Estimating the occurrence of amyotrophic lateral sclerosis among Gulf War (1990-1991) veterans using capture-recapture methods.


OBJECTIVE:Using data from a recent report that indicated a 2-fold higher risk of amyotrophic lateral sclerosis (ALS) among veterans of the 1991 Gulf War, we applied capture-recapture methodology to estimate possible under-ascertainment of ALS cases among deployed and non-deployed military personnel who were on active duty during that war. STUDY DESIGN AND SETTING:One of the most serious concerns facing field epidemiological investigations is that of case ascertainment bias, particularly when it is differential among the study groups. Capture-recapture methods, however, have promise as an approach to assessing the impact of case ascertainment bias in such studies. To overcome potential limitations of any one approach, three different estimation methods were used: log-linear models, sample coverage, and ecological models, to obtain a comprehensive view of under-ascertainment bias in these populations. RESULTS:All three approaches indicated differential undercount of ALS cases with modest under-ascertainment likely to have occurred among non-deployed military personnel, but little under-ascertainment among the deployed. After correcting the rates for under-ascertainment, the age-adjusted risk of ALS remained elevated among military personnel who had been deployed to S.W. Asia during the 1991 Gulf War, confirming the earlier report. CONCLUSIONS:Capture-recapture methods are a useful approach to assessing the magnitude of case ascertainment bias in epidemiological studies from which ascertainment-adjusted estimates of rates and relative risks can be calculated.






Coffman CJ,Horner RD,Grambow SC,Lindquist J,VA Cooperative Studies Program Project #500.




Has Abstract


2005-01-01 00:00:00














  • Case-control study of Meige's syndrome. Result of a pilot study.

    abstract::A pilot case-control study was conducted to identify possible risk factors for Meige's syndrome. Patients with Meige's syndrome and age- and sex-matched controls suffering from other neurological diseases were recruited from the Movement Disorders Clinic and Neurology Outpatient Department of the All India Insititute ...


    pub_type: 杂志文章


    authors: Behari M,Sharma AK,Changkakoti S,Sharma N,Pandey RM

    更新日期:2000-09-01 00:00:00

  • Population-based epidemiological study of neurological diseases in Taiwan: I. Creutzfeldt-Jakob disease and multiple sclerosis.

    abstract:BACKGROUND:The purpose of the study is to investigate the epidemiology of Creutzfeldt-Jakob disease (CJD) and multiple sclerosis (MS) in Taiwan. METHODS:Cases of CJD and MS were identified from the National Health Insurance Research Database from January 2000 to December 2005. Age- and sex-specific incidences of these...


    pub_type: 杂志文章


    authors: Lai CH,Tseng HF

    更新日期:2009-01-01 00:00:00

  • Clinical and epidemiological aspects of Alzheimer's disease with presenile onset: a case control study.

    abstract::Little is known regarding the pathogenetic factors for Alzheimer's disease (AD). We studied 63 AD patients in order to evaluate if there were clinical subtypes of AD and whether prior illnesses and life-styles were involved in the development of the disease. In our patients selected for onset of symptoms before age 65...


    pub_type: 杂志文章


    authors: Ferini-Strambi L,Smirne S,Garancini P,Pinto P,Franceschi M

    更新日期:1990-01-01 00:00:00

  • The incidence of dementia and intake of animal products: preliminary findings from the Adventist Health Study.

    abstract::We investigated the relationship between animal product consumption and evidence of dementia in two cohort substudies. The first enrolled 272 California residents matched for age, sex, and zip code (1 vegan, 1 lacto-ovo-vegetarian, and 2 'heavy' meat eaters in each of 68 quartets). This design ensured a wide range of ...


    pub_type: 杂志文章


    authors: Giem P,Beeson WL,Fraser GE

    更新日期:1993-01-01 00:00:00

  • Spectrum of disease in vascular cognitive impairment.

