Output signals of the SCN.

abstract：:The pharmacokinetics of naproxen was studied in 12 healthy male volunteers after a single oral dose of 500 mg at 10:00 and 22:00 h. Ingestion of drug at 22:00 h delayed the occurrence of peak serum levels (p < 0.0212). None of the other pharmacokinetic parameters exhibited any significant diurnal variations. ...

journal_title：Chronobiology international

authors： Rao BR,Rambhau D,Rao VV

更新日期：1993-04-01 00:00:00

abstract：:In the free-running circadian locomotor activity rhythm of a 7-year-old male owl monkey (Aotus lemurinus griseimembra) kept under constant light and climatic conditions (LL 0.2 lux, 25 degrees C +/- 1 degrees C, 60 +/- 5% relative humidity [RH]), a second rhythm component developed that showed strong relative coordina...

journal_title：Chronobiology international

authors： Erkert HG

更新日期：2000-03-01 00:00:00

abstract：:The present article analyzes locomotor activity rhythms in Tinca tinca. To that end, three different experiments were conducted on 24 animals (20 g body weight) kept in pairs in 60-liter aquaria fitted with infrared sensors connected to a computer to continuously record fish movements. The first experiment was designe...

journal_title：Chronobiology international

authors： Herrero MJ,Madrid JA,Sánchez-Vázquez FJ

更新日期：2003-11-01 00:00:00

abstract：:Sleep and fatigue-associated symptoms are prominent during chemotherapy. The purpose of this pilot study was to examine bright light effects on sleep disruption, fatigue, daytime sleepiness, depression, and quality of life (QOL) in women with stage I-III breast cancer undergoing chemotherapy. In this 2-group randomize...

journal_title：Chronobiology international

authors： Wu HS,Davis JE,Chen L

更新日期：2021-01-21 00:00:00

abstract：:A physiological dose of orally administered melatonin shifts circadian rhythms in humans according to a phase-response curve (PRC) that is nearly opposite in phase with the PRCs for light exposure: melatonin delays circadian rhythms when administered in the morning and advances them when administered in the afternoon ...

journal_title：Chronobiology international

authors： Lewy AJ,Ahmed S,Jackson JM,Sack RL

更新日期：1992-10-01 00:00:00

abstract：:In order to optimize chronotherapeutic schedules (designs), we examined the interindividual differences in chronopharmacologic effects of drugs with consideration of the following three factors: (a) inherited factors of direct relevance to chronopharmacology (genetic variability, gender-related differences) as well as...

journal_title：Chronobiology international

authors： Reinberg AE,Ashkenazi IE

更新日期：1993-12-01 00:00:00

abstract：:Circadian rhythms in plants are liable to masking, i.e. alterations by environmental influencing agents. Experiments have been reported for both positive and negative masking, attributed to a Zeitgeber which may either increase or decrease the amplitude of a circadian rhythm (CR). In some instances, the CR may even be...

journal_title：Chronobiology international

authors： Vanden Driessche T,Guisset JL,Gaspar T,Kevers C,Koukkari WL

更新日期：1989-01-01 00:00:00

abstract：:This study investigates if the serotoninergic system plays a role in chronotoxic effects of the anticancer agent oxaliplatin (l-OHP). Four groups of female rats (120 in total) synchronized with light-dark (12 h:12 h) were treated with: (i) saline, (ii) para-chlorophenylalanine (pCPA, an inhibitor of serotonin biosynth...

journal_title：Chronobiology international

authors： Boughattas NA,Ben Attia M,Ixart G,Lemaigre G,Mechkouri M,Reinberg A

更新日期：2002-11-01 00:00:00

abstract：:Multiple components of the circadian central clock are phosphoproteins, and it has become increasingly clear that posttranslational modification is an important regulator of circadian rhythm in diverse organisms, from dinoflagellates to humans. Genetic studies in Drosophila have identified double-time (dbt), a serine/...

journal_title：Chronobiology international

authors： Eide EJ,Virshup DM

更新日期：2001-05-01 00:00:00

abstract：:Depression is a multifactorial illness that is highly prevalent among medical students (MS). Chronotypes, which reflect circadian preference in humans, as well as academic stress have been associated with depression in different populations. However, it is not known how chronotype and stress might alone or in combinat...

journal_title：Chronobiology international

authors： Romo-Nava F,Tafoya SA,Gutiérrez-Soriano J,Osorio Y,Carriedo P,Ocampo B,Bobadilla RI,Heinze G

