Case-control study of Meige's syndrome. Result of a pilot study.


:A pilot case-control study was conducted to identify possible risk factors for Meige's syndrome. Patients with Meige's syndrome and age- and sex-matched controls suffering from other neurological diseases were recruited from the Movement Disorders Clinic and Neurology Outpatient Department of the All India Insititute of Medical Sciences. All participants were interviewed and information regarding psychiatric and medical illnesses, use of medications, exposure to fumes, dust and pets, characteristics such as marital status, socio-economic status, alcohol, tea/coffee use, tobacco use, betel nut chewing and family history of neurodegenerative diseases among first-degree relatives was ascertained. We found that betel nut with tobacco chewing was a significant predictor for Meige's syndrome (adjusted odds ratio 7.4, 95% confidence interval = 1.0-59. 82). The role of local irritation or the effect of some chemicals in tobacco and betel nuts needs further evaluation of the pathogenesis of Meige's syndrome.






Behari M,Sharma AK,Changkakoti S,Sharma N,Pandey RM




Has Abstract


2000-09-01 00:00:00














  • Assessing the clinical importance of statistically significant improvement in anti-dementia drug trials.

    abstract::A strategy for assessing the clinical importance of statistically significant treatment benefits in recent dementia drug trials is proposed. Traditional criteria for the assessment of valid inferences are helpful: the more likely the treatment effects are valid, the greater the chance that they will be clinically impo...


    pub_type: 杂志文章


    authors: Rockwood K,MacKnight C

    更新日期:2001-05-01 00:00:00

  • Creation of a bilingual Spanish-English version of the Questionnaire for Verifying Stroke-free Status.

    abstract::Spanish-language versions of standardized questionnaires are important for facilitating inclusion of Hispanic populations in epidemiologic, genetic, and clinical studies. We aimed at producing a culturally adapted Spanish translation of the Questionnaire for Verifying Stroke-free Status (QVSS), an instrument used to s...


    pub_type: 杂志文章


    authors: Castillo PR,Brott TG,Alvarez S,Meschia JF

    更新日期:2004-09-01 00:00:00

  • The prevalence and severity of white matter lesions, their relationship with age, ethnicity, gender, and cardiovascular disease risk factors: the ARIC Study.

    abstract::White matter lesions (WMLs) detected by cerebral magnetic resonance imaging (MRI) are putatively a consequence of cerebral hypoperfusion or ischemia. We investigated the prevalence, severity and correlates of WMLs in a population-based sample of 1,920 African-American and European-American men and women aged 55-72 yea...


    pub_type: 杂志文章


    authors: Liao D,Cooper L,Cai J,Toole J,Bryan N,Burke G,Shahar E,Nieto J,Mosley T,Heiss G

    更新日期:1997-01-01 00:00:00

  • Epidemiology of Amyotrophic Lateral Sclerosis in the Republic of Cyprus: A 25-Year Retrospective Study.

    abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is a rare, rapidly progressive neurodegenerative disease. Despite wide variability in the incidence and prevalence of ALS, there is evidence of positive temporal trends and an increase in incidence with age. The aim of this study was to conduct a detailed epidemiological...


    pub_type: 杂志文章


    authors: Demetriou CA,Hadjivasiliou PM,Kleopa KA,Christou YP,Leonidou E,Kyriakides T,Zamba-Papanicolaou E

    更新日期:2017-01-01 00:00:00

  • On the fine structure of the distribution of primary nervous system neoplasms in Western Poland.

    abstract::The incidence rates of primary nervous system neoplasms in 5 districts (large administrative units) of Western Poland with a relatively homogeneous health care system but some contrasts in economic activity, as well as in 224 communes (smallest administrative units) located within these 5 districts, with a total popul...


    pub_type: 杂志文章


    authors: Wender M,Pruchnik-Grabowska D,Kowal P,Tokarz E

    更新日期:1985-01-01 00:00:00

  • Population-based validation of the iScore for predicting mortality and early functional outcome in ischemic stroke patients.

    abstract:BACKGROUND:We aimed to determine the accuracy of the iScore for predicting mortality and early disability following ischemic stroke in a French population-based study. METHODS:All patients with acute ischemic stroke were identified among residents of the city of Dijon, France, between 2006 and 2011, using a population...


    pub_type: 杂志文章


    authors: Béjot Y,Jacquin A,Daubail B,Durier J,Giroud M

    更新日期:2013-01-01 00:00:00

  • Population-based epidemiological study of neurological diseases in Taiwan: I. Creutzfeldt-Jakob disease and multiple sclerosis.

