Abstract:
:In this paper, a peptic ulcer is considered from the perspective that it is representative of a heterogeneous group of multifactorial determined or influenced disorders having a common pathomorphologic expression. This heterogeneity involves pathophysiological attributes, including both functional (including secretory and motility events and their respective driving mechanisms) and morphologic alterations that relate to mucosal resistance. Patients with duodenal ulcer (DU) have been observed to exhibit alterations, in comparison to normal subjects, in the circadian rhythm characteristics of several gastrointestinal functions. Prominent among these are altered amplitudes of several circadian-organized gastric variables, such as intragastric pH, gastrin, pepsinogen and gastric mitotic index. With respect to any given variable, a reduced group amplitude (a measure of one-half the peak-trough difference of a 24-hr rhythm) could signify an increased dispersion of acrophases (the location of the peak of a circadian rhythm along the 24-hr time scale) reflecting interindividual variation in synchronization schedules, sleep-wake patterns, or chronobiologic alterations. A reduced interindividual amplitude further supports the concept of the heterogeneity of peptic disease. A decrease in the intraindividual amplitude of certain gastric rhythms implies an altered temporal pattern over the 24 hr. This is consistent with the hypothesis of a decrease in the amount of time available for recovery of a given function or set of integrated functions, and hence, increased susceptibility to mucosal injury. Normal high-amplitude variation in gastrointestinal functioning over the 24 hr appears to be required for natural restoration of the gut.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Tarquini B,Vener KJdoi
10.1080/07420528709078511subject
Has Abstractpub_date
1987-01-01 00:00:00pages
75-89issue
1eissn
0742-0528issn
1525-6073journal_volume
4pub_type
杂志文章,评审abstract::The objective of the present study was to evaluate the sexual behavior of male rats kept under constant laboratory conditions for one entire year. A total of 213 sexually-inexperienced, male Wistar rats were maintained in controlled environmental conditions from birth. Depending the month in which they reached the age...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1715997
更新日期:2020-02-01 00:00:00
abstract::ST8SIA2 and NCAM1 are functionally related genes forming polysialic acid (PSA) - neural cell adhesion molecule (NCAM) complex in suprachiasmatic nucleus (SCN), the regulating site of circadian biological rhythm. In this study, the relationship of ST8SIA2 and NCAM1 with circadian and seasonal rhythms of human behavior ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2017.1410827
更新日期:2018-03-01 00:00:00
abstract::High fat diet (HFD) consumption alters the synchronized circadian timing system resulting in harmful loss, gain or shift of transcriptional oscillations. The aryl hydrocarbon receptor (AhR) shares structural homology to clock genes, containing both PAS domains and basic helix-loop helix structural motifs, allowing for...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2016.1256298
更新日期:2017-01-01 00:00:00
abstract::The effects of Chagas disease on the mammalian circadian system were studied in Trypanosoma cruzi-infected C57-B16J mice. Animals were inoculated with CAI or RA strains of T. cruzi or vehicle, parasitism confirmed by blood specimen visualization and locomotor activity rhythms analyzed by wheel-running recording. RA-st...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120017687
更新日期:2003-01-01 00:00:00
abstract::Genetic risk is a primary contributing factor to the predisposition of a newborn child to elevated blood pressure later in life. An index of this factor is needed to assess in the neonate the success or failure of preventive interventions instituted for the pregnant women. This index could be based on characteristics ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529309073890
更新日期:1993-06-01 00:00:00
abstract::The circadian melatonin rhythm is highly reproducible and generally not easily altered. The few perturbations that are capable of significantly changing either the amplitude or the pattern of the 24-h melatonin rhythm are summarized herein. Aging alters cyclic melatonin production by decreasing the amplitude of the no...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420529209064541
更新日期:1992-08-01 00:00:00
abstract::Recently, attention has been focused on the relationship among circadian typology, psychiatric symptoms, and personality traits. This study analyzes the influence of circadian typology on psychological distress, and the sensation-seeking personality trait. Five hundred seventeen college students (173 males), aged 17 t...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2013.790044
