Abstract:
OBJECTIVE:Using data from a recent report that indicated a 2-fold higher risk of amyotrophic lateral sclerosis (ALS) among veterans of the 1991 Gulf War, we applied capture-recapture methodology to estimate possible under-ascertainment of ALS cases among deployed and non-deployed military personnel who were on active duty during that war. STUDY DESIGN AND SETTING:One of the most serious concerns facing field epidemiological investigations is that of case ascertainment bias, particularly when it is differential among the study groups. Capture-recapture methods, however, have promise as an approach to assessing the impact of case ascertainment bias in such studies. To overcome potential limitations of any one approach, three different estimation methods were used: log-linear models, sample coverage, and ecological models, to obtain a comprehensive view of under-ascertainment bias in these populations. RESULTS:All three approaches indicated differential undercount of ALS cases with modest under-ascertainment likely to have occurred among non-deployed military personnel, but little under-ascertainment among the deployed. After correcting the rates for under-ascertainment, the age-adjusted risk of ALS remained elevated among military personnel who had been deployed to S.W. Asia during the 1991 Gulf War, confirming the earlier report. CONCLUSIONS:Capture-recapture methods are a useful approach to assessing the magnitude of case ascertainment bias in epidemiological studies from which ascertainment-adjusted estimates of rates and relative risks can be calculated.
journal_name
Neuroepidemiologyjournal_title
Neuroepidemiologyauthors
Coffman CJ,Horner RD,Grambow SC,Lindquist J,VA Cooperative Studies Program Project #500.doi
10.1159/000083297subject
Has Abstractpub_date
2005-01-01 00:00:00pages
141-50issue
3eissn
0251-5350issn
1423-0208pii
83297journal_volume
24pub_type
杂志文章abstract:AIM:We examined trends in incidence of stroke of any nature (ischemic and/or hemorrhagic) in subjects with a hospital diagnosis of nonvalvular atrial fibrillation or flutter in Denmark from 1980 to 2002 by sex, age and conditions of comorbidity. METHODS:We identified all individuals, aged 40-89 years, with an incident...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000092795
更新日期:2006-01-01 00:00:00
abstract::The multiple sclerosis (MS) mortality 1968-1977 in France, as reported by Alpérovitch and Bouvier, was tested for a possible correlation with a number of sociogeographic variables from relevant periods. The MS rate was associated with the main industry groups (metal processing and textile industry), with industry as a...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110759
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Transversal studies have underlined the association between the decline in autonomic nervous system (ANS) activity and all-cause mortality. However, the predictive value of ANS has never been prospectively assessed in a general population-based cohort. METHOD:The PROOF (PROgnostic indicator OF cardiovascula...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000108914
更新日期:2007-01-01 00:00:00
abstract::Iatrogenic Creutzfeldt-Jakob disease (CJD) has never been reported among recipients of dura mater grafts processed in the US. We recently investigated a report of such a case in a 72-year-old man with a typical clinical presentation of CJD. We found no evidence of CJD in either the 34-year-old donor or in other, proxi...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026240
更新日期:2000-03-01 00:00:00
abstract::Homocysteine is a metabolite of methionine that may be remethylated by enzymes requiring folate and cobalamin (vitamin B12) to again form methionine or catabolized by the pyridoxine (vitamin B6) dependent enzyme, cystathionine beta synthase (CBS) to form cysteine (fig. 1) [1]. Homocysteine exists as a combination of v...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
doi:10.1159/000026169
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:We explored the association between ionizing radiation (IR) from pre-natal and post-natal radio-diagnostic procedures and brain cancer risk within the MOBI-kids study. METHODS:MOBI-kids is an international (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, New Zealand,...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000506131
更新日期:2020-01-01 00:00:00
abstract::Previously, we studied the effect of population ancestry on the risk of multiple sclerosis (MS) in US veterans of World War II, comparing by state 1980 US census ancestry data with MS case/control ratios. Here, the joint effects of population ancestry and surname-derived ethnicity on MS risk are examined in the same s...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109804
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Patients with multiple sclerosis (MS) may have a higher risk of cardiovascular diseases (CVD) than the general population, but data are limited. METHODS:We conducted a population-based cohort study involving Danish citizens diagnosed with MS (n = 13,963) from 1977 to 2006 and an age- and sex-matched populat...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000320245
更新日期:2010-01-01 00:00:00
abstract::All death certificates with amyotrophic lateral sclerosis (ALS) or motor neuron disease (MND) as the primary or underlying cause occurring among Kentucky residents between 1964 and 1984 were manually reviewed. Geographic variability within Kentucky was evident for three intervals, 1964-1967, 1968-1978, and 1979-1984, ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110168
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:The purpose of the study is to investigate the epidemiology of Creutzfeldt-Jakob disease (CJD) and multiple sclerosis (MS) in Taiwan. METHODS:Cases of CJD and MS were identified from the National Health Insurance Research Database from January 2000 to December 2005. Age- and sex-specific incidences of these...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000229779
更新日期:2009-01-01 00:00:00
abstract::The multiple sclerosis (MS) prevalence rates in five districts of Bulgaria were compared with some geographic and climatic factors. In Bulgaria the latitude seems not to be a factor influencing the MS distribution. As to the climatic factors, a negative correlation was obtained between MS prevalence and mean annual su...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110106
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Parkinson's disease (PD) is the most common neurodegenerative disease after Alzheimer's dementia. Whereas the exact etiology of PD remains unknown, risk of developing PD seems to be related to a combination of genetic and environmental factors. This also includes abnormal exposure to trace elements of nutrit...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000502357
更新日期:2020-01-01 00:00:00
abstract::This paper presents the current status and use of virtual reality (VR) for children with attention deficit hyperactivity disorder (ADHD), autism and cerebral palsy. This literature review explores how VR systems have been used as treatment tools to address the primary impairments of these disorders. Three major classe...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
doi:10.1159/000320847
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The results of analytical studies show that the association between hypertension and the risk of Parkinson's disease (PD) remains controversial. METHOD:We searched studies related to the association between hypertension and the risk of PD. We pooled the ORs and risk ratios (RRs) with 95% confidence interval...