    abstract:BACKGROUND:The purpose of the study is to investigate the epidemiology of Creutzfeldt-Jakob disease (CJD) and multiple sclerosis (MS) in Taiwan. METHODS:Cases of CJD and MS were identified from the National Health Insurance Research Database from January 2000 to December 2005. Age- and sex-specific incidences of these...


    pub_type: 杂志文章


    authors: Lai CH,Tseng HF

    更新日期:2009-01-01 00:00:00

  • Prevalence of essential tremor: a door-to-door survey in bidasoa, spain.

    abstract:OBJECTIVES:To assess the prevalence of essential tremor (ET) in two Spanish populations (Irun and Hondarribia, Bidasoa region) and to compare the results with those of similar surveys. METHODS:The survey included 2,000 participants aged 65 years or older in a door-to-door, two-phase design. ET was defined as postural ...


    pub_type: 杂志文章


    authors: Bergareche A,De La Puente E,López De Munain A,Sarasqueta C,De Arce A,Poza JJ,Martí-Massó JF

    更新日期:2001-05-01 00:00:00

  • Epidemiologic approach to the study of dementing diseases: a nested case-control study in European incidence studies of dementia.

    abstract::In 1994 several European studies will have available risk factor information on incident cases of dementia collected in prospective community-based studies. These centers will collaborate in a nested-case control study based on the pooled cases and a sample of the non-diseased respondents. This paper describes the gen...


    pub_type: 杂志文章


    authors: Launer LJ,Brayne C,Breteler MM

    更新日期:1992-01-01 00:00:00

  • Stroke in South Asia: a systematic review of epidemiologic literature from 1980 to 2010.

    abstract:BACKGROUND:Globally 15 million people have an acute stroke every year and one third of them die secondary to stroke events. Most research on stroke prevention and treatment is done in developed countries, yet more than 85% of strokes occur in developing countries. In particular, stroke remains an underrecognized cause ...


    pub_type: 杂志文章,评审


    authors: Kulshreshtha A,Anderson LM,Goyal A,Keenan NL

    更新日期:2012-01-01 00:00:00

  • The management approaches to dyskinesia vary from country to country.

    abstract::Many Parkinson's disease (PD) patients treated with levodopa develop motor fluctuations and/or dyskinesia. This large, retrospective study was conducted to compare the prevalence and treatment of dyskinesia in PD patients in seven countries. A total of 380 physicians were interviewed and completed patient record forms...


    pub_type: 杂志文章


    authors: Woitalla D,Mueller T,Russ H,Hock K,Haeger DA

    更新日期:2007-01-01 00:00:00

  • Does Alzheimer's disease protect against cancers? A nationwide population-based study.

    abstract:BACKGROUND:Previous studies suggested a decreased risk of cancer among patients with Alzheimer's disease (AD). There is still a lack of data on the specific types of cancer, the risk factors, and the impact of cholinesterase inhibitors on developing cancer in AD. METHODS:We performed a nationwide population-based stud...


    pub_type: 杂志文章


    authors: Ou SM,Lee YJ,Hu YW,Liu CJ,Chen TJ,Fuh JL,Wang SJ

    更新日期:2013-01-01 00:00:00

  • A population-based prospective 24-month study of stroke: incidence and 30-day case-fatality rates of first-ever strokes in Croatia.

    abstract:BACKGROUND:In Central/Eastern European countries, cerebrovascular diseases are among the leading causes of mortality. We aimed to determine the incidence of first-ever stroke (FES) in the north-western part of Croatia. METHODS:A population-based prospective incidence study was conducted between July 1, 2007, and June ...


    pub_type: 杂志文章


    authors: Pikija S,Cvetko D,Malojčić B,Trkanjec Z,Pavliček I,Lukić A,Kopjar A,Hajduk M,Andrović A,Bilić-Genter M,Trkulja V

    更新日期:2012-01-01 00:00:00

  • High prevalence of mild cognitive impairment in the elderly: a community-based study in four cities of the Hebei province, china.

    abstract:BACKGROUND:Mild cognitive impairment (MCI) has been suggested as a term for a boundary area between normal aging and dementia. This study was designed to determine the prevalence of MCI in the elderly in the Hebei province, China, and explore its related factors. METHODS:Participants included 2,601 community-dwelling ...


    pub_type: 杂志文章


    authors: Xu S,Xie B,Song M,Yu L,Wang L,An C,Zhu Q,Han K,Zhao X,Zhang R,Dong L,Chai N,Gao Y,Zhang Q,Wang X

    更新日期:2014-01-01 00:00:00

  • Hepatitis B vaccination and first central nervous system demyelinating event: a case-control study.