    abstract::The recognition that cognitive impairment of vascular origin is not limited to multi-infarct dementia has led to the development of several sets of new criteria for vascular dementia (VaD). We set out to define the spectrum of disease in patients presenting with vascular cognitive impairment (VCI). Of 412 patients con...


    pub_type: 杂志文章


    authors: Rockwood K,Howard K,MacKnight C,Darvesh S

    更新日期:1999-01-01 00:00:00

  • Generalized neuropathy in Taiwan: an etiologic survey.

    abstract::From July 1988 to June 1989, the etiology was registered of 520 patients with generalized neuropathy in 5 neurological centers in Taiwan. The neuropathy was diabetic in 256 cases (49.23%), alcoholic in 45 (8.65%), inflammatory in 34 (6.53%; including 21 with acute inflammatory demyelinating polyneuropathy, 12 with chr...


    pub_type: 杂志文章,多中心研究


    authors: Lin KP,Kwan SY,Chen SY,Chen SS,Yeung KB,Chia LG,Wu ZA

    更新日期:1993-01-01 00:00:00

  • Socioeconomic position and cognitive function in the Seychelles: a life course analysis.

    abstract:OBJECTIVE:Poorer socioeconomic conditions early in life have been linked with memory, attention and learning deficits in adulthood, as well as with specific areas of educational achievement. It remains unclear, however, whether these distal associations are mediated by more current socioeconomic factors. In this study,...


    pub_type: 杂志文章


    authors: Kobrosly RW,van Wijngaarden E,Galea S,Cory-Slechta DA,Love T,Hong C,Shamlaye CF,Davidson PW

    更新日期:2011-01-01 00:00:00

  • Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease.

    abstract::The epsilon 4 allele of the apolipoprotein E (apoE) is associated with Alzheimer's disease (AD) and also with elevated serum total cholesterol and low-density lipoprotein levels. However, the interrelationships between apoE genotype, plasma cholesterol levels and AD risk have been studied very little. We examined the ...


    pub_type: 杂志文章


    authors: Notkola IL,Sulkava R,Pekkanen J,Erkinjuntti T,Ehnholm C,Kivinen P,Tuomilehto J,Nissinen A

    更新日期:1998-01-01 00:00:00

  • Epidemiologic approach to the study of dementing diseases: a nested case-control study in European incidence studies of dementia.

    abstract::In 1994 several European studies will have available risk factor information on incident cases of dementia collected in prospective community-based studies. These centers will collaborate in a nested-case control study based on the pooled cases and a sample of the non-diseased respondents. This paper describes the gen...


    pub_type: 杂志文章


    authors: Launer LJ,Brayne C,Breteler MM

    更新日期:1992-01-01 00:00:00

  • Creutzfeldt-Jakob disease in a recipient of a dura mater graft processed in the US: cause or coincidence?

    abstract::Iatrogenic Creutzfeldt-Jakob disease (CJD) has never been reported among recipients of dura mater grafts processed in the US. We recently investigated a report of such a case in a 72-year-old man with a typical clinical presentation of CJD. We found no evidence of CJD in either the 34-year-old donor or in other, proxi...


    pub_type: 杂志文章


    authors: Dobbins JG,Belay ED,Malecki J,Buck BE,Bell M,Cobb J,Schonberger LB

    更新日期:2000-03-01 00:00:00

  • Population-based distribution and psychometric properties of a short cognitive performance measure in the population-based Heinz Nixdorf Recall Study.

    abstract:BACKGROUND:Providing a valid and sensitive measure of different domains of cognitive performance in epidemiologic studies of early old-age populations presents a methodological challenge, given the broad range of variability in cognitive functioning in this age group. OBJECTIVES:(1) To provide data on the distribution...


    pub_type: 杂志文章


    authors: Wege N,Dlugaj M,Siegrist J,Dragano N,Erbel R,Jöckel KH,Moebus S,Weimar C,Heinz Nixdorf Recall Study Investigative Group.

