Incidence of dementia in very elderly individuals: a clinical, neuropathological and molecular genetic study.

abstract：:Most available data on the prognosis of epileptic seizures come from hospital-based clinics in which patients with chronic or severe disease are over-represented. The National General Practice Study of Epilepsy and Epileptic Seizures is a large prospective community-based study of people with newly diagnosed seizures ...

journal_title：Neuroepidemiology

authors： Hart YM,Sander JW,Sharvon SD

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Transversal studies have underlined the association between the decline in autonomic nervous system (ANS) activity and all-cause mortality. However, the predictive value of ANS has never been prospectively assessed in a general population-based cohort. METHOD:The PROOF (PROgnostic indicator OF cardiovascula...

journal_title：Neuroepidemiology

authors： Barthélémy JC,Pichot V,Dauphinot V,Celle S,Laurent B,Garcin A,Maudoux D,Kerleroux J,Lacour JR,Kossovsky M,Gaspoz JM,Roche F

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Previous studies suggested a decreased risk of cancer among patients with Alzheimer's disease (AD). There is still a lack of data on the specific types of cancer, the risk factors, and the impact of cholinesterase inhibitors on developing cancer in AD. METHODS:We performed a nationwide population-based stud...

journal_title：Neuroepidemiology

authors： Ou SM,Lee YJ,Hu YW,Liu CJ,Chen TJ,Fuh JL,Wang SJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:No epidemiological studies on the prevalence of compressive neuropathy have been undertaken in Arab countries. The aim of the study was to estimate the prevalence of the most common types of compressive neuropathies in Qena governorate/Egypt. METHODS:The study was part of a community-based survey carried ou...

journal_title：Neuroepidemiology

authors： Khedr EM,Fawi G,Allah Abbas MA,El-Fetoh NA,Zaki AF,Gamea A

更新日期：2016-01-01 00:00:00

abstract：AIMS:In order to examine the hypothesis that elevated resting heart rate (RHR) is associated with impaired cognitive score, we investigated the relationship between RHR and cognitive score in middle-aged, elderly and old Danish subjects from the general population. METHODS:Composite cognitive scores derived from the r...

journal_title：Neuroepidemiology

authors： Wod M,Jensen MT,Galatius S,Hjelmborg JB,Jensen GB,Christensen K

更新日期：2018-01-01 00:00:00

abstract：:From July 1988 to June 1989, the etiology was registered of 520 patients with generalized neuropathy in 5 neurological centers in Taiwan. The neuropathy was diabetic in 256 cases (49.23%), alcoholic in 45 (8.65%), inflammatory in 34 (6.53%; including 21 with acute inflammatory demyelinating polyneuropathy, 12 with chr...

journal_title：Neuroepidemiology

authors： Lin KP,Kwan SY,Chen SY,Chen SS,Yeung KB,Chia LG,Wu ZA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Several studies conducted in hospital emergency departments have shown that most patients delay in responding to stroke symptoms. In the general population, recognition of stroke and the appropriate reactions are important for prevention and acute treatment, particularly in areas with a high stroke incidence...

journal_title：Neuroepidemiology

authors： Moreira E,Correia M,Magalhães R,Silva MC

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To determine the age and sex variations in the relationship between diabetes and stroke. METHODS:This analysis was based on data from 61,327 Canadians > or =45 years of age who participated in the Canadian Community Health Survey in 2000-2001. Logistic regression analysis was conducted to evaluate the associ...

journal_title：Neuroepidemiology

authors： Lin M,Chen Y,Sigal RJ

更新日期：2007-01-01 00:00:00

abstract：:Using a case-control method, we studied the role of environmental risk factors and viral infection in the development of Parkinson's disease (PD) in China. Ninety-three PD patients and 186 controls were investigated with a questionnaire and from most of them, blood was taken to test the antibody levels of four virus (...

journal_title：Neuroepidemiology

authors： Wang WZ,Fang XH,Cheng XM,Jiang DH,Lin ZJ

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To assess the knowledge of stroke in the general public in the Gulf Cooperation Council (GCC) countries. BACKGROUND:The Arabian Gulf is a rapidly developing part of the world with major changes in the lifestyle that can increase the risk of stroke. To design effective stroke treatment and prevention strategi...

