Abstract:
:Using a case-control method, we studied the role of environmental risk factors and viral infection in the development of Parkinson's disease (PD) in China. Ninety-three PD patients and 186 controls were investigated with a questionnaire and from most of them, blood was taken to test the antibody levels of four virus (measles, rubella, HSV-1, CMV) IgG. The study result showed that positive family history, living near rubber plants, drinking river-water were associated with an increased risk of developing PD. In contrast, living in small cities, drinking well-water, drinking hard-liquor frequently, were associated with a decreased risk for PD. PD cases and controls did not differ with respect to other factors investigated including smoking and viral infection. These findings suggest that some environmental factors may be related to the development of PD, but further standardized studies will be required to confirm our results.
journal_name
Neuroepidemiologyjournal_title
Neuroepidemiologyauthors
Wang WZ,Fang XH,Cheng XM,Jiang DH,Lin ZJdoi
10.1159/000110319subject
Has Abstractpub_date
1993-01-01 00:00:00pages
209-18issue
4eissn
0251-5350issn
1423-0208journal_volume
12pub_type
杂志文章abstract:BACKGROUND:Recent interest in antihypertensive agents, especially calcium channel blockers, has been sparked by the notion that these medications may be neuroprotective. A modest literature, with mixed results, has examined whether these medications might lower the odds or risk of Parkinson's disease (PD) or dementia. ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000235641
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Providing a valid and sensitive measure of different domains of cognitive performance in epidemiologic studies of early old-age populations presents a methodological challenge, given the broad range of variability in cognitive functioning in this age group. OBJECTIVES:(1) To provide data on the distribution...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000328262
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The 'Ten Questions' Questionnaire (TQQ) is used to detect severe neurological impairment in children living in resource-poor countries. Its usefulness has been established in Asia and the Caribbean, but there are a few published studies from Africa. We evaluated the TQQ as part of a larger study of neurologi...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000073977
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Guillain-Barré syndrome (GBS) is a potentially life-threatening disease that typically occurs after a preceding infectious disease. An accurate estimation of GBS incidence would be useful for investigating the potential causal relationships between risk factors and GBS. Here we described the nationwide incid...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000430917
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND AND AIMS:The impact of statin on dementia risk reduction has been a subject of debate over the last decade, but the evidence remains inconclusive. Therefore, we performed a meta-analysis of relevant observational studies to quantify the magnitude of the association between statin therapy and the risk of deme...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000503105
更新日期:2020-01-01 00:00:00
abstract::White matter lesions (WMLs) detected by cerebral magnetic resonance imaging (MRI) are putatively a consequence of cerebral hypoperfusion or ischemia. We investigated the prevalence, severity and correlates of WMLs in a population-based sample of 1,920 African-American and European-American men and women aged 55-72 yea...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000368814
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND AND METHODS:The high prevalence of epilepsy detected in rural Tanzania by Dr. Jilek-Aall since 1960, was verified by the World Health Organization (WHO) survey on neurological and seizure disorders. Neurologists and psychiatrists further interviewed both patients and controls using standard methods. The pres...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000054797
更新日期:2001-10-01 00:00:00
abstract::Little is known regarding the pathogenetic factors for Alzheimer's disease (AD). We studied 63 AD patients in order to evaluate if there were clinical subtypes of AD and whether prior illnesses and life-styles were involved in the development of the disease. In our patients selected for onset of symptoms before age 65...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110750
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:While some personality traits may reduce risk of dementia, this is controversial and has not been studied as much among diverse populations. We examined associations between 2 traits - Conscientiousness and Openness to Experience - and risk of dementia among black and white older adults. METHODS:We studied ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000492821
更新日期:2019-01-01 00:00:00
abstract::Previously, we studied the effect of population ancestry on the risk of multiple sclerosis (MS) in US veterans of World War II, comparing by state 1980 US census ancestry data with MS case/control ratios. Here, the joint effects of population ancestry and surname-derived ethnicity on MS risk are examined in the same s...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109804
更新日期:1995-01-01 00:00:00
abstract::In 1994 several European studies will have available risk factor information on incident cases of dementia collected in prospective community-based studies. These centers will collaborate in a nested-case control study based on the pooled cases and a sample of the non-diseased respondents. This paper describes the gen...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000111005
更新日期:1992-01-01 00:00:00
abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is a rare, rapidly progressive neurodegenerative disease. Despite wide variability in the incidence and prevalence of ALS, there is evidence of positive temporal trends and an increase in incidence with age. The aim of this study was to conduct a detailed epidemiological...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000477126
更新日期:2017-01-01 00:00:00
abstract::We carried out a door-to-door survey in rural areas of the Cordillera Province, Bolivia, to determine the prevalence of the most common neurological diseases in a sample of about 10,000 inhabitants. A team of non-doctor health workers administered a standard screening instrument for neurological diseases, a slightly m...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000048624
更新日期:2002-03-01 00:00:00
abstract::From July 1988 to June 1989, the etiology was registered of 520 patients with generalized neuropathy in 5 neurological centers in Taiwan. The neuropathy was diabetic in 256 cases (49.23%), alcoholic in 45 (8.65%), inflammatory in 34 (6.53%; including 21 with acute inflammatory demyelinating polyneuropathy, 12 with chr...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000110326