更新日期:2013-08-01 00:00:00
abstract::In the contemporary era, when life habits are largely determined by social needs and individual preferences, sleep is nevertheless affected by seasonal environmental changes. Japan has large seasonal and geographical alterations of photoperiod and climate. Japan does not adopt the daylight saving time (DST) system, ma...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1443118
更新日期:2018-07-01 00:00:00
abstract::The intrinsic circadian clock requires photoentrainment to synchronize the 24-hour solar day. Therefore, light stimulation is an important component of chronobiological research. Currently, the chronobiological research field overwhelmingly uses photopic illuminance that is based on the luminous efficiency function, V...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.966269
更新日期:2015-03-01 00:00:00
abstract::Several substances change the period length of the circadian oscillator in the laminar pulvinus of Phaseolus coccineus L. if offered continuously via the transpiration stream to the isolated leaves in continuous light and constant temperature. The osmotica mannitol and PEG 6000 (polyethylene glycol) lengthen the circa...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528509055537
更新日期:1985-01-01 00:00:00
abstract::The ventromedial hypothalamic nucleus (VMH) regulates various autonomic, endocrine, and behavioral activities. These activities show annual changes, and the pineal gland is involved in their adjustment to environmental cues. Therefore, this study investigated whether the VMH belongs to the effector structures of the p...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100101028
更新日期:2000-01-01 00:00:00
abstract::Light is necessary for life, and artificial light improves visual performance and safety, but there is an increasing concern of the potential health and environmental impacts of light. Findings from a number of studies suggest that mistimed light exposure disrupts the circadian rhythm in humans, potentially causing fu...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1527773
更新日期:2019-02-01 00:00:00
abstract::The objectives of the study were to investigate the associations between night work and disability pension (DP) due to all causes, cardiovascular (CVD), mental, and other diagnoses, adjusting for familial confounding. The material of the study included comprehensive survey data on 27 165 Swedish twins born in 1935-195...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2017.1399137
更新日期:2018-02-01 00:00:00
abstract::Social anxiety has recently been linked to morningness-eveningness; however, the psychological mechanisms underlying this relationship are not well known. As such, the purpose of the current study is to propose a model by which morningness-eveningness is related to social anxiety symptoms through punishment sensitivit...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1529679
更新日期:2019-02-01 00:00:00
abstract::Good sleep hygiene practices, including consistent bedtimes and 7-9 h of sleep/night, are theorized to benefit educational learning. However, individuals differ in how much sleep they need, as well as in their chronotype preference. Therefore, some students may be more vulnerable to the cognitive effects of sleep loss...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2018.1539401
更新日期:2019-03-01 00:00:00
abstract::The focus of this study was on daytime and nighttime sleep and wakefulness during the peak age for Sudden Infant Death Syndrome (SIDS), two to four months, to determine whether there are differences between at-risk for SIDS (R) and control (C) infants. Such differences may provide insight on the frequent occurrence of...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520600921070
更新日期:2006-01-01 00:00:00
abstract::Populations working night shift are high risk for diet-related chronic illness which may result from circadian misalignment. Studies documenting nutritional habits among night shift workers have relied on inaccurate approximations of dietary intake. The primary purpose of this pilot study was to gather feasibility inf...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2020.1822857
更新日期:2020-09-28 00:00:00
abstract::A synopsis of the effects of exercise on the circadian system in nocturnal rodents is followed by a review of the few studies investigating the influence of exercise on the human circadian system. It is premature to make specific recommendations about using exercise to promote synchronization in people because of the ...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420529709001157
更新日期:1997-03-01 00:00:00
abstract::In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors. Blood pressure was measured by the oscillometric method using the blood pressure monitor 90202 from SpaceLabs, Inc. The measurements were taken from 06:00 to 22:00 h...
