Melatonin shifts human circadian rhythms according to a phase-response curve.

abstract：:The rods in the retina are responsible for night vision, whereas the cone system enables day vision. We studied whether rod function in humans exhibits an endogenous circadian rhythm and if changes occur in conditions of prolonged darkness. Seven healthy subjects (mean age+/-SD: 25.6+/-12.3 yr) completed a 4.5-day pro...

journal_title：Chronobiology international

authors： Danilenko KV,Plisov IL,Wirz-Justice A,Hebert M

更新日期：2009-01-01 00:00:00

abstract：:Eveningness and sleep disturbances are considered as markers of Bipolar Disorder (BD) and influence mood and emotional or behavioral states. This study investigates the associations between circadian markers and sleep quality on residual depressive symptoms and inhibition/activation dimensions during the euthymic phas...

journal_title：Chronobiology international

authors： Caruso D,Meyrel M,Krane-Gartiser K,Benard V,Benizri C,Brochard H,Geoffroy PA,Gross G,Maruani J,Prunas C,Yeim S,Palagini L,Dell'Osso L,Leboyer M,Bellivier F,Etain B

更新日期：2020-01-01 00:00:00

abstract：:We analyzed the effect of natural solar insolation and artificial photoperiodic conditions on melatonin MT1 receptor expression of a tropical rodent, Funambulus pennanti. Melatonin mediates reproductive and circadian responses and regulates the production of a large number of cytokines, including interleukin-2 (IL-2),...

journal_title：Chronobiology international

authors： Lahiri S,Haldar C

更新日期：2009-12-01 00:00:00

abstract：:In Cushing's syndrome, the cortisol rhythm is impaired and can be associated with the disruption in the rhythmic expression of clock genes. In this study, we evaluated the expression of CLOCK, BMAL1, CRY1, CRY2, PER1, PER2, PER3 genes in peripheral blood leukocytes of healthy individuals (n = 13) and Cushing's disease...

journal_title：Chronobiology international

authors： Soares VR,Silva Martins C,Martinez EZ,Araujo LD,Roa SLR,Silva LR,Moreira AC,De Castro M

更新日期：2020-06-01 00:00:00

abstract：:The increased prevalence of circadian disruptions due to abnormal coupling between internal and external time makes the detection of circadian phase in humans by ambulatory recordings a compelling need. Here, we propose an accurate practical procedure to estimate circadian phase with the least possible burden for the ...

journal_title：Chronobiology international

authors： Bonmati-Carrion MA,Middleton B,Revell V,Skene DJ,Rol MA,Madrid JA

更新日期：2014-02-01 00:00:00

abstract：:The objective of the present study was to evaluate seasonal periodicity in the prevalence of Helicobacter pylori. A prospective study was performed on 1076 consecutive patients who were investigated in our hospital over a 3-year span because of epigastric complaints. Our findings indicate a significant accumulation of...

journal_title：Chronobiology international

authors： Raschka C,Schorr W,Koch HJ

更新日期：1999-11-01 00:00:00

abstract：:The aim of this study was to demonstrate that a possible recurrence may pertain to migraine attacks (MAs). The study was carried out by checking the personal diaries of 30 migraine sufferers ("migraineurs") who carefully annotated the date of their MA over twelve consecutive months. The group was composed of 15 males ...

journal_title：Chronobiology international

authors： Cugini P,Romit A,Di Palma L,Giacovazzo M

更新日期：1990-01-01 00:00:00

abstract：:In this study, we aimed to show how age affects hibernation in the Syrian hamster. Experimentally, we used 30 male animals differing in age. The old animals were 20 months of age and the adults were 8 months of age at the end of the test. The young animals were 3 weeks old at the start of testing and 5 months old at t...

journal_title：Chronobiology international

authors： Terada A,Ibuka N

更新日期：2000-09-01 00:00:00

abstract：:Four healthy non obese young volunteers were observed for a 24-hr period, every other month, over the course of one year. Tolbutamide was injected i.v. each day of the experiment every four hours. Tolbutamide-induced insulin secretion (T.I.I.S.) was evaluated by planimetrically measuring insulin areas above basal leve...

journal_title：Chronobiology international

authors： Del Ponte A,Guagnano MT,Sensi S

更新日期：1984-01-01 00:00:00

abstract：:Night shiftworkers often complain of disturbed sleep during the day. This could be partly caused by morning sunlight exposure during the commute home, which tends to maintain the circadian clock on a daytime rhythm. The circadian clock is most sensitive to the blue portion of the visible spectrum, so our aim was to de...