    abstract:OBJECTIVE:To investigate the relationship between hepatitis B (HB) vaccination and a first central nervous system (CNS) demyelinating event in adults. METHODS:In 1998, we conducted a multicentre, hospital-based case-control study which enrolled 402 cases of first CNS demyelinating event occurring between 1994 and 1995...


    pub_type: 杂志文章,多中心研究


    authors: Touzé E,Fourrier A,Rue-Fenouche C,Rondé-Oustau V,Jeantaud I,Bégaud B,Alpérovitch A

    更新日期:2002-07-01 00:00:00

  • Explanation and Elaboration of the Standards of Reporting of Neurological Disorders Checklist: A Guideline for the Reporting of Incidence and Prevalence Studies in Neuroepidemiology.

    abstract:BACKGROUND:Incidence and prevalence studies of neurological disorders play an extremely important role in hypothesis-generation, assessing the burden of disease and planning of health services. However, the assessment of disease estimates is hindered by the poor quality of reporting for such studies. We developed the S...


    pub_type: 杂志文章


    authors: Bennett DA,Brayne C,Feigin VL,Barker-Collo S,Brainin M,Davis D,Gallo V,Jetté N,Karch A,Kurtzke JF,Lavados PM,Logroscino G,Nagel G,Preux PM,Rothwell PM,Svenson LW

    更新日期:2015-01-01 00:00:00

  • Trends in risk of stroke in patients with a hospital diagnosis of nonvalvular atrial fibrillation: National Cohort Study in Denmark, 1980-2002.

    abstract:AIM:We examined trends in incidence of stroke of any nature (ischemic and/or hemorrhagic) in subjects with a hospital diagnosis of nonvalvular atrial fibrillation or flutter in Denmark from 1980 to 2002 by sex, age and conditions of comorbidity. METHODS:We identified all individuals, aged 40-89 years, with an incident...


    pub_type: 杂志文章


    authors: Frost L,Vukelic Andersen L,Vestergaard P,Husted S,Mortensen LS

    更新日期:2006-01-01 00:00:00

  • Spatial Assessment of the Association between Long-Term Exposure to Environmental Factors and the Occurrence of Amyotrophic Lateral Sclerosis in Catalonia, Spain: A Population-Based Nested Case-Control Study.

    abstract:BACKGROUND:It is believed that an interaction between genetic and non-genetic factors may be involved in the development of amyotrophic lateral sclerosis (ALS). With the exception of exposure to agricultural chemicals like pesticides, evidence of an association between environmental risk factors and ALS is inconsistent...


    pub_type: 杂志文章


    authors: Povedano M,Saez M,Martínez-Matos JA,Barceló MA

    更新日期:2018-01-01 00:00:00

  • Incidence of dementia in Melton Mowbray: a proposed study and its problems.

    abstract::This paper describes a proposed study to investigate the incidence of dementia in a population of over 75 year olds in Melton Mowbray, Leicestershire, England. The study population (n = 438) underwent a detailed psychiatric assessment using the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX) as the ...


    pub_type: 杂志文章


    authors: Jagger C,Clarke M,Anderson J

    更新日期:1992-01-01 00:00:00

  • Clinical diagnosis of ischemic versus hemorrhagic stroke: applicability of existing scores in the emergency situation and proposal of a new score.

    abstract::Several scores exist to clinically differentiate between ischemic and hemorrhagic stroke, but none has been developed in the emergency situation in which transient ischemic attack (TIA) and cerebral infarction might not yet be clearly distinguished. Information on 540 patients with ischemia (including TIA) or hemorrha...


    pub_type: 杂志文章


    authors: Stürmer T,Schlindwein G,Kleiser B,Roempp A,Brenner H

    更新日期:2002-01-01 00:00:00

  • Risk factors for multiple sclerosis in Kuwait: a population-based case-control study.

    abstract::Multiple sclerosis (MS) is a chronic and progressively disabling inflammatory autoimmune disorder of the central nervous system. MS has a multifactorial etiology and is triggered by environmental factors in individuals with complex genetic risk profiles. The epidemiology of MS changes with the spatial and temporal dis...


    pub_type: 杂志文章


    authors: Al-Afasy HH,Al-Obaidan MA,Al-Ansari YA,Al-Yatama SA,Al-Rukaibi MS,Makki NI,Suresh A,Akhtar S

    更新日期:2013-01-01 00:00:00

  • Creutzfeldt-Jakob disease in Japan: an epidemiological study done in a select prefecture between 1976 and 1986.

    abstract::An epidemiological study was performed with respect to Creutzfeldt-Jakob disease in a designated area in Japan. The subjects were observed in a small rural prefecture where the population generally remains within a limited radius throughout their lives. The patients' life-styles in each area were investigated in detai...


