Abstract:
:The appropriate time and place for sleep and waking are important factors for survival. Sleep and waking, rest and activity, flight and fight, feeding, and reproduction are all organized in relation to the day and night. A biological clock, the suprachiasmatic nucleus (SCN), synchronized by photic influences and other environmental cues, provides an endogenous timing signal that entrains circadian body rhythms and is complemented by a homeostatic sleep pressure factor. Cholinergic, catecholaminergic, serotonergic, and histaminergic nuclei control wakefulness and mutually interact with the SCN as well as sleep- and wake-promoting neurons in the hypothalamus to form a bistable switch that controls the timing of behavioral state transitions. Hypocretin neurons integrate circadian-photic and nutritional-metabolic influences and act as a conductor in the aminergic orchestra. Their loss causes narcolepsy, a disease conferring the inability to separate sleep and waking. Their role in appetitive behavior, stress, and memory functions is important to our understanding of addiction and compulsion.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Selbach O,Haas HLdoi
10.1080/07420520500545961subject
Has Abstractpub_date
2006-01-01 00:00:00pages
63-70issue
1-2eissn
0742-0528issn
1525-6073pii
P107276J54223016journal_volume
23pub_type
杂志文章,评审abstract::Since 50-60% of the human body consists of water, the physiology of blood circulation might be affected by a full moon differently than during other days of the month. This study analyzed a potential association among lunar phases, seasonal variations, and the rate of spontaneous epistaxis. Consecutive admissions sole...
journal_title:Chronobiology international
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journal_title:Chronobiology international
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journal_title:Chronobiology international
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journal_title:Chronobiology international
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journal_title:Chronobiology international
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