更新日期：2016-01-01 00:00:00

abstract：:The season of birth has been suggested to influence the development of some diseases, but its role in lung fibrosis seems to not have been studied previously. The aim of this study was to investigate the relation between the season of birth and fibrotic abnormalities as detected radiologically in high-resolution compu...

journal_title：Chronobiology international

authors： Hannu T,Jaakkola MS,Kivisaari L,Huuskonen MS,Vehmas T

更新日期：2007-01-01 00:00:00

abstract：:The effects of short-term food deprivation on the serum and renal distribution and nephrotoxicity of tobramycin were studied in female Sprague-Dawley rats maintained on a 14-h light/10-h dark cycle (light on: 06:00). For the distribution study, a single injection of tobramycin (40 mg/kg, i.p.) was administered at 14:0...

journal_title：Chronobiology international

authors： Lin L,Grenier L,LeBrun M,Bergeron MG,Thibault L,Labrecque G,Beauchamp D

更新日期：1996-07-01 00:00:00

abstract：:Ninety-five nonresident girls of a private school volunteered for the study with the teachers' help as well as parental consent. Ages were approximately 8, 9, and 10 years. They were synchronized with diurnal activity from 0730 to 2100 h and nocturnal rest. Fatigue, drowsiness, and attention were self-rated using visu...

journal_title：Chronobiology international

authors： Guérin N,Boulenguiez S,Reinberg A,Di Costanzo G,Guran P,Touitou Y

更新日期：1991-01-01 00:00:00

abstract：:The aims of this study were to examine the genetic and environmental influences on diurnal preference and sleep quality, the association between these phenotypes, the genetic and environmental influences on this association, and the magnitude of overlap between these influences. Using a twin design, data on diurnal pr...

journal_title：Chronobiology international

authors： Barclay NL,Eley TC,Buysse DJ,Archer SN,Gregory AM

更新日期：2010-01-01 00:00:00

abstract：:Facebook has become the most popular social networking site round the world. In seeking an explanation for this phenomenon, individual differences in circadian functioning seem to be an interesting issue. The main aim of this study was to examine the potential associations between morningness/eveningness and Facebook ...

journal_title：Chronobiology international

authors： Blachnio A,Przepiorka A,Díaz-Morales JF

更新日期：2015-01-01 00:00:00

abstract：:Appreciation of chronotherapy in hypertension continues to lag, despite clear demonstrations by many studies of (i) clinically relevant dosing-time differences of the beneficial and adverse effects of most blood pressure (BP) medications and (ii) significant association between reduced sleep-time BP decline of non-dip...

journal_title：Chronobiology international

authors： Portaluppi F,Smolensky MH

更新日期：2010-09-01 00:00:00

abstract：:Earlier we reported that in a number of experiments pineal melatonin production in rats under constant laboratory conditions displayed seasonal rhythms but subsequently were not always able to confirm this. Since there was no indication under which conditions such rhythms may be present, we performed four consecutive ...

journal_title：Chronobiology international

authors： Bartsch H,Mecke D,Probst H,Küpper H,Seebald E,Salewski L,Stehle T,Bartsch C

更新日期：2012-10-01 00:00:00

abstract：:Correlation between systolic (SBP) and diastolic (DBP) blood pressure (BP) level and target organ damage, cardiovascular disease (CVD) risk, and long-term prognosis is much greater for ambulatory BP monitoring (ABPM) than daytime office measurements. The 2013 ABPM guidelines specified herein are based on ABPM patient ...

journal_title：Chronobiology international

authors： International Society for Chronobiology.,American Association of Medical Chronobiology and Chronotherapeutics.,Spanish Society of Applied Chronobiology, Chronotherapy, and Vascular Risk.,Spanish Society of Atherosclerosis.,Romanian Society of In

更新日期：2013-04-01 00:00:00

abstract：:The intrinsic circadian clock requires photoentrainment to synchronize the 24-hour solar day. Therefore, light stimulation is an important component of chronobiological research. Currently, the chronobiological research field overwhelmingly uses photopic illuminance that is based on the luminous efficiency function, V...

journal_title：Chronobiology international

authors： Cao D,Barrionuevo PA

更新日期：2015-03-01 00:00:00

abstract：:The objectives of the study were to investigate the associations between night work and disability pension (DP) due to all causes, cardiovascular (CVD), mental, and other diagnoses, adjusting for familial confounding. The material of the study included comprehensive survey data on 27 165 Swedish twins born in 1935-195...

journal_title：Chronobiology international

authors： Ropponen A,Narusyte J,Mather L,Mittendorfer-Rutz E,Åkerstedt T,Svedberg P