    pub_type: 杂志文章


    authors: Akai J,Ishihara O,Higuchi S

    更新日期:1989-01-01 00:00:00

  • Cognition and incident dementia hospitalization: results from the atherosclerosis risk in communities study.

    abstract:BACKGROUND/AIMS:Cognitive decline is a defining feature of dementia. We sought to determine if a single baseline cognitive test score or change in test score over time is more strongly associated with risk of dementia hospitalization. We also sought to compare short- and long-term dementia risk. METHODS:Prospective co...


    pub_type: 杂志文章


    authors: Schneider AL,Gottesman RF,Mosley T,Alonso A,Knopman DS,Coresh J,Sharrett AR,Selvin E

    更新日期:2013-01-01 00:00:00

  • Prevalence of Common Types of Compression Neuropathies in Qena Governorate/Egypt: A Population-Based Survey.

    abstract:BACKGROUND:No epidemiological studies on the prevalence of compressive neuropathy have been undertaken in Arab countries. The aim of the study was to estimate the prevalence of the most common types of compressive neuropathies in Qena governorate/Egypt. METHODS:The study was part of a community-based survey carried ou...


    pub_type: 杂志文章


    authors: Khedr EM,Fawi G,Allah Abbas MA,El-Fetoh NA,Zaki AF,Gamea A

    更新日期:2016-01-01 00:00:00

  • Preserving cognition, quality of life, physical health and functional ability in Alzheimer's disease: the effect of physical exercise (ADEX trial): rationale and design.

    abstract:BACKGROUND:Exercise is hypothesized to improve cognition, physical performance, functional ability and quality of life, but evidence is scarce. Previous studies were of short duration, often underpowered and involving home-based light exercise programs in patients with undefined dementia. The aim of the ADEX ('Preservi...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Hoffmann K,Frederiksen KS,Sobol NA,Beyer N,Vogel A,Simonsen AH,Johannsen P,Lolk A,Terkelsen O,Cotman CW,Hasselbalch SG,Waldemar G

    更新日期:2013-01-01 00:00:00

  • Association between Use of Statin and Risk of Dementia: A Meta-Analysis of Observational Studies.

    abstract:BACKGROUND AND AIMS:The impact of statin on dementia risk reduction has been a subject of debate over the last decade, but the evidence remains inconclusive. Therefore, we performed a meta-analysis of relevant observational studies to quantify the magnitude of the association between statin therapy and the risk of deme...


    pub_type: 杂志文章


    authors: Poly TN,Islam MM,Walther BA,Yang HC,Wu CC,Lin MC,Li YC

    更新日期:2020-01-01 00:00:00

  • Conscientiousness Is Associated with Lower Risk of Dementia among Black and White Older Adults.

    abstract:BACKGROUND:While some personality traits may reduce risk of dementia, this is controversial and has not been studied as much among diverse populations. We examined associations between 2 traits - Conscientiousness and Openness to Experience - and risk of dementia among black and white older adults. METHODS:We studied ...


    pub_type: 杂志文章


    authors: Kaup AR,Harmell AL,Yaffe K

    更新日期:2019-01-01 00:00:00

  • Cerebral haemodynamics in the elderly: the rotterdam study.

    abstract::Transcranial Doppler ultrasonography allows the non-invasive assessment of cerebral haemodynamics. Data on the frequency distribution of these parameters in the oldest old are scarce, which makes a distinction between physiological and pathophysiological ageing difficult. We studied the relation between cerebral haemo...


    pub_type: 杂志文章


    authors: Bakker SL,de Leeuw FE,den Heijer T,Koudstaal PJ,Hofman A,Breteler MM

    更新日期:2004-07-01 00:00:00

  • Primary intracranial tumors in the province of Trento-Italy (1977-1984). Distribution by administrative units.

    abstract::The incidence rate for primary intracranial neoplasms in the province of Trento (Italy) is 8.5/100,000/year, but the figures in the eleven administrative units ('comprensori') are different. The increased rates in C6 Val di Non and C10 Vallagarina are mainly due to the number of malignant tumors in the 45- to 64-year-...


    pub_type: 杂志文章


    authors: Ferrari G,Lovaste MG

    更新日期:1986-01-01 00:00:00

  • Factors influencing long-term survival and disability among three-month stroke survivors.

    abstract::216 survivors of acute stroke were studied 3 months postictus to determine predictors of long-term survival and disability 20 months after the initial stroke. Factors predicting mortality were, in order of importance, old age, a history of ischaemic heart disease, low mental-test score, low serum cholesterol concentra...


    pub_type: 杂志文章


    authors: Woo J,Kay R,Yuen YK,Nicholls MG

    更新日期:1992-01-01 00:00:00