Abstract:
:The circadian melatonin rhythm is highly reproducible and generally not easily altered. The few perturbations that are capable of significantly changing either the amplitude or the pattern of the 24-h melatonin rhythm are summarized herein. Aging alters cyclic melatonin production by decreasing the amplitude of the nocturnal melatonin peak in all species in which it has been studied. The best known acute suppressor of nocturnal melatonin is light exposure. The brightness of light required to acutely depress pineal melatonin production is species dependent; of the visible wavelengths, those in the blue range (approximately 500-520 nm) seem most effective in suppressing melatonin production. Nonvisible, nonionizing radiation in the extremely low frequency range (e.g., 60 Hz) seems also capable of altering pineal melatonin synthesis. Hormones have relatively little influence on the circadian production of melatonin, although either adrenalectomy or hypophysectomy does attenuate the amplitude of the melatonin cycle. Exercise at the time of high melatonin production rapidly depresses pineal concentrations of the indole without influencing its synthesis; the mechanism of this suppression remains unknown.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Reiter RJ,Richardson BAdoi
10.3109/07420529209064541subject
Has Abstractpub_date
1992-08-01 00:00:00pages
314-21issue
4eissn
0742-0528issn
1525-6073journal_volume
9pub_type
杂志文章,评审abstract::We aimed to study the association of perceived control over scheduling of shifts with objectively measured working hour characteristics in shift workers. The participants were 5128 hospital employees (91% women, 85% nursing personnel, average age 43 years) in period-based work (114:45h/3 weeks) from the 2015 Finnish P...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1520240
更新日期:2019-01-01 00:00:00
abstract::Circadian rhythms are still expressed in animals that display daily torpor, implying a temperature compensation of the pacemaker. Nevertheless, it remains unclear how the clock works in hypothermic states and whether torpor itself, as a temperature pulse, affects the circadian system. To reveal changes in the clockwor...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520500522424
更新日期:2006-01-01 00:00:00
abstract::Previous studies have reported sex differences in the pathophysiology of hypertension and responses to blood pressure (BP)-lowering medications. Moreover, men exhibit typically higher BP than women, the differences being greater for systolic (SBP) than diastolic (DBP) BP. These differences become apparent during adole...
journal_title:Chronobiology international
pub_type: 杂志文章,随机对照试验
doi:10.3109/07420528.2012.701487
更新日期:2013-03-01 00:00:00
abstract::Humans may be subject to seasonal variations, as evidenced by the existence of seasonal affective disorder (SAD) and midwinter insomnia. However, some recent studies have shown that the seasonal variation in the phase of the circadian rhythm is relatively weak in healthy humans. In the present study, evidence is found...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529808993198
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:Morning stiffness and plasma cytokine levels in rheumatoid arthritis (RA) patients exhibit 24-hour variations. Tumor necrosis factor-α (TNF-α) plays a central role in RA clinical conditions, including the invasion of inflammatory cells, destruction of cartilage, systemic inflammatory response and its levels s...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2013.878350
更新日期:2014-05-01 00:00:00
abstract::Data on sleep or circadian abnormalities and metabolic disturbances in euthymic bipolar disorders are scarce and based on small sample sizes. The aim of this study was to explore the associations between sleep disturbances, chronotype and metabolic components in a large sample of euthymic patients with bipolar disorde...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2017.1332071
更新日期:2017-01-01 00:00:00
abstract::Acute thrombotic events frequently occur in the early morning among hyperlipidemic patients. The activity of plasminogen activator inhibitor-1 (PAI-1), a potent inhibitor of the fibrinolytic system, oscillates daily, and this is considered one mechanism that underlies the morning onset of acute thrombotic events in hy...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2010.515324
更新日期:2010-10-01 00:00:00
abstract::Ceftazidime, a third-generation cephalosporin, is widely used for the treatment of Pseudomonas aeruginosa infections. The aims of the present study were to characterize the pharmacokinetics of ceftazidime and to estimate the T > MIC against P. aeruginosa, after its intramuscular (i.m.) administration at two different ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420521003664239
更新日期:2010-05-01 00:00:00
abstract::The 3111T/C single nucleotide polymorphism (SNP) of Circadian Locomotor Output Cycles Kaput (CLOCK) gene reportedly affects gastric motility before breakfast. It is of interest to know whether this SNP can affect the motility during the daytime. We investigated the association between the CLOCK 3111T/C SNP and several...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2017.1373660
