Abstract:
AIM:We examined trends in incidence of stroke of any nature (ischemic and/or hemorrhagic) in subjects with a hospital diagnosis of nonvalvular atrial fibrillation or flutter in Denmark from 1980 to 2002 by sex, age and conditions of comorbidity. METHODS:We identified all individuals, aged 40-89 years, with an incident hospital diagnosis of atrial fibrillation or flutter and no history of stroke or heart valve disease in the Danish National Registry of Patients, and subjects were followed in the Danish National Registry of Patients for occurrence of an incident diagnosis of stroke of any nature (ischemic and/or hemorrhagic) and in the Danish Civil Registration System (emigration and vital status). We used multivariate Cox proportional hazard regression analysis to estimate trends in incidence of stroke. RESULTS:Nonvalvular atrial fibrillation or flutter was diagnosed in 141,493 subjects (75,126 men and 66,367 women), and during follow-up 15,964 subjects had an incident diagnosis of stroke. The hazard ratios for stroke in the last 3-year period compared to the first 5-year period, adjusted for 10-year age group, conditions of comorbidity, and general stroke trend in the Danish population were 0.78 (95% CI 0.70-0.86) in men, and 0.80 (95% CI 0.72-0.88) in women. The reduction in risk of stroke by calendar year was most prominent in patients aged 40-74 years. CONCLUSION:We observed a modest decrease in risk of stroke in subject with atrial fibrillation in Denmark during calendar years 1980-2002. However, we could not control for any changes in diagnostic performance, admission practice, and medical management of patients with atrial fibrillation.
journal_name
Neuroepidemiologyjournal_title
Neuroepidemiologyauthors
Frost L,Vukelic Andersen L,Vestergaard P,Husted S,Mortensen LSdoi
10.1159/000092795subject
Has Abstractpub_date
2006-01-01 00:00:00pages
212-9issue
4eissn
0251-5350issn
1423-0208pii
92795journal_volume
26pub_type
杂志文章abstract:BACKGROUND AND PURPOSE:There is increasing evidence that the pathophysiologic mechanisms are different between migraine and tension-type headache. The aim of the study was to determine possible sociodemographic differences in Saudi Arabia subjects with headache. METHODOLOGY:A community-based door-to-door survey with i...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109670
更新日期:1997-01-01 00:00:00
abstract::A strategy for assessing the clinical importance of statistically significant treatment benefits in recent dementia drug trials is proposed. Traditional criteria for the assessment of valid inferences are helpful: the more likely the treatment effects are valid, the greater the chance that they will be clinically impo...
journal_title:Neuroepidemiology
pub_type: 杂志文章
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更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Limited epidemiological data exist about amyotrophic lateral sclerosis (ALS) in the United States (US). The Agency for Toxic Substances and Disease Registry maintains the National ALS Registry and funded state and metropolitan surveillance projects to obtain reliable, timely information about ALS in defined ...
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pub_type: 杂志文章
doi:10.1159/000365850
更新日期:2014-01-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110198
更新日期:1989-01-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2005-01-01 00:00:00
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更新日期:2004-07-01 00:00:00
abstract::An epidemiological study was performed with respect to Creutzfeldt-Jakob disease in a designated area in Japan. The subjects were observed in a small rural prefecture where the population generally remains within a limited radius throughout their lives. The patients' life-styles in each area were investigated in detai...
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1997-01-01 00:00:00
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更新日期:2001-10-01 00:00:00
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pub_type: 杂志文章,meta分析
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更新日期:2019-01-01 00:00:00
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更新日期:2010-01-01 00:00:00
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更新日期:2005-01-01 00:00:00
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更新日期:2008-01-01 00:00:00
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更新日期:1990-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-01-01 00:00:00
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更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2012-01-01 00:00:00
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更新日期:2012-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1989-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-05-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000235641
更新日期:2009-01-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000059520
更新日期:2002-07-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
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更新日期:1993-01-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Neuroepidemiology
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00