Pitfalls in neuroepidemiologic research.

abstract：:The epsilon 4 allele of the apolipoprotein E (apoE) is associated with Alzheimer's disease (AD) and also with elevated serum total cholesterol and low-density lipoprotein levels. However, the interrelationships between apoE genotype, plasma cholesterol levels and AD risk have been studied very little. We examined the ...

journal_title：Neuroepidemiology

authors： Notkola IL,Sulkava R,Pekkanen J,Erkinjuntti T,Ehnholm C,Kivinen P,Tuomilehto J,Nissinen A

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The effects of oophorectomy on brain aging remain uncertain. METHODS:We conducted a cohort study with long-term follow-up of women in Olmsted County, Minn., USA, who underwent either unilateral or bilateral oophorectomy before the onset of menopause from 1950 through 1987. Each member of the oophorectomy co...

journal_title：Neuroepidemiology

authors： Rivera CM,Grossardt BR,Rhodes DJ,Rocca WA

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Hereditary cerebellar ataxias (HCA) and hereditary spastic paraplegias (HSP) are two groups of neurodegenerative disorders that usually present with progressive gait impairment, often leading to permanent disability. Advances in genetic research in the last decades have improved their diagnosis and brought n...

journal_title：Neuroepidemiology

authors： Ruano L,Melo C,Silva MC,Coutinho P

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:We assessed the association between pre-stroke cognitive status and 90-day case-fatality. METHODS:Patients with ischemic stroke (IS) or spontaneous intracerebral hemorrhage (ICH) were prospectively identified among residents of Dijon, France, between 2013 and 2015, using a population-based registry. Associat...

journal_title：Neuroepidemiology

authors： Graber M,Garnier L,Mohr S,Delpont B,Blanc-Labarre C,Vergely C,Giroud M,Béjot Y

更新日期：2020-01-01 00:00:00

abstract：:Several scores exist to clinically differentiate between ischemic and hemorrhagic stroke, but none has been developed in the emergency situation in which transient ischemic attack (TIA) and cerebral infarction might not yet be clearly distinguished. Information on 540 patients with ischemia (including TIA) or hemorrha...

journal_title：Neuroepidemiology

authors： Stürmer T,Schlindwein G,Kleiser B,Roempp A,Brenner H

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Recent interest in antihypertensive agents, especially calcium channel blockers, has been sparked by the notion that these medications may be neuroprotective. A modest literature, with mixed results, has examined whether these medications might lower the odds or risk of Parkinson's disease (PD) or dementia. ...

journal_title：Neuroepidemiology

authors： Louis ED,Benito-León J,Bermejo-Pareja F,Neurological Disorders in Central Spain (NEDICES) Study Group.

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between hepatitis B (HB) vaccination and a first central nervous system (CNS) demyelinating event in adults. METHODS:In 1998, we conducted a multicentre, hospital-based case-control study which enrolled 402 cases of first CNS demyelinating event occurring between 1994 and 1995...

journal_title：Neuroepidemiology

authors： Touzé E,Fourrier A,Rue-Fenouche C,Rondé-Oustau V,Jeantaud I,Bégaud B,Alpérovitch A

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To assess the knowledge of stroke in the general public in the Gulf Cooperation Council (GCC) countries. BACKGROUND:The Arabian Gulf is a rapidly developing part of the world with major changes in the lifestyle that can increase the risk of stroke. To design effective stroke treatment and prevention strategi...

journal_title：Neuroepidemiology

authors： Kamran S,Bener AB,Deleu D,Khoja W,Jumma M,Al Shubali A,Inshashi J,Sharouqi I,Al Khabouri J

更新日期：2007-01-01 00:00:00

abstract：:Little is known regarding the pathogenetic factors for Alzheimer's disease (AD). We studied 63 AD patients in order to evaluate if there were clinical subtypes of AD and whether prior illnesses and life-styles were involved in the development of the disease. In our patients selected for onset of symptoms before age 65...

journal_title：Neuroepidemiology

authors： Ferini-Strambi L,Smirne S,Garancini P,Pinto P,Franceschi M

更新日期：1990-01-01 00:00:00

abstract：:In the past several years, a substantial amount of new information on the epidemiology and pathophysiology of diabetes and vascular disease has become available. Autopsy studies suggest that diabetic patients are susceptible to cerebral small-artery disease and lacunar infarction and may be at risk for large-artery at...

journal_title：Neuroepidemiology

authors： Lukovits TG,Mazzone TM,Gorelick TM

更新日期：1999-01-01 00:00:00

abstract：:The advent of new laboratory methods and noninvasive imaging modalities has extended the diagnostic possibilities in normal individuals. This article elaborates the new options for the assessment of stroke risk offered by these techniques. In this context we present the Austrian Stroke Prevention Study, which is the f...