更新日期:2017-01-01 00:00:00
abstract::In Channa punctatus, a significant daily variation in hypothalamic 5-HT level and monoamine oxidase (MAO) activity was noticed in preparatory phase (February), but not in prespawning (May) or postspawning (November) phases. Hypothalamic dopamine (DA) and noradrenaline (NA), on the other hand, showed marked daily varia...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528809067776
更新日期:1988-01-01 00:00:00
abstract::Previous studies have demonstrated seasonal variation in the incidence of acute myocardial infarction (AMI) with an increase in cases during the winter months. However, they did not assess whether ST-elevation MI (STEMI) and non-ST-elevation MI (NSTEMI) exhibit similar changes. The object of this study was to compare ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520701800611
更新日期:2007-01-01 00:00:00
abstract::We analyzed the effect of natural solar insolation and artificial photoperiodic conditions on melatonin MT1 receptor expression of a tropical rodent, Funambulus pennanti. Melatonin mediates reproductive and circadian responses and regulates the production of a large number of cytokines, including interleukin-2 (IL-2),...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420520903540960
更新日期:2009-12-01 00:00:00
abstract::Phase-response experiments using 1-h light pulses (LPs) of 1,100 lux applied under constant dim light of 0.3 lux were conducted with common marmosets, Callithrix j. jacchus, in order to obtain a complete phase-response curve established according to the common experimental procedure in a diurnal primate. Maximal phase...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529409057243
更新日期:1994-10-01 00:00:00
abstract::Sleep-wake regulation involves reciprocal interactions between sleep- and wake-promoting processes that inhibit one another. To uncover the signatures of the opponent processes underlying ultradian sleep cycles, principal component analysis was performed on the sets of 16 single-Hz log-transformed electroencephalograp...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.565136
更新日期:2011-05-01 00:00:00
abstract::In the current study, we studied behavioral patterns, such as foraging, activity, standing, and laying in a population of cattle wandering on streets of Raipur city. We also determined the effects of four environmental factors (temperature, humidity, light, and noise intensities) on these behaviors. We recorded all fo...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1644345
更新日期:2019-10-01 00:00:00
abstract::The first aim of the study was to assess clock-time patterning of work-related injuries (WRIs) of firemen (FM) of Saône et Loire-71 (France) during the 4-yr span of 1 January 2004 to 31 December 2007. FM of this service are legally required to log every WRI and seek its evaluation by the medical service, whether the W...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.603170
更新日期:2011-10-01 00:00:00
abstract::The contribution of the renin-angiotensin-aldosterone system (RAAS) to the development of congestive heart failure (CHF) and hypertension (HT) has long been recognized. Medications that are commonly used in the course of CHF and HT are most often given with morning food for the sake of convenience and therapeutic comp...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.897711
更新日期:2014-06-01 00:00:00
abstract::Dysregulation of the system of nitric oxide (NO)-cyclic 3',5'-guanosine monophosphate (cGMP) might be involved in the development of hypertension in transgenic hypertensive TGR(mREN2)27 (TGR) rats. The present study was performed to determine possible differences in the day-night pattern and the urinary excretion rate...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529909116860
更新日期:1999-05-01 00:00:00
abstract::Hyperphosphatemia is a common complication of chronic kidney disease (CKD) and is associated with cardiovascular disease (CVD), which has contributed to an increase in mortality of CKD patients. The onset of CVD often varies by time-of-day. Acute myocardial infarction or ventricular arrhythmia occurs most frequently d...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1486850
更新日期:2018-09-01 00:00:00
abstract::The prevalence of delayed sleep phase syndrome (DSPS) has been estimated to be quite low. Although no genetic inheritance pattern has been described, it has been reported that close to 50% of DSPS patients have biological relatives with similar symptoms. A pedigree of one extended family with symptoms suggestive of DS...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100107518
更新日期:2001-09-01 00:00:00
abstract::In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors. Blood pressure was measured by the oscillometric method using the blood pressure monitor 90202 from SpaceLabs, Inc. The measurements were taken from 06:00 to 22:00 h...
