Abstract:
:Most research papers published in Chronobiology International report the findings of investigations conducted on laboratory animals and human beings. The Journal, its editors and the publication committee endorse the compliance of investigators to the principles of the Declaration of Helsinki of the World Medical Association relating to the conduct of ethical research on human beings and the Guide for the Care and Use of Laboratory Animals of the Institute for Laboratory Animal Research of the National Research Council relating to the conduct of ethical research on laboratory and other animals. Chronobiology International requires that submitted manuscripts reporting the findings of human and animal research conform to the respective policy and mandates of the Declaration of Helsinki and the Guide for the Care and Use of Laboratory Animals. The peer review of manuscripts will thus include judgment of whether or not the involved research methods conform to the standards of good research practice. This article outlines the basic expectations for the methods of human and animal biological rhythm research, both from the perspective of the fundamental criteria necessary for quality chronobiology investigation and from the perspective of humane and ethical research on human beings and animals.
journal_name
Chronobiol Intjournal_title
Chronobiology internationalauthors
Touitou Y,Portaluppi F,Smolensky MH,Rensing Ldoi
10.1081/cbi-120030045subject
Has Abstractpub_date
2004-01-01 00:00:00pages
161-70issue
1eissn
0742-0528issn
1525-6073journal_volume
21pub_type
杂志文章abstract::Seasonal variations have been described in humans in several variables such as sleep, mood, appetite, food preferences, or body weight. We hypothesized that these variations could also influence the decrease in body weight rate in patients submitted to body weight loss interventions. Thus, here we tested the variation...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1580716
更新日期:2019-05-01 00:00:00
abstract::This study investigated (i) blood pressure (BP), heart rate (HR), and their relation to urinary NOx and eNOS protein expression in male and female spontaneously hypertensive rats (SHR), as well as (ii) gender-dependent cardiovascular effects of nebivolol (NEB) in comparison to metoprolol (MET) in SHR. BP and HR were m...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520600827129
更新日期:2006-01-01 00:00:00
abstract::Behavior, physiological functions and cognitive performance change over the time of the day. These daily rhythms are either externally driven by rhythmic environmental cues such as the light/dark cycle (masking) or controlled by an internal circadian clock, the suprachiasmatic nucleus (SCN), which can be entrained to ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.956218
更新日期:2015-02-01 00:00:00
abstract::The aim of the study was to evaluate the influence of chronotype (morning-type versus evening-type) living in a fixed sleep-wake schedule different from one's preferred sleep schedules on the time course of neurobehavioral performance during controlled extended wakefulness. The authors studied 9 morning-type and 9 eve...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2011.590623
更新日期:2011-07-01 00:00:00
abstract::Nineteen adult cancer patients each received 6-10 monthly treatments of doxorubicin and cisplatin. For 24-30 hr before each treatment, recumbent pulse was measured. Treatment was stopped for disease progression or when a total doxorubicin dose of 550 mg/m2 was reached. No patient developed congestive heart failure (CH...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528409059119
更新日期:1984-01-01 00:00:00
abstract::Two different experimental models were used to test if a temporal relationship exists between the rhythm of adrenal steroid secretion and the vulnerability of the hamster reproductive system to short photoperiod exposure or to the daily afternoon injection of melatonin. In the first experiment adrenalectomized hamster...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528509055541
更新日期:1985-01-01 00:00:00
abstract::Light-at-night (LAN) is a worldwide problem co-distributed with breast cancer prevalence. We hypothesized that exposure to LAN is coincided with a decreased melatonin (MLT) secretion level, followed by epigenetic modifications and resulted in higher breast cancer tumors growth-rate. Accordingly, we studied the effect ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2013.842925
更新日期:2014-02-01 00:00:00
abstract::The circadian melatonin rhythm is highly reproducible and generally not easily altered. The few perturbations that are capable of significantly changing either the amplitude or the pattern of the 24-h melatonin rhythm are summarized herein. Aging alters cyclic melatonin production by decreasing the amplitude of the no...