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Charcot-Marie-Tooth disease (CMT) is a group of clinically and genetically heterogeneous disorders that primarily affect the peripheral nervous system. Epidemiological studies of CMT have not yet been performed in Korea. OBJECTIVES:This study was performed to estimate the prevalence of CMT in Korea and the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000505815
更新日期:2020-01-01 00:00:00
abstract::In a cooperative study in The Netherlands 22 patients with lissencephaly type I were collected. In the period 1980-1988, the prevalence of lissencephaly type I in the Netherlands was 11.7 per million births (12.2 for females and 11.0 for males). The 5-year survival rate of patients with a complete or nearly complete a...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110270
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The effects of oophorectomy on brain aging remain uncertain. METHODS:We conducted a cohort study with long-term follow-up of women in Olmsted County, Minn., USA, who underwent either unilateral or bilateral oophorectomy before the onset of menopause from 1950 through 1987. Each member of the oophorectomy co...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000211951
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:We explored the association between ionizing radiation (IR) from pre-natal and post-natal radio-diagnostic procedures and brain cancer risk within the MOBI-kids study. METHODS:MOBI-kids is an international (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, New Zealand,...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000506131
更新日期:2020-01-01 00:00:00
abstract:AIM:We examined trends in incidence of stroke of any nature (ischemic and/or hemorrhagic) in subjects with a hospital diagnosis of nonvalvular atrial fibrillation or flutter in Denmark from 1980 to 2002 by sex, age and conditions of comorbidity. METHODS:We identified all individuals, aged 40-89 years, with an incident...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000092795
更新日期:2006-01-01 00:00:00
abstract::The epidemiology of multiple sclerosis (MS) in Austria is almost unknown. We evaluated the prevalence of MS in Austria using data from questionnaires completed by neurologists, comprising information on a total of 1,006 MS patients who attended 30 out-patient specialized clinics nationwide. Additional data were collec...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000065640
更新日期:2002-09-01 00:00:00
abstract::In the past several years, a substantial amount of new information on the epidemiology and pathophysiology of diabetes and vascular disease has become available. Autopsy studies suggest that diabetic patients are susceptible to cerebral small-artery disease and lacunar infarction and may be at risk for large-artery at...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
doi:10.1159/000026190
更新日期:1999-01-01 00:00:00
abstract::This study is based on 166 patients with definite multiple sclerosis (MS) residing in different Italian regions and on 332 parents and 326 siblings. Seven patients had a first-degree relative with a definite diagnosis. The comparison with a population age-matched for specific frequency of MS showed an increase of the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110198
更新日期:1989-01-01 00:00:00
abstract::A pilot case-control study was conducted to identify possible risk factors for Meige's syndrome. Patients with Meige's syndrome and age- and sex-matched controls suffering from other neurological diseases were recruited from the Movement Disorders Clinic and Neurology Outpatient Department of the All India Insititute ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026265
更新日期:2000-09-01 00:00:00
abstract::We investigated the relationship between animal product consumption and evidence of dementia in two cohort substudies. The first enrolled 272 California residents matched for age, sex, and zip code (1 vegan, 1 lacto-ovo-vegetarian, and 2 'heavy' meat eaters in each of 68 quartets). This design ensured a wide range of ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110296
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND/AIMS:The prevalence of epilepsy in Algeria is unknown. The aims of this multicenter transversal study were to determine the national prevalence and clinical characteristics of epilepsy in the Algerian population. METHODS:This two-phase study was conducted in 5 circumscriptions and included 8,046 subjects ag...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000339637
更新日期:2012-01-01 00:00:00
abstract::A comparison of epidemiological and clinical features of trigeminal neuralgia (TN) and glossopharyngeal neuralgia (GN) in Rochester, Minn., reveals several differences. The overall age- and sex-adjusted annual incidence rates were significantly higher for TN than for GN (4.7 vs. 0.8 per 100,000 population). The TN:GN ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110284
更新日期:1991-01-01 00:00:00
abstract::Since the middle of this century, a remarkable concentration of cases of neurodegenerative disease(s), referred to as amyotrophic lateral sclerosis and Parkinson-dementia complex (ALS/PDC), has been recognized among Chamorro natives of Guam. Intense investigations over the last 4 decades have failed to determine the e...
journal_title:Neuroepidemiology
pub_type: 历史文章,杂志文章,评审
doi:10.1159/000026223
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Parkinson's disease (PD) is the most common neurodegenerative disease after Alzheimer's dementia. Whereas the exact etiology of PD remains unknown, risk of developing PD seems to be related to a combination of genetic and environmental factors. This also includes abnormal exposure to trace elements of nutrit...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000502357
更新日期:2020-01-01 00:00:00
abstract::An increased risk for first-degree relatives (FDR) of glioma patients has previously been observed. The novel objective of this study was to investigate differences in familial risk among FDR of low-grade glioma (LGG) and high-grade glioma (HGG) cases, respectively. Two cohorts were constructed, one from 15,321 FDR of...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000065528
更新日期:2002-11-01 00:00:00
abstract::The purpose of our study was to determine the incidence of stroke, case-fatality rate and disability at 1 year in the Valley of Aosta (Italy) in the years 2004 and 2005. All suspected strokes occurring between January 1, 2004, and December 31, 2005, in the resident population of the Valley of Aosta were identified acc...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000195688
更新日期:2009-01-01 00:00:00