journal_title:Chronobiology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/07420529109059177
更新日期:1991-01-01 00:00:00
abstract::The construction of time-specified reference limits requires systematic sampling in clinical health, particularly for those variables characterized by a circadian rhythm of large amplitude, as it is the case for blood pressure (BP). For the detection of false negatives, tolerance intervals (limits that will include at...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100101064
更新日期:2000-07-01 00:00:00
abstract::Circadian phase dependency in pharmacokinetics and hemodynamic effects on blood pressure and heart rate of different galenic formulations of nifedipine (immediate-release, sustained-release, and i.v. solution) were studied in healthy subjects or in hypertensive patients. Pharmacokinetics of immediate-release but not s...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529109059184
更新日期:1991-01-01 00:00:00
abstract::The circadian clock of man and mammals shows a hierarchic organization. The master clock, located in the suprachiasmatic nuclei (SCN), controls peripheral oscillators distributed throughout the body. Rhythm generation depends on molecular clockworks based on transcriptional/translational interaction of clock genes. Nu...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.949735
更新日期:2015-02-01 00:00:00
abstract::Despite its clinical importance, the issue of the diurnal time course of sleepiness and performance in children remains largely unexplored. The objective of this study is to draw a profile of daytime subjective sleepiness and performance, at simple and complex tasks, in a cohort of Italian primary school children.To t...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2016.1178274
更新日期:2016-01-01 00:00:00
abstract::Previous research points to some inappropriate nutritional habits among nurses working night shifts. However, the knowledge of specific nutritional components of their diet has been limited. In the present study, we aimed to investigate the association between rotating night shifts of nurses and midwives and their usu...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1602051
更新日期:2019-07-01 00:00:00
abstract::Circadian changes in activities and electrophoretic pattern of the intestinal brushborder enzymes alkaline phosphatase (EC 3.1.3.1), isomaltase (EC 3.2.1.10) and sucrase (EC 3.2.1.26) of normal rats and of rats with a lesion of the dorsomedial hypothalamus (DMH-rats) were studied. In contrast to the rhythm found in no...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528509055548
更新日期:1985-01-01 00:00:00
abstract::The effect of varying the dose-delivery time within a 24 h period (12:12 light-dark cycle) on the immunomodulatory properties of corn oil administered by gavage to 120 B6C3F1 female mice was investigated. Mice, housed in six separate boxes equipped with timers to regulate light onset and offset (staggered by 4 h incre...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529909019085
更新日期:1999-03-01 00:00:00
abstract::It has frequently been reported that exposure to artificial light at night (ALAN) may cause negative health effects, such as breast cancer, circadian phase disruption and sleep disorders. Here, we reviewed the literature assessing the effects of human exposure to ALAN in order to list the health effects of various asp...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420528.2015.1073158
更新日期:2015-01-01 00:00:00
abstract::Seasonal Affective Disorder (SAD) is a condition of regularly occurring depressions in winter with a remission the following spring or summer. In addition to depressed mood, the patients tend to experience increased appetite and an increased duration of sleep during the winter. SAD is a relatively common condition, af...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.1081/cbi-120019310
更新日期:2003-03-01 00:00:00
abstract::In situ growth of Sphagnum riparium Ångstr. shoots were monitored during the 2015 and 2016 growing seasons in Karelia, Russia. It was established that shoot growth rates fluctuated with a period of around 30 days, that is, showed a circatrigintan rhythm. Such rhythms from mosses have not been previously reported. Corr...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2017.1329208
更新日期:2017-01-01 00:00:00
abstract::Visual sensitivity rhythm has been assessed by several authors in animals. It shows an intrinsic circadian rhythm of some retinal mechanisms that could account for fluctuating sensitivity to light during the day in these species. However, very little is known concerning a possible circadian rhythm of visual sensitivit...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529709040540
更新日期:1997-01-01 00:00:00