更新日期：2018-02-01 00:00:00

abstract：:The length of the free-running period (τ) affects how an animal re-entrains after phase shifts of the light-dark (LD) cycle. Those with shorter periods adapt faster to phase advances than those with longer periods, whereas those with longer periods adapt faster to phase delays than those with shorter periods. The free...

journal_title：Chronobiology international

authors： Eastman CI,Molina TA,Dziepak ME,Smith MR

更新日期：2012-10-01 00:00:00

abstract：:ST8SIA2 and NCAM1 are functionally related genes forming polysialic acid (PSA) - neural cell adhesion molecule (NCAM) complex in suprachiasmatic nucleus (SCN), the regulating site of circadian biological rhythm. In this study, the relationship of ST8SIA2 and NCAM1 with circadian and seasonal rhythms of human behavior ...

journal_title：Chronobiology international

authors： Yang SY,Baek JH,Cho Y,Cho EY,Choi Y,Kim Y,Park T,Hong KS

更新日期：2018-03-01 00:00:00

abstract：:It has frequently been reported that exposure to artificial light at night (ALAN) may cause negative health effects, such as breast cancer, circadian phase disruption and sleep disorders. Here, we reviewed the literature assessing the effects of human exposure to ALAN in order to list the health effects of various asp...

journal_title：Chronobiology international

authors： Cho Y,Ryu SH,Lee BR,Kim KH,Lee E,Choi J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Patients with mood disorders show a high dependence of behavior on the molecular characteristics of the biological clock. CLOCK rs1801260 gene polymorphism influences circadian behavior in bipolar disorder (BD), with *C carriers showing a delayed sleep onset and worse insomnia. Sleep phase delay and insomnia...

journal_title：Chronobiology international

authors： Benedetti F,Riccaboni R,Dallaspezia S,Locatelli C,Smeraldi E,Colombo C

更新日期：2015-01-01 00:00:00

abstract：:The appropriate time and place for sleep and waking are important factors for survival. Sleep and waking, rest and activity, flight and fight, feeding, and reproduction are all organized in relation to the day and night. A biological clock, the suprachiasmatic nucleus (SCN), synchronized by photic influences and other...

journal_title：Chronobiology international

authors： Selbach O,Haas HL

更新日期：2006-01-01 00:00:00

abstract：:Many immune parameters exhibit daily and circadian oscillations, including the number of circulating cells and levels of cytokines in the blood. Mice also have a differential susceptibility to lipopolysaccharide (LPS or endotoxin)-induced endotoxic shock, depending on the administration time in the 24 h light-dark (LD...

journal_title：Chronobiology international

authors： Marpegan L,Leone MJ,Katz ME,Sobrero PM,Bekinstein TA,Golombek DA

更新日期：2009-10-01 00:00:00

abstract：:Social anxiety has recently been linked to morningness-eveningness; however, the psychological mechanisms underlying this relationship are not well known. As such, the purpose of the current study is to propose a model by which morningness-eveningness is related to social anxiety symptoms through punishment sensitivit...

journal_title：Chronobiology international

authors： Markarian SA,Gildner DJ,Pickett SM,Warnke AS

更新日期：2019-02-01 00:00:00

abstract：:This study aims to investigate independent associations of habitual sleep durations and sleep timings on weekdays and weekends with depressive symptoms in adolescents who have classes in the morning. We studied grade 7-9 students (942 males and 940 females, aged 12-15 years), who had classes in the morning, at public ...

journal_title：Chronobiology international

authors： Ojio Y,Kishi A,Sasaki T,Togo F

更新日期：2020-06-01 00:00:00

abstract：:Two different experimental models were used to test if a temporal relationship exists between the rhythm of adrenal steroid secretion and the vulnerability of the hamster reproductive system to short photoperiod exposure or to the daily afternoon injection of melatonin. In the first experiment adrenalectomized hamster...

journal_title：Chronobiology international

authors： Joshi BN,Vaughan MK,Nürnberger F,Reiter RJ

更新日期：1985-01-01 00:00:00

abstract：:Daily schedules of many organisms, including birds, are thought to affect fitness. Timing in birds is based on circadian clocks that have a heritable period length, but fitness consequences for individuals in natural environments depend on the scheduling of entrained clocks. This chronotype, i.e., timing of an individ...

journal_title：Chronobiology international

authors： Lehmann M,Spoelstra K,Visser ME,Helm B

更新日期：2012-10-01 00:00:00