journal_title:Chronobiology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/07420529109059177
更新日期:1991-01-01 00:00:00
abstract::A number of Djungarian hamsters (Phodopus sungorus) of our institute show activity patterns that seem incompatible with proper adjustment to a periodic environment. The activity onset of those animals is continuously delayed, whereas the activity offset is stably coupled to "lights-on", leading to compression of activ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420520903398583
更新日期:2010-01-01 00:00:00
abstract::Shift workers are known to have an increased risk of developing cardiovascular disease (CVD) compared with day workers. An important factor contributing to this increased risk could be the increased incidence of postprandial metabolic risk factors for CVD among shift workers, as a consequence of the maladaptation of e...
journal_title:Chronobiology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1081/cbi-200037171
更新日期:2004-01-01 00:00:00
abstract::General anesthesia combined with surgery is commonly associated with post-operative stress-response in humans. Effects on the hypothalamic-pituitary-adrenal axis (HPA) during and after anesthesia are correlated with the magnitude of surgery and choice of anesthetics. The aim of our study in rats was to characterize th...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520902926033
更新日期:2009-05-01 00:00:00
abstract::Diurnal and seasonal rhythms of cortisol, testosterone, and DHEA were examined, as little is known about the relationship between these rhythmicities and pubertal development. Salivary samples were obtained from 60 boys and 60 girls at approximately 07:45, 08:00, 08:30, 12:00, 16:50, and 21:00 h. The participants' age...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520701649471
更新日期:2007-01-01 00:00:00
abstract::It has been previously documented that aspirin induced gastric injury of healthy male volunteers was greater in the morning than in the evening. We have also reported that fasting gastric acid secretion rates and gastric retention times for solids were lower in the morning hours of the circadian cycle. We hypothesized...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528809067784
更新日期:1988-01-01 00:00:00
abstract::Multiple components of the circadian central clock are phosphoproteins, and it has become increasingly clear that posttranslational modification is an important regulator of circadian rhythm in diverse organisms, from dinoflagellates to humans. Genetic studies in Drosophila have identified double-time (dbt), a serine/...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1081/cbi-100103963
更新日期:2001-05-01 00:00:00
abstract::The effect of altitude on four basic properties of the pacemaker controlling the circadian rhythm of oviposition in two strains of Drosophila ananassae was determined. The high altitude (HA) strain from Badrinath (5123 m above sea level) had a low amplitude peak in the forenoon while the low altitude (LA) strain from ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-200030508
更新日期:2005-01-01 00:00:00
abstract::The evening chronotype is strongly associated with greater alcohol use, though mechanisms underlying this association are not well understood. The current study evaluated emotion regulation as a potential mechanism linking evening chronotype and alcohol use. Participants were 81 undergraduate students. Chronotype was ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1800028
更新日期:2020-12-01 00:00:00
abstract::Few studies have focused on the influence of circadian typology on drug use, and none has considered the use of illegal drugs and hazardous alcohol consumption. This study analyzes the influence of circadian typology on several types of drug consumption (habitual or sporadic), hangover symptoms (past 12 mos), and, mor...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.553018
更新日期:2011-04-01 00:00:00