    更新日期:2011-01-01 00:00:00

  • Familial coaggregation of Alzheimer's disease and Parkinson's disease: systematic review and meta-analysis.

    abstract:BACKGROUND:Familial aggregation has been shown for Alzheimer's disease (AD) and Parkinson's disease (PD) separately, and it has been hypothesized that these diseases also coaggregate in families. METHODS:The authors investigated familial coaggregation of AD and PD by conducting a systematic review and meta-analysis. P...


    pub_type: 杂志文章,meta分析,评审


    authors: Feldman AL,Johansson AL,Lambert PC,Sieurin J,Yang F,Pedersen NL,Wirdefeldt K

    更新日期:2014-01-01 00:00:00

  • Stroke awareness in urban and rural populations from northern Portugal: knowledge and action are independent.

    abstract:BACKGROUND:Several studies conducted in hospital emergency departments have shown that most patients delay in responding to stroke symptoms. In the general population, recognition of stroke and the appropriate reactions are important for prevention and acute treatment, particularly in areas with a high stroke incidence...


    pub_type: 杂志文章


    authors: Moreira E,Correia M,Magalhães R,Silva MC

    更新日期:2011-01-01 00:00:00

  • Identifying patients with myasthenia for epidemiological research by linkage of automated registers.

    abstract:BACKGROUND:We validated a new method of identifying patients with incident myasthenia in automated Danish registers for the purpose of conducting epidemiological studies of the disorder. METHODS:For residents of a Danish county (population 484,862) in 1993-2008, we identified any hospital contacts coded for myasthenia...


    pub_type: 杂志文章


    authors: Pedersen EG,Hallas J,Hansen K,Jensen PE,Gaist D

    更新日期:2011-01-01 00:00:00

  • Epidemiology of lissencephaly type I.

    abstract::In a cooperative study in The Netherlands 22 patients with lissencephaly type I were collected. In the period 1980-1988, the prevalence of lissencephaly type I in the Netherlands was 11.7 per million births (12.2 for females and 11.0 for males). The 5-year survival rate of patients with a complete or nearly complete a...


    pub_type: 杂志文章


    authors: de Rijk-van Andel JF,Arts WF,Hofman A,Staal A,Niermeijer MF

    更新日期:1991-01-01 00:00:00

  • Spatial distribution of stroke mortality in Spain, 1975-1986.

    abstract::Cerebrovascular diseases (CVDs) constitute the most frequent cause of death in Spain. In order to identify the geographical pattern of CVD mortality, age- and sex-specific as well as age-adjusted mortality rates (ICD-8,9 rubrics 430-438) were calculated for the period 1975-1986 for each province in the country. Maps w...


    pub_type: 杂志文章


    authors: Barrado-Lanzarote MJ,Almazan-Isla J,Medrano-Albero MJ,de Pedro-Cuesta J

    更新日期:1995-01-01 00:00:00

  • Alzheimer's disease and history of blood transfusion by apolipoprotein-E genotype.

    abstract::Some dementias, such as Creutzfeldt-Jakob disease, may result from transmissible agents. To assess the possibility of a blood-borne transmissible agent in Alzheimer's disease (AD), we compared informant-reported history of blood transfusions among 326 newly recognized probable AD cases and 330 control subjects of simi...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: O'Meara ES,Kukull WA,Schellenberg GD,Bowen JD,McCormick WC,Teri L,Pfanschmidt M,Thompson JD,Larson EB

    更新日期:1997-01-01 00:00:00

  • Plasma titers of antibodies against Epstein-Barr virus BZLF1 and risk of multiple sclerosis.

    abstract:BACKGROUND/AIMS:Results of recently conducted prospective studies have demonstrated that the presence of high titers of anti-EBNA-1 or anti-EBNA complex IgG antibodies in healthy individuals is a strong risk factor for multiple sclerosis (MS). Antibodies to BZLF1, the product of the homonymous early lytic gene, have be...


