The CLOCK 3111T/C single nucleotide polymorphism and daytime fluctuations of gastric motility in healthy young women: A preliminary study.

Abstract:

:The 3111T/C single nucleotide polymorphism (SNP) of Circadian Locomotor Output Cycles Kaput (CLOCK) gene reportedly affects gastric motility before breakfast. It is of interest to know whether this SNP can affect the motility during the daytime. We investigated the association between the CLOCK 3111T/C SNP and several gastric motility parameters during the time period from 8:00 to 20:00 in 34 young women with scheduled meals. There were similar daytime fluctuations in gastric motility before and after the meals between the major (T/T) and minor (T/C) allele carriers. The CLOCK SNP may affect daytime gastric motility less than food stimulation.

journal_name

Chronobiol Int

authors

Yamaguchi M,Kotani K,Tsuzaki K,Motokubota N,Komai N,Sakane N,Moritani T,Nagai N

doi

10.1080/07420528.2017.1373660

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

1478-1482

issue

10

eissn

0742-0528

issn

1525-6073

journal_volume

34

pub_type

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