journal_title：Neuroepidemiology

authors： Kamran S,Bener AB,Deleu D,Khoja W,Jumma M,Al Shubali A,Inshashi J,Sharouqi I,Al Khabouri J

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Systematic reviews and meta-analyses on the incidence and prevalence of neurological conditions are important methods of quantifying the burden and risk of disease. METHODS:The rigorous methodology required in order to minimize publication bias, account for study heterogeneity, and variation in study qualit...

journal_title：Neuroepidemiology

authors： Fiest KM,Pringsheim T,Patten SB,Svenson LW,Jetté N

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Globally 15 million people have an acute stroke every year and one third of them die secondary to stroke events. Most research on stroke prevention and treatment is done in developed countries, yet more than 85% of strokes occur in developing countries. In particular, stroke remains an underrecognized cause ...

journal_title：Neuroepidemiology

authors： Kulshreshtha A,Anderson LM,Goyal A,Keenan NL

更新日期：2012-01-01 00:00:00

abstract：:Trends of multiple sclerosis mortality in Spain from 1951 to 1997 are examined. Age-adjusted mortality strongly decreased from 3.08 per 100,000 women in 1951-1967 to 0.59 in 1968-1980 (similar figures were obtained for men). This decrease seems to be due to an artifact produced by changes in codification of causes of ...

journal_title：Neuroepidemiology

authors： Llorca J,Guerrero-Alonso P,Prieto-Salceda D

更新日期：2005-01-01 00:00:00

abstract：:White matter lesions (WMLs) detected by cerebral magnetic resonance imaging (MRI) are putatively a consequence of cerebral hypoperfusion or ischemia. We investigated the prevalence, severity and correlates of WMLs in a population-based sample of 1,920 African-American and European-American men and women aged 55-72 yea...

journal_title：Neuroepidemiology

authors： Liao D,Cooper L,Cai J,Toole J,Bryan N,Burke G,Shahar E,Nieto J,Mosley T,Heiss G

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Studies on dyskinesia and Parkinson's syndrome associated with chronic kidney disease or end-stage renal disease (ESRD) have been mainly limited to case reports or case series studies. This population-based study investigated the risk of Parkinson's disease in patients with ESRD. METHODS:From a universal in...

journal_title：Neuroepidemiology

authors： Wang IK,Lin CL,Wu YY,Chou CY,Lin SY,Liu JH,Yen TH,Huang CC,Sung FC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Parkinson's disease (PD) is the most common neurodegenerative disease after Alzheimer's dementia. Whereas the exact etiology of PD remains unknown, risk of developing PD seems to be related to a combination of genetic and environmental factors. This also includes abnormal exposure to trace elements of nutrit...

journal_title：Neuroepidemiology

authors： Adani G,Filippini T,Michalke B,Vinceti M

更新日期：2020-01-01 00:00:00

abstract：:Although cognitive screening test scores change with advanced age, the significance of these changes (particularly decline in score) needs to be defined in terms of general health and neuropsychological functioning. Such analysis was undertaken in a subgroup of 287 healthy older men (mean age at baseline = 70.7 years)...

journal_title：Neuroepidemiology

authors： Eslinger PJ,Swan GE,Carmelli D

更新日期：2003-01-01 00:00:00

abstract：:A total of 186 cases of motor neuron disease (MND) was identified in two Danish counties during the period 1974-1986. The average annual incidence rate was 1.4/100,000 population, and the male:female ratio of incidence rates was 1.5. Mean age at diagnosis was 64.3 +/- 10.0 years. The incidence rates increased signific...

journal_title：Neuroepidemiology

authors： Højer-Pedersen E,Christensen PB,Jensen NB

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:We aimed to determine the accuracy of the iScore for predicting mortality and early disability following ischemic stroke in a French population-based study. METHODS:All patients with acute ischemic stroke were identified among residents of the city of Dijon, France, between 2006 and 2011, using a population...

journal_title：Neuroepidemiology

authors： Béjot Y,Jacquin A,Daubail B,Durier J,Giroud M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:White matter hyperintensities (WMHs) are a risk factor for stroke. Their etiology is considered to be cerebral microvascular abnormality. However, the association between WMHs and arteriosclerosis is not yet clear. The aim of this hospital-based cohort study was to identify the arteriosclerotic characteristi...