    pub_type: 杂志文章


    authors: Massa J,Munger KL,O'Reilly EJ,Falk KI,Ascherio A

    更新日期:2007-01-01 00:00:00

  • Creutzfeldt-Jakob disease in Japan: an epidemiological study done in a select prefecture between 1976 and 1986.

    abstract::An epidemiological study was performed with respect to Creutzfeldt-Jakob disease in a designated area in Japan. The subjects were observed in a small rural prefecture where the population generally remains within a limited radius throughout their lives. The patients' life-styles in each area were investigated in detai...


    pub_type: 杂志文章


    authors: Akai J,Ishihara O,Higuchi S

    更新日期:1989-01-01 00:00:00

  • Stroke and ischemic heart disease mortality trends in Brazil from 1979 to 1996.

    abstract::Stroke and ischemic heart disease (IHD) mortality rates were analyzed in Brazilian subjects older than 30 years of age from 1979 to 1996. Population estimates were based on census surveys. Mortality data were obtained from the Ministry of Health. For stroke, the age-adjusted death rate (ADR) dropped from 200 to 164 an...


    pub_type: 杂志文章


    authors: de Padua Mansur A,de Fátima Marinho do Souza M,Favarato D,Avakian SD,Machado César LA,Mendes Aldrigui J,Franchini Ramires JA

    更新日期:2003-05-01 00:00:00

  • Explanation and Elaboration of the Standards of Reporting of Neurological Disorders Checklist: A Guideline for the Reporting of Incidence and Prevalence Studies in Neuroepidemiology.

    abstract:BACKGROUND:Incidence and prevalence studies of neurological disorders play an extremely important role in hypothesis-generation, assessing the burden of disease and planning of health services. However, the assessment of disease estimates is hindered by the poor quality of reporting for such studies. We developed the S...


    pub_type: 杂志文章


    authors: Bennett DA,Brayne C,Feigin VL,Barker-Collo S,Brainin M,Davis D,Gallo V,Jetté N,Karch A,Kurtzke JF,Lavados PM,Logroscino G,Nagel G,Preux PM,Rothwell PM,Svenson LW

    更新日期:2015-01-01 00:00:00

  • Vascular disease among hospitalized multiple sclerosis patients.

    abstract:BACKGROUND:We examined the prevalence of cardiac and cerebrovascular disease among hospitalized patients with and without multiple sclerosis (MS). METHODS:This study used the Statewide Planning and Research Cooperate System data set of over 15 million hospitalizations in New York City from 1988 through 2002. We identi...


    pub_type: 杂志文章


    authors: Allen NB,Lichtman JH,Cohen HW,Fang J,Brass LM,Alderman MH

    更新日期:2008-01-01 00:00:00

  • Disability and mortality in a cohort of multiple sclerosis patients: a reappraisal.

    abstract::The aim of the study was to evaluate how the natural history of multiple sclerosis (MS) had changed over a 15-year period. We compared disability and mortality in a cohort of 83 MS patients hospitalised in the Neurological Institute of Pavia, northern Italy, from January 1, 1990, to December 31, 1991, with a similar c...


    pub_type: 杂志文章


    authors: Bergamaschi R,Montomoli C,Candeloro E,Fratti C,Citterio A,Cosi V

    更新日期:2005-01-01 00:00:00

  • Association between Hypertension and the Risk of Parkinson's Disease: A Meta-Analysis of Analytical Studies.

    abstract:BACKGROUND:The results of analytical studies show that the association between hypertension and the risk of Parkinson's disease (PD) remains controversial. METHOD:We searched studies related to the association between hypertension and the risk of PD. We pooled the ORs and risk ratios (RRs) with 95% confidence interval...


    pub_type: 杂志文章,meta分析


    authors: Chen J,Zhang C,Wu Y,Zhang D

    更新日期:2019-01-01 00:00:00

  • Mental health care use in Parkinson's disease: a record linkage study.

