Abstract:
:Correlation between systolic (SBP) and diastolic (DBP) blood pressure (BP) level and target organ damage, cardiovascular disease (CVD) risk, and long-term prognosis is much greater for ambulatory BP monitoring (ABPM) than daytime office measurements. The 2013 ABPM guidelines specified herein are based on ABPM patient outcomes studies and constitute a substantial revision of current knowledge. The asleep SBP mean and sleep-time relative SBP decline are the most significant predictors of CVD events, both individually as well as jointly when combined with other ABPM-derived prognostic markers. Thus, they should be preferably used to diagnose hypertension and assess CVD and other associated risks. Progressive decrease by therapeutic intervention of the asleep BP mean is the most significant predictor of CVD event-free interval. The 24-h BP mean is not recommended to diagnose hypertension because it disregards the more valuable clinical information pertaining to the features of the 24-h BP pattern. Persons with the same 24-h BP mean may display radically different 24-h BP patterns, ranging from extreme-dipper to riser types, representative of markedly different risk states. Classification of individuals by comparing office with either the 24-h or awake BP mean as "masked normotensives" (elevated clinic BP but normal ABPM), which should replace the terms of "isolated office" or "white-coat hypertension", and "masked hypertensives" (normal clinic BP but elevated ABPM) is misleading and should be avoided because it disregards the clinical significance of the asleep BP mean. Outcome-based ABPM reference thresholds for men, which in the absence of compelling clinical conditions are 135/85 mmHg for the awake and 120/70 mmHg for the asleep SBP/DBP means, are lower by 10/5 mmHg for SBP/DBP in uncomplicated, low-CVD risk, women and lower by 15/10 mmHg for SBP/DBP in male and female high-risk patients, e.g., with diabetes, chronic kidney disease (CKD), and/or past CVD events. In the adult population, the combined prevalence of masked normotension and masked hypertension is >35%. Moreover, >20% of "normotensive" adults have a non-dipper BP profile and, thus, are at relatively high CVD risk. Clinic BP measurements, even if supplemented with home self-measurements, are unable to quantify 24-h BP patterning and asleep BP level, resulting in potential misclassification of up to 50% of all evaluated adults. ABPM should be viewed as the new gold standard to diagnose true hypertension, accurately assess consequent tissue/organ, maternal/fetal, and CVD risk, and individualize hypertension chronotherapy. ABPM should be a priority for persons likely to have a blunted nighttime BP decline and elevated CVD risk, i.e., those who are elderly and obese, those with secondary or resistant hypertension, and those diagnosed with diabetes, CKD, metabolic syndrome, and sleep disorders.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
International Society for Chronobiology.,American Association of Medical Chronobiology and Chronotherapeutics.,Spanish Society of Applied Chronobiology, Chronotherapy, and Vascular Risk.,Spanish Society of Atherosclerosis.,Romanian Society of Indoi
10.3109/07420528.2013.750490subject
Has Abstractpub_date
2013-04-01 00:00:00pages
355-410issue
3eissn
0742-0528issn
1525-6073journal_volume
30pub_type
杂志文章abstract:BACKGROUND:Patients with mood disorders show a high dependence of behavior on the molecular characteristics of the biological clock. CLOCK rs1801260 gene polymorphism influences circadian behavior in bipolar disorder (BD), with *C carriers showing a delayed sleep onset and worse insomnia. Sleep phase delay and insomnia...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1060603
更新日期:2015-01-01 00:00:00
abstract::The course of swelling after maxillo-facial surgery was investigated by measuring the distance from the tragus to the pogonium. The post-surgical swelling does not diminish continuously, but decreases in a circaseptan periodic mode. The reactive periodicity is preferentially induced not by the injury, but by the surgi...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528409059133
更新日期:1984-01-01 00:00:00
abstract::Exposure to artificial light at night (ALAN) has become increasing common, especially in developed countries. We investigated the effect of dALAN exposure during sleep in healthy young male subjects. A total of 30 healthy young male volunteers from 21 to 29 years old were recruited for the study. They were randomly di...