journal_title:Neuroepidemiology
pub_type: 杂志文章,meta分析
doi:10.1159/000496977
更新日期:2019-01-01 00:00:00
abstract::The epsilon 4 allele of the apolipoprotein E (apoE) is associated with Alzheimer's disease (AD) and also with elevated serum total cholesterol and low-density lipoprotein levels. However, the interrelationships between apoE genotype, plasma cholesterol levels and AD risk have been studied very little. We examined the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026149
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND AND METHODS:The high prevalence of epilepsy detected in rural Tanzania by Dr. Jilek-Aall since 1960, was verified by the World Health Organization (WHO) survey on neurological and seizure disorders. Neurologists and psychiatrists further interviewed both patients and controls using standard methods. The pres...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000054797
更新日期:2001-10-01 00:00:00
abstract::In 1994 several European studies will have available risk factor information on incident cases of dementia collected in prospective community-based studies. These centers will collaborate in a nested-case control study based on the pooled cases and a sample of the non-diseased respondents. This paper describes the gen...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000111005
更新日期:1992-01-01 00:00:00
abstract::We carried out a door-to-door survey in rural areas of the Cordillera Province, Bolivia, to determine the prevalence of the most common neurological diseases in a sample of about 10,000 inhabitants. A team of non-doctor health workers administered a standard screening instrument for neurological diseases, a slightly m...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000048624
更新日期:2002-03-01 00:00:00
abstract::Little is known regarding the pathogenetic factors for Alzheimer's disease (AD). We studied 63 AD patients in order to evaluate if there were clinical subtypes of AD and whether prior illnesses and life-styles were involved in the development of the disease. In our patients selected for onset of symptoms before age 65...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110750
更新日期:1990-01-01 00:00:00
abstract::This paper describes a proposed study to investigate the incidence of dementia in a population of over 75 year olds in Melton Mowbray, Leicestershire, England. The study population (n = 438) underwent a detailed psychiatric assessment using the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX) as the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110980
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND/AIMS:Brain tumors are the second most common pediatric malignancy. The literature suggests that one of the most common subtypes of malignant childhood brain tumor, medulloblastoma, has some seasonal variation in incidence by month of birth. METHODS:Data from cases in the Central Brain Tumor Registry of the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109502
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:While some personality traits may reduce risk of dementia, this is controversial and has not been studied as much among diverse populations. We examined associations between 2 traits - Conscientiousness and Openness to Experience - and risk of dementia among black and white older adults. METHODS:We studied ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000492821
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:No epidemiological studies on the prevalence of compressive neuropathy have been undertaken in Arab countries. The aim of the study was to estimate the prevalence of the most common types of compressive neuropathies in Qena governorate/Egypt. METHODS:The study was part of a community-based survey carried ou...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000444641
更新日期:2016-01-01 00:00:00
abstract::In neuroepidemiologic research, there are many pitfalls to trap unwary investigators, whether the project is a survey, a case-control study, or some other type of study. We briefly discuss pitfalls relating to: research preliminaries (e.g., failure to decide on study objectives); personnel and training (e.g., deficien...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
doi:10.1159/000026153
更新日期:1998-01-01 00:00:00
abstract::Recent reports of declining trends in mortality rates from cerebrovascular disease are based on underlying cause of death as stated on the death certificate, and may contain inaccuracies because death certificates are often completed without reference to all information in medical records, and because of changes in co...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110160
更新日期:1989-01-01 00:00:00
abstract::An increased risk for first-degree relatives (FDR) of glioma patients has previously been observed. The novel objective of this study was to investigate differences in familial risk among FDR of low-grade glioma (LGG) and high-grade glioma (HGG) cases, respectively. Two cohorts were constructed, one from 15,321 FDR of...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000065528
更新日期:2002-11-01 00:00:00
abstract::Some dementias, such as Creutzfeldt-Jakob disease, may result from transmissible agents. To assess the possibility of a blood-borne transmissible agent in Alzheimer's disease (AD), we compared informant-reported history of blood transfusions among 326 newly recognized probable AD cases and 330 control subjects of simi...
journal_title:Neuroepidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000109675
更新日期:1997-01-01 00:00:00
abstract::We explored the relationship between amyotrophic lateral sclerosis (ALS) and cigarette smoking in a case-control study conducted in New England from 1993 to 1996. Recently diagnosed ALS cases (n = 109) were recruited from two major referral centers. Population controls (n = 256) were identified by random telephone scr...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026211
更新日期:1999-01-01 00:00:00
abstract::The black Caribbean population continues to grow in the US and little is known about stroke etiologies in that community. We examined stroke subtypes in 175 consecutive Haitian-born patients living in Miami, admitted for acute stroke. Ischemic stroke was diagnosed in 72%. Small vessel occlusion was the most frequent s...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000087449
更新日期:2005-01-01 00:00:00
abstract::Using a case-control method, we studied the role of environmental risk factors and viral infection in the development of Parkinson's disease (PD) in China. Ninety-three PD patients and 186 controls were investigated with a questionnaire and from most of them, blood was taken to test the antibody levels of four virus (...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110319
更新日期:1993-01-01 00:00:00