journal_title:Chronobiology international
pub_type: 杂志文章,评审
doi:10.3109/07420529209064541
更新日期:1992-08-01 00:00:00
abstract::The prevalence of delayed sleep phase syndrome (DSPS) has been estimated to be quite low. Although no genetic inheritance pattern has been described, it has been reported that close to 50% of DSPS patients have biological relatives with similar symptoms. A pedigree of one extended family with symptoms suggestive of DS...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100107518
更新日期:2001-09-01 00:00:00
abstract::In two experiments, triazolam (2.5 and 1.5 mg/animal) failed to significantly enhance the rate of reentrainment of hamsters (Mesocricetus auratus) to an 8-hr advance of their light-dark cycle. Evidently the phase-shifting effects of triazolam are not robust. The animals did not run much in their wheels in response to ...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529009056952
更新日期:1990-01-01 00:00:00
abstract::Fatigue is an increasingly noted factor in road accidents. The ability to predict and be aware of impairment in terms of driving capability is important for potential legal liability and road safety. However, to date, there have been few studies that have investigated the accuracy of individuals in predicting how safe...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520601083391
更新日期:2006-01-01 00:00:00
abstract::Previous studies have reported sex differences in the pathophysiology of hypertension and responses to blood pressure (BP)-lowering medications. Moreover, men exhibit typically higher BP than women, the differences being greater for systolic (SBP) than diastolic (DBP) BP. These differences become apparent during adole...
journal_title:Chronobiology international
pub_type: 杂志文章,随机对照试验
doi:10.3109/07420528.2012.701487
更新日期:2013-03-01 00:00:00
abstract::Twenty-four different laboratory parameters including the phagocytic activity (phagocytic index) of polymorphonuclear leukocytes (PMNs) and various hematologic variables were investigated in 13 young healthy men during Spring 1988 in Munich, Germany. Venous blood of these volunteers was obtained under standardized con...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529209064514
更新日期:1992-01-01 00:00:00
abstract::Therapy with oral anticoagulants (OACs) is a risk factor for cerebral hemorrhage (CH). Although different studies have been undertaken to investigate the timing of the onset of major cardiovascular events, no data exist on temporal patterns of the onset of CH in subjects treated with OACs. The aim of this study is to ...
journal_title:Chronobiology international
pub_type: 杂志文章,多中心研究
doi:10.3109/07420528.2015.1133636
更新日期:2016-01-01 00:00:00
abstract::In previous research, it was determined that the altitude of origin altered the parameters of photic entrainment and free-running rhythmicity of adult locomotor activity of the high-altitude Himalayan (haH) strain (Hemkund-Sahib, 4121 m above sea level) of Drosophila helvetica compared to the low-altitude Himalayan (l...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520701649448
更新日期:2007-01-01 00:00:00
abstract::This study aimed to verify the prevalence and factors associated with excessive daytime sleepiness (EDS) among adolescents. In all, 1.132 people participated. They were aged between 14 and 19 years, of both sexes and they came from a city in southern Brazil. Many socio-demographic variables were collected (sex, age gr...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1633661
更新日期:2019-09-01 00:00:00
abstract::In the free-running circadian locomotor activity rhythm of a 7-year-old male owl monkey (Aotus lemurinus griseimembra) kept under constant light and climatic conditions (LL 0.2 lux, 25 degrees C +/- 1 degrees C, 60 +/- 5% relative humidity [RH]), a second rhythm component developed that showed strong relative coordina...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-100101039
更新日期:2000-03-01 00:00:00
abstract::Although several studies of glia have examined glial fibrillary acid protein (GFAP) and its relationship to the circadian rhythms of different organisms, they have not explored the daily GFAP oscillations in the putative pacemakers of the crayfish Procambarus clarkii or in other crustaceans. In this study we investiga...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2015.1071385
更新日期:2015-01-01 00:00:00
abstract::The importance of circadian clocks in the regulation of adult physiology in mammals is well established. In contrast, the ontogenesis of the circadian system and its role in embryonic development are still poorly understood. Although there is experimental evidence that the clock machinery is present prior to birth, da...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2014.986576