journal_title：Neuroepidemiology

authors： Schmidt R,Lechner H,Fazekas F,Niederkorn K,Reinhart B,Grieshofer P,Horner S,Offenbacher H,Koch M,Eber B

更新日期：1994-01-01 00:00:00

abstract：:White matter lesions (WMLs) detected by cerebral magnetic resonance imaging (MRI) are putatively a consequence of cerebral hypoperfusion or ischemia. We investigated the prevalence, severity and correlates of WMLs in a population-based sample of 1,920 African-American and European-American men and women aged 55-72 yea...

journal_title：Neuroepidemiology

authors： Liao D,Cooper L,Cai J,Toole J,Bryan N,Burke G,Shahar E,Nieto J,Mosley T,Heiss G

更新日期：1997-01-01 00:00:00

abstract：:A total of 186 cases of motor neuron disease (MND) was identified in two Danish counties during the period 1974-1986. The average annual incidence rate was 1.4/100,000 population, and the male:female ratio of incidence rates was 1.5. Mean age at diagnosis was 64.3 +/- 10.0 years. The incidence rates increased signific...

journal_title：Neuroepidemiology

authors： Højer-Pedersen E,Christensen PB,Jensen NB

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:We examined the prevalence of cardiac and cerebrovascular disease among hospitalized patients with and without multiple sclerosis (MS). METHODS:This study used the Statewide Planning and Research Cooperate System data set of over 15 million hospitalizations in New York City from 1988 through 2002. We identi...

journal_title：Neuroepidemiology

authors： Allen NB,Lichtman JH,Cohen HW,Fang J,Brass LM,Alderman MH

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Brain tumours (BT) are one of the most frequent tumour types in young people, although little is known about their risk factors. OBJECTIVE:The objective of the current work was to review and summarize the scientific literature concerning exposure to environmental factors and BT risk in young people (<25 yea...

journal_title：Neuroepidemiology

authors： Zumel-Marne A,Castano-Vinyals G,Kundi M,Alguacil J,Cardis E

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Limited epidemiological data exist about amyotrophic lateral sclerosis (ALS) in the United States (US). The Agency for Toxic Substances and Disease Registry maintains the National ALS Registry and funded state and metropolitan surveillance projects to obtain reliable, timely information about ALS in defined ...

journal_title：Neuroepidemiology

authors： Jordan H,Fagliano J,Rechtman L,Lefkowitz D,Kaye W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Studies on dyskinesia and Parkinson's syndrome associated with chronic kidney disease or end-stage renal disease (ESRD) have been mainly limited to case reports or case series studies. This population-based study investigated the risk of Parkinson's disease in patients with ESRD. METHODS:From a universal in...

journal_title：Neuroepidemiology

authors： Wang IK,Lin CL,Wu YY,Chou CY,Lin SY,Liu JH,Yen TH,Huang CC,Sung FC

更新日期：2014-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic and progressively disabling inflammatory autoimmune disorder of the central nervous system. MS has a multifactorial etiology and is triggered by environmental factors in individuals with complex genetic risk profiles. The epidemiology of MS changes with the spatial and temporal dis...

journal_title：Neuroepidemiology

authors： Al-Afasy HH,Al-Obaidan MA,Al-Ansari YA,Al-Yatama SA,Al-Rukaibi MS,Makki NI,Suresh A,Akhtar S

更新日期：2013-01-01 00:00:00

abstract：:According to studies done before 1980, the multiple sclerosis (MS) prevalence rate in Italy ranged from 7.2 to 27.1 cases per 100,000 inhabitants. More recent work has consistently put the MS prevalence rate to over 30 cases per 100,000 inhabitants. If these recent data are confirmed in the future, Italy can no longer...

journal_title：Neuroepidemiology

authors： Sironi L,Mamoli A,D'Alessandro G,Camerlingo M,Bottacchi E

更新日期：1991-01-01 00:00:00

abstract：:The recognition that cognitive impairment of vascular origin is not limited to multi-infarct dementia has led to the development of several sets of new criteria for vascular dementia (VaD). We set out to define the spectrum of disease in patients presenting with vascular cognitive impairment (VCI). Of 412 patients con...

journal_title：Neuroepidemiology

authors： Rockwood K,Howard K,MacKnight C,Darvesh S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Higher education is associated with a lower risk of dementia, possibly because of a higher tolerance to subclinical neurodegenerative pathology. Whether higher education also protects against dementia after clinical stroke or transient ischemic attack (TIA) remains unknown. METHODS:Within the population-bas...