    abstract:BACKGROUND/AIM:Parkinson's disease (PD) is often complicated by psychiatric comorbidity, which is likely to lead to a higher use of mental health care facilities. In addition, psychiatric symptomatology and associated mental health care use may be present even before motor symptoms and PD are diagnosed, as the pathophy...


    pub_type: 杂志文章


    authors: Leentjens AF,Driessen G,Weber W,Drukker M,van Os J

    更新日期:2008-01-01 00:00:00

  • Decline and rise of mortality from motor neuron disease in Spain, 1960-1989: demographic, environmental and competitive influences.

    abstract::Mortality rates from motor neuron disease (MND) in Spain were analysed for the years 1960-1989, a period in which 3,530 deaths were recorded from the disease and during which the crude annual mortality rate ranged between 0.35 and 0.95 deaths per 100,000 persons. Whilst the crude mortality rate fell by 54% during the ...


    pub_type: 杂志文章


    authors: Neilson S,Robinson I,de Pedro-Cuesta J,Veiga-Cabo J

    更新日期:1996-01-01 00:00:00

  • Exposure to Medical Radiation during Fetal Life, Childhood and Adolescence and Risk of Brain Tumor in Young Age: Results from The MOBI-Kids Case-Control Study.

    abstract:BACKGROUND:We explored the association between ionizing radiation (IR) from pre-natal and post-natal radio-diagnostic procedures and brain cancer risk within the MOBI-kids study. METHODS:MOBI-kids is an international (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, New Zealand,...


    pub_type: 杂志文章


    authors: Pasqual E,Castaño-Vinyals G,Thierry-Chef I,Kojimahara N,Sim MR,Kundi M,Krewski D,Momoli F,Lacour B,Remen T,Radon K,Weinmann T,Petridou E,Moschovi M,Dikshit R,Sadetski S,Maule M,Farinotti M,Ha M,'t Mannetje A,Algua

    更新日期:2020-01-01 00:00:00

  • Clinical Expression of Multiple Sclerosis in Hispanic Whites of Primarily Caribbean Ancestry.

    abstract:OBJECTIVE:The clinical characteristics of multiple sclerosis (MS) are not well defined in Hispanic populations. We hypothesized that disease presentation in Hispanic white (HW) patients will be different from non-Hispanic white (NHW) patients given their ancestral background and reported lower disease prevalence. This ...


    pub_type: 杂志文章


    authors: Hadjixenofontos A,Beecham AH,Manrique CP,Pericak-Vance MA,Tornes L,Ortega M,Rammohan KW,McCauley JL,Delgado SR

    更新日期:2015-01-01 00:00:00

  • Ambient air quality and occurrence of multiple sclerosis relapse.

    abstract::Infectious viruses and bacteria can trigger multiple sclerosis (MS) exacerbations. Seasonally changing concentrations of ambient air pollutants are known to predispose to transmissible infections, to induce systemic immune responses and to enhance existing peripheral inflammation. Ambient air quality and monthly MS re...


    pub_type: 杂志文章


    authors: Oikonen M,Laaksonen M,Laippala P,Oksaranta O,Lilius EM,Lindgren S,Rantio-Lehtimäki A,Anttinen A,Koski K,Erälinna JP

    更新日期:2003-01-01 00:00:00

  • Short Sitting Height and Low Relative Sitting Height Are Associated with Severe Cognitive Impairment among Older Women in an Urban Community in China.

    abstract:BACKGROUND:Anthropometric indexes are powerful indicators of the environment and the plasticity of the human body. This study aimed at exploring the anthropometric indexes that are associated with late-life cognition impairment among the elderly Chinese in the Shanghai Aging Study. METHODS:The height, weight, and sitt...


    pub_type: 杂志文章


    authors: Liang X,Li X,Ding D,Zhao Q,Luo J,Guo Q,Hong Z

    更新日期:2015-01-01 00:00:00