journal_title:Chronobiology international
pub_type: 杂志文章,随机对照试验
doi:10.3109/07420528.2015.1108980
更新日期:2016-01-01 00:00:00
abstract::The aim of this study was to demonstrate that a possible recurrence may pertain to migraine attacks (MAs). The study was carried out by checking the personal diaries of 30 migraine sufferers ("migraineurs") who carefully annotated the date of their MA over twelve consecutive months. The group was composed of 15 males ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529009059158
更新日期:1990-01-01 00:00:00
abstract::Previous literature suggests that human behaviour and physiology are somehow altered by the moon-cycle, with particular emphasis on poorer sleep quality and increased aggressive behaviour during full moon. The latter variables can negatively impact athletes' recovery and increase the likelihood of injury resulting fro...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1483943
更新日期:2018-09-01 00:00:00
abstract::Groups of photorefractory female subtropical house sparrows, Passer domesticus, when treated with 6 weeks of a short photocycle (8L:16D) showed significant ovarian growth on their return to a long photocycle (15L:9D). A 6-hr photophase coupled with scotophase of varying durations does not terminate the refractory peri...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529009056974
更新日期:1990-01-01 00:00:00
abstract::Previous studies have demonstrated seasonal variation in the incidence of acute myocardial infarction (AMI) with an increase in cases during the winter months. However, they did not assess whether ST-elevation MI (STEMI) and non-ST-elevation MI (NSTEMI) exhibit similar changes. The object of this study was to compare ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520701800611
更新日期:2007-01-01 00:00:00
abstract::Daily schedules of many organisms, including birds, are thought to affect fitness. Timing in birds is based on circadian clocks that have a heritable period length, but fitness consequences for individuals in natural environments depend on the scheduling of entrained clocks. This chronotype, i.e., timing of an individ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2012.707159
更新日期:2012-10-01 00:00:00
abstract::This study investigated (i) blood pressure (BP), heart rate (HR), and their relation to urinary NOx and eNOS protein expression in male and female spontaneously hypertensive rats (SHR), as well as (ii) gender-dependent cardiovascular effects of nebivolol (NEB) in comparison to metoprolol (MET) in SHR. BP and HR were m...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520600827129
更新日期:2006-01-01 00:00:00
abstract::Flexible working hours can have several meanings and can be arranged in a number of ways to suit the worker and/or employer. Two aspects of "flexible" arrangement of working hours were considered: one more subjected to company control and decision (variability) and one more connected to individual discretion and auton...
journal_title:Chronobiology international
pub_type: 杂志文章,多中心研究
doi:10.1080/07420520601087491
更新日期:2006-01-01 00:00:00
abstract::Depression is a multifactorial illness that is highly prevalent among medical students (MS). Chronotypes, which reflect circadian preference in humans, as well as academic stress have been associated with depression in different populations. However, it is not known how chronotype and stress might alone or in combinat...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2016.1217230
更新日期:2016-01-01 00:00:00
abstract::The electronic health record (EHR) contains rich histories of clinical care, but has not traditionally been mined for information related to sleep habits. Here, we performed a retrospective EHR study based on a cohort of 3,652 individuals with self-reported sleep behaviors documented from visits to the sleep clinic. T...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1508152
更新日期:2018-11-01 00:00:00
abstract::Since 50-60% of the human body consists of water, the physiology of blood circulation might be affected by a full moon differently than during other days of the month. This study analyzed a potential association among lunar phases, seasonal variations, and the rate of spontaneous epistaxis. Consecutive admissions sole...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.916298
更新日期:2014-08-01 00:00:00
abstract::Light-at-night (LAN) is a worldwide problem co-distributed with breast cancer prevalence. We hypothesized that exposure to LAN is coincided with a decreased melatonin (MLT) secretion level, followed by epigenetic modifications and resulted in higher breast cancer tumors growth-rate. Accordingly, we studied the effect ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2013.842925
更新日期:2014-02-01 00:00:00
abstract::The length of the free-running period (τ) affects how an animal re-entrains after phase shifts of the light-dark (LD) cycle. Those with shorter periods adapt faster to phase advances than those with longer periods, whereas those with longer periods adapt faster to phase delays than those with shorter periods. The free...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2012.700670
更新日期:2012-10-01 00:00:00
abstract::It has frequently been reported that exposure to artificial light at night (ALAN) may cause negative health effects, such as breast cancer, circadian phase disruption and sleep disorders. Here, we reviewed the literature assessing the effects of human exposure to ALAN in order to list the health effects of various asp...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420528.2015.1073158
更新日期:2015-01-01 00:00:00