更新日期:2015-04-01 00:00:00
abstract::It has been previously documented that aspirin induced gastric injury of healthy male volunteers was greater in the morning than in the evening. We have also reported that fasting gastric acid secretion rates and gastric retention times for solids were lower in the morning hours of the circadian cycle. We hypothesized...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528809067784
更新日期:1988-01-01 00:00:00
abstract::Despite research indicating that sleep disorders influence reproductive health, the effects of sleep on reproductive hormone concentrations are poorly characterized. We prospectively followed 259 regularly menstruating women across one to two menstrual cycles (the BioCycle Study, 2005-2007), measuring fasting serum ho...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2019.1694938
更新日期:2020-02-01 00:00:00
abstract::Loratadine is a second-generation histamine H(1)-receptor antagonist used in the treatment of allergic diseases. The aim of the study was to assess whether lethal toxicity and motor incoordination (neurotoxicity) of loratadine is circadian rhythm-dependent. A total of 210 male Swiss mice, aged 10 wk, were synchronized...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/CBI-200062369
更新日期:2005-01-01 00:00:00
abstract::The circalunidian-clock hypothesis is a formulation describing the means by which the tide-associated rhythms of intertidal organisms are generated. The postulate was described in a 1995 article in this journal (12:299-310). A recent paper published here (13:153-62) by Prof. Ernest Naylor challenges the validity of th...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529709001455
更新日期:1997-07-01 00:00:00
abstract::This study investigates if the serotoninergic system plays a role in chronotoxic effects of the anticancer agent oxaliplatin (l-OHP). Four groups of female rats (120 in total) synchronized with light-dark (12 h:12 h) were treated with: (i) saline, (ii) para-chlorophenylalanine (pCPA, an inhibitor of serotonin biosynth...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1081/cbi-120015957
更新日期:2002-11-01 00:00:00
abstract::Intense artificial light can phase-shift circadian rhythms and improve performance, sleep, and well-being during shiftwork simulations. In real shiftworkers, however, exposure to sunlight and other time cues may decrease the efficacy of light treatment, and occupational and family responsibilities may make it impracti...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420529509064509
更新日期:1995-04-01 00:00:00
abstract::Circadian rhythms of plasma insulin, cortisol, and glucose concentrations were examined in scotosensitive (reproductively sensitive to inhibitory effects of short daylengths) and scotorefractory male and female Syrian hamsters (Mesocricetus auratus) maintained on short (LD 10:14) and long (LD 14:10) daylengths. The ba...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528709078520
更新日期:1987-01-01 00:00:00
abstract::The avian circadian system is composed of the retina, the mammalian homolog region of the suprachiasmatic nucleus (SNC), and the pineal gland. The retina, itself, displays many rhythmic physiological events, such as movements of photoreceptor cells, opsin expression, retinal reisomerization, and melatonin and dopamine...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.3109/07420528.2010.540685
更新日期:2011-03-01 00:00:00
abstract::Although there are significant intra-individual differences in self-reported diurnal preference, as measured by validated questionnaires, the relative contribution of exogenous and endogenous factors to self-reported diurnal preference largely remains to be investigated. The present study examined which items from the...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520902820970
更新日期:2009-04-01 00:00:00
abstract::Sleep and fatigue-associated symptoms are prominent during chemotherapy. The purpose of this pilot study was to examine bright light effects on sleep disruption, fatigue, daytime sleepiness, depression, and quality of life (QOL) in women with stage I-III breast cancer undergoing chemotherapy. In this 2-group randomize...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420528.2021.1871914
更新日期:2021-01-21 00:00:00
abstract::Night shiftworkers often complain of disturbed sleep during the day. This could be partly caused by morning sunlight exposure during the commute home, which tends to maintain the circadian clock on a daytime rhythm. The circadian clock is most sensitive to the blue portion of the visible spectrum, so our aim was to de...
journal_title:Chronobiology international
pub_type: 杂志文章
doi:10.1080/07420520903044398
更新日期:2009-07-01 00:00:00