Abstract:
:Infectious viruses and bacteria can trigger multiple sclerosis (MS) exacerbations. Seasonally changing concentrations of ambient air pollutants are known to predispose to transmissible infections, to induce systemic immune responses and to enhance existing peripheral inflammation. Ambient air quality and monthly MS relapse occurrence in south-western Finland were compared by multivariate logistic regression. The odds ratio of the risk of a relapse onset was over fourfold (4.143, p < 0.001) when the concentration of inhalable particulate matter (PM(10)) was at the highest quartile. Inhalable airborne particulate matter concentrations were connected to relapse occurrence. Poor air quality may enhance the seasonal changes in MS relapse occurrence by an increased susceptibility to transmissible infections.
journal_name
Neuroepidemiologyjournal_title
Neuroepidemiologyauthors
Oikonen M,Laaksonen M,Laippala P,Oksaranta O,Lilius EM,Lindgren S,Rantio-Lehtimäki A,Anttinen A,Koski K,Erälinna JPdoi
10.1159/000067108subject
Has Abstractpub_date
2003-01-01 00:00:00pages
95-9issue
1eissn
0251-5350issn
1423-0208pii
67108journal_volume
22pub_type
杂志文章abstract::Parkinson's and Alzheimer's diseases are age-related degenerative disorders that share common clinical, pathological and biochemical features. Epidemiological studies demonstrate a similar distribution of the disease in place and time. Causes of death and populations at higher risk are similar. These findings suggest ...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
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abstract:BACKGROUND:Brain tumours (BT) are one of the most frequent tumour types in young people, although little is known about their risk factors. OBJECTIVE:The objective of the current work was to review and summarize the scientific literature concerning exposure to environmental factors and BT risk in young people (<25 yea...
journal_title:Neuroepidemiology
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abstract::Trends of multiple sclerosis mortality in Spain from 1951 to 1997 are examined. Age-adjusted mortality strongly decreased from 3.08 per 100,000 women in 1951-1967 to 0.59 in 1968-1980 (similar figures were obtained for men). This decrease seems to be due to an artifact produced by changes in codification of causes of ...
journal_title:Neuroepidemiology
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journal_title:Neuroepidemiology
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abstract::This paper describes a proposed study to investigate the incidence of dementia in a population of over 75 year olds in Melton Mowbray, Leicestershire, England. The study population (n = 438) underwent a detailed psychiatric assessment using the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX) as the ...
journal_title:Neuroepidemiology
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journal_title:Neuroepidemiology
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doi:10.1159/000341411
更新日期:2013-01-01 00:00:00
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journal_title:Neuroepidemiology
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journal_title:Neuroepidemiology
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journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109502
更新日期:2007-01-01 00:00:00
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更新日期:2017-01-01 00:00:00
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journal_title:Neuroepidemiology
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更新日期:2013-01-01 00:00:00
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更新日期:1985-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
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journal_title:Neuroepidemiology
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2012-01-01 00:00:00
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journal_title:Neuroepidemiology
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