journal_title：Chronobiology international

authors： Sookoian S,Gianotti TF,Burgueño A,Pirola CJ

更新日期：2010-07-01 00:00:00

abstract：:The ventromedial hypothalamic nucleus (VMH) regulates various autonomic, endocrine, and behavioral activities. These activities show annual changes, and the pineal gland is involved in their adjustment to environmental cues. Therefore, this study investigated whether the VMH belongs to the effector structures of the p...

journal_title：Chronobiology international

authors： Peschke D,Teichmann J,Peschke E

更新日期：2000-01-01 00:00:00

abstract：:Several substances change the period length of the circadian oscillator in the laminar pulvinus of Phaseolus coccineus L. if offered continuously via the transpiration stream to the isolated leaves in continuous light and constant temperature. The osmotica mannitol and PEG 6000 (polyethylene glycol) lengthen the circa...

journal_title：Chronobiology international

authors： Mayer WE,Maier M,Flach D

更新日期：1985-01-01 00:00:00

abstract：:Population multiple components is a statistical tool useful for the analysis of time-dependent hybrid data. With a small number of parameters, it is possible to model and to predict the periodic behavior of a population. In this article, we propose two methods to compare among populations rhythmometric parameters obta...

journal_title：Chronobiology international

authors： Fernández JR,Mojón A,Hermida RC

更新日期：2004-05-01 00:00:00

abstract：:We analyzed the association between change in work schedule and modifications in nutritional status. We performed a panel study with nursing professionals based on two surveys seven year apart (n = 372). Groups with no change in work schedule, change from daytime to night shift, and change from night to daytime shift ...

journal_title：Chronobiology international

authors： Siqueria K,Griep R,Rotenberg L,Silva-Costa A,Mendes da Fonseca Mde J

更新日期：2016-01-01 00:00:00

abstract：:Workers who meet the criteria for shift work disorder (SWD) have elevated levels of risk for various health and behavioral problems. However, the impact of having SWD on shiftworkers engaged in rapid-rotation schedules is unknown. Moreover, the risk factors for the occurrence of SWD remain unclear. To clarify these is...

journal_title：Chronobiology international

authors： Asaoka S,Aritake S,Komada Y,Ozaki A,Odagiri Y,Inoue S,Shimomitsu T,Inoue Y

更新日期：2013-05-01 00:00:00

abstract：:Chronotypes have been associated with psychopathology. The eveningness chronotype has been consistently linked with depressed states or depressive disorder, but the underlying mechanism remains unclear. Prior studies have shown associations between chronotype and personality traits that are linked to depression (e.g. ...

journal_title：Chronobiology international

authors： Antypa N,Verkuil B,Molendijk M,Schoevers R,Penninx BWJH,Van Der Does W

更新日期：2017-01-01 00:00:00

abstract：:Genetic analysis of Neurospora crassa has identified many mutants that affect the biological clock. In this article we review the cloning of two of these genes, frq and prd-4. Both genes were isolated using a chromosome walk technique. Subcloning experiments and subsequent Northern analysis of frq implicate the import...

journal_title：Chronobiology international

authors： Aronson BD,Johnson KA,Liu Q,Dunlap JC

更新日期：1992-06-01 00:00:00

abstract：:We ask if epidemiological studies into shift work and cancer may be prone to chronobiological errors. We illustrate how ignoring internal time (IT), or chronotype, may lead to what we call IT errors. Errors from truncating relevant external time (ET) information (activities start before and do not end with the shift) ...

journal_title：Chronobiology international

authors： Erren TC,Morfeld P

更新日期：2014-05-01 00:00:00

abstract：:A diary-based instrument-the Social Rhythm Metric (SRM)-was used to assess the level of stability of daily social and behavioral rhythms in a group of 239 healthy subjects (112 male, 127 female) ranging in age from 20 to 89 years. Each subject completed the instrument for two consecutive weeks, which were averaged to ...

journal_title：Chronobiology international

authors： Monk TH,Reynolds CF 3rd,Kupfer DJ,Hoch CC,Carrier J,Houck PR

更新日期：1997-05-01 00:00:00

abstract：:Fourteen ambulatory subjects, varying in their amount of habitual physical activity, were studied for 24 h during a total of 25 "typical" days. Rectal temperature was recorded every 6 minutes, an activity diary was filled in every half hour, and wrist activity and heart rate were monitored every minute. Actimetry and ...

journal_title：Chronobiology international

authors： Waterhouse J,Edwards B,Mugarza J,Flemming R,Minors D,Calbraith D,Williams G,Atkinson G,Reilly T

更新日期：1999-07-01 00:00:00

abstract：:COVID-19 and metabolic syndrome are devastating pandemics. Effective control of metabolic parameters and their dysfunction may help prevent or minimize the acute and devastating effects of SARS-CoV-2 by reducing the local inflammatory response and blocking the entry of the virus into cells. With such consideration in ...