journal_title：Chronobiology international

authors： Sasseville A,Benhaberou-Brun D,Fontaine C,Charon MC,Hebert M

更新日期：2009-07-01 00:00:00

abstract：:Earlier we reported that in a number of experiments pineal melatonin production in rats under constant laboratory conditions displayed seasonal rhythms but subsequently were not always able to confirm this. Since there was no indication under which conditions such rhythms may be present, we performed four consecutive ...

journal_title：Chronobiology international

authors： Bartsch H,Mecke D,Probst H,Küpper H,Seebald E,Salewski L,Stehle T,Bartsch C

更新日期：2012-10-01 00:00:00

abstract：:The circadian clock regulates the daily rhythms of several physiological and behavioral processes. Disruptions in clock genes have been associated with obesity and related comorbidities. This study aimed to analyze the association of DNA methylation signatures at circadian rhythm pathway genes with body mass index (BM...

journal_title：Chronobiology international

authors： Ramos-Lopez O,Samblas M,Milagro FI,Riezu-Boj JI,Crujeiras AB,Martinez JA,Project M

更新日期：2018-07-01 00:00:00

abstract：:The properties of the circadian photoperiodic oscillator have been investigated in detail only in the Japanese quail. While the study of the quail is clearly very important, one cannot simply assume that other species, especially passerines that seem to have a different circadian organization than quail, function the ...

journal_title：Chronobiology international

authors： Singh S,Misra M,Rani S,Kumar V

更新日期：2002-09-01 00:00:00

abstract：:Chronic sympathetic denervation of the pineal gland by bilateral removal of the superior cervical ganglia (SCG) was performed on female rats 30 days before impregnation. The offspring, maintained in the dark from birth, had disruption of the malate dehydrogenase circadian rhythm in the testes at 25 days of age. A dail...

journal_title：Chronobiology international

authors： Vermouth NT,Carriazo CS,Gallará RV,Carpentieri AR,Bellavía SL

更新日期：1995-02-01 00:00:00

abstract：:Sleep-related problems, such as symptoms of insomnia, daytime sleepiness, shorter sleep duration, or a delayed sleep-wake schedule, are known to be risk factors for depression. In general, depression is more prevalent in women than in men, but sleep-related problems do not necessarily show similar gender predominance....

journal_title：Chronobiology international

authors： Morita Y,Sasai-Sakuma T,Asaoka S,Inoue Y

更新日期：2015-01-01 00:00:00

abstract：:The effects of Chagas disease on the mammalian circadian system were studied in Trypanosoma cruzi-infected C57-B16J mice. Animals were inoculated with CAI or RA strains of T. cruzi or vehicle, parasitism confirmed by blood specimen visualization and locomotor activity rhythms analyzed by wheel-running recording. RA-st...

journal_title：Chronobiology international

authors： Fernández Alfonso T,Celentano AM,Gonzalez Cappa SM,Golombek DA

更新日期：2003-01-01 00:00:00

abstract：:Chronotypes have been associated with psychopathology. The eveningness chronotype has been consistently linked with depressed states or depressive disorder, but the underlying mechanism remains unclear. Prior studies have shown associations between chronotype and personality traits that are linked to depression (e.g. ...

journal_title：Chronobiology international

authors： Antypa N,Verkuil B,Molendijk M,Schoevers R,Penninx BWJH,Van Der Does W

更新日期：2017-01-01 00:00:00

abstract：:Fourteen healthy subjects have been studied in an isolation unit while living on a 30h "day" (20h awake, 10h asleep) for 14 (solar) days but while aware of real time. Waking activities were sedentary and included reading, watching television, and so forth. Throughout, regular recordings of rectal temperature were made...

journal_title：Chronobiology international

authors： Minors DS,Folkard S,Waterhouse JM

更新日期：1996-10-01 00:00:00

abstract：:The first aim of the study was to assess clock-time patterning of work-related injuries (WRIs) of firemen (FM) of Saône et Loire-71 (France) during the 4-yr span of 1 January 2004 to 31 December 2007. FM of this service are legally required to log every WRI and seek its evaluation by the medical service, whether the W...

journal_title：Chronobiology international

authors： Riedel M,Berrez S,Pelisse D,Brousse E,Forget C,Marlot M,Smolensky MH,Touitou Y,Reinberg A

更新日期：2011-10-01 00:00:00

abstract：:Changes in the free-running period of the circadian rhythms of hamsters occur after single nonphotic events such as a 3-h pulse of running induced by being put in a novel wheel. These changes are mostly in the direction of longer periods, and can exceed 0.2 h; the magnitude of the effect depends on the circadian phase...