abstract::Dysregulation of the system of nitric oxide (NO)-cyclic 3',5'-guanosine monophosphate (cGMP) might be involved in the development of hypertension in transgenic hypertensive TGR(mREN2)27 (TGR) rats. The present study was performed to determine possible differences in the day-night pattern and the urinary excretion rate...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529909116860
更新日期:1999-05-01 00:00:00
abstract::This study aims to investigate independent associations of habitual sleep durations and sleep timings on weekdays and weekends with depressive symptoms in adolescents who have classes in the morning. We studied grade 7-9 students (942 males and 940 females, aged 12-15 years), who had classes in the morning, at public ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1746796
更新日期:2020-06-01 00:00:00
abstract::The 10 min psychomotor vigilance task (PVT) is commonly used in laboratory studies to assess the impact of sleep loss, sustained wakefulness, and/or time of day on neurobehavioral performance. In field settings, though, it may be impractical for participants to perform a test of this length. The aim of this study was ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520601067931
更新日期:2006-01-01 00:00:00
abstract::Workers who meet the criteria for shift work disorder (SWD) have elevated levels of risk for various health and behavioral problems. However, the impact of having SWD on shiftworkers engaged in rapid-rotation schedules is unknown. Moreover, the risk factors for the occurrence of SWD remain unclear. To clarify these is...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2012.762010
更新日期:2013-05-01 00:00:00
abstract::Plasma triglyceride (TG) levels show a clear daily rhythm, however, thus far it is still unknown whether this rhythm results from a daily rhythm in TG production, TG uptake or both. Previous studies have shown that feeding activity affects plasma TG concentrations, but it is not clear how the daily rhythm in feeding a...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1438456
更新日期:2018-07-01 00:00:00
abstract::Diurnal and seasonal rhythms of cortisol, testosterone, and DHEA were examined, as little is known about the relationship between these rhythmicities and pubertal development. Salivary samples were obtained from 60 boys and 60 girls at approximately 07:45, 08:00, 08:30, 12:00, 16:50, and 21:00 h. The participants' age...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520701649471
更新日期:2007-01-01 00:00:00
abstract::The objective of the present study was to evaluate seasonal periodicity in the prevalence of Helicobacter pylori. A prospective study was performed on 1076 consecutive patients who were investigated in our hospital over a 3-year span because of epigastric complaints. Our findings indicate a significant accumulation of...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529909016947
更新日期:1999-11-01 00:00:00
abstract::The effects of Chagas disease on the mammalian circadian system were studied in Trypanosoma cruzi-infected C57-B16J mice. Animals were inoculated with CAI or RA strains of T. cruzi or vehicle, parasitism confirmed by blood specimen visualization and locomotor activity rhythms analyzed by wheel-running recording. RA-st...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120017687
更新日期:2003-01-01 00:00:00
abstract::There is strong association between chronic kidney disease (CKD) and increased prevalence of hypertension, risk of end-organ damage, and cardiovascular disease (CVD). Non-dipping, as determined by ambulatory blood pressure (BP) monitoring (ABPM), is frequent in CKD and has also been consistently associated with increa...
journal_title:Chronobiology international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.3109/07420528.2012.703083
更新日期:2013-03-01 00:00:00
abstract::The first aim of the study was to assess clock-time patterning of work-related injuries (WRIs) of firemen (FM) of Saône et Loire-71 (France) during the 4-yr span of 1 January 2004 to 31 December 2007. FM of this service are legally required to log every WRI and seek its evaluation by the medical service, whether the W...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.603170
更新日期:2011-10-01 00:00:00
abstract::The authors estimated the benchmark durations (BMDs) and their 95% lower confidence limit (BMDL) for the reference duration of shiftwork for weight gain. A 14-yr prospective cohort study was conducted in male workers at a Japanese steel company (n = 7254) who had received annual health check-ups between 1991 and 2005....
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2010.516045
更新日期:2010-10-01 00:00:00
abstract::Performance alterations in executive function have been studied as potential endophenotypes for several neuropsychiatric diseases. Planning is an important component of executive function and has been shown to be affected in diseases such as attention deficit hyperactivity disorder, schizophrenia, obsessive-compulsive...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1014096
更新日期:2015-06-01 00:00:00
abstract::The pineal hormone melatonin is potentially useful in the treatment of disorders, especially sleep disorders, associated with circadian rhythm disturbance. We have examined its effects on sleep, mood, and behaviour in a double-blind, placebo-controlled study of a small group of police officers working spans of seven s...
journal_title:Chronobiology international
pub_type: 临床试验,杂志文章
doi:10.3109/07420529309064485
更新日期:1993-10-01 00:00:00
abstract::Animal and human studies demonstrate anatomical and functional links between the vestibular nuclei and the circadian timing system. This promotes the hypothesis of a circadian rhythm of vestibular function. The objective of this study was to evaluate the vestibular function through the vestibulo-ocular reflex using a ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1835941
更新日期:2021-01-01 00:00:00