journal_title：Chronobiology international

authors： Verd S,Beiro S,Fernandez-Bernabeu M,Ponce-Taylor J

更新日期：2020-06-01 00:00:00

abstract：:The contribution of the renin-angiotensin-aldosterone system (RAAS) to the development of congestive heart failure (CHF) and hypertension (HT) has long been recognized. Medications that are commonly used in the course of CHF and HT are most often given with morning food for the sake of convenience and therapeutic comp...

journal_title：Chronobiology international

authors： Mochel JP,Fink M,Bon C,Peyrou M,Bieth B,Desevaux C,Deurinck M,Giraudel JM,Danhof M

更新日期：2014-06-01 00:00:00

abstract：:Using structural equation modeling, it can be shown that long weekly working hours and work on weekends, nights, and in shifts have detrimental effects on psychovegetative health. Employees' reported subjective work-life balance also decreases with increasing number of hours worked/week, days worked on weekends, or at...

journal_title：Chronobiology international

authors： Wirtz A,Nachreiner F

更新日期：2010-07-01 00:00:00

abstract：:We evaluated their circadian rhythms using data from electrocardiographic records and examined the change in circadian period related to normal RR intervals for astronauts who completed a long-term (≥6-month) mission in space. The examinees were seven astronauts, five men and two women, from 2009 to 2010. Their mean ±...

journal_title：Chronobiology international

authors： Yamamoto N,Otsuka K,Kubo Y,Hayashi M,Mizuno K,Ohshima H,Mukai C

更新日期：2015-04-01 00:00:00

abstract：:Diurnal variation in muscle performance has been well documented in the past few years, but almost exclusively in the male population. The possible effects of the menstrual cycle on human circadian rhythms have remained equivocal, particularly in the context of muscle strength. The purpose of the study was to analyze ...

journal_title：Chronobiology international

authors： Bambaeichi E,Reilly T,Cable NT,Giacomoni M

更新日期：2004-07-01 00:00:00

abstract：:Career decisions are based on the fit between an individual and his/her environment. This study explores the effect of person-environment fit regarding actual and preferred weekly working hours on early and late retirement intentions in a sample of 7,859 employees aged 50 to 65 years of age living in Germany. Findings...

journal_title：Chronobiology international

authors： Wöhrmann AM,Brauner C,Michel A

更新日期：2020-08-24 00:00:00

abstract：:Light-at-night (LAN) is a worldwide problem co-distributed with breast cancer prevalence. We hypothesized that exposure to LAN is coincided with a decreased melatonin (MLT) secretion level, followed by epigenetic modifications and resulted in higher breast cancer tumors growth-rate. Accordingly, we studied the effect ...

journal_title：Chronobiology international

authors： Schwimmer H,Metzer A,Pilosof Y,Szyf M,Machnes ZM,Fares F,Harel O,Haim A

更新日期：2014-02-01 00:00:00

abstract：:A preliminary study was conducted to evaluate the change in nocturnal concentrations of testosterone, luteinizing hormone, growth hormone, prolactin, thyroxine, and cortisol following a control day (no exercise) and on a day in which exercise was performed. Exercise consisted of 90 min of cycling at 70% of each subjec...

journal_title：Chronobiology international

authors： Hackney AC,Ness RJ,Schrieber A

更新日期：1989-01-01 00:00:00

abstract：:Earlier we reported that in a number of experiments pineal melatonin production in rats under constant laboratory conditions displayed seasonal rhythms but subsequently were not always able to confirm this. Since there was no indication under which conditions such rhythms may be present, we performed four consecutive ...

journal_title：Chronobiology international

authors： Bartsch H,Mecke D,Probst H,Küpper H,Seebald E,Salewski L,Stehle T,Bartsch C

更新日期：2012-10-01 00:00:00

abstract：:Chronic sympathetic denervation of the pineal gland by bilateral removal of the superior cervical ganglia (SCG) was performed on female rats 30 days before impregnation. The offspring, maintained in the dark from birth, had disruption of the malate dehydrogenase circadian rhythm in the testes at 25 days of age. A dail...

journal_title：Chronobiology international

authors： Vermouth NT,Carriazo CS,Gallará RV,Carpentieri AR,Bellavía SL

更新日期：1995-02-01 00:00:00

abstract：:Long working hours have been associated with an increased risk of cardiovascular disease, but its relationship with hypertension remains unclear. The objective of this study is to examine the relationship between overtime and presence of hypertension using data from a large-scale multi-company study in Japan. Particip...

journal_title：Chronobiology international

authors： Imai T,Kuwahara K,Nishihara A,Nakagawa T,Yamamoto S,Honda T,Miyamoto T,Kochi T,Eguchi M,Uehara A,Kuroda R,Omoto D,Nagata T,Pham NM,Kurotani K,Nanri A,Akter S,Kabe I,Mizoue T,Sone T,Dohi S,Japan Epidemiology Coll

更新日期：2014-12-01 00:00:00