journal_title：Chronobiology international

authors： Mrosovsky N

更新日期：1993-08-01 00:00:00

abstract：:Daily schedules of many organisms, including birds, are thought to affect fitness. Timing in birds is based on circadian clocks that have a heritable period length, but fitness consequences for individuals in natural environments depend on the scheduling of entrained clocks. This chronotype, i.e., timing of an individ...

journal_title：Chronobiology international

authors： Lehmann M,Spoelstra K,Visser ME,Helm B

更新日期：2012-10-01 00:00:00

abstract：:This retrospective study tested the hypothesis that disease control and treatment-related toxicity in patients undergoing high-dose radiotherapy (HDRT) for prostate cancer varies in a circadian manner. Patients with localized prostate adenocarcinoma receiving HDRT (median 78 Gy) to the prostate and involved seminal ve...

journal_title：Chronobiology international

authors： Hsu FM,Hou WH,Huang CY,Wang CC,Tsai CL,Tsai YC,Yu HJ,Pu YS,Cheng JC

更新日期：2016-01-01 00:00:00

abstract：:In this paper, a peptic ulcer is considered from the perspective that it is representative of a heterogeneous group of multifactorial determined or influenced disorders having a common pathomorphologic expression. This heterogeneity involves pathophysiological attributes, including both functional (including secretory...

journal_title：Chronobiology international

authors： Tarquini B,Vener KJ

更新日期：1987-01-01 00:00:00

abstract：:Social anxiety has recently been linked to morningness-eveningness; however, the psychological mechanisms underlying this relationship are not well known. As such, the purpose of the current study is to propose a model by which morningness-eveningness is related to social anxiety symptoms through punishment sensitivit...

journal_title：Chronobiology international

authors： Markarian SA,Gildner DJ,Pickett SM,Warnke AS

更新日期：2019-02-01 00:00:00

abstract：:Julien-Joseph Virey (1775-1846) held the position of pharmacist-in-chief at the Val-de-Grâce, a military hospital. He was an innovative pharmacist, naturalist, anthropologist, and philosopher and a prolific author. His writings encompassed a wide range of topics, although many of his ideas were sometimes harshly quest...

journal_title：Chronobiology international

authors： Reinberg AE,Lewy H,Smolensky M

更新日期：2001-03-01 00:00:00

abstract：:Exposure to artificial light at night (ALAN) has become increasing common, especially in developed countries. We investigated the effect of dALAN exposure during sleep in healthy young male subjects. A total of 30 healthy young male volunteers from 21 to 29 years old were recruited for the study. They were randomly di...

journal_title：Chronobiology international

authors： Cho CH,Lee HJ,Yoon HK,Kang SG,Bok KN,Jung KY,Kim L,Lee EI

更新日期：2016-01-01 00:00:00

abstract：:The study aimed at testing chronotype and gender differences in the time of day when humans feel the greatest need for sex and the time of day they actually undertake sexual activity. A Polish sample of 565 participants aged between 18 and 57 was tested. In females, regardless of chronotype, the greatest need for sex ...

journal_title：Chronobiology international

authors： Jankowski KS,Díaz-Morales JF,Randler C

更新日期：2014-10-01 00:00:00

abstract：:Light is an important environmental stimulus for the entrainment of the circadian clock and for increasing alertness. The intrinsically photosensitive ganglion cells in the retina play an important role in transferring this light information to the circadian system and they are elicited in particular by short-waveleng...

journal_title：Chronobiology international

authors： Giménez MC,Beersma DG,Bollen P,van der Linden ML,Gordijn MC

更新日期：2014-06-01 00:00:00

abstract：:Melatonin, an essential pineal hormone, acts as a marker of the circadian clock that regulates biological rhythms in animals. The effects of exogenous melatonin on the circadian system of nocturnal rodents have been extensively studied; however, there is a paucity of studies on the phase-resetting characteristics of m...

journal_title：Chronobiology international

authors： Soni SK,Kumar D,Singaravel M

更新日期：2020-05-01 00:00:00

abstract：:The aim of this study was to examine the impact of brief, unscheduled naps during work periods on alertness and vigilance in coastal pilots along the Great Barrier Reef. On certain routes, the duration of the work period can extend well beyond 24 h. Seventeen coastal pilots volunteered for the study, representing almo...

journal_title：Chronobiology international

authors： Ferguson SA,Lamond N,Kandelaars K,Jay SM,Dawson D

更新日期：2008-04-01 00:00:00