journal_title：Neuroepidemiology

authors： Mirza SS,Portegies ML,Wolters FJ,Hofman A,Koudstaal PJ,Tiemeier H,Ikram MA

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Familial aggregation has been shown for Alzheimer's disease (AD) and Parkinson's disease (PD) separately, and it has been hypothesized that these diseases also coaggregate in families. METHODS:The authors investigated familial coaggregation of AD and PD by conducting a systematic review and meta-analysis. P...

journal_title：Neuroepidemiology

authors： Feldman AL,Johansson AL,Lambert PC,Sieurin J,Yang F,Pedersen NL,Wirdefeldt K

更新日期：2014-01-01 00:00:00

abstract：:Homocysteine is a metabolite of methionine that may be remethylated by enzymes requiring folate and cobalamin (vitamin B12) to again form methionine or catabolized by the pyridoxine (vitamin B6) dependent enzyme, cystathionine beta synthase (CBS) to form cysteine (fig. 1) [1]. Homocysteine exists as a combination of v...

journal_title：Neuroepidemiology

authors： Sacco RL,Roberts JK,Jacobs BS

更新日期：1998-01-01 00:00:00

abstract：:216 survivors of acute stroke were studied 3 months postictus to determine predictors of long-term survival and disability 20 months after the initial stroke. Factors predicting mortality were, in order of importance, old age, a history of ischaemic heart disease, low mental-test score, low serum cholesterol concentra...

journal_title：Neuroepidemiology

authors： Woo J,Kay R,Yuen YK,Nicholls MG

更新日期：1992-01-01 00:00:00

abstract：:We report anticipation in an extensive sample of myotonic dystrophy (MyD) kindreds taken from an epidemiological survey recently conducted in Guipúzcoa, Spain. Analysis of the parent-child pairs ascertained showed a mean anticipation of 2.86 decades (range 0-6). Greater anticipation occurred when the transmissor paren...

journal_title：Neuroepidemiology

authors： López de Munain A,Blanco A,Emparanza JI,Martí Massó JF,Cobo A,Basauri B,Martorell L,Baiget M,Martínez Lage JM

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Genetic association studies conducted in admixed populations may be confounded by population stratification resulting in spurious associations. The purpose of this pilot study was to determine the presence and effect of population stratification in a case-control study of brain arteriovenous malformation (BA...

journal_title：Neuroepidemiology

authors： Kim H,Hysi PG,Pawlikowska L,Choudhry S,González Burchard E,Kwok PY,Sidney S,McCulloch CE,Young WL

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Transversal studies have underlined the association between the decline in autonomic nervous system (ANS) activity and all-cause mortality. However, the predictive value of ANS has never been prospectively assessed in a general population-based cohort. METHOD:The PROOF (PROgnostic indicator OF cardiovascula...

journal_title：Neuroepidemiology

authors： Barthélémy JC,Pichot V,Dauphinot V,Celle S,Laurent B,Garcin A,Maudoux D,Kerleroux J,Lacour JR,Kossovsky M,Gaspoz JM,Roche F

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Poorer socioeconomic conditions early in life have been linked with memory, attention and learning deficits in adulthood, as well as with specific areas of educational achievement. It remains unclear, however, whether these distal associations are mediated by more current socioeconomic factors. In this study,...

journal_title：Neuroepidemiology

authors： Kobrosly RW,van Wijngaarden E,Galea S,Cory-Slechta DA,Love T,Hong C,Shamlaye CF,Davidson PW

更新日期：2011-01-01 00:00:00

abstract：:White matter lesions (WML) on MRI of the brain are common in both demented and nondemented older persons. They may be due to ischemic events and are associated with cognitive and physical impairments. It is not known whether the prevalence of these WML in the general population differs across European countries in a p...

journal_title：Neuroepidemiology

authors： Launer LJ,Berger K,Breteler MM,Dufouil C,Fuhrer R,Giampaoli S,Nilsson LG,Pajak A,de Ridder M,van Dijk EJ,Sans S,Schmidt R,Hofman A

更新日期：2006-01-01 00:00:00

abstract：:The incidence rate for primary intracranial neoplasms in the province of Trento (Italy) is 8.5/100,000/year, but the figures in the eleven administrative units ('comprensori') are different. The increased rates in C6 Val di Non and C10 Vallagarina are mainly due to the number of malignant tumors in the 45- to 64-year-...

journal_title：Neuroepidemiology

authors： Ferrari G,Lovaste MG

更新日期：1986-01-01 00:00:00