Abstract:
:The advent of new laboratory methods and noninvasive imaging modalities has extended the diagnostic possibilities in normal individuals. This article elaborates the new options for the assessment of stroke risk offered by these techniques. In this context we present the Austrian Stroke Prevention Study, which is the first prospective long-term investigation of normals that includes Doppler sonography, magnetic resonance imaging and single photon emission computed tomography. The design, utility and limitations of this study are discussed.
journal_name
Neuroepidemiologyjournal_title
Neuroepidemiologyauthors
Schmidt R,Lechner H,Fazekas F,Niederkorn K,Reinhart B,Grieshofer P,Horner S,Offenbacher H,Koch M,Eber Bdoi
10.1159/000110396subject
Has Abstract,Author List Incompletepub_date
1994-01-01 00:00:00pages
308-13issue
6eissn
0251-5350issn
1423-0208journal_volume
13pub_type
杂志文章abstract:AIMS:In order to examine the hypothesis that elevated resting heart rate (RHR) is associated with impaired cognitive score, we investigated the relationship between RHR and cognitive score in middle-aged, elderly and old Danish subjects from the general population. METHODS:Composite cognitive scores derived from the r...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000487802
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Parkinson's disease (PD) is the most common neurodegenerative disease after Alzheimer's dementia. Whereas the exact etiology of PD remains unknown, risk of developing PD seems to be related to a combination of genetic and environmental factors. This also includes abnormal exposure to trace elements of nutrit...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000502357
更新日期:2020-01-01 00:00:00
abstract::We tested the feasibility of a fully automated brain MRI voxel count technique--automated labeling pathway (ALP)--in a sample of 15 demented and 13 cognitively normal women (age 75-85 years) participating to the Cardiovascular Health Study (CHS). We hypothesized that ALP would replicate well-established findings of th...
journal_title:Neuroepidemiology
pub_type: 临床试验,杂志文章
doi:10.1159/000085140
更新日期:2005-01-01 00:00:00
abstract::Many Parkinson's disease (PD) patients treated with levodopa develop motor fluctuations and/or dyskinesia. This large, retrospective study was conducted to compare the prevalence and treatment of dyskinesia in PD patients in seven countries. A total of 380 physicians were interviewed and completed patient record forms...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000111578
更新日期:2007-01-01 00:00:00
abstract::A pilot case-control study was conducted to identify possible risk factors for Meige's syndrome. Patients with Meige's syndrome and age- and sex-matched controls suffering from other neurological diseases were recruited from the Movement Disorders Clinic and Neurology Outpatient Department of the All India Insititute ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026265
更新日期:2000-09-01 00:00:00
abstract::The epidemiology of multiple sclerosis (MS) in Austria is almost unknown. We evaluated the prevalence of MS in Austria using data from questionnaires completed by neurologists, comprising information on a total of 1,006 MS patients who attended 30 out-patient specialized clinics nationwide. Additional data were collec...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000065640
更新日期:2002-09-01 00:00:00
abstract::In the past several years, a substantial amount of new information on the epidemiology and pathophysiology of diabetes and vascular disease has become available. Autopsy studies suggest that diabetic patients are susceptible to cerebral small-artery disease and lacunar infarction and may be at risk for large-artery at...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
doi:10.1159/000026190
更新日期:1999-01-01 00:00:00
abstract::The epsilon 4 allele of the apolipoprotein E (apoE) is associated with Alzheimer's disease (AD) and also with elevated serum total cholesterol and low-density lipoprotein levels. However, the interrelationships between apoE genotype, plasma cholesterol levels and AD risk have been studied very little. We examined the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026149
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIMS:Neurosarcoidosis is a rare condition with serious health consequences. However, little is known about clinical characteristics and outcome of neurosarcoidosis in the community setting. METHODS:Patients with neurosarcoidosis were identified from a previously described cohort of patients with incident sa...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000477300
更新日期:2017-01-01 00:00:00
abstract::White matter lesions (WML) on MRI of the brain are common in both demented and nondemented older persons. They may be due to ischemic events and are associated with cognitive and physical impairments. It is not known whether the prevalence of these WML in the general population differs across European countries in a p...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000089233
更新日期:2006-01-01 00:00:00
abstract::Several scores exist to clinically differentiate between ischemic and hemorrhagic stroke, but none has been developed in the emergency situation in which transient ischemic attack (TIA) and cerebral infarction might not yet be clearly distinguished. Information on 540 patients with ischemia (including TIA) or hemorrha...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000048608
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Short-term exposure to high levels of air pollution can increase stroke risk. In this study we investigated the short-term effects of air pollution on hospital admissions for stroke in a setting where pollutant levels are rather low. We also addressed methodological issues in evaluating the short-term effect...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000274807
更新日期:2010-01-01 00:00:00
abstract::Some dementias, such as Creutzfeldt-Jakob disease, may result from transmissible agents. To assess the possibility of a blood-borne transmissible agent in Alzheimer's disease (AD), we compared informant-reported history of blood transfusions among 326 newly recognized probable AD cases and 330 control subjects of simi...
journal_title:Neuroepidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000109675
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Incidence and prevalence studies of neurological disorders play an extremely important role in hypothesis-generation, assessing the burden of disease and planning of health services. However, the assessment of disease estimates is hindered by the poor quality of reporting for such studies. We developed the S...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000439132
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:The excess stroke mortality among African Americans and Southerners is well known. Because a higher proportion of the population living in the 'Stroke Belt' is African American, then a portion of the estimated excess risk of stroke death traditionally associated with African-American race may be attributab...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000075954
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Hereditary ataxias (HA) comprise a group of genetically heterogeneous rare diseases. As important public health problems to be monitored, this study analyses the morbimortality of HA in Spain. METHODS:Data were extracted from the national death index (1981-2008), using the International Classification of Di...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000346275
更新日期:2013-01-01 00:00:00
abstract::The aim of the study was to evaluate how the natural history of multiple sclerosis (MS) had changed over a 15-year period. We compared disability and mortality in a cohort of 83 MS patients hospitalised in the Neurological Institute of Pavia, northern Italy, from January 1, 1990, to December 31, 1991, with a similar c...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000085308
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Studies on dyskinesia and Parkinson's syndrome associated with chronic kidney disease or end-stage renal disease (ESRD) have been mainly limited to case reports or case series studies. This population-based study investigated the risk of Parkinson's disease in patients with ESRD. METHODS:From a universal in...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000358921
更新日期:2014-01-01 00:00:00
abstract::From July 1988 to June 1989, the etiology was registered of 520 patients with generalized neuropathy in 5 neurological centers in Taiwan. The neuropathy was diabetic in 256 cases (49.23%), alcoholic in 45 (8.65%), inflammatory in 34 (6.53%; including 21 with acute inflammatory demyelinating polyneuropathy, 12 with chr...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000110326
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Despite decades of research, there are no national estimates of the incidence or prevalence of spinal cord injury (SCI) in Canada. Our objective was to utilize the best available data to estimate the incidence and prevalence of traumatic SCI (TSCI) and non-traumatic SCI (NTSCI) in Canada for 2010. METHODS:I...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000336014
更新日期:2012-01-01 00:00:00
abstract::The multiple sclerosis (MS) prevalence rates in five districts of Bulgaria were compared with some geographic and climatic factors. In Bulgaria the latitude seems not to be a factor influencing the MS distribution. As to the climatic factors, a negative correlation was obtained between MS prevalence and mean annual su...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110106
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND/AIMS:Cognitive decline is a defining feature of dementia. We sought to determine if a single baseline cognitive test score or change in test score over time is more strongly associated with risk of dementia hospitalization. We also sought to compare short- and long-term dementia risk. METHODS:Prospective co...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000342308
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:White matter hyperintensities (WMHs) are a risk factor for stroke. Their etiology is considered to be cerebral microvascular abnormality. However, the association between WMHs and arteriosclerosis is not yet clear. The aim of this hospital-based cohort study was to identify the arteriosclerotic characteristi...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000328260
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Lifespan is 6-10 years shorter in multiple sclerosis (MS), but the reasons remain unclear. Using linked clinical- and population-based administrative health databases, we compared cause-specific mortality in an MS cohort to the general population. METHODS:MS patients in British Columbia (BC), Canada, were f...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000504804
更新日期:2020-01-01 00:00:00
abstract::We consider the problem of testing that a disease with variable age at onset is an autosomal dominant or recessive genetic trait. Specific reference is made to Alzheimer's disease and recent publications proposing an autosomal dominant inheritance pattern. The pedigree structure allowed is restricted to first-degree r...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110139
更新日期:1988-01-01 00:00:00
abstract::Recent reports of declining trends in mortality rates from cerebrovascular disease are based on underlying cause of death as stated on the death certificate, and may contain inaccuracies because death certificates are often completed without reference to all information in medical records, and because of changes in co...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110160
更新日期:1989-01-01 00:00:00
abstract::The incidence rate for primary intracranial neoplasms in the province of Trento (Italy) is 8.5/100,000/year, but the figures in the eleven administrative units ('comprensori') are different. The increased rates in C6 Val di Non and C10 Vallagarina are mainly due to the number of malignant tumors in the 45- to 64-year-...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110825
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:No epidemiological studies on the prevalence of compressive neuropathy have been undertaken in Arab countries. The aim of the study was to estimate the prevalence of the most common types of compressive neuropathies in Qena governorate/Egypt. METHODS:The study was part of a community-based survey carried ou...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000444641
更新日期:2016-01-01 00:00:00
abstract::A random sample of nursing home residents over 65 years of age were interviewed. Two hundred ninety-two participants received the Short Portable Mental Status Questionnaire. Two hundred eleven were unable to answer the questionnaire, but their caregivers provided information about their daily activities and performanc...
journal_title:Neuroepidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000026166
更新日期:1998-01-01 00:00:00
abstract::In this report we describe the establishment of a Neuro-Oncology Register (NOR) at the University Hospital of Maastricht, The Netherlands. The register includes data on numbers and types of primary central nervous system (CNS) tumours and neurological complications of systemic cancer. One of the objectives of the regi...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110939
更新日期:1992-01-01 00:00:00