journal_title：Neuroepidemiology

authors： Saji N,Shimizu H,Kawarai T,Tadano M,Kita Y,Yokono K

更新日期：2011-01-01 00:00:00

abstract：:The previously reported prevalence of multiple sclerosis in Bulgaria is considerably lower than that reported for neighbouring countries. The aim of this study was to perform a detailed epidemiological investigation in well-defined populations in this country to obtain an accurate estimate of the frequency of multiple...

journal_title：Neuroepidemiology

authors： Milanov I,Georgiev D,Kmetska K,Jordanova L,Topalov N

更新日期：1997-01-01 00:00:00

abstract：:Homocysteine is a metabolite of methionine that may be remethylated by enzymes requiring folate and cobalamin (vitamin B12) to again form methionine or catabolized by the pyridoxine (vitamin B6) dependent enzyme, cystathionine beta synthase (CBS) to form cysteine (fig. 1) [1]. Homocysteine exists as a combination of v...

journal_title：Neuroepidemiology

authors： Sacco RL,Roberts JK,Jacobs BS

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The goal of this study was to assess the validity of a screening question for head tremor in essential tremor (ET). There are no published data on this topic, and the knowledge will guide future epidemiological investigations of this disorder. METHODS:These analyses utilized four distinct patient samples: a...

journal_title：Neuroepidemiology

authors： Louis ED,Michalec M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Charcot-Marie-Tooth disease (CMT) is a group of clinically and genetically heterogeneous disorders that primarily affect the peripheral nervous system. Epidemiological studies of CMT have not yet been performed in Korea. OBJECTIVES:This study was performed to estimate the prevalence of CMT in Korea and the ...

journal_title：Neuroepidemiology

authors： Park HJ,Choi YC,Oh JW,Yi SW

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:We validated a new method of identifying patients with incident myasthenia in automated Danish registers for the purpose of conducting epidemiological studies of the disorder. METHODS:For residents of a Danish county (population 484,862) in 1993-2008, we identified any hospital contacts coded for myasthenia...

journal_title：Neuroepidemiology

authors： Pedersen EG,Hallas J,Hansen K,Jensen PE,Gaist D

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Using data from a recent report that indicated a 2-fold higher risk of amyotrophic lateral sclerosis (ALS) among veterans of the 1991 Gulf War, we applied capture-recapture methodology to estimate possible under-ascertainment of ALS cases among deployed and non-deployed military personnel who were on active d...

journal_title：Neuroepidemiology

authors： Coffman CJ,Horner RD,Grambow SC,Lindquist J,VA Cooperative Studies Program Project #500.

更新日期：2005-01-01 00:00:00

abstract：:The Canadian Study of Health and Aging (CSHA) provided a population-based estimate of the prevalence of dementia of 8% for those aged 65 and older. Other studies have produced both higher and lower prevalence estimates. Factors that may contribute to these differences include: the use of or the reliance on neuropsycho...

journal_title：Neuroepidemiology

authors： Larrea FA,Fisk JD,Graham JE,Stadnyk K

更新日期：2000-05-01 00:00:00

abstract：:We consider the problem of testing that a disease with variable age at onset is an autosomal dominant or recessive genetic trait. Specific reference is made to Alzheimer's disease and recent publications proposing an autosomal dominant inheritance pattern. The pedigree structure allowed is restricted to first-degree r...

journal_title：Neuroepidemiology

authors： Sobel E,Davanipour Z,Alter M

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Hereditary cerebellar ataxias (HCA) and hereditary spastic paraplegias (HSP) are two groups of neurodegenerative disorders that usually present with progressive gait impairment, often leading to permanent disability. Advances in genetic research in the last decades have improved their diagnosis and brought n...

journal_title：Neuroepidemiology

authors： Ruano L,Melo C,Silva MC,Coutinho P

更新日期：2014-01-01 00:00:00

abstract：:Mortality rates for deaths 'due to' and 'with' hereditary ataxias are presented for the first time. Age-adjusted mortality rates were higher for whites than for nonwhites of either sex, and for men in both racial groups. Age-specific mortality rates for whites showed a peak for 'hereditary spinal ataxia' in the 20-29 ...

journal_title：Neuroepidemiology

authors： Leone M,Chandra V,Schoenberg BS

更新日期：1989-01-01 00:00:00