Short Sitting Height and Low Relative Sitting Height Are Associated with Severe Cognitive Impairment among Older Women in an Urban Community in China.

Abstract:

BACKGROUND:Anthropometric indexes are powerful indicators of the environment and the plasticity of the human body. This study aimed at exploring the anthropometric indexes that are associated with late-life cognition impairment among the elderly Chinese in the Shanghai Aging Study. METHODS:The height, weight, and sitting height of 3,741 participants were measured. Participants were diagnosed with 'dementia', 'mild cognitive impairment', or 'cognitive normal' by neurologists using DSM-IV and Petersen criteria. Logistic regression was used to evaluate the association between height, sitting height, leg length or relative sitting height and cognitive function. RESULTS:Participants with dementia had the shortest body height (mean 157.2 cm, SD 9.1), the shortest sitting height (mean 81.8 cm, SD 5.6), and the lowest relative sitting height (mean 52.0 cm, SD 1.9). After adjustment for age, gender, education, lifestyles, medical history, apolipoprotein genotype and weight, shorter sitting height (OR 1.08, 95% CI 1.01-1.16 per cm), longer leg length (OR 0.93, 95% CI 0.88-0.99 per cm), and lower relative sitting height (OR 1.17, 95% CI 1.04-1.31 per 1%) were found to be significantly associated with dementia in older women. CONCLUSIONS:The potential risks for late-life severe cognitive impairment may be related to health problems in childhood and slow growth during puberty in women.

journal_name

Neuroepidemiology

journal_title

Neuroepidemiology

authors

Liang X,Li X,Ding D,Zhao Q,Luo J,Guo Q,Hong Z

doi

10.1159/000439569

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

257-63

issue

4

eissn

0251-5350

issn

1423-0208

pii

000439569

journal